동일한 시료에 대한 국내 기관간의 STR 분석결과 비교 : STR 유전자좌 분석법의 표준화 설정을 위하여

박종태,신경진,양윤석,우광만,이숭덕,이승환,이정빈,정연보,조승희,한길로,한면수,홍승범 大韓法醫學會 2001 대한법의학회지 Vol.25 No.1

This paper described a collaborative exercise intended to see what kinds of short tandem repeat (STR) loci are used in different DNA typing laboratories in Korea and to compare their results for the demonstration whether uniformity of DNA profiling results from different laboratory could be achieved in Korea Laboratories were asked to test five tissue DNAs using methods routinely used in each laboratory and to report the results to the coordinating laboratory. The exercise demonstrated that each laboratory was using different STR loci for the typing with different STR numbers,2 VNTRS,36 STRs and amelogenin in total, and the direct comparison of the results from all the laboratory for the 18 loci could not be done as only one laboratory submitted typing results. Among 21 loci for which several laboratories submitted typing results, results for 14 loci were the same and results for the other 7 loci were different depending on the participating laboratory. D1S80, F13A01, D16S539, D21S11, D18S51, D3S1744 were the loci with different typing results. Even in the cases where commercial kits were used, the results were not the same depending on the machines used, that is the capillary electrophoresis or the gel based electrophoresis. The reason for the different results, points about the standardization of the methods arid the profiling data were described.

니트섬유강화 복합재료의 기계적 성질에 관한 연구

한길영,이동기,최병기,오환교,신용욱,전수영 조선대학교 에너지.자원신기술연구소 1999 에너지·자원신기술연구소 논문지 Vol.21 No.2

Using conventional textile techniques such as weaving, braiding, knitting and stitching it is possible to produce a wide range two and three dimensional fiber preforms. However, so far only a limited attention has been given to knitted fabrics in composite industry. This is mainly due to the opinion that knitted fabric reinforced composites posses low mechanical properties owing to their looped fiber architecture. But it is possible to obtain desired mechanical properties by selecting proper knitted fabric structure. In this paper, tensile failure load and displacement of one yarn, four yarns and knitted fabrics of ten yarns of kevlar fiber were determined experimentally in the unidirection. Mechanical properties of plain weft knitted fabrics reinforced composite intrusion beam for car side door application were investigated experimentally, which compared with desire value of American Fedral Motor vehicles Safety Standard (FMVSS) and presented the results.

Ellipticine과 그 이성질체들에 대한 분자궤도함수론적 연구

한성욱,이길준,김복조 경운대학교 산업기술연구소 2002 産業技術硏究論文誌 Vol.5 No.1(B)

Molecular orbital studies were carried out for the ellipticine and its isomers, known as having antitumor activity and cytotocity, by semiemperical PM3. Electrostatic potential studies have shown that the most reactive site of proton attacks was the nitrogen atom in carbazol ring. The net charge of the nitrogen was linearly correlated with the basicity of the isomers. We have predict the antitumor activity of the isomer by the basis of the dipole moment [suggested by Barone et.al. J. Mole. Stru.(Theochem) (1992), 253, 319]. And we have suggested that frontier orbital theory is valuable to explain for the formation of covalent adducts. These results may suggest clues that the method how to interpretate the mechanism of action for ellipticine and how to design new drugs.

도시하천의 환경 친화적 개선방안에 관한 조사연구

이길영,권득용,김영안,한천규 대전대학교 산업기술연구소 1999 산업기술연구소 論文集 Vol.10 No.1

The three main steams flowing through Taejon have some serious problems to be solved or improved. They are : First, the uniform cross section of the rivers should be changed. Second, the extension of the riverside road should be reconsidered. Third. the neighborhood parks on the flood plain should be modified. Fourth, the flood plain parking place must not be constructed. Fifth, the ecosystem will be destroyed by the structure constructed along the rivers. In this study, we suggest that the investment and research on the development of the new technology for the setting the rivers in natural condition should be needed now and the continuous investigation and long-term plan to preserve the ecosystem of the rivers should be required. The environmental conditions of Taejon-stream, Yudung-stream and Kap-stream are indicators of the standard of living of the citizens in Taejon. Now is the time to reconsider the careless construction around the rivers and to prepare the long-term plan for the protection of the ecosystem and natural environment.

콘크리트 구조물용 GFRP리바의 기계적 특성에 관한 연구

한길영,이동기,김성용,전상기,최종대,박준식 조선대학교 에너지.자원신기술연구소 2000 에너지·자원신기술연구소 논문지 Vol.22 No.2

In this paper was studied on the mechanical characteristics of Glass Fiber Reinforced Plastics(GFRP) of the steel bar it is to replace The advantage of FRP such as high strength low weight and chemical inertness or noncorrosiveness can be fully exploited. GFRP bar were successfully fabricated at 10mm nominal diameters and hollow types using a pultrusion method Tensile and bending specimens from this bar were tested and compared with behavior of GFRP rebar and steel bar.

