漆木灰 授與가 家兎의 實驗的 肝 障碍에 미치는 影響

金完熙,卞廷煥,李學仁 경산대학교 제한동의학술원 1975 濟韓 Vol.2 No.-

An epperimental study administration of chilmokhee powder effected on the liver cirrhosis of the Rabblits. Wan Hee, Kim, Jung whan, Byun., Hack In, Lee, O.M.D. Division of oriental medicin, Achool of medicin Kyung Hee University. The author studied the effect of Allyl Alcohol by the dosage of 1.0㎖ per kg body weight to the rabbits weighing 2kg or more, liver function tests were performed after the administration of Allyl Alcohol and after treatment of chilmokhee powder. The liver function tests performed in this study included serum SGPT, SGOT, protein choles terol, L.D.H. The results were as follow. 1) After administration of Allyl Alcolhol 24hrs become a Liver eirhosis if the raglits 2) After administration of Allyl Alcolhol 72hrs reached high peak of liver cirrhosis and it is recovered gratuadly. 3) After treat of chilmokhoe powder recoverd almost normal condition.

[cis-Cr(III)(5,5,7,12,12,14-hexamethy1-1,4,8,11-tetraazacyclotetradecane)(L_(a))_(n)]CLO_(4)(n = 1 or 2)합성과 성질

변종철,한성빈,정덕상,임희정,한충훈 濟州大學校 師範大學 科學敎育硏究所 1995 科學敎育 Vol.12 No.1

rac-5.5.7.12.12.14-hexamethy1-1,4,8,11-tetraazacyclotetradecane hydrate : Lm·H_(2)O was prepared and separated from the corresponding meso-isomer dihydrate according to the Curtis method. The racisomer was confirmed by spectroscopic data of NMR and IR spectroscopy. To synthesize the [CrL_m(OH)₂] complex. the racemic compound purified from meso and racemic mixture was reacted with Cr(II1) salt. The complx ion species {[SrL_m(OH)_(2)]^(+): λ_(max) = 613.0(ε_(max) = 116 M^(-1)cm^(-1)), {[CrLm(OH)(H_(2)O)]^(2+) : λ_(max) = 575.0nm(ε_(max) = 133M^(-1)cm^(-1)). [CrLm(H_(2)O)_(2)]^(3+) : λ_(max) = 532.0nm (ε_(max) = 172M^(-1)cm^(-1))} obtained from pH change of [CrLm(OH)_(2)(OH)_(3)]^(+) solution were confirmed from an electron absorption spectra. The result of the distribution diagram of chemical species proves that main products in the range of solution pH ≤ 3.5 . 3.5 <pH <7, and pH ≥ 7. are [CrLm(H_(2)O)_(2)]^(3+). [CrL_(m)(OH) (H_(2)O)^(2+). and [CrL_m(OH)_(2), respectively. At P~ 2.0, we synthesized several Cr(III)-macrocyclic complexes containing various axial ligands (L_(a) : I, Br^(-), CI^(-), S_(2)O_(3)^(2-), F^(-), malonate, NCS^-, oxalate) instead of H_(2)O. [CrL_m(OH_(2))]^(3+) + L_(a) →[CrL_(m)(L_(a))_(n)]^(+)(n = 1 or 2) Cr(III)-macrocyclic complexes combined with vaious ligands on the axial position were primarily confirmed with the mass spectrum. Especially, when the axial ligands are malonate, oxalate, and S_(2)O_(3)^(2-), a possible thermal decomposition reaction and redox potential are considered as follows: ◁표삽입▷(본문을 참조하세요) As well, a spectrochemical series was drawn up on the basis of the ligand field strength obtained from electron absorption spertra of the complexes, [CrL_(m)(La)_(n)]^(p+) F^(-), CI^(-) ~Br^(-)<I^(-)<S_(2)O_(3)^(2-)<OH^(-)<H_(2)O<mal~NCS^(-) We can expect that there is three d-d transition d^(3) ion Tanabe-Sugano diagram. ◁표삽입▷(본문을 참조하세요) However, we found only two trasitions because the other transition {^(4)A_(2)_g(F)→^(4)T_lg(P) : v_(3)} is obscured by absorption arising from charge transfer transition. ◁표삽입▷(본문을 참조하세요)

