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중소기업의 컨설팅 참여도 및 이해도와 컨설팅 재구매 의도와의 관계 연구
홍정훈(Hong, Jung-Hun),박상연(Park, Sang-Yun) 한국경영교육학회 2020 경영교육연구 Vol.35 No.4
[연구목적] 본 연구의 목적은 컨설팅을 받은 수진기업(受診企業)들을 대상으로 컨설팅 참여도 요인이 컨설팅 재구매 의도에 미치는 영향을 실증분석하는 것이다. 또한 수진기업의 당해 컨설팅에 대한 이해도가 컨설팅 재구매 의도에 대해 조절효과를 가지는지에 대해 추가적으로 분석한다. [연구방법] 본 연구에서는 기존에 수행되었던 관련 국내외 연구들에 대한 검토 및 관련 실무 담당진과의 면담을 통해 6개의 연구가설을 도출하였다. 이에 대한 검증을 위해 국내 중소기업의 컨설팅 참여도 · 이해도 및 컨설팅 재구매 의도에 관한 자료를 수집하였고, 수집된 자료에 대해서는 신뢰성과 타당성을 검토하였다. 또한 구조방정식 모형 분석을 통해 연구가설을 검증하였다. [연구결과] 연구 결과 컨설팅 재구매를 높이기 위해서는 수진기업의 참여도 제고와 함께 컨설팅 이해도를 높이는 노력이 동시에 필요함을 실증적으로 검증하였다. [연구의 시사점] 본 연구에서는 기존의 연구들에서 상대적으로 간과되었던 컨설팅 수진기업의 컨설팅 참여도 · 이해도 요인이 컨설팅 수행 성과 및 매출 증대와 관련하여 중요한 결정요인임을 실증적으로 분석하였다. 본 연구의 결과는 향후 관련 분야의 후속연구에 이론적, 실무적 시사점을 제공할 것으로 기대된다. [Purpose] This study empirically assessed the extent to which consulting companies have increased their participation in consulting in some cases or situations, and how this affects consulting repurchases. In addition, we empirically assessed whether clients’ understanding of consulting affects the intention of consulting repurchase. [Methodology] For this purpose, we described prior literature review and we examined various researches to provide understanding of relationships with strategic account. Six hypotheses were drawn from the previous researches. To verify these hypotheses, data were collected through survey, and the data were tested by reliability, validity, correlation, structural equation modeling analysis. [Findings] As a result of the study, it is proven that both customer participation and consulting understanding need to be enhanced to increase consulting repurchase. [Implications] This study can see that it is important to conduct the consulting in order to participate in the role and process of the client’s personnel and to improve the understanding of consulting.
Thick SmBCO/IBAD-MgO Coated Conductor for High Current Carrying Power Applications
Hong-Soo Ha,Jung-Hun Lee,Rock-Kil Ko,Ho-Sup Kim,Ho-Kyum Kim,Seung-Hyun Moon,Chan Park,Do-Jun Youm,Sang-Soo Oh IEEE 2010 IEEE transactions on applied superconductivity Vol.20 No.3
<P>Long-length (Sm<SUB>1+x</SUB>B<SUB>2-x</SUB>C<SUB>3</SUB>O<SUB>7-y</SUB>) coated conductor was fabricated using ion beam assisted deposition (IBAD)-MgO template (LaMnO<SUB>3</SUB>/IBAD - MgO/Y<SUB>2</SUB>O<SUB>3</SUB>/Al<SUB>2</SUB>O<SUB>3</SUB>/Hastelloy) by the reactive co-evaporation method for electric power applications. SmBCO superconducting layers with thicknesses from 1 to 3 ¿m were deposited to investigate the effect of SmBCO thickness on the in-plane texture, surface morphology and superconducting properties. In this study, the optimal deposition conditions were examined to make thick SmBCO coated conductor without degradation of critical current density. The oxygen partial pressure and temperature were controlled in the range of 1~20 mTorr and 600 ~ 800°C, respectively. SmBCO/IBAD-MgO coated conductors showed high critical current densities over 2.0 MA/cm<SUP>2</SUP> with small amount of degradation by increasing the thickness of superconducting layer up to 3 ¿m. The critical current of 637.5 A/cm-w (J<SUB>C</SUB> = 2.12 MA/cm<SUP>2</SUP>) at 77 K in self- field was obtained in 3 ¿m-thick and 1 m long coated conductor. This is the highest critical current reported so far of the coated conductor with SmBCO superconducting layer deposited by co-evaporation.</P>