Dioxin류의 반응에 대한 분자궤도함수론적 연구 : dibenzo-p-dioxin, 2,7-dichlorodibenzo-p-dioxin, dibenzofuran, 2,8-dichlorodibenzofuran 중심으로

한성욱,이길준,김복조 경운대학교 산업기술연구소 2001 産業技術硏究論文誌 Vol.3 No.2(B)

Molecular orbital studies for dibenzo-p-dioxin, 2,7-dichlorodibenzo-p-dioxin, dibenzofuran and 2,8-dichlorodibenzofuran were carried out by semiempirical PM3 method. Reaction sites for nucleophilic, electrophilic and radical reaction of dioxins were predicted and discussed by MO studies. The values of approximated superdelocalizability were 0.7802, 0.2686, 0.3104, 0.1982 for the above dioxins, respectively. And reported rate constant for the reaction of dioxins with OH radical (Eitzer et. al.. Environ, Sci. Technol. 1989, 23, 1389) was well correlated with approximated superdelocalizability.

자동차용 시로코팬의 유동특성에 관한 연구

이행남,박길문,이덕구,정한별,김건일,설재림 朝鮮大學校 機械技術硏究所 2005 機械技術硏究 Vol.8 No.1

The sirocco fan is used to get low noise, and it has been applied to a lot of industry field like the heat engine, the fluid instrument power plant, the food industry, environment industry etc... because there are not problems even it is mixed with a any kind of liquid, gas, and solid. The flow characteristics in sirocco fan are investigated by PIV. The experiment using PIV measurement for Test section's flow characteristics acquired velocity distribution, Condition : when sirocco fan in automobile air controller maximum 1450RPM, and a revolution is a variation (l)950RPM, (2)l100RPM, (3) 1250RPM. The agreement a experiment shows the validity of this study and the results of this study would be useful to the engineers who design for the flow systems

폐흡충에 의한 무균성 노흉에 대한 돼지꼬리형 도관(pig-tail catheter)을 이용한 치료의 효과

한경택,권세훈,김형호,하재화,선길홍,권용은,윤성호,이승일 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.3

Background: Pulmonary paragonimiasis is caused by consumption of raw or improperlycooked crustacea infected with the laval stage (metacercaria) of Paragonimus westermani. The most characteristic symptoms were rust-colored sputum and cough. Paragonimiasis causes pleural thickening or effusion in 48% of the patients. Pleuro-pulmonary paragonimiasis can be easily overlooked by physicians who do not suspect this disease in the differential diagnosis. Method: We compared the outcomes of 11 patients with paragonimus empyema managed either through thoracotomy or pig-tail catheter drain. These patients were confirmed by food history, clinical and radiological findings, and laboratory data. Results: The male and female ratio was 1.75 : 1, and mean age was 40.0 ± 13.5 years. AII patients had pulmonary symptoms such as cough or chest pain. Serum-ELISA for paragonimiasis were all positive (mean titer was 0.57). AII patients had pleural effusion in radiological findings( 2 patients had bilateral pleural effusion). All patients received praziquantel (75 ㎎/㎏/day for 3days). Two patients were treated with thoracotomy and nine patients were treated with pig-tail drain. Hospital stay were 14.5 days in thoracotomy group and 5.6 days in pig-tail group respectively, Conclusion: Compared to the conventional thoracotomy grouP, the patients with paragonimus empyema who received pig-tail catheters had a significantly-decreased period of drain in situ, were clinically improved earlier, and were discharged earlier.

STR 유전자의 개인식별력 측정을 위한 통계량

이혜승,이재원,한길로,황적준 大韓法醫學會 1998 대한법의학회지 Vol.22 No.2

When we intend to do the personal identification using DNA profiles, it will obviously be better to use as much information as possible. The power of identification is increased by using the genetic marker system such as VNTRs or STRs. Although STRs do not have many alleles per locus as VNTRs, these can be compensated by a large number of loci that are potentially usable. However, it will be more efficient to use a morphic loci. Therefore, prior to choose the genetic marker system of STRs for identification, it is essential to consider the statistical parameters of each STR locus, such as obs-H(observed heterozygosity), exp-H(expected heterozygosity), pM(probability of match), DI(discrimination index), PD(power of discrimination), MEC(mean exclusion chance), MEP(mean exclusion paternity), PIC(polymorphic information content) et al. In this article, we described the exact meaning of statistical parameters for the purpose of identification.

금강하구 해양퇴적에 관한 연구

이길영,지윤식,한천규 대전대학교 산업기술연구소 2000 산업기술연구소 論文集 Vol.11 No.1

In this study, we discussed littroal movement and sedimentation of Keum-river estuary and estmated of deposition capacity. Keum-river estuary sea wall was constructed in 1988 Jan. and the sluice gate was completely closed in 1995 May. At the present, Kun-Jang new port. South and North jetty, Semankume sea wall and Kun-Jang industry estate are developing the Kume-river estuary around. At this developing and construction of Keum-river estaury, in many element of hydrauli - ocean waves, tide, tidal prism and depth of water - have changed. Tide analysis used statistics-analysis and harmonic-analysis from 1984 to 1997. Depth of water analysis used bathymetric chart from 1985 to 1997. Therefore we must correctly decise hydraulic element that is use simulation numerical test and hydraulic model. We analyze ocean waves, tide, tidal prism and depth of water change and modeling bed-load movement simulation; K-Cytengel, suspending-load deposition simulation; DIMOS-IV. Through the K-Cytengel and DIMOS-IV simulation estemated the sedimentation capacity and propose suitable answering such as dredging, water injection and remove of estuary sea wall.