흰쥐 대뇌피질에서의 Cholecystokinin Octapeptide의 分布

황정한,조희중,김은희,박매자,배용철,홍해숙,주강 慶北大學校 醫科大學 1990 慶北醫大誌 Vol.31 No.4

흰쥐 대뇌피질에서 cholecystokinin octapeptide(CCK-8)의 분포를 관찰하기 위하여 간접면역형 광법을 행하여 관찰해 본 결과 다음의 많은 부위에서 CCK-8양성세포 및 양성섬유를 관찰할 수 있었다. 신피질: CCK-8양성세포는 주로 제2, 3층에서, 양성섬유는 제2, 3 그리고 6층에서 저밀도를 나타내었다. 후구: 전후핵에서 많은 CCK-8양성세포 및 양성섬유를 관찰하였다. 이상엽 및 후내야: 양성세포는 주로 제2층에서 관찰되었으며 양성섬유는 제2층에서 중밀도 제3층에서 저밀도로 관찰되었다. 해마체: 많은 양성세포 및 고밀도의 양성섬유가 원추세포층에서 관찰되었다. In order to investigate the distribution of immunoreactive cholecystokinin octapeptide (CCK-8) containing neurons in the cerebral cortex of the rat, brains of the rats were processed for indirect immunofluorescent technique. The results obtained were as follows. Neocortex; CCK-8 immunoreactive cell bodies were found in layer Ⅱ and Ⅲ and immunoreactive axon terminals were heaviest in layers Ⅱ, Ⅲ and Ⅵ. Olfactory bulb; The anterior olfactory nucleus contained numerous CCK-8 immunoreactive cell bodies and a moderate density of immunoreactive axon terminals. Piriform and entorrhinal cortex; CCK-8 immunoreactive neurons and axon terminals were observed in layer Ⅱ and Ⅲ. However, they were more frequent in layer Ⅱ. Hippocampus; CCK-8 immunoreactive cell bodies and axon terminals were found in pyramidal layer.

항암화학요법 종료 시기 암환자의 요구

한경자(Han Kyung Ja),이은옥(Lee Eun Ok),김매자(Kim Mae Ja),박영숙(Park Young Sook),하양숙(Hah Yang Sook),송미순(Song Mi Soon),정재원(Chung Chae Weon),박성희(Park Sung Hee),김보열(Kim Bo Yul) 대한종양간호학회 2005 Asian Oncology Nursing Vol.5 No.2

Purpose: The present study was designed to identify cancer patients' needs when chemotherapy ends. Method: In-depth interview with focus questions was applied for the study. The participants were recruited from the patients receiving cancer chemotherapy in a university hospital. They were seven cancer patients with stomach cancer and two with liver cancer at the ending period of their chemotherapy protocol. Participants were interviewed on discharge date of last treatment and when they returned for the first outpatient follow-up. The focus question was 'what are your needs at this point?' The interviews were audio-taped and transcribed before analysis. The data were analyzed for common categories, special analytic categories, and conceptual categories. Results: Thirty two common categories, ten special analytic categories, and six conceptual categories were identified as patient's needs. The six conceptual categories were comfort needs, social needs, information needs, humanism needs, environmental needs, and self-efficacy needs. Conclusion: There were characteristic specific patients' needs when chemotherapy ends. There are needs to develop and to apply nursing intervention for cancer patients.

항암화학요법 환자의 정보요구 분석

한경자(Han Kyung Ja),이은옥(Lee Eun Ok),김매자(Kim Mae Ja),하양숙(Hah Yang Soak),박영숙(Park Young Soak),송미순(Song Mi Soon),정재원(Chung ChaeWeon),박성희(Park Sunghee),문미혜(Moon Mi Hye) 대한종양간호학회 2004 Asian Oncology Nursing Vol.4 No.2

Purpose: To exarmne Informational needs of cancer patients receiving chemotherapy Methods: A cross<br/> sectional survey design was utilized The sample was 198 cancer patients receiving chemotherapy for a diagnosis of stomach or lung cancer at a university hospital A modified version of Toronto Informational Needs Questionnaire was applied Results Subjects reported highest Informational needs In prognosis dimension. followed by the treatment dimension Including side effects and alternativetherapy Information about medical tests and follow-up care after the treatment was also in great need Dimensions of support for pattents/famlly and sexuahty were low in need The degree of informational needs was negatively correlated with patient's age and number of children Differences were found in informational needs according to the educational level employment status. and gender of the patIents. while diagnosis and treatment options did not make differences in informational needs. Conclusion: Health care professionals need to perceive informational needs of cancer patients receiving chemotherapy. and to provide them with information especially in the area of prognosis and treatment Informational intervention would be effective when it si given with consideration of patien's charactenstics