( Hong Seon Son ),( Sung Hoon Choi ),( Na Eun Lee ),( Chang Hun Lee ),( Seung Young Seo ),( Seong Hun Kim ),( Sang Wook Kim ),( Seung Ok Lee ),( Soo Teik Lee ),( Dae Ghon Kim ),( In Hee Kim ) 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1
Aims: Tenofovir (TDF) entecavir (ETV) are considered as the preferred treatment options for treatment-naïve chronic hepatitis B (CHB) patients. We compared the virologic response and renal safety of long-term TDF versus ETV therapy in naïve CHB patients. Methods: This retrospective study included total 432 patients who were treated with TDF (n=205) or ETV (n=227) from August 2012 to March 2017. Virologic response (VR) was defined as undetectable serum HBV DNA by PCR (<20 IU/mL). Results: Mean age of patients, sex, baseline serum levels of AST, ALT, creatinine, and HBV DNA were not significantly different between TDF and ETV groups. The cumulative rates of VR between TDF and ETV groups were 71.6% vs. 61.8% (p=0.477), 88.1% vs. 79.6% (p=0.058), and 84.8% vs. 83.7% (p=0.966) at 1, 2, and 3 years, respectively. The cumulative rates of genotypic resistance between TDF and ETV groups were 0% vs. 0%, 0% vs. 1.5% (p=0.404), and 0% vs. 2.2% (p=0.447) at 1, 2, and 3 years, respectively. Incidences of renal impairment and hypophosphatemia during treatment up to 3 years were not significantly different between two groups. Multivariate analysis showed that HBeAg-positivity (OR 0.27, 95% CI 0.12-0.58, p=0.0012) and serum HBV DNA at 1 year 2000 IU/mL (OR 0.09, 95% CI 0.03-0.25, p<0.0001) were significantly associated with VR. Conclusions: Long-term TDF and ETV treatments appear to have similar virologic response and renal safety in naïve CHB patient. However, long-term ETV therapy might to be associated with genotypic resistance in 2.2% up to 3 years, while none of patients on TDF therapy did.
Sang Ah Yi,Jieun Lee,Sun Kyu Park,Jeom Yong Kim,Jong Woo Park,Min Gyu Lee,Ki Hong Nam,Jee Hun Park,Hwamok Oh,Saetbyul Kim,Jihoon Han,Bo Kyung Kim,Dong-Gyu Jo,Jeung-Whan Han 고려인삼학회 2020 Journal of Ginseng Research Vol.44 No.1
Background: The biological and pharmacological effects of BST204, a fermented ginseng extract, havebeen reported in various disease conditions. However, its molecular action in metabolic disease remainspoorly understood. In this study, we identified the antiadipogenic activity of BST204 resulting from itsinhibition of the S6 kinase 1 (S6K1) signaling pathway. Methods: The inhibitory effects of BST204 on S6K1 signaling were investigated by immunoblot, nuclearfractionation, immunoprecipitation analyses. The antiadipogenic effect of BST204 was evaluated bymeasuring mRNA levels of adipogenic genes and by chromatin immunoprecipitation and quantitativereal-time polymerase chain reaction analysis. Results: Treatment with BST204 inhibited activation and nuclear translocation of S6K1, furtherdecreasing the interaction between S6K1 and histone H2B in 10T1/2 mesenchymal stem cells. Subsequently,phosphorylation of H2B at serine 36 (H2BS36p) by S6K1 was reduced by BST204, inducing anincrease in the mRNA expression of Wnt6, Wnt10a, and Wnt10b, which disturbed adipogenic differentiationand promoted myogenic and early osteogenic gene expression. Consistently, BST204 treatmentduring adipogenic commitment suppressed the expression of adipogenic marker genes and lipid dropformation. Conclusion: Our results indicate that BST204 blocks adipogenesis of mesenchymal stem cells through theinhibition of S6K1-mediated histone phosphorylation. This study suggests the potential therapeuticstrategy using BST204 to combat obesity and musculoskeletal diseases.
