http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
The Korean Hypertension Cohort study: design and baseline characteristics
( Hae-Young Lee ),( Ju-Yeon Lee ),( Ho-Gyun Shin ),( Song-Hee Cho ),( Kyun-Ik Park ),( Gyu-Chul Oh ),( Seung-Pyo Lee ),( Hogon Kim ),( Hee-Sun Lee ),( Kwang-Il Kim ),( Si-Hyuck Kang ),( Jang Hoon Lee 대한내과학회 2021 The Korean Journal of Internal Medicine Vol.36 No.5
Background/Aims: Hypertension (HT) has a significant impact on public health and medical expenses. However, HT is a chronic disease that requires the long-term follow-up of a large number of patients. Methods: The Korean Hypertension Cohort (KHC) study aimed to develop a model for calculating cardiovascular risk in HT patients by linking and utilizing the detailed clinical and longitudinal data from hospitals and the national health insurance claim database, respectively. This cohort had a planned sample size of over 11,000 HT patients and 100,000 non-HT controls. Eligible patients were hypertensive patients, who were presenting for the first time and were diagnosed with HT as a main disease from 2006 to 2011. Long-term survival data over a period of approximately 9 years were obtained from the national health insurance claim and national health examination data. Results: This cohort enrolled 11,083 patients with HT. The mean age was 58.87 ± 11.5 years, 50.5% were male, and 31.4% were never-treated HT. Of the enrolled patients, 32.9% and 37.7% belonged to the high and moderate cardio-vascular risk groups, respectively. Initial blood pressures were 149.4 ± 18.5/88.5 ± 12.5 mmHg. During the 2 years hospital data follow-up period, blood pressures lowered to 130.8 ± 14.1/78.0 ± 9.7 mmHg with 1.9 ± 1.0 tablet doses of antihypertensive medication. Cardiovascular events occurred in 7.5% of the overall patients; 8.5%, 8.8%, and 4.7% in the high, moderate, and low risk patients, respectively. Conclusions: The KHC study has provided important information on the long-term outcomes of HT patients according to the blood pressure, comorbid diseases, medication, and adherence, as well as health behaviors and health resource use.
Overexpression of KAI1 Protein in Diabetic Skin Tissues
Cho, Moon Kyun,Kwon, Sun Bum,Kim, Chul Han,Lee, Yoon-Jin,Nam, Hae-Seon,Lee, Sang-Han Korean Society of Plastic and Reconstructive Surge 2014 Archives of Plastic Surgery Vol.41 No.3
Background Patients with diabetes mellitus often have a difficult life, suffering from foot ulceration or amputation. Diabetes is characterized by chronic inflammation, and one of the features of inflammation is hypoxia. Recently, it has been reported that KAI1 is a hypoxia target gene. There is no published research on hypoxia-related KAI1 protein levels in human diabetic skin. Therefore, we have investigated the expression of KAI1 protein in diabetic skin tissue in vivo. Methods The expression of KAI1 protein was evaluated by western blotting in 6 diabetic skin tissue samples and 6 normal skin samples. Immunohistochemical staining was carried out to identify KAI1 expression. Results The western blotting revealed significantly increased expression of the KAI1 protein in diabetic skin tissues as compared to normal skin tissues. Immunohistochemical examination demonstrated that KAI1 was expressed in all diabetic skin tissues with moderate-to-strong positivity and weakly expressed in normal skin tissues. Conclusions Our data suggest that a high expression of the KAI1 protein can be observed in diabetic skin tissue. To the best of our knowledge, this is the first report suggesting that KAI1 protein expression in diabetic skin tissues may be associated with chronic inflammatory states and hypoxia.