위 질환의 장상피 화생에 대한 임상적 관찰

김용한(Yong Han Kim),이규섭(Kyu Sup Lee),이기호(Ki Ho Lee),김매자(Mae Ja Kim),권영표(Young Pyo Kwon) 대한소화기학회 1987 대한소화기학회지 Vol.19 No.2

The gastric problems are one of the most serious subjects of internal medicine in Korea. The endoscopic examination of stomach is more valuable than that of radiological means because the biopsy can be performed through fiberoptic gastroscope. In gastroscopic biopsy, the intestinal metaplasia is frequently found. The frequency and location of intestinal metaplasia are examined in this study. The general frequency of intestinal metaplasia is (20.6%) (46 cases) in all (223) biopsied cases. The peak incidence is 31.3% in sixth decade, whereas 13.3% in third decade. 40 cases (87.0%) of intestinal metaplasia is found in gastric antrum. So, we concluded that the intestinal metaplasia is more frequent in aged man and majorities of intestinal metaplasia are found in gastric antrum and 26.1% of the cases are complicated with chronic peptic ulcer.

지역사회 가정간호사업 운영 효과에 관한 연구

박성애,한경자,박영숙,윤순녕,이애주,서문자,박연환,김매자,김금순,하양숙,송미순 서울대학교 간호대학 간호과학 연구소 1998 간호학 논문집 Vol.12 No.1

The purpose of this study was to evaluate the effectiveness of the home care service. The data were collected from the home care service center in the Ckollege of Nursing, Seoul National University, which was operated from September, 1996 to February, 1997. Seven home care nurses were hired and trained for this study. 32 study subjects who were refered from 11 general hospitals 1 public health center in Seoul. Out of 32 subjects, clients with impairment in consciousness and cognition were the most prevalent and the second majority was the clients with malignancies and the third was the client with pulmonary disease. The average number of home visit per week was 2.1 and the average nursing care time was 68 minutes per visit excluding the traveling time. Checking the vital signs and physical examination were the most common nursing activities provided by the home care nurse during home visit, and other activities were specific skilled nursing care, such as urinary catherization, L-tube insertion, exercise and safety care, wound dressing, toileting care and medication. The most used materials during home care were dressing sets, gloves, gauzes, and disinfectants. L-tube, Foley catheter, T-cannular, IV sets were also often used. The most common subjects of health to the clients and their family member education were exercise, safety care and how to manage the stress of family caregiver etc. The effects of home care service were evaluated by the change of client health status, family burden, perceived satisfaction of family member and the quality of life of the client. Health status of the clients who had impairment in consciousness and cognition, peritoneal dialysis, and diabetes were improved. The score of family burden was decreased and the clients were satisfied with home care services considerably. The score of the quality of life was increased but was no statistical significance. As the results of this study, firstly, for saving the traffic expenses and more efficient home care, client assignment to the home care nurse by the geographical-based is needed. Secondly, Referal system with physicians and other health professions should be set up for effective home care. Thirdly, in order to supply nondisposable sterile materials for home care had to be available at any place and accessible to all the residents Fourthly, home care nurse training curriculum, mobility exercise, related nursing and special nursing technique should be strengthened.

Prediction Model for Annual Variation in Total Pollen by Allergenic Trees in Korean Cities

Kim Kyu Rang,Han Mae Ja,Han Young Jong,Lee Yong Hee,Oh Jae-Won 대한천식알레르기학회 2024 Allergy, Asthma & Immunology Research Vol.16 No.1

Purpose: Pollen forecasting systems can provide information for coping with respiratory allergies. They estimate daily pollen production, dispersal, deposition, and removal based on daily weather conditions to predict daily pollen concentrations and provide allergy warnings. As of 2023, the Korea Meteorological Administration (KMA) provides 2-day forecast of allergenic pollens. However, unlike these models, long-term analysis of annual observations of tree pollen reveal annual variations. Therefore, in this study, we aimed to develop annual prediction models for allergenic tree pollens based on long-term multi-site pollen and meteorological data. Methods: Daily pollen concentrations were observed using Hirst-type volumetric spore traps at nine sites in Korea from 1998 to 2021, and daily weather data from the closest KMA stations were utilized. Models were developed to predict the seasonal pollen integral of seven tree species based on monthly mean temperature, wind speed, and total precipitation using three variable selection methods: 1) the t-test based key variable screening followed by linear regression with stepwise procedure (TM), 2) direct linear regression with stepwise procedure from the full variable model (FM), and 3) LASSO regression from the full variable model (LM). Results: Data obtained during 1998–2017 and 2018=2021 were utilized for model development and validation, respectively. The root mean squared error, mean absolute error, mean error, and coefficient of determination (R2) revealed that the TM models were best suited for actual forecasting, even though R2 in the TM model was lower than those of the FM and LM models. Conclusions: The annual variation model in this study can be integrated with the daily pollen forecast model by controlling the annual pollen potential, and the accuracy of the daily forecast can be improved accordingly.

