건강식품 바이탈 및 비지놀의 抗疲勞 效果에 관한 연구

정경수,김혜경,김희수,김계양,곽영숙,김학범 충남대학교 약학대학 의약품개발연구소 1993 藥學論文集 Vol.9 No.-

As a result of extensive research efforts on the oriental medicinal herbs, some of their interesting biological activities have been elucidated. In the present study, antifatigue effects of two natural food supplements consisting of oriental herbs, Vital and Vigilor, were investigated using the ICR mice. The mice were fed with antibiotic-free normal mouse feed containing Vital or Vigilor for 14,28, or 31 days and then subjected to forced swim tests. In a test carried out in melting-ice water, Vital and Vigilor significantly increased the exhaustion times of the 28 day-fed mice by 26.9 % (p < 0.01) and 16.2% (p < 0.05), respectively. However, in the other test performed at 15±0.5℃ using 31 day-fed mice, Vigilor failed to increase the exhaustion time significantly (at p< 0.05), while Vital showed antifatigue effect by increasing the swimming time by 29.9% (p<0.01). Neither of Vital nor Vigilor exerted antifatigue effects in a swim test carried out on day 14 after the initiation of feeding. These results suggest that Vital and Vigilor exhert antifatigue effets when administered for a sufficient period of time by enhancing the health of the host animals.

제 2형 당뇨병 환자에서 혈중 Metalliproteinase-9의 농도

김상용,김희중,주유철,최동현,배학연 조선대학교 2000 The Medical Journal of Chosun University Vol.25 No.2

Purpose : Diabetic nephropathy is a serious complication of diabetes and accounts for much of its morbidity and mortality. It is well known that the overt clinical phase of diabetic nephropathy is preceded for many years by the presence of microalbuminuria. Microalbuminuria is thought to be a marker of widespread vascular damage and may underlie the propensity toward severe extrarenal vascular disease in microalbuminuric patients. Metalloproteinase-9 has a broad substrate specificity for native collagens as well as proteoglycan and elastin. One study reported that an increased plasma metalloproteinase-9 concentration precedes the development of microalbuminuria in type 2 diabetic patients. Another study reported that a high glucose concentration cause a abnormality on the activity of metalloproteinase by the mesangeal cell. The purpose of the present study was to examine whether palsma metalloproteinase-9 concentrations are altered at various complications in type 2 diabetic patients. Methods : Sixty patients with type 2 diabetes and thirty healthy control were recruited for the present study. No patient had any malignancy or history of heart disease, liver disease, collagen disease. We recorded age, duration of diabetes, and blood pressure. After an overnight fast, blood was drawn from an antecubita1 vein of measurement of glucose, metalloproteinase-9, HbA1C, and serum creatinine. To measure plasma concentration of metalloproteinase-9, a one step sandwich enzyme immunoassay using two monoclonal antibodies was used. Patients were divided into two group according to the presence or abscence of microalbuminuria. The groups were then compared with regard to clinical and laboratory characteristics and serum concentration of metalloproteinase-9. Results : The mean serum levels of metalloproteinase-9 in diabetic patients (62.32±25.83ng/㎖) were significantly higher than in healthy controls(12.92±4.97ng/㎖) (p<01). The mean serum levels of metalloproteinase-9 in diabetic patients with microalbuminuria(81.16±41.43ng/㎖) were significantly higher than in those with normoalbuminuria(31.48±7.34ng/㎖) (p<01) and much more than in healthy control(12.92±4.97ng/㎖) (p<05). Furthermore, the severity of nephropathy were closely associated with the serum metalloproteinase-9 level and the serum metalloproteinase-9 level was significantly correlated with microalbuminuria. The mean serum level of metalloproteinase-9 in diabetic patients with retinopathy(61.74±39.07ng/㎖) was significantly higher than in those with no retinopathy(34.98±9.02ng/㎖) (p<05). But, in diabetic patients with normoalbuminuria, there is no difference between the groups with retinopathy versus no retinopathy. Conclusion : In summary, a sustained increase in serum metalloproteinase-9 in patients with type 2 diabetes is associated with a high risk for the development of microalbuminuria. The results of this study suggest that the serum rnetalloproteinase-9 was a useful and noninvasive marker for the development of diabetic nephropathy. It could be also used to predict the development of diabetic complications and to assess therapeutics or the prognosis of diabetes. The usefulness of this model will be clarified by a larger scale and serial study.

