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        Adaptive smith predictor controller for total intravenous anesthesia automation

        Bhavina Patel,Hiren Patel,Pragna Vachhrajani,Divyang Shah,Alpesh Sarvaia 대한의용생체공학회 2019 Biomedical Engineering Letters (BMEL) Vol.9 No.1

        Anesthetic agent propofol needs to be administered at an appropriate rate to prevent hypotension and postoperative adversereactions. To comprehend more suitable anesthetic drug rate during surgery is a crucial aspect. The main objective of thisproposal is to design robust automated control system that work effi ciently in most of the patients with smooth BIS andminimum variations of propofol during surgery to avoid adverse post reactions and instability of anesthetic parameters. And also, to design advanced computer control system that improves the health of patient with short recovery time and lessclinical expenditures. Unlike existing research work, this system administrates propofol as a hypnotic drug to regulate BIS,with fast bolus infusion in induction phase and slow continuous infusion in maintenance phase of anesthesia. The novelty ofthe paper lies in possibility to simplify the drug sensitivity-based adaption with infusion delay approach to achieve closedloopcontrol of hypnosis during surgery. Proposed work uses a brain concentration as a feedback signal in place of the BISsignal. Regression model based estimated sensitivity parameters are used for adaption to avoid BIS signal based frequentadaption procedure and large off set error. Adaptive smith predictor with lead–lag fi lter approach is applied on 22 diff erentpatients’ model identifi ed by actual clinical data. The actual BIS and propofol infusion signals recorded during clinical trialswere used to estimate patient’s sensitivity parameters EC 50 and λ . Simulation results indicate that patient’s drug sensitivityparameters based adaptive strategy facilitates optimal controller performance in most of the patients. Results are obtainedwith proposed scheme having less settling time, BIS oscillations and small off set error leads to adequate depth of anesthesia. A comparison with manual control mode and previously reported system shows that proposed system achieves reductionin the total variations of the propofol dose. Proposed adaptive scheme provides better performance with less oscillation inspite of computation delay, surgical stimulations and patient variability. Proposed scheme also provides improvement inrobustness and may be suitable for clinical practices.

      • Symbolic indicators and user perception performance in Indian industries and Public places

        Rauf Iqbal,Hiren Shah,Amitabha De,Suman Mukhopadhyay 대한인간공학회 2014 대한인간공학회 학술대회논문집 Vol.2014 No.5

        During the past two decades, the body of empirical research on warning design and evaluation has grown steadily. Consequently, there are now basic principles and guidelines addressing warning design and how to enhance the usability of designs by considering factors internal to the user e.g., beliefs, perceptions of risk and stress. Industrial & public safety icons need to be more recognizable due to globalisation and liberalisation of economies and due necessity to communicate message effectively and effortlessly. Many a times industrial & public safety icons are not recognized, which result in accident, injury and loss. A study was carried out to investigate the recognition rate of symbolic indicators by select industrial workforce and to evaluate whether the icons encountered in “every-day activities” met the comprehension criteria of ISO Standards. The study was conducted on 37 males and 53 females belonging to various age groups and qualification level. The study included 60 icons used in industry (n=30) and public places (n=30). A paper-based icon recognition questionnaire was prepared and used to examine icon recognition and perception performance over different groups. Each icon was given a unique code for its identification which the participant needed to search out from the codes given below the corresponding icon and fill it in their response sheet. Results show that failure rate to recognize icons used in industrial operations are much higher than the icons used in public places. Recognition rate of 50% industrial icons have been found below the recognition rate as stated in ISO standard (>67%). Results of ANOVA for industrial icons show that recognition rate varies with educational background (p<0.008), educational back ground and gender (p<0.04), gender and age group (p<0.03). But is case of public icons there were no significant difference among gender, age and educational background in comprehension of icons. Safety icons are designed to increase customer and worker safety, problems occur if the icons are failed to click human recognition. An effective symbol must be easily distinguishable compared with others. The challenge during design is to foreseeing cognition ability of the users’ across age, sex and social background. In industrial situation, workers should be exposed to training - especially when they work in environments that expose them to hazards of various kinds.

      • Symbolic Indicators and User Perception Performance in Indian Industries and Public Places

        ( Rauf Iqbal ),( Hiren Shah ),( Amitabha De ),( Suman Mukhopadhyay ) 한국감성과학회 2014 춘계학술대회 Vol.2014 No.-

        During the past two decades, the body of empirical research on warning design and evaluation has grown steadily. Consequently, there are now basic principles and guidelines addressing warning design and how to enhance the usability of designs by considering factors internal to the user e.g., beliefs, perceptions of risk and stress. Industrial & public safety icons need to be more recognizable due to globalisation and liberalisation of economies and due necessity to communicate message effectively and effortlessly. Many a times industrial & public safety icons are not recognized, which result in accident, injury and loss. A study was carried out to investigate the recognition rate of symbolic indicators by select industrial workforce and to evaluate whether the icons encountered in every-day activities met the comprehension criteria of ISO Standards. The study was conducted on 37 males and 53 females belonging to various age groups and qualification level. The study included 60 icons used in industry (n=30) and public places (n=30). A paper-based icon recognition questionnaire was prepared and used to examine icon recognition and perception performance over different groups. Each icon was given a unique code for its identification which the participant needed to search out from the codes given below the corresponding icon and fill it in their response sheet. Results show that failure rate to recognize icons used in industrial operations are much higher than the icons used in public places.

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