직장인 음주 정의와 측정

김혜련,김한나 서울여자대학교 사회과학연구소 2012 사회과학논총 Vol.19 No.-

본 연구의 목적은 직장인 음주는 어떻게 정의하고, 어떻게 측정되어야 하는지를 살펴보는 것이다. 이를 위하여 우리나라에서 이루어진 직장인 대상 음주 연구와 외국에서 이루어진 직장인 음주 연구논문들을 검토하여 보았다. 그 결과, 많은 직장인 음주 연구들이 일상적인 음주(usual drinking) 즉, ‘직장 밖에서의 음주(off-the-job drinking)’ 혹은 ‘작업무관 음주(overall drinking)’만을 측정한 경향이 있음을 발견할 수 있었다. 연구자는 직장인 음주는 ‘직장 밖에서의 음주(off-the-job drinking)’ 뿐만 아니라 ‘직장 내에서의 음주(on-the-job drinking)’ 모두 포함해서 측정해야 한다는 Frone(2004)의 주장에 동의한다. 덧붙여 연구자는 우리나라 직장인 음주를 측정할 경우에는 Frone (2004)이 주장하는 ‘직장 밖에서의 음주(off-the-job drinking)’ 뿐만 아니라 ‘직장 내에서의 음주(on-the-job drinking)’ 이외에도 음주회식을 반드시 포함해야 한다는 우리나라 직장인 음주 연구자들의 의견을 적극 수용할 필요가 있음을 언급하였다. 특히 주목되는 것은 Mangione 등(1999)의 ‘작업 중 음주(drinking on the job)’척도로 ‘직장 내에서의 음주(on-the-job drinking)’와 ‘음주회식’을 측정하는 데에 적절한 척도라고 보았다. This project in its present form is written with the purpose of reexamining the definition and measurement of employee alcohol use:how to define and measure the employee alcohol use. Current standards prevalently used in domestic and foreign documents have the tendency to be based only on "usual drinking," also known as 'off-the-job drinking'. Contrary to these standards, we agree with Frone’s argument (2004) of measuring employee alcohol use:we must take into account both on- and 'off-the-job drinking 'comprehensively. Additionally, we assert, in concurrence with many Korean alcohol researchers, that after-working hours dinners among colleagues, which are usually accompanied by drinking, should also be included in making these measurements. For measuring 'on-the-job drinking' and after-working hours drinking, we found Mangione’s method (1999) to be most appropriate. Key Words:Employee Alcohol-Use, Definition, Measurement

THE EFFECTS OF POLYPHENOL CONTENT AND ANTIOXIDANT ACTIVITY OF BROWN ALGA Eisenia bicyclis EXTRACT FERMENTED BY PROBIOTICS

Hae-Na Han,Eun-Hye Lee,Sung-Hwan Eom,Young-Mog Kim 한국수산과학회 양식분과 2015 한국수산과학회 양식분과 학술대회 Vol.2015 No.5

일부 만 30세 이상 성인에서 구강건조증 관련요인 분석

한해성 ( Hae Seong Han ),권다애 ( Da Ae Kwon ),김리나 ( Ri Na Kim ),김유나 ( Yu Na Kim ),이결희 ( Gyeol Hui Lee ),이나람 ( Na Ram Lee ),이다정 ( Da Jeong Lee ),이승희 ( Seung Hui Lee ),최준선 ( Jun Seon Choi ) 한국치위생과학회 2013 치위생과학회지 Vol.13 No.1

The aim of this study was to analyze factors related to xerostomia in adults aged 30 years and over. The data were analyzed using the t-test, one-way ANOVA and multiple linear regression analysis in the SPSS version 12.0 program. The results were as follow. 1. The respondents who were older than 51 years old, unemployed and had less than 3 million won of average monthly income were more aware of xerostomia (p<0.05). 2. The respondents who answered poor and moderate for their general and oral health and the group with duplicate medication and comorbidity were more aware of xerostomia (p<0.05). 3. The respondents that had problems in chewing, communication, ordinary activities and complained of pain? discomfort and suffered from anxiety depression were more aware of xerostomia (p<0.001). 4. The respondents that answered frequent dryness on their skin, eyes, lips, and nasal mucosa were more aware of xerostomia (p<0.001). 5. Xerostomia showed highest correlation with quality of life (b=0.436) followed by the number of medications (b=0.239), sense of entire body dryness (b=0.200), feeling of hopelessness (b=0.160) and number of oral mucosa disease symptoms (b=0.099) (p<0.05). According to the results of the study, xerostomia may cause deterioration in quality of life. Thus, it is advised to improve the patient management system among dental professions to prevent various complications caused by xerostomia and conduct regular health education on the cause and management method of xerostomia.

