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RISS 인기검색어
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- 저자 : Hadipour, Maryam (검색결과 5 건)
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Preparation and characterization of plasma-sprayed nanostructured- merwinite coating on Ti-6Al-4V
Mohammadreza Hadipour,Masoud Hafezi,Saeed Hesaraki 한양대학교 세라믹연구소 2015 Journal of Ceramic Processing Research Vol.16 No.3
In the present study, synthesized nanostructured merwinite (Ca3MgSi2O8) bioactive coatings were successfully prepared by plasma-spray coating method. The phase composition and microstructure of the powders were examined by X-ray diffraction, scanning electron microscopy and transmission electron microscopy. Also the properties of the prepared coating were evaluated using XRD, AFM, SEM coupled with Energy-Dispersive X-ray analaysis and micro hardness analysis. XRD analysis indicated pure merwinite coatings were obtained. A uniform structure of the merwinite coating was found across the Ti-6Al4V surface, with a thickness and surface roughness of the coating of about 16 and 0.252 + −0.02 µm, respectively. The results indicated that merwinite coating was obtained with a uniform and dense microstructure at the interface of the Ti-6A l-4V surface. Taken together, the results obtained indicated that plasma sprayed merwinite coating may be a candidate for orthopedic implants.
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Protective Effects of Berberis vulgaris on Diazinon-Induced Brain Damage in Young Male Mice
Azadeh Sonei,Simin Fazelipour,Leila Kanaani,Mahsa Hadipour Jahromy 한국식품영양과학회 2020 Preventive Nutrition and Food Science Vol.25 No.1
Diazinon is an imminent and hazardous chemical organophosphate multiplex that is generally used as a pesticide but is toxic for many species particularly vertebrates. Berberry (Berberis vulgaris L., family Berberidaceae) is a plant that flourishes in Europe and Asia that has been largely investigated for its therapeutic effects. In the present study, we evaluated the protective effects of B. vulgaris on diazinon-induced brain damage in young male mice. Twenty-one young male albino mice weighing 18±2 g were divided in three equal groups of seven mice, and treated orally with either olive oil (control), diazinon 50 mg/kg+B. vulgaris extract 200 mg/kg, or diazinon 50 mg/kg. After three weeks, cerebrum and cerebellum samples were collected for antioxidant assays. The results indicated that diazinon increased oxidative stress in the brain of mice. The glutathione content and proceedings of antioxidant enzymes, such as glutathione peroxidase, superoxide dismutase, and catalase, were significantly reduced in both the cerebellum and cerebrum of diazinon-treated mice, compared with the control group. In addition, acetylcholinesterase (AChE) activity was inhibited by exposure to this pesticide. Administration of 200 mg/kg B. vulgaris extract with diazinon significantly decreased oxidative stress indices in all experiments. The results indicated that B. vulgaris extract has protective effects against lipid peroxidation of the cerebellum and cerebrum, and in regenerating AChE activity in the brain induced by diazinon.
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Vardanjani, Hossein Molavi,Heidari, Mohammad,Hadipour, Maryam Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.7
Background: Around half of input data in the global burden of disease cancer collaboration (GBD-CC) and GLOBOCAN projects come from low quality sources, mainly from developing countries. This may lead to loss of precision in estimates. Our question was: Are the absolute values and trends of the GBD-CC and GLOBOCAN estimates for lung cancer (LC) in Iran consistent with available statistics?. Materials and Methods: Incidence and mortality statistics were extracted from national reports (N.IRs & N.MRs) and GBD-CC (GBD-incidence & mortality) and GLOBOCAN databases for 1990-2013 where available. Trends were analyzed and absolute values and annual percentage changes (APCs) were estimated and compared. Incompleteness of case ascertainment at the Iranian national cancer registry and Iranian national civil registration was assessed for better understanding. Results: Trends of N.IRs were significantly rising for males (APC: 19.4; 95% CI: 12.5-26.7) and females (23.2; 16.0-30.8). Trends of GBD-incidence were stable for males (-0.2; -1.5-1.1) and females (-1.0; -2.3-0.4). Absolute N.IRs were less than GBD-incidence steadily except for 2009. Trend of N.MRs was increasing up to 2004, but stable thereafter. Trends of GBD-mortality were also stable. Absolute N.MRs were less than GBD-mortality for years up to 2003 and more than GBD-mortality since 2005. The estimates of GLOBOCAN were more than N.IRs and N.MRs. Conclusions: The GBD-CC and GLOBOCAN values for LC in Iran are underestimates. Generation of data quality indices to present along with country specific estimates is highly recommended.
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Mohammad Bayat,Atarodsadat Mostafavinia,Mohammad Bidram,Amirhossein Gomi Avili,Mohammadamin Mahmanzar,Seyed Ali Karimifard,Ensieh Sajadi,Abdollah Amini,Mahsa Hadipour jahromy,Seyed Kamran Ghoreishi,Su 한국실험동물학회 2019 Laboratory Animal Research Vol.35 No.4
In this probe, at first we examined the best route and dosage of arginine administration on wound healing in an excisional wound model in rats. Next, we intend to assess the impact of photobiomodulation (PBM) and arginine, individually and together, on the wound healing. In the pilot study, an excisional wound was made in each of 24 rats. There were 4 groups. Group 1 was the control group. In groups 2 and 3, wounds were topically treated with arginine ointments (ARG.) 2% and 5%, respectively. In group 4, arginine was injected (ARG. INJ.,i.p.). In the main phase, in 24 new rats, an excisional wound was made. There were 4 groups: group 5 served as the control. Wounds in group 6 were topically treated with ARG 2%. Wounds in group 7 were subjected to PBM. Wounds in group 8 were treated with PBM+ARG. 2%. On day 15, wound area measurement, wound strength, and stereological examination were performed. In the pilot study, we found that the ARG 2% ointment significantly decreased wound area than ARG. 5%, ARG. INJ. and control groups, and significantly increased wound strength compared to the control and ARG.5% groups. In the main phase, a significant decrease of wound area in all treatment regimens was induced. PBM + ARG. 2% and PBM treatment regimens significantly improved wound strength and almost all stereological parameters, compared to the control and ARG. 2% groups. PBM + ARG. 2% induced anti-inflammatory and angiogenic activities, and hastened the wound healing process in an excisional wound model in rats.
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