Axial Neck Pain after Cervical Laminoplasty
Cho, Chul-Bum,Chough, Chung-Kee,Oh, Jong-Yang,Park, Hae-Kwan,Lee, Kyung-Jin,Rha, Hyoung-Kyun The Korean Neurosurgical Society 2010 Journal of Korean neurosurgical society Vol.47 No.2
Objective : It has been demonstrated that cervical laminoplasty is an effective and safe method of treating multi-level cervical spondylotic myelopathy and ossification of the posterior longitudinal ligament. However, recent reports have suggested that axial neck pain is frequently encountered after cervical laminoplasty. The aim of the present study was to determine clinical significance of the C7 spinous process on axial neck pain after cervical laminoplasty. Methods : A total of 31 consecutive patients that underwent cervical laminoplasty between March 2002 and December 2008 were reviewed. The authors evaluated and compared axial neck pain and lordotic angle in patients that underwent C7 spinous process preserving surgery (group 1, n=16) and in patients in which the C7 spinous process was sacrificed (group 2, n=15). Results : Severe or moderate early axial pain occurred in 56.2% of patients in group 1 and in 86.6% in group 2. Severe or moderate late axial pain occurred in 12.5% in group 1 and in 73.3% in group 2. Eighty-Six percent of patients in group 2 and 43% in group 1 experienced aggravation of their axial neck pain during the early postoperative period. Aggravation of axial neck pain during early postoperative period was less common in group 1 but not statistically significant (p=0.073). Sixty-six percent of patients in group 2 and 12% in group 1 had aggravated axial neck pain at late postoperative period and aggravation of late axial neck pain was significantly less common in group 1 (p=0.002). Conclusion : The present study demonstrates that C7 spinous process preserving laminoplasty decreases the incidence of aggravated axial neck pain after cervical laminoplasty.
Thalamic Deep Brain Stimulation for Writer's Cramp
Cho, Chul-Bum,Park, Hae-Kwan,Lee, Kyung-Jin,Rha, Hyoung-Kyun The Korean Neurosurgical Society 2009 Journal of Korean neurosurgical society Vol.46 No.1
Writer's cramp is a type of idiopathic focal hand dystonia characterized by muscle cramps that accompany execution of the writing task specifically. There has been renewed interest in neurosurgical procedures for the treatment of dystonia over the past several years. In particular, deep brain stimulation (DBS) has received increasing attention as a therapeutic option for patients with dystonia. However, to date, limited reporters made investigations into DBS in relation to the Writer's cramp. In this case, unilateral Ventro-oralis complex (Vo) DBS resulted in a major improvement in patient's focal dystonic movement disorders. Her post-operative Burke-Fahn-Marsden Dystonia Rating (BFMDR) scale demonstrated 1 compared with pre-operative BFMDR scale 4. We conclude that thalamic Vo complex DBS maybe an important neurosurgical therapeutic option for Writer's cramp.
Stereotactic Radiosurgery with the CyberKnife for Pituitary Adenomas
Cho, Chul-Bum,Park, Hae-Kwan,Joo, Won-Il,Chough, Chung-Kee,Lee, Kyung-Jin,Rha, Hyoung-Kyun The Korean Neurosurgical Society 2009 Journal of Korean neurosurgical society Vol.45 No.3
Objective : In recent years, CyberKnife has emerged as an important treatment modality in the management of pituitary adenomas. Treatment results after performing CyberKnife and the complications of this procedure are reviewed. Methods : Twenty-six patients with pituitary adenomas received stereotactic radiosurgery with the CyberKnife (CKRS). The follow-up periods ranged from 7 months to 47 months (mean$\pm$SD : $30{\pm}12.7$ months). The patients consisted of 17 with non-functioning adenomas, 3 with prolactinomas and 6 with acromegaly. The change in the tumor volume, visual acuity, hormonal function, and complications by this therapy were analyzed in each case. Results : The tumor control rate was 92.3%. Hormonal function was improved in all of the 9 (100%) functioning adenomas. Hormonal normalization was observed in 4 of the 9 (44%) patients with a mean duration of 16 months. In two patients (7.6%), visual acuity worsened due to cystic enlargement of the tumor after CKRS. No other complications were observed. Conclusion : CyberKnife is considered safe and effective in selected patients with pituitary adenomas. However, longer follow-up is required for a more complete assessment of late toxicity and treatment efficacy.