물리적 활성화에 의한 coffee char의 제조

김학희 선문대학교 첨단과학기술연구소 1999 첨단과학기술연구소 논문집 Vol.4 No.-

하이퍼-프리젠테이션 개념은 하이퍼-미디어 개념을 확장한 것으로, 동적으로 연출되고 있는 상황에서 링크개념을 설정하여 특정시점이나 지점에서 원하는 다음 정보를 보기 위해서 비순차적으로 연출할 수 있도록 하는 연출이다. 이러한 비순차적인 연출방법인 하이퍼-프리젠테이션 개념을 도입함으로써, 자유로운 멀티미디어 연출이 가능하게 되었지만, 이러한 동기화 방법에 의해서 혼합된 여러 프레젠테이션들간에는 일관성 문제가 발생할 수 있다. 본 논문에서는 하이퍼-프리젠테이션 명시 프로그램의 일관성 검증을 위해서 Petri Net을 이용한 하이퍼-프리젠테이션 명시 방법을 제시하고, 그것을 이용한 명시 프로그램의 일관성을 검증하는 방법을 제안한다. The concept of a hyperpresentation, as an extension of a hypermedia, is the presentation in which time-varying multimedia presentations are dynamically linked together and a hyperlink's context can be changed over time at any time during a continuous presentation. While this concept provides users with a flexible and powerful tool for their descriptions of the multimedia presentation, inconsistency problems in the synchronized presentations connected by hyper links can be introduced. This paper introduces a method of describing the hyperpresentation using Petri Net and proposes a methods of detecting inconsistent hyper link loop in the hyperpresentation description.

세라믹필터 역세정에 노즐 및 디퓨저 형상이 미치는 영향

김학빈,정재화,조형희 연세대학교 산업기술연구소 2001 논문집 Vol.33 No.1

The present study has been conducted experimentally to optimize the nozzle and diffuser shapes and diameters for dust removal system. Investigation of a dust removal system has been carried out to develop hot gas clean-up technology and to study for feasibility of clean coal technology pilot plant construction. Experiments was conducted to investigate the effects of pulse nozz1e and diffuser shapes on the air entrainments and on the pressure distribution in a particulate removal system. The main experimental parameters are different nozz1e shapes, nozzle diameters and nozzle tip positions from the diffuser upper plane. Especially, two different types of diffusers with a convergent-divergent shape and a divergent shape were tested systematically. Key words : IGCC(석탄가스화 복합발전), Ceramic Candle Filter(세라믹 캔들 필터), Reverse Cleaning(역세정). Nozz1e(노즐), Diffuser(디퓨저), Entrainment Ratio(동반류비)

現職敎師와 敎員養成所 受講生의 敎職態度에 關한 比較硏究

金學守,李熙道 慶北大學校 師範大學 1971 敎育硏究誌 Vol.13 No.-

Teachers' attitudes about the teaching profession, their personalities, and their teaching behaviors influence their students. This study was undertaken to investigate how teachers and the attendants at teachers training courses (ATC) differed in the attitudes about the teaching profession; Why did they enter the teaching profession, or why did they choose the teaching profession? How do they think of receiving the honor due to their profession? How much do they satisfy with the teaching profession? How long will they remain in the teaching profession? How do they think of the teachers training course? and How do they think of the ideal teacher's personality? The subjects were 385 elementary school teachers, 304 secondary school teachers, 350 attendants at teachers training courses for elementary school (ATCE), and 270 attendants for secondary school. (ATCS). The main findings of present study were as follows: 1. The main differences in the reasons why to choose the teaching profession between school teachers and ATC are that the elementary school teachers emphasize the value of esteem, while ATCE emphasize the value of social service. And ATCS emphasize the value of time to spare, whereas the secondary school teachers do not. 2. The teachers perceive they do not receive the honor due to their profession both socially and economically, whereas ATC ththink teachers are treated well. But the teachers and ATC agree that teachers are treated well from their students. 3. The teachers are unsatisfying with their teaching profession and few teachers are satisfying, while ATCS are very much satisfying to choose the teaching profession. In accordance with the above results, many teachers want to leave their teaching professsion more than ATC. 4. Both the teachers and ATC think that teachers must receive regular teachers training courses as well as educational practices. 5. The elementary school teachers think of the ideal teacher as more flexible and extraverted than ATCE, whereas ATCE as more pleasant, intelligent, cheerful than the teachers. The secondary school teachers think of the ideal teacher as more rigid, intelligent and aggressive than ATCS. 6. While the teachers would much more emphasize patriotic as the ideal teacher's characteristics, both ATCE and ATCS almost ignore it.