대황( Eisenia bicyclis) 추출액의 항산화 및 항염증 활성에 대한 유산균 발효의 영향

한해나 ( Hae Na Han ),엄성환 ( Sung Hwan Eom ),김지훈 ( Ji Hoon Kim ),김덕훈 ( Deok Hoon Kim ),김송희 ( Song Hee Kim ),김윤혜 ( Yunhye Kim ),염승목 ( Seung Mok Yeom ),김영목 ( Young Mog Kim ) 한국수산과학회(구 한국수산학회) 2015 한국수산과학회지 Vol.48 No.2

This study was conducted to evaluate the effect of lactic acid bacterial fermentation on the antioxidant and antiinflammatory activity of an edible brown alga, Eisenia bicyclis. Lactic acid bacteria were inoculated into and cultivated in E. bicyclis water extract. The antioxidant activity of the extract was assayed before and following fermentation. Antioxidant activity was determined by assaying the levels of radical scavenging activity against 2,2′-diphenyl-1-picrylhydrazyl (DPPH), hydroxyl radical and alkyl radical. The lactic acid bacterial fermentation of E. bicyclis extract resulted in enhanced antioxidant activity. The greatest enhancement of antioxidant activity was seen in the DPPH radical scavenging assay, in which E. bicyclis extract was fermented by Pediococcus pentosaceus MBP-34 strain for 12 h. This fermented extract also exhibited higher inhibitory activity (96.66%) on nitric oxide production compared with other lactic acid bacterial fermented extracts or raw extract (189.60%). In conclusion, fermentation by bacterial strain is an attractive strategy for developing value-added food ingredients.

기혼남녀근로자의 일ㆍ가족 균형과 관련요인

한경혜(Han Gyoung-Hae)ㆍ장미나(Chang Mi-Na) 한국가족학회 2009 가족과 문화 Vol.21 No.1

본 연구는 기혼근로자들이 지각하는 일ㆍ가족 균형수준 및 관련요인에 있어서의 성별차이를 탐색하는 것을 목적으로 하여 수행되었다. 이를 위하여, 16개의 일터에서 정규직으로 종사하는 총 688명의 기혼남녀 근로자들을 대상으로 주관적으로 인식하는 일ㆍ가족 균형수준과, 가족 및 작업환경 특성별 균형인식의 남녀차이를 위계회귀분석을 통하여 탐색하였다. 주요 분석결과는 다음과 같다. (1) 여성이 남성에 비하여 두 역할간의 균형감을 높게 인식하고 있는 것으로 나타났다. (2) 가족과 작업환경 특성으로 구성된 본 연구모형 중 균형수준에 대한 대개의 설명력은 직업특성에 집중되어 있으며, 그 중 업무량이 가장 큰 영향을 미치는 것으로 나타났다. (3) 남녀에게 공통적으로 영향을 미치는 요인은, 근무시간과 업무량, 그리고 배우자로부터의 지원정도인 것으로 나타났다. (4) 남녀 간 차별적인 기제도 관찰되었는데, 직무융통성은 남성에게 그리고 직무통제감은 여성에게 유의한 정적영향을 미쳤다. 이러한 주요결과에 기초하여 기혼남녀근로자가 주관적으로 인식하는 일ㆍ가족 균형의 의미와 인식과정에서의 젠더차이를 논의하였다. This study examines the level of perceived work-family balance reported by married employees, and how environmental characteristics of work and family are related to their perceptions of balancing the two, both in regards of gender differences. Data were gathered from 688 employees (male: 485, female: 203) working in sixteen major firms in Korea. Hierarchical regressions were conducted on perceived work-family balance using categorical independent variables (environmental characteristics of family and work, respectively) including gender interaction terms, and OLS regression was conducted on two separate models for men and women. The results were: (1) women reported to have more balanced life than men. (2) Work environmental characteristics contributed the most in explaining the variance of the model. (3) There were similarities as well as differences in perceived work-family balance between men and women. Among family characteristics, higher level of spouse support was associated with feeling more balanced in both groups. (4) Among work characteristics, time pattern variables such as weekly working hours and overtime work were negatively associated with feeling balanced in both genders. However, job flexibility was positively associated with men's sense of balance, and job controls were positively associated with women's. Gender differences both in the meaning of perceived balance and process of perception were discussed based on these findings.

