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Hae-Kyoung Han,Sung-Sook Choi,Ye-Rie Kim,Hyun-Jung Kim,Gil-Myung Kang,Mi-Sook Dong,Chun-Soo Na,Ha Sook Chung 한국식품영양과학회 2006 Preventive Nutrition and Food Science Vol.11 No.2
Alnus japonica Steud (Betulaceae) has long been used as a Korean traditional medicine for gastric disorders, hepatitis, and fatty liver. As a part of our study on the identification of secondary metabolites of naturally occurring bioactive compounds, we isolated 1,7-bis(4-hydroxyphenyl)-3,5-heptanediol (1), 5-hydroxy-1,7-bis(4-hydroxyphenyl)-3-heptanone (2), 5,3'-dihydroxy-7,4'-dimethoxyflavone (3) and 3,5,7,3',4'-pentahydroxyflavone (4) from the dichloromethane and ethylacetate-soluble fractions of Alnus japonica Steud. These compounds showed significant antioxidant activity in a concentration-dependent manner. The IC?? values of compounds 1, 2, 3 and 4 were 30.1, 37.4, 20.2 and 13.7 ㎍/mL, respectively, through the scavenging capacity of 1,1-diphenyl-2-picrylhydrazyl radical assay.
Chun, Kyoung-Yong,Jung, Seung Il,Choi, Hae Young,Kim, Jong-Uk,Lee, Cheol Jin American Scientific Publishers 2009 Journal of Nanoscience and Nanotechnology Vol.9 No.3
<P>Thin multi-walled carbon nanotubes (MWCNTs) were successfully synthesized by a rapid thermal chemical vapor deposition (RTCVD) method using a liquid catalyst. The growth of the thin MWCNTs was achieved by decomposition of C2H2 over Fe-Mo/MgO/citric acid directly at 700 degrees C for 30 min. Most thin MWCNTs, which had about 6 approximately 8 graphene layers, showed high purity (approximately 90%) and good crystallinity. Moreover, they showed homogenous morphology and uniform diameters. The average outer diameter of the thin MWCNTs was about 8 nm. The uniform diameter and good homogeneity of thin MWCNTs were mainly attributed to prevention of catalyst agglomeration at high temperature due to a short reaction time, and the high purity of thin MWCNTs was caused by suppression of the residual CNT growth after finishing a reaction in RTCVD process. Field emission properties of the thin MWCNTs were measured in a vacuum chamber at a pressure of less than 2 x 10(-7) Torr. The turn-on field was about 3.35 V/microm at the emission current density of 0.1 microA/cm2, and the emission current density was 2.5 mA/cm2 at an applied field of 6.7 V/microm. Particularly, the thin MWCNTs showed strong emission stability at emission current density of 0.8 mA/cm2 for 20 h.</P>
( Hae Hoon Park ),( Russell B Millar ),( Chang Doo Park ),( Seong Wook Park ),( Sung Il Lee ),( Bong Seong Bae ),( Heui Chun An ),( Sam Kwang Cho ),( Kyoung Hoon Lee ) 한국어업기술학회 2014 수산해양기술연구 Vol.50 No.1
To compare the catches made using gillnets, trammel nets, and gillnets with supporting lines, several experiments were conductedwith commercial vessels near Uljin and Pohang in Eastern Korea between July 2010 and May 2011. Two sets of 13 differentnets were used, including 5 panels of gillnets and trammel nets each with stretched mesh sizes of 7.6, 9.1, 10.6, 12.1, and 13.6cm and 3 panels of gillnets with a mesh size of 9.1 cm with supporting lines with different line spacing. The outer (stretched)mesh size of the trammel nets measured 51.5 cm. The target fishes of the fishing nets were various types of flounders. The catchrate of flounders was 50.7% of the total catch in weight. The total catch for all nets was 443.8 kg. The predominant species waspointhead flounder (Cleisthenes pinetorum). The total catch by trammel nets was 1.4 times that of the comparable gillnets. Butmore pointhead flounder were caught by gillnets than by trammel nets, though there was no significant difference. Fishermencatching the pointhead flounder in Korea said that there was no need to use trammel net to catch it; this was an unexpectedfinding compared to the findings of other flounder fisheries. The amounts of roughscale sole, brown sole, and blackfin floundercaught by trammel nets were greater than those caught by gillnets. The mean lengths (standard deviation) of blackfin flounder,pointhead flounder, brown sole, and roughscale sole were 21.0 (4.57), 22.9 (3.40), 24.7 (4.90), and 28.3 (5.43) cm, respectively;there were significant differences in mean length (p < 0.00001). Therefore, in order to catch flounder efficiently, the fishing netsand mesh size should be chosen according to the target species. One advantage of using supporting lines is that it prevents breakageby strengthening the material especially when utilized on a rough bottom. Catch by using gillnet with supporting lines wasnot greater than that by using trammel net for the conservation of fisheries resources.