Oriental계 백합의 종구생산에 있어 재배지역 및 정식기가 생육 및 구근비대에 미치는 영향

김학기,이상철,선선영,전승희 강릉대학교 동해안지역연구소 2000 東海岸硏究 Vol.11 No.1

This study was conducted to investigate effects of cultivation area and planting time on bulb growth and enlargement of Lilium oriental hybrids in seed buld production. Planting time was divided into three periods such as May 15, 30, June 15 and Cultivation areas were alpine Daegwallyong and low land Kangnung area. The results were as follows: 1.The temperature of Daegwallyong from June to September was around 16-18℃ which was the optimum temperature for growth of Lilium oriental hybrids compared with above 20℃ of Kangnung area. 2.The bulb emergence rate in Kangnung area was 1-3 days faster than Daegwallyong. As the planting time was delayed, the bulb emergence rate was faster. 3.There was no significant difference in plant height between cultivation area and cultivars, but as the planting time was delayed, the plant height in Kangnung was much longer than Daegwallyong. 4.The chlorophyll content was high in the early planting time and that in Daegwallyong was higher than Kangnung. 5.The fresh and dry weight of leave was increased in Daegwallyong cultivation, compared with Kangnung. 6.The growth of underground parts such as numbers and length of basic roots and root system of stem roots in Daegwallyong was much better than Kangnung. 7.Virus infection rate in Daegwallyong was lower than Kangnung, but in the phytophthora blight and leaf blight vice versa. 8.The faster the planting time was, the higher the bulb weight was. And the bulb weight in Daegwallyong was 93% higher than Kangnung.

韓國産 穀物에서의 trichothecene mycotoxin 生成에 關한 硏究

김학성,민봉희 대구대학교 기초과학연구소 1988 基礎科學硏究 Vol.5 No.-

This study was carried out to investigate the trichothecene mycotoxin productivity of Fusarium tricinctum NRRL 3229. F. tricinctum was cultured on cereal grains at temperature from 10℃ to 15℃ for 4 weeks. Toxins were extracted with solvent and purified partially by column chromatography. The amounts of T-2 toxin, HT-2 toxin, diacetoxyscirpenol and T-2 tetraol were quantitated by gas-liquid chromatography. Corn and millet had the highest productivity of trochothecene mycotoxin. The highest levels of T-2 toxin and HT-2 toxin were produced on corn and maximal yield of T-2 tetraol was obtained in cultures on millet. However, no detectable amount of diacetoxyscirpenol was observed in this experiment. Metabolism of T-2 toxins showed high differences among cereal grains. T-2 toxin was metabolized easily into HT-2 toxin in corn, polished rice, glutinous rice, and sorghum and metabolized very slowly into T-2 tetraol toxin. However, T-2 toxin in unpolished rice was metabolized into HT-2 toxin and T-2 tetraol. Also, T-2 toxin was metabolized rapidly into HT-2 toxin and T-2 tetraol in barley, wheat, millet and red bean while T-2 toxin in unpolished rice was metabolized very slowly into HT-2 toxin and T-2 tetraol.

