A Case of Urethral Stent for Recurrent Urethral Stricture and Penile Prosthesis for Erectile Dysfunction

Jung, Gyung-Woo,Song, Young-Jin,Park, Young-Ho,Kwon, Heon-Young,Yoon, Jin-Han 동아대학교의과대학 1992 동아의대학술지 Vol.4 No.1

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

정지궤도 위성과 지구국간 광통신 링크의 전송속도 해석

한종석,정진호,김영권,Han, Jong-Seok,Jung, Jin-Ho,Kim, Yung-Kwon 한국전기전자학회 1997 전기전자학회논문지 Vol.1 No.1

정지궤도 위성과 지구국간 광통신을 대기상태와 앙각의 함수로써 해석할 수 있는 한모델(Han's model)을 제시하였다. 한모델에서는 대기상태를 맑은날, 구름낀 날, 안개, 헤이즈, 비, 눈의 여섯가지 전형적인 상태로 구분한다. 비트오류을 $10^{-7}$을 만족하는 데이터 전송속도를 한모델을 이용하여 상향링크와 하향링크에 대해 해석하였다. 상향링크시의 포인팅손실이 하향링크시의 대기에 의한 공간 가간섭 저하보다 크기 때문에 데이터 전송속도는 하향링크 보다 오히려 상향링크시에 제한됨을 알 수 있었다. Han's model, which is able to analyze optical communication between earth station and geo-satellite as a function of atmospheric conditions and elevation angles. is presented. In Han's model, atmospheric conditions are roughly classified into six basic types; clear sky, cloud, haze, fog, rain and snow. Data rate satisfying for the BER below $10^{-7}$ is analyzed by Han's model in case of up-link and down-link, respectively. Data rate is more limited by up-link than by down-link because the pointing loss caused by atmosphere on the up-link is greater than the spatial coherence degradation caused by atmosphere on the down-link.

Estimated incidence of juvenile-onset recurrent respiratory papillomatosis in Korea

Jin-Kyoung Oh,Hwa Young Choi,Minji Han1,Yuh-Seog Jung,Sang Joon Lee,Moran Ki 한국역학회 2021 Epidemiology and Health Vol.43 No.-

OBJECTIVES: Recurrent respiratory papillomatosis (RRP) is caused by human papillomavirus (HPV) types 6 and 11 and is potentially preventable through vaccination. This study estimated the incidence of juvenile-onset RRP before the implementation of the national HPV vaccination program in Korea. METHODS: We conducted a cohort study using claims data provided by a mandatory insurance program to estimate the incidence of RRP and associated healthcare use. Patients with juvenile RRP were defined as those aged ≤12 years with ≥2 admissions or ≥2 outpatient visits during which they received the International Classification of Diseases, 10th revision code for benign neoplasms of the larynx (D14.1). RESULTS: During 2002-2014, 123 children (74 boys and 49 girls) were diagnosed with RRP. The patients had a mean of 6.5 person-years of follow-up. The incidence was estimated at 0.30/100,000 person-years. The median age at diagnosis was 4.0 years (mean, 4.3). Thirty-six (29.3%) patients underwent surgery, including 23 patients (18.7%) who underwent 2 or more surgical procedures. Severe disease, measured by more frequent surgical procedures and shorter time intervals between consecutive operations, was associated with a younger age at diagnosis. CONCLUSIONS: The estimated incidence of juvenile-onset RRP in Korea was similar to that reported in other countries. The RRP burden should continue to be monitored using National Health Insurance Service claims data.

요추부의 Transpedicular Screw를 이용한 수술의 합병증

정진명,한종우 대한신경외과학회 1991 Journal of Korean neurosurgical society Vol.20 No.12

46 consecutive patients underwent application of transpedicular screw since June 1988, and had follow-up at least for 6 months. 15 cases(32.6%) of them had one or two complications. There were 5 wound infections, which seemed to be caused by long operation time, wide metal implant area and personal predisposing factors. There were 5 patients with screw breakage. The exact screw alignment and avoidance of vigorous distraction are considered to by important in minimizing screw breakage. 2 patients had screw loosening, which could be reduced by proper placing of screw and methy1 metacrylate enforcement. Nerve root irritation and adjacent disc space degenerative change were developed in 5 cases. Discspace changes were induced by stress transfer after rigid fixation. Finally, postoperative severe wound pain which persisted for a long time was another troublesome problem.