Han, Hae-Kyoung,Choi, Sung-Sook,Kim, Ye-Rie,Kim, Hyun-Jung,Kang, Gil-Myung,Dong, Mi-Sook,Na, Chun-Soo,Chung, Ha-Sook The Korean Society of Food Science and Nutrition 2006 Preventive Nutrition and Food Science Vol.11 No.2
Alnus japonica Steud (Betulaceae) has long been used as a Korean traditional medicine for gastric disorders, hepatitis, and fatty liver. As a part of our study on the identification of secondary metabolites of naturally occurring bioactive compounds, we isolated 1,7-bis(4-hydroxyphenyl)-3,5-heptanediol(1), 5-hydroxy-1,7bis(4-hydroxyphenyl)-3-heptanone(2), 5,3'-dihydroxy-7,4'-dimethoxyflavone(3) and 3,5,7,3',4'-pentahydroxyflavone(4) from the dichloromethane and ethylacetate-soluble fractions of Alnus japonica Steud. These compounds showed significant antioxidant activity in a concentration-dependent manner. The $IC_{50}$ values of compounds 1, 2, 3 and 4 were 30.1, 37.4, 20.2 and 13.7 ${\mu}g/mL$, respectively, through the scavenging capacity of 1,1-diphenyl-2-picrylhydrazyl radical assay.
Woo Kyoung Kim,Ji Hae Kim,Da Hee Jeong,Young Hee Chun,Sun Hee Kim,Kang Jin Cho,Moon-Jeong Chang 한국영양학회 2011 Nutrition Research and Practice Vol.5 No.4
In this study, we investigated the effects of the ethanol extract of aerial parts of Raphanus sativus L. (ERL) on breast cancer cell proliferation and gene expression associated with cell proliferation and apoptosis in MDA-MB-231 human breast cancer cells. The MDA-MB-231 cells were cultured in the presence or absence of various concentrations (100, 200, or 300 μg/mL) of ERL. ERL significantly decreased cell proliferation after 48 h of incubation (P < 0.05). The protein and mRNA expression of ErbB2 were decreased significantly in a dose-dependent manner (P < 0.05). The protein expression of ErbB3 was decreased significantly at an ERL concentration of 300 μg/mL (P < 0.05), and mRNA expression of ErbB3 was decreased significantly in a dose-dependent manner (P < 0.05). The protein expression of Akt was decreased significantly at the ERL concentration of 200 μg/mL (P < 0.05), and the protein expression of pAkt was decreased significantly in a dose-dependent manner (P < 0.05). The mRNA expression of Akt was decreased significantly at the ERL concentration of 200 μg/mL ERL (P < 0.05). The protein and mRNA expression of Bax were increased significantly at ERL concentrations of 200 μg/mL or higher (P < 0.05). The protein expression of Bcl2 was increased significantly at ERL concentrations of 100 μg/mL or higher (P < 0.05), and mRNA expression of Bcl2 was increased significantly at an ERL concentration of 300 μg/mL (P < 0.05). In conclusion, we suggest that Raphanus sativus, L. inhibits cell proliferation via the ErbB-Akt pathway in MDA-MB-231 cells.