B형 간염 백신의 접종 횟수에 따른 항체 생성률에 대한 고찰

한혜경,엄미령,이성자,최경훈,이미나,유병훈 대한감염학회 1996 감염 Vol.28 No.1

목적 : B형 간염 혈장백신에 의한 항체 양성률은 90-95% 이상으로 보고되고있고 저자마다 결과의 차이가 있었다. 또한 동일개체 내에서 항체가 변화에 대한 연구가 많지 않아 저자들은 동일 개체에서의 시간경과에 따른 항체가 변화와 B형 간염백신접종 후 항체가 형성되지 않았던 아동들에게 백신 재접종 후 항체가와 항체양성률이 어떻게 변화하는지 알아보고자 본 연구를 시도하였다. 방법: 1994년 3월부터 1995년 6월까지 제일병원에서 B형 간염백신(HepavaxR)을 출생시, 1개월, 6개월에 접종받은 소아중 934명을 대상으로하여 생후 9개월에 항원(HBsAg), 항체가(Ant-HBs titer)를 측정하여 이중 항체가 형성되지 않은 소아에게 1회 추가접종후 4주후에 다시 항체가를 측정하였다. 이중 항체가 형성안된 소아에게 5차, 6차 접종후 3개월후에 다시 항체가를 측정하였다. 이들중 HBsAg양성 산모의 소아들에겐 생후 3개월 때 항원, 항체 검사를 실시 하였다. 검사방법은 RIA(radioimmunoassay:Abbott Laboratories)로 하였다. 결과: 1)2차 백신접종후(간염항원 양성 산모의 소아들중 생후 3개월인 소아) 검사한 HBsAb역가가 10mIU/ml 이상인 경우는 63명중 22명(34.9%)이었고 이중 항체가 형성안된 아동중 4차 접종후 검사가 시행된 172명중 101명(58.7%)이 10mIU/ml 이상이었다. 5차, 6차 백신접종후 검사가 시행된 13명중 4명이 10mIU/ml이상이었다. 2) 4차 백신 접종후 누적 항체양성률은 90.8%였고, 6차 백신 접종후는 98.7%였다. 결론: 3차 백신 접종후 항체 음성인 소아에게 4차 접종후 항체양성률이 증가되었다. B형 간염 백신 3차 접종후 선별 검사를 실시하여 항체 음성인 아동에게 추가접종이 필요할것으로 생각된다. Background : The seroconversion rate of hepatitis B after three consecutive vaccinations is estimated to be approximately 90%. We have given booster injections to the seronegative children with the fourth, fifth or sixth vaccination and estimated the seroconversion rate of hepatitis B (?? : Korean Green Cross Corporation) in relation to the number of vaccination. Methods : Serum samples were obtained from 934 babies who visited Cheil Hospital at 9 months of age (3 months after the 3rd vaccination) to determine the presence of HBsAg and titer of anti-HBs. The cases of negative anti-HBs were given a booster dose and anti-HBs titer was tested 4 weeks later. The babies who still had negative anti-HBs after the 4th dose were given the 5th and the 6th doses and anti-HBs titer was tested. RLA (Abbott Laboratories, U.S.A.) was used to determine the titers of anti-HBs. Seventy-eight babies born yo mothers who were HBsAg-positive were tested for HBsAg and titers of anti-HBs at 3 months of age after the 2nd vaccination. Results: 1) Twenty-two babies out of 64(34.9%) showed seroconversion after the 2nd vaccination. Six hundred babies out of 893(67.2%) showed seroconversion after the 3rd vaccination. Among the babies who were given the 4th dose 101 out of 172 (58.7%) babies showed seroconversion and for the 6th dose 4 out of 13 babies. 2) Cumulative seroconversion rate was 90.8% and 98.7% after the 4th and 6th vaccination, respectively. 3) The geometric mean titer (GMT) of anti-HBs was 19.2mIU/ml after the 2nd vaccination, 112.7mIU/ml after the 3rd vaccination and 57.1mIU/ml after the 4th vaccination. Conclusion : Seroconversion rate increased after the 4th dose for the babies who had negative anti-HBs even after the 3rd vaccination. Therefore, we recommend to screen for anti-HBs after the 3rd vaccination and to give booster injections for those who are negative anti-HBs.