Exploring the Potential of Integrating Mobile Augmented Reality (AR) Into Speaking Performance Assessment

Byun,Jung-Hee 영상영어교육학회 2020 영상영어교육 (STEM journal) Vol.21 No.1

The study aims to explore the possibility of applying mobile AR technology into an English-speaking performance assessment as a new mode of delivery. It investigates the effect of the AR experience on test participants and the speaking constructs to be assessed, all of which affect the validity. The speaking assessment required 148 high school senior male students to create an AR-mediated art guide by recording a video art guide and projecting it onto a picture of Korean genre painting via the mobile AR authoring tool, “HP Reveal” (Hewlett Packard, 2018). Both quantitative methods of regression and factor analysis and qualitative methods of a questionnaire and interview were used to attain the research goal. The results offer empirical support to the validity of the newly designed assessment and reveal that integrating AR technology into language assessment could facilitate student learning in the assessment procedure and enhance student performance during the test as well as measure their speaking competence. Discussions and suggestions address the validation issue resulting from integrating technology skill with the language construct to be measured, the comparability with assessments of other modes such as listening, reading, and writing and the theoretical relevance to task-based language learning.

1,2-Benzisothiazol-3-one-1,1-Dioxide 유도체의 합성

정대일,정희철,변석인,이용균,박유미,최순규,한정태 東亞大學校附設基礎科學硏究所 2002 基礎科學硏究論文集 Vol.19 No.1

사카린 유도체는 제초제, 항독성, 살균제 등에 광범위하게 연구되어져 오고 있다. 새로운 농략 활성을 가진 물질을 합성하기 위해 먼저 선도물질로 사카린 1을 산화, 염소화 시킨 3-chloro-1,2-benzisothiazol-1,1-dioxide(BID-CI) 2와2cholromethy-1,2-benzisohizol-3-one1,1-dioxide 4를 합성하였다. 선도물질, amines, imidazoles, trones등과 반응시켜 다음과 같은 물질들을 얻었다. ; 3-cyclohexylamino-1,2-benzisothiazol-1,1-dioxide 6, 3-furylamino-1,2-benzisothiazol-1,1-dioxide 8, 3-(3-imidazol)-1,2-benzisothiazol-1,1-dioxide 10, 3-(2-methy-3-imidazol)-1,2-benzisothaizol-1,1-dioxide 12, 2-(3-imidazol)methy-1-1,2-benzisothiazol-3-one-1,1-dioxide 13, and 2-(-3-imidazol)methyl- 1,2-benzisothiazol-1,1-dioxide 14.

Kainic Acid로 유발된 경련이 흰쥐 대뇌피질의 Vasoactive Instestinal Polypeptide 신경세포에 미치는 영향에 관한 면역조직화학적 연구