백서 중대뇌 동맥의 폐쇄에 따른 경색의 시간적 변화

정진명,정영섭,박인성,이상형,김현집,최길수,한대희 대한신경외과학회 1993 Journal of Korean neurosurgical society Vol.22 No.3

For the assessment of clinical management, for the confirmation of clinical findings, and also for the evaluation of new diagnostic techniques to determine the location as well as the extent of area of infarction on evolution in cerebral tissue is essential. Sequential evolution of infarction in 2% 2, 3, 5-triphenyltetrazolium hydrochloride(TTC) staining and its concomitant neurological changes were investigated in the rat following left middle cerebral artery occlusion(MCAO). In addition, the pathological evaluation was performed in the same coronal cut slice of each TTC staining. The results were : 1) In the TTC staining method, the cerebral infarction was not found in the 2 hour group rats, and appeared as white or pink color after 4 hours. 2) The size of infarction was significantly correlated with time of occlusion before sacrifice(p<0.05). The size increment was most obvious between 8 hour and 24 hour groups. 3) The time evolution of cerebral infarction was most prominent in the cerebral cortex, and was minimal in the basal ganglia which are supplied by the 'end artery'. 4) The cerebral infarction appeared first in the coronal cuts at the 4, 6, and 8㎜ from the frontal pole, which is the main territory of MCA. 5) The cerebral infarction, mainly presented in the 4, 6, and 8㎜ coronal cuts from the frontal pole, extended from the pyriform cortex to the fronto-parietal cortex. It also appeared at 2, 10㎜ coronal cuts from the frontal pole in 24 hour group. 6) The neurologic sign was not correlated to the time of MCAO and the size of infarction on evolution. Therefore, the prediction of location and size of area of infarction on evolution was impossible by the neurological status. 7) The histopathological change was detected as early as in 2 hours. However, hematoxylin and eosin(H & E) stained sections showed only subtle changes, such as small irregular areas of cortical spongiosis and neuronal shrinkage up to 8 hours. There was no significant difference between lesion areas of 2 hour and 8 hour groups. The pathological findings of 24 hour group rats was definite and appeared as a central area of coagulation necrosis and rare faction surrounded by a zone of peripheral spongiosis.

江原道內 造景植物의 利用과 有用自生植物에 관한 硏究

정진형,이기의,한재오 강원대학교 조형예술연구소 2005 조형예술논문집 Vol.6 No.-

This study was executed to find out how to improve the planting and use of landscaping plants in Kangwon-Do by surveying the planting, gardens, parks, schools, etc. and the main mountains in this province to select available native plants. The result are as follows: 1. Forty-four tree species and 41 flower species were counted at 703 schools in Kangwon-Do. The major species of school trees were Juniperus chinensis, Pinus densiflora, Abies holophylla, Ginkgo biloba, Pinus koraiensis, Taxus cuspidata, Zelkova serrata, and Pinus thunbergii. The ratio of native species to exotic was 35:9. The major species of school flowers were Rosa centifolia, Forsythia koreana, Zinnia elegans, Rhododendron mucronulatum, Chrysanthemum morifolium, and Rosa rugosa. The ratio of native species to exotic was 21:20. 2. Twelve flower species and 7 tree species were designated in 18 City and Keun. The species of flowers that ,presented high designation frequency were Rhododendron schlippenbachii, Forsythia koreana, Magnolia sieboldii, and Prunus armeniaca var. ansu, the trees that presented high designation frequency were Ginkgo biloba, Pinus koraiensis, and Taxus cuspidata. 3. Eighty-seven woody plants species were planted in 2003 and 2004 in the Young Seo district (the southern area of Kangwon-Do), the ratio of native species to exotic was 56:31. The major species of woody plants were Pinus densiflora, Prunus yedoensis, Prunus sargentii, Cornus officinalis, Pyrus pyrifolia, Rhododendron yedoense var. poukhanense, Pinus koraiensis, Taxus cuspidata, Hibiscus syriacus, Forsythia koreana, Zelkova serrata, Acer triflorum, Rhododendron obutusum, and Ligustrum obtusifolium. A total of 620,000 plants were planted. 3. Eighty-seven woody plants species were planted in 2003 and 2004 in the Young Seo district (the southern area of Kangwon-Do), the ratio of native species to exotic was 56:31. The major species of woody plants were Pinus densiflora, Prunus yedoensis, Prunus sargentii, Cornus officinalis, Pyrus pyrifolia, Rhododendron yedoense var. poukhanense, Pinus koraiensis, Taxus cuspidata, Hibiscus syriacus, Forsythia koreana, Zelkova serrata, Acer triflorum, Rhododendron obutusum, and Ligustrum obtusifolium. A total of 620,000 plants were planted. 4. Eighty-three woody plants species were planted recently in Youngdong district (the eastern area of Kangwon-Do), the ratio of native species to exotic was 53:30. The major species were Pinus thunbergii, Rhododendron lateritium, Rhododendron schlippenenbachii, Hibiscus syriacus, Prunus yedoensis, Pinus densiflora, Syringa dilatata, Rhododendron yedoense var., Poukhanense, Rosa rugosa, Prunus sargentii, Rosa centifolia, Juniperus chinensis, Euonymus japonica, Forsythia koreana, Chionanthus retusus, Acer palmatum, and Chaenomeles sinensis. 5. Through these results, it was thought that a diversification of plant species, including a selection of plants suitable to each space and the general use of native species were needed. So 254 plants native to Kangwon-Do were presented to correspond to these requirements. The especially valuable wild plants were Chionanthus retusus, Acer mandshuricum, Acer tegmentosum, Celtis sinensis, Malus baccata, Syringa wolfi, Cornus controversa, Styrax japonica, Styrax obassia, Sorbus commixta, Deutzia coreana, Viburnum carlesii, Sambucus williamsii var. coreana, Philadelphus schrenckii, Echinosophora koreensis, Exochorda serratifolia, Spiraea trichocarpa, Symplocos chinensis for. Pilosa, Rhododendron brachycarpum, Rhododendron micranthum, Rosa davurica, Rhododendron mucronulatum for. albiflorum, Actinidia spp., Akebia quinata, Vitis amurensis, Aster koraiensis, Chrysanthemum boreale, Chrysanthemum zawadskii var. latilobum, Dianthus sinensis, Heloniopsis orientalis, Hosta lancifolia, Hylomecon vernale, Leontopodium coreanum, Lilium spp., Aceriphyllum rossii, Paeonia obovata, Patrinia saniculaefolia, Primula sieboldi, Convallaria keiskei, Sedum kamtschaticum, and Saxifraga fortunei var. incisolobata.