Systematic Significance of Seed Coat Morphology in Silene L. s. str.(Sileneae-Caryophyllaceae) from Korea

Hong, Suk Pyo,Han, Mae Ja,Kim, Ki Joong 한국식물학회 1999 Journal of Plant Biology Vol.42 No.2

Seeds of eight species of Silene s. str. in Korea were examined with a dissecting stereomicroscope and a scanning electron microscope (SEM) to evaluate the systematic significance of seed coat microstructure. The seeds of Silene s. str. were characterized by triangular or reniform shape, planed or concave dorsal surface in outline, tuberculate or colliculate testa, and sinuated cell margin. Based on the degree of grooves and invagination at dorsal surface, the seeds of the examined taxa of Silene s. str. fall into two distinct groups: (Ⅰ) dorsal grooves inconspicuous, surface planed (Silene jenisseensis and S. repens), (Ⅱ) dorsal grooves conspicuous, surface concave (six remaining taxa). Within each group, seeds of all species may be further distinguished based on shape, size, and testa surface sculpturing. A key to the different species or groups of species is provided, and the systematic significance between/among the taxa is also briefly discussed.

Allergenic Pollen Calendar in Korea Based on Probability Distribution Models and Up-to-Date Observations

Ju-Young Shin,Mae Ja Han,Changbum Cho,김규랑,Jong-Chul Ha,오재원 대한천식알레르기학회 2020 Allergy, Asthma & Immunology Research Vol.12 No.2

Purpose: The pollen calendar is the simplest forecasting method for pollen concentrations. As pollen concentrations are liable to seasonal variations due to alterations in climate and land-use, it is necessary to update the pollen calendar using recent data. To attenuate the impact of considerable temporal and spatial variability in pollen concentrations on the pollen calendar, it is essential to employ a new methodology for its creation. Methods: A pollen calendar was produced in Korea using data from recent observations, and a new method for creating the calendar was proposed, considering both risk levels and temporal resolution of pollen concentrations. A probability distribution was used for smoothing concentrations and determining risk levels. Airborne pollen grains were collected between 2007 and 2017 at 8 stations; 13 allergenic pollens, including those of alder, Japanese cedar, birch, hazelnut, oak, elm, pine, ginkgo, chestnut, grasses, ragweed, mugwort and Japanese hop, were identified from the collected grains. Results: The concentrations of each pollen depend on locations and seasons due to large variability in species distribution and their environmental condition. In the descending order of concentration, pine, oak and Japanese hop pollens were found to be the most common in Korea. The pollen concentrations were high in spring and autumn, and those of oak and Japanese hop were probably the most common cause of allergy symptoms in spring and autumn, respectively. High Japanese cedar pollen counts were observed in Jeju, while moderate concentrations were in Jeonju, Gwangju and Busan. Conclusions: A new methodology for the creation of a pollen calendar was developed to attenuate the impact of large temporal and spatial variability in pollen concentrations. This revised calendar should be available to the public and allergic patients to prevent aggravation of pollen allergy.

간호일지와 간호사의 면담자료에 나타난 간호활동 내용의 비교분석

송미순(Song, Misoon),김매자(Kim, Mae-Ja),박영숙(Park, Young Sook),이은옥(Lee, Eun-Ok),하양숙(Hah, Yang-Sook),한경자(Han, Kyung-Ja),류세앙(Ryu, Se-Ang),강혜영(Kang, Hae-Young),김경남(Kim, Kyung-Nam),조문숙(Cho, Moon-Sook) 한국간호과학회 2003 Journal of Korean Academy of Nursing Vol.33 No.6

지역사회중심의 독립형 가정간호 시범사업소 운영체계 개발 및 운영결과 분석

박정호(Park Jung Ho),김매자(Kim Mae Ja),홍경자(Hong Kyung Ja),한경자(Han Kyung Ja),박성애(Park Sung Ae),윤순녕(Yun Soon Nyoung),이인숙(Lee In Sook),조현(Cho Hyun),방경숙(Bang Kyung Sook) 한국간호과학회 2000 Journal of Korean Academy of Nursing Vol.30 No.6