허영범,변우현,이원규,김정혜,안희경 대한해부학회 1995 Anatomy & Cell Biology Vol.28 No.2

강화방법이 중년여성의 운동지속 및 건강에 미치는 영향

류호상,현정희,변재철,김한철 한국스포츠심리학회 2002 한국스포츠심리학회지 Vol.13 No.3

최근 10여년 동안 운동과학에 대한 다량의 문헌들에도 불구하고 여성들을 대상으로 운동지속(exercise adherence)과 운동효과에 대한 연구들은 많지 않다. 이 연구의 목적은 강화방법이 여성의 운동지속과 건강에 미치는 영향을 규명하기 위한 것이었다. 생활체육으로 에어로빅댄스를 하고자 방문한 31명의 중년여성들이 자신들이 원하는 세 개의 다론 시간대의 수업에 각각 등록을 하였다. 각 교실은 체지방 측정치로 피드백을 제공받는 집단(n=10), 출석이 양호할 시 에어로빅무용복을 보상받는 집단(n=11), 그리고 통제 집단(n=10)이 되어 실험에 참가하였다. 피험자들을 같은 강사의 지도로 하루에 45분, 주 5회(월-금), 8주 동안 에어로빅댄스를 실시하였다. 일원변량분석 결과 체지방으로 피드백을 제공받으며 운동한 집단은 다른 두 집단에 비해 높은 출석률을 보였다(p<.05). 공변량분석(ANCOVA)에서는 피드백 집단이 통제 집단보다 체지방율과 POMS의 총정서장애(Total mood disturbance)에서 유의하게 낮은 수치를 보였다(p<.05). 안면피부상태에서는 집단 간에 유의한 차이를 보이지 않았지만, 집단을 합한 운동 전·후간에는 차이가 있게 나타났다(p<.05). 이 연구는 생활체육 현장에서 피드백을 제공하여 강화를 시키면 중년여성들의 운동지속(exercise adherence)을 높일 수 있고 건강 증진에도 효과적이라는 결론에 도달하였다. 그 외 연구결과를 토대로 운동지속을 높이는 관점에서 논의가 이루어지고 장래연구를 위한 방향도 제시되었다. Despite decades of physical activity research, little is known about the patterns and effects of physical activity among women. The purpose of this research was to examine whether reinforcement strategy would positively influence participation adherence and health in women. Thirty one middle-aged females participating in an aerobic dance class were randomly assigned to three different conditions; feedback (n=10), reward (n=11), or control (n=10). The provide of feedback group was weekly informed of their body fat(%), while participant reward group was announced to win an aerobic dance tights if they miss less than 5 times over an 8 week period meeting 5 times per week. One-way ANOVA showed that the feedback group was higher than the other 2 groups in the number of attendances (p<.05). ANCOVA indicated that the feedback group exhibited statistically greater improvements in the body fat (p<.05) and the total mood disturbance (p<.05) than did the control. The facial skin condition was independently associated with reinforcement. However, repeated t-test showed that the after condition was better than the before condition. It was concluded that provide of feedback is an effective mean in increasing the exercise attendance rate and the health of middle-aged females. The findings were discussed in terms of the importance of increasing exercise adherence and mental health.

일부 임상간호사들의 직무스트레스와 우울과의 관련성

이미옥,류소연,변익건,박정희 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.2

Objective : This study was performed to identify the relationship between job stress and depression of nurses who work at hospitals in Gwangju city. Methods : The data were collected from October 2 to 22, 2003 using the self-administered questionnaire which was composed demographic characteristics, job-related factors, health-related factors, family-related factors, job stress, self-esteem and Korean Beck's depression inventory. The statistic methods were t-test, analysis of variance (ANOVA), Pearson's correlation analysis and multiple regression analysis. Results : 1. The score of job stress of clinical nurses was 169.23 (24.44) , and depression point was 11.37 (7.71). By the depression criteria, the prevalence of depression were 11.2% in pre-depression, 5.7% in moderate and 4.6% in severe depression. 2. It was found that the characteristics that had a statistically significant relation with depression scores were age, marital status, educational background, career, income, drinking status, satisfaction in living and self-esteem. And job stress was statistically significant positive correlation with depression scores. 3. As a result of multiple regression analysis, the job stress had not a statistically significant relation with depression with controlled other related factors. Conclusion : It is necessary to prepare the program about the control and prevention of depression In clinical nurses. Further study need to identify the relationship between depression and job-related factors in nurses working at the hospitals.