태권도 경기규칙 제정기 이전의 겨루기에 대한 고찰

진중의,박종창,한창효 용인대학교 무도연구소 2000 武道硏究所誌 Vol.11 No.1

Before 1962 Taekwondo was not a sport that concerned the protection and care of the players, the role of judges, and the understanding of the spectators. At that period, Taekwondo's playing rules varied with each gymnasium that provided sporting grounds. Taekwondo matches were held in gymnasiums; no protective gear was provided or in use. A match persisted until one of the players was quelled; a single round was played. Different morals and rules were practiced in each gymnasium according to their founders. The "Leader" department held more contests than any other type of gym. They were held both indoors and outdoors. In the "Blue" department, a procedure was followed; therefore, 80% of the training course had to do with the basic behavior and formal forms of Taekwondo. 20% of the procedure were contests, which were held after the end of the training. Training of the spirit was also undergone to emphasize the spirit of martial arts. Each gym had its own training methords and programs.

한국인 만성 간 질환 환자에서 G형 간염 바이러스 감염의 유병률에 대한 연구

이진호,이한주,윤정환,이효석,김정룡 大韓消化器病學會 1998 大韓消化器病學會誌 Vol.31 No.3

Heavily T2-weighted Fast Spin Echo 기법을 이용한 자기공명 요로조영술의 임상적 고찰

한재진,김정삼 광주보건대학 1997 論文集 Vol.22 No.-

The purpose of this study was to evaluate the utility of the MR urography in patient with ureterohydronephrosis. Twenty-five patients with ureterohydronephrosis were researched by 1.5T superconducting unit with body coil. The causes of dilation were the follows: Ureteral benign stricture (n=10), ureteral stone (n=7), ureteral malignant stricture (n=6), and uretero-vesical reflux. (n=2). Coronal images were obtained by using a fat suppressed, respiratory-triggered, heavily T2-weighted fast spin echo sequences, and the images were processed by using a maximum intensity projection algorithm, We evaluated the technical success rate, the level and the cause of the obstruction. In 100%(25/25): of cases, MRU could be obtained successfully. The accuracy of MRU in the determining the level of the obstruction was 100%(25/25). The accuracy of the chagnosis of obstruction was 92%(23/25). MRU may be an effective chagnosis method for evaluating the ureterohydronephrosis without exposure of radiation or risks associated with lodinated contrast material. MRU may be alternative to IVU in patient with hydronephrosis.