Gingivitis Reduction Effect by Using Dentifrices Containing Resveratrol, Catechin and Baicalin

Han Na Kwak,조자원,Mi-Hae Yun 대한예방치과학회 2022 International Journal of Clinical Preventive Denti Vol.18 No.4

Objective: The purpose of this study was to investigate the effects of resveratrol, catechin, and bacalin on gingivitis and the membranes of dental bacteria. Methods: Thirty subjects were divided into experimental deterrent, comparative deterrent, negative control, and positive control groups each.The papilla marginal gingivitis index (PMA index), Talbott's gingival index, PHP index, and Turesky plaque index were used in the assessments and the following results were obtained. Results: PMA index measurement showed that the PMA index was significantly lower in the experimental and positive control group than in the negative control group after 4 weeks of experiment (p<0.01). The Talbott gingival was lowered to a significant level before the experiment in the experimental and positive control groups. In the control group, the gingivitis index was significantly higher than that of the control group after 4 weeks of experiment (p<0.01). For PHP index measurement, significant difference between the four groups before, one week, and two weeks after the experiment was observed. The PHP index was significantly lower in the experimental group than in the negative control group after 4 weeks of experiment (p<0.01). Bacterial count obtained using Turesky plaque index did not show any significant difference between the groups before, 1 week, and 2 weeks after the experiment. Turesky plaque index was significantly lower in the experimental group than in the negative control group after 4 weeks of experiment (p<0.01). Conclusion: In this study, we found that dentrifice containing resveratrol, catechin, and baicalin was effective against gingivitis and dental plaque.

Two cases of folliculosebaceous cystic hamartoma

( Han-na Kim ),( Anna Kim ),( Hae Jun Song ),( Jiehyun Jeon ),( Yoo Sang Baek ) 대한피부과학회 2022 대한피부과학회 학술발표대회집 Vol.73 No.2

Geranylgeranylacetone Ameliorates Intestinal Radiation Toxicity by Preventing Endothelial Cell Dysfunction

Han, Na-Kyung,Jeong, Ye Ji,Pyun, Bo-Jeong,Lee, Yoon-Jin,Kim, Sung-Ho,Lee, Hae-June MDPI 2017 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.18 No.10

<P>Radiation-induced intestinal toxicity is common among cancer patients after radiotherapy. Endothelial cell dysfunction is believed to be a critical contributor to radiation tissue injury in the intestine. Geranylgeranylacetone (GGA) has been used to treat peptic ulcers and gastritis. However, the protective capacity of GGA against radiation-induced intestinal injury has not been addressed. Therefore, we investigated whether GGA affects intestinal damage in mice and vascular endothelial cell damage in vitro. GGA treatment significantly ameliorated intestinal injury, as evident by intestinal crypt survival, villi length and the subsequently prolonged survival time of irradiated mice. In addition, intestinal microvessels were also significantly preserved in GGA-treated mice. To clarify the effect of GGA on endothelial cell survival, we examined endothelial function by evaluating cell proliferation, tube formation, wound healing, invasion and migration in the presence or absence of GGA after irradiation. Our findings showed that GGA plays a role in maintaining vascular cell function; however, it does not protect against radiation-induced vascular cell death. GGA promoted endothelial function during radiation injury by preventing the loss of VEGF/VEGFR1/eNOS signaling and by down-regulating TNFα expression in endothelial cells. This finding indicates the potential impact of GGA as a therapeutic agent in mitigating radiation-induced intestinal damage.</P>

측쇄형 광기능성 고분자에서의 편광홀로그램 특성

나혜섭,한양규,김필수,송석호,오차환,곽장만,주원제 漢陽大學校 自然科學硏究所 1999 自然科學論文集 Vol.18 No.-

측쇄형으로 서로 대칭인 두 광기능성 그룹들(4-cyanoazobenzene groups)을 표함하는 유기고분자(side-chain polymalonic esters with two symmetrical photoresponsive groups, PCN)에 이광파혼합을 이용하여 소거가 가능한 회절격자를 형성하였다. 이는 두 조사광들의 편광합이 λ/2sinθ의 주기로 공간적으로 변하고, 이에 의해 측쇄형 광기능성 분자군은 편광 방향에 수직한 면으로 정렬을 하여 매질의 흡수율 변조를 야기한다. 흡수율의 변조는 klamers-kronig 관계식에 의해 굴절율의 변조로 나타나며[1], 이로부터 편광 홀로그램이 기록된다. We investigate erasable polarization holographic gratings recorded with two-wave mixing in photoanisotropic organic materials which were side-chain polymalonic esters with two symmetrical photoresponsive groups(4-cyanoazobenzene groups). The superposition of polarizations of two writing beams varies spatially with a period of λ/2sinΘand accordingly side-chain photoresponse groups reorient perpendicular to the superposed polarization and thus the modulation of absorption of the polymers is induced. The phase polarization hologram is recorded with the modulation of refractive index which is related with absorption by klamer-kronig relation.