위암 환자에서 절제된 림프절 수의 차이와 관련이 있는 인자

정귀애,박정희,변익건,김경종,장정환,김권천,민영돈 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.1

Purpose: By the definition of UICC TNM classification (fifth edition), the nodal stage of gastric cancer is based on the number of metastatic lymph nodes, which is influenced by the number of resected lymph nodes. And individual differences in the number of resected lymph nodes had been observed in patients with gastric cancer. The aim of this study is to verify the factors which are associated with the difference in the number of resected lymph nodes in patients with gastric cancer. Methods: We reviewed 613 patients with gastric cancer who underwent curative resection and D2 lymph node dissection with 15 or more resected lymph nodes. The number of resected lymph nodes was analyzed according to the characteristics of patients, the types of operation and prognostic factors of gastric cancer. Results: The mean number of resected lymph nodes per patient was 33.0 (median: 31.0, range: 15-88). The number of resected lymph nodes was significantly associated with the types of operation, the location and size of tumor, macroscopic types, depth of tumor invasion and the number of metastatic lymph nodes. Patient's age, gender and the histopathological finding's had no relationship with the number of resected lymph nodes. Conclusions: The number of resected lymph nodes from gastric cancer was different in each patient despite of same D2 lymph node dissection and it was associated with several prognostic factors of gastric cancer.

담낭종양에서 CD24의 역할

임성철,이용,김동출,강길,변익건,박정희,최석민 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.2

CD24 is a small heavily glycosylated glycosylphosphatidylinosito-linked cell surface protein, which is expressed in hematologic malignancies as well as in a large variety of solid tumors, It appears to function as a ligand of PUselectin, an adhesion molecule that is present in activated platelets and endothelial cells. The authors aimed to evaluate CD24 protein expression in adenoma and adenocarcinoma of gallbladder to correlate to clinicopathologic data. The staining- was evaluated as stainability (negative, weak-, moderate-, strong-positive) and staining' patterns (membranous vs. intracytoplasmic) for statistical analysis. A highly significant association of cytoplasmic CD24 expression with adenocarcinoma compared to the adenoma of gallbladder was demonstrated. The present study demonstrates that CD24 was abundantly expressed on adenocarcinoma rather than on adenoma, but it was not statistically significant, Interrelation between the stainability or intracytoplasmic staining of CD24 and lymph node metastasis was not statistically significant. The authors conclude that CD24 is involved in tumorigenesis of gallbladder mucosa and intracytoplasmic expression of CD24 is an important molecular marker for malignant transformation.

An Evaluation of the Neonatal Immune System Using a <i>Listeria</i> Infection Model

Byun, Hyun-Jung,Jung, Woon-Won,Lee, Jong-Bae,Chung, Hee Yong,Sul, Donggeun,Kim, Sang Joon,Park, Chung-Gyu,Choi, Inho,Hwang, Kwang Woo,Chun, Taehoon S. Karger AG 2007 NEONATOLOGY Vol.92 No.2

<P><I>Background:</I> T helper 1 (Th1)/T helper 2 (Th2)-biased cytokine regulation may be another reason that neonates are much more susceptible to infectious disease than are adults. <I>Objectives:</I> We attempted to determine the ability of neonatal mice to direct the Th1 phenotype against <I>Listeria monocytogenes</I> (LM), because LM, an intracellular Gram-positive bacterium, induces profound cellular immunity by Th1 cells in vivo. <I>Methods:</I> In order to determine whether neonatal mice evidence strong Th1 activity during LM infection, neonatal mice were compared with adult mice with regard to susceptibility to LM, cytotoxic T lymphocyte activity, and cytokine profiles. Neonatal gene profiles relevant to Th1 and Th2 differentiation during LM infection were also compared between neonatal and adult mice, via real-time PCR and RT-PCR. <I>Results:</I> Neonatal mice were found to be far more susceptible to LM infection than adult mice, due to a lack in the induction of cytotoxic T cell activity, coupled with poor IFN-γ secretion. Further, LM-infected neonatal mice evidenced much lower levels of expression of Th1-type immune components, including IL-12, IFN-γ, Delta-4 and T-bet, as compared to those features in adult mice. These results may be due to the comparably lower expressions of mannose-bind lectins and some of toll-like receptors (TLRs) such as TLR-5, -6 and -9, necessary mediators to develop Th1 immune responses. <I>Conclusions:</I> Neonatal mice may not mount an adequate Th1 type immune response due to a significantly lower expression of Th1-type immune components as compared to adult mice, even when forced into a Th1-prone environment.</P><P>Copyright © 2007 S. Karger AG, Basel</P>