Integration of a Passive-Type UHF RFID Tag Using Ferroelectric Memory Technology
Hae-Chan Park,Suk-Kyoung Hong,Ae-Kyoung Lee,Baek-Hee Lee,Hee-Bok Kang,Heon-Yong Chang,Ji-Hye Choi,Nam-Kyun Park,Sanghyun Park,Sung Joo Hong,Sung-Sil Cho,Sung-Yeon Hwang,Yoon-Jung Kim,Young-Jin Son 한국물리학회 2007 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.51 No.2I
We investigated a passive-type rewritable radio-frequency identification (RFID) tag operating at the UHF (860 . 960 MHz) band and using ferroelectric memory (FeRAM) technology. The transponder integrated circuit(IC) for the UHF RFID tag was implemented with 0.25-μm one-poly four-metal standard logic CMOS technology with the addition of a FeRAM and Schottky diodes. The Pb(Zr,Ti)O3(PZT) capacitor array with a unit area of 1.4 × 1.4 μm2 for the FeRAM-embedded RFID tag showed a remnant polarization of 30 μC/cm2 and a leakage current of 1 × 10.5 A/cm2 at 3 V after full process integration. The novel ferroelectric technology utilizing a stacked capacitor structure and a high capacitance PZT capacitor allowed a highly competitive transponder chip size (550 × 550 μm2) by reducing the area of the analogue circuit without adding any complexity to the process integration. The PZT capacitor-based analogue circuitry showed almost the same performance as that of conventional capacitor type circuitry. Thus, the ferroelectric memory technology is very promising for the realization of a cost-effective, passive-type, rewritable UHF RFID tag.
Hae Lim Baek,Yong Kyun Cho,Mi-Seung Shin,Song Mi Moon,Suyoung Kim,Kang-lock Lee,Young Rock Jang,Woo Suk Choi 중앙대학교 의과대학 의과학연구소 2013 中央醫大誌 Vol.38 No.4
Infective endocarditis caused by Aggregatibacter aphrophilus, which is one of the members of HACEK group, is rare and mitral valve is known as a prominently affected site in most cases. We report a case of isolated pulmonary valve infective endocarditis caused by A. aphrophilus in a patient with congenital heart disease. Twenty five-year-old woman with ventricular septal defect visited our hospital complaining fever lasting 3 weeks. Not any vegetation was observed at transthoracic echocardiography due to limited echo window. However, transesophageal echocardiography showed a small vegetation attached to the pulmonary valve. The patient was successfully treated with ceftriaxone for 4 weeks.
유리섬유 강화 폴리올레핀케톤 복합재료의 제조 및 특성에 대한 연구
조해석 ( Hae Souk Cho ),정재승 ( Jae Seung Chung ),백승조 ( Seung Jo Beak ),최원재 ( Won Jae Choi ),김진주 ( Jin Joo Kim ),윤성균 ( Sung Kyun Yoo ),이종찬 ( Jong Chan Lee ) 한국공업화학회 2012 공업화학 Vol.23 No.3
우수한 기계적 강도를 가지고 있는 폴리올레핀케톤 고분자를 합성하고, 우레탄과 아미노실란으로 표면 처리 된 유리 섬유를 도입하여 엔지니어링 플라스틱용 복합재료를 제조하였다. 유리섬유와 폴리올레핀케톤의 상용성을 확인하기 위해 주사 전자 현미경으로 복합재료의 파단면 형상을 확인하였고, 함유된 유리섬유의 크기와 양, 그리고 바인더의 종류에 따른 복합재료의 기계적 물성을 관찰하였다. 적절한 표면처리를 한 유리섬유로 강화된 폴리올레핀케톤 복합재 료는 좋은 계면 상용성을 보이며 향상된 기계적 강도를 가지고 엔지니어링 플라스틱 분야에서의 응용 가능성을 확인 할 수 있었다. Poly (olefin ketone) terpolymer having excellent mechanical properties was synthesized and composite materials of poly (olefin ketone) containing polyurethane/amino silane functionalized glass fibers were prepared. The compatibilities between the functionalized glass fiber and the polymer were characterized by observing the fracture surfaces of the composites using scanning electron microscopy (SEM). Mechanical properties of composites with different contents, diameters, lengths, and binders of glass fibers were also studied using universal testing machine (UTM). The introduction of suitably functionalized glass fiber into the poly (olefin ketone) produces composite materials having excellent mechanical properties and they are very promising alternative materials for the engineering plastic applications.