각종 경화제 처리가 백합의 줄기 경도에 미치는 영향

김상수,원재희,안수용,김학기 강릉대학교 동해안지역연구소 2000 東海岸硏究 Vol.11 No.2

This experiment was carried out to investigate the effect of hardening materials, which were silicate complex fertilizer for the basal fertilization which contained 25percent SiO2, 45percent Ca, and 2percent Mg, Calcabon wettable powder for the foliar spray which contained 95percent calcite and 5percent surfactant, and Neo-Cal for the forliar spray which contained 17percent chelate calcium, to strengthen the stem hardness on lily(Lilium spp. 'Con Amore'). Among the treatments, the growth of the treatment of basal fertilizer on silicate complex was better than that of the other treatments. On the shear test of stem hardness, the hardness on the treatment of basal fertilizer on silicate complex was higher than that on the other treatments and the control was the lowest. And on the puncture test of stem hardness, the pattern among the treatments was He same on the shear strength. Mineral contents of leaf were higher than those of stem, and the contents of Ca and Si on the treatment of basal fertilizer on silicate complex were 1.07percent and 1.25percent, respectively, and these contents were higher than those of the other treatments.

TKR와 TSR·TCR간 연계추진에 관한 복합운송업체의 인식분석

김경희,이학승 한국물류학회 2004 물류학회지 Vol.14 No.3

동북아지역을 관통하는 철도운송에 대한 관심이 2000년 6월 남북정상회담을 통한 9월 경의선 복원공사 착공으로 가시화되기 시작하였다. 이들 동북아지역은 러시아, 중국, 한반도, 그리고 일본 등과 서로 밀접한 관계를 맺고 있으며, 한반도는 이들 국가들의 한 가운데 위치하고 있으면서 동북아지역의 징검다리 역할을 하고 있다. 또한 동북아지역에 대한 관심이 고조되는 가운데, 이들을 연결하는 한반도종단철도(TKR)를 비롯한 대륙횡단철도인 중국횡단철도(TCR)과 시베리아횡단철도(TSR)에 대한 연구들이 활발히 진행되고 있는 실정이다. 따라서 본연구에서는 TSR과 TCR에 대한 최근 현황 및 문제점에 대해 살펴보고,TKR의 연계추진과정을 알아보고자 한다. 그리고 현재 수도권에 집중하여 영업망을 가진 복합운송업체들의 대상으로 설문조사를 통해 대륙철도운송에 대한 인식 파악과 향후 이들 업체들의 인식 개선 방안에 대해 논의하고자 한다. This paper wishes to analyze perception of forwarder about linkage-drive between Trans Korea Railway(TKR) and Trans Siberian Railway(TSR)-Trans China Railway(TCR) that is center of continent transport railroad. This study method and detailed contents are describing in paper Chapter 4 which see, and the study analysis used SPSS 10.0. The interest about railway through the Northeast Asia Area is appeared with Gyeong-wei Line restitution construction work at September through the South-North Summit-level Conference which hold in June, 2000. This Northeast Asia Area is bounded with a close relationship each other -Russia, China, Korea Peninsula, and Japan. And Korea Peninsula is located in center of these nations, so is doing the important duties in the Northeast Asia Area. Therefore This paper is analyzed the linkage-drive process of TKR after is examined the recent present statue and problem point about TSR-TCR. And I is discussed about perception improvement plan to the object of the forwarder which engaged now in Seoul. This analysis is examined with the question investigation. I could know that forwarders are not comprehend perfectly the concept about linkage-drive of continent cross-transport railway and TKR that doing now combined transportation.

침전성인자를 이용한 생물학적 고형물의 침전속도식과 고형물 플럭스 분석

김진우,최영균,이종훈,김희준,정태학 대한상하수도학회 2002 상하수도학회지 Vol.16 No.3

Equations on settling velocity of the activated sludge were developed by including sludge settleability parameters (SSP) and solids flux at a secondary settling tank was analyzed using the empirical equations, and an optimal solids loading rate was evaluated in this study. SVI, SSVI, DSVI and SSVI_3.5 were adopted as the SSP and a best fitting between observed and calculated zone settling velocity was obtained when SSVI_3.5 was used. Measured solids flux at the secondary settling tank was lower than that recommended by the national design criteria. Optimal solids loading rate and subsequent limiting solids flux can be derived if SSVI_3.5 is used instead of other SSP. Limiting solids flux calculated using SVI showed higher value than that calculated using SSVI_3.5 and the limiting solids flux could be better estimated when SSVI_3.5 was used because the calculated zone settling velocity using SSVI_3.5 was closer to the measured value.