Colon Transit Time May Predict Inadequate Bowel Preparation in Patients With Chronic Constipation
( Hong Jun Park ),( Myeong Hun Chae ),( Hyun Soo Kim ),( Jae Woo Kim ),( Moon Young Kim ),( Soon Koo Baik ),( Sang Ok Kwon ),( Hee Man Kim ),( Kyong Joo Lee ) 대한장연구학회 2015 Intestinal Research Vol.13 No.4
Background/Aims: We evaluated whether colonic transit time (CTT) can predict the degree of bowel preparation in patients with chronic constipation undergoing scheduled colonoscopy in order to assist in the development of better bowel preparation strategies for these patients. Methods: We analyzed the records of 160 patients with chronic constipation from March 2007 to November 2012. We enrolled patients who had undergone a CTT test followed by colonoscopy. We defined patients with a CTT ≥30 hours as the slow transit time (STT) group, and patients with a CTT <30 hours as the normal transit time (NTT) group. Boston Bowel Preparation Scale (BBPS) scores were compared between the STT and NTT groups. Results: Of 160 patients with chronic constipation, 82 (51%) were included in the STT group and 78 (49%) were included in the NTT group. Patients with a BBPS score of <6 were more prevalent in the STT group than in the NTT group (31.7% vs. 10.3%, P=0.001). Multivariate analysis showed that slow CTT was an independent predictor of inadequate bowel preparation (odds ratio, 0.261; 95% confidence interval, 0.107-0.634; P=0.003). The best CTT cut-off value for predicting inadequate bowel preparation in patients with chronic constipation was 37 hours, as determined by receiver operator characteristic (ROC) curve analysis (area under the ROC curve: 0.676, specificity: 0.735, sensitivity: 0.643). Conclusions: Patients with chronic constipation and a CTT >30 hours were at risk for inadequate bowel preparation. CTT measured prior to colonoscopy could be useful for developing individualized strategies for bowel preparation in patients with slow CTT, as these patients are likely to have inadequate bowel preparation. (Intest Res 2015;13:339-345)
Sang Wook Kim(김상욱),Mi Rang Lee(이미랑),Han Seok Kang(강한석),Seon Ku Kim(김선구),Teak Soon Shin(신택순),Hong Gu Lee(이홍구),Hae Yeal Jeon(전해열),Kwan Suk Kim(김관석),Chang Hee Do(도창희),Bong Hwan Choi(최봉환),Tae Hun Kim(김태헌) 한국생명과학회 2008 생명과학회지 Vol.18 No.6
돼지 2번 염색체의 육질 관련 양적 경제형질에 관한 연구보고가 몇몇 이루어 지고 있다. 양돈업계에서 DNA 기술을 이용한 염색체 정보를 활용하기 위해 본 연구에서는 13개의 후보 유전자에서 생성된 중합효소연쇄반응(PCR) 생성물을 비교 재서열 함으로써 단일염기변이(SNP) 표지들을 개발했다. 11개의 중합효소연쇄반응 생성물에서 296 bp마다 에서 평균 하나의 SNP, 총 34개의 SNP를 발견하였다. 또한 11개의 SNP에 대해 PCR 제한효소 길이 절편길이 다형성(RFLP) 분석을 전개한 후, 이를 대한민국 상업돈 4품종 개체군의 유전자형을 분석하는데 활용하였다. 본 연구는 유용한 단일염기변이를 식별하고 돼지 개체군 내 경제적으로 중요한 특성들과 SNP의 연관성을 확인하는 데 그 목적이 있다. Several studies reported quantitative trait loci (QTL) for meat quality on porcine chromosome 2. For application of the chromosomal information to pig industry through using DNA technology, single nucleotide polymorphism (SNP) markers are developed by comparative re-sequencing of polymerase chain reaction (PCR) products of 13 candidate genes. A total of 34 SNPs were identified in 11 PCR products, an average of one SNP in every 296 bp.PCR restriction fragment length polymorphism (RFLP) assays were developed for 11 SNPs and used to genotype four commercial pig populations in Korea. The SNP markers were used to map candidate genes in QTL and to clarify the relevance of SNP and quantitative traits.