史料紹介 : 『御尋朝鮮覺書』(小田四郞兵衛著) 異本 『朝鮮風俗記』

하우봉,홍성덕,장순순,小幡倫裕 전북대사학회 1997 전북사학 Vol.19ㆍ20 No.-

영동지역 주요 3개 하천의 수질실태 및 관리에 관한 연구

박광하,민선홍,최봉종,전방욱 강릉대학교동해안지역연구소 1994 東海岸硏究 Vol.5 No.1

영동지방의 주요 3개 하천의 수질을 조사하고 QUAL-2E 모델을 적용하여 보았다. 강릉남대천은 각 수질항목에서 시기별, 정점별로 큰 차이를 보였으며, 일반적으로 상류의 수질은 하류로 갈수록 생활오수의 유입으로 수질이 악화되는 전형적인 양상을 나타내었다. 양양남대천은 강릉남대천 및 삼척오십천에 비하여 시기별 변이폭이 좁았으며 각 정점별의 수질도 양호한 것으로 나타났다. 삼척오십천은 시기별보다는 정점별 수질차이가 크게 나타났으며 오염된 상류의 수질이 자정작용에 의하여 개선되다가 다시 생활오수의 유입으로 인하여 악화되는 특이한 양상을 보였다. 모델링 결과 하천의 유속, 유량등의 실측 자료가 부족함에도 불구하고 강릉남대천과 양양남대천은 실측치와 예상치가 높은 상관관계를 나타내었다. 또한 이 모델을 사용하여 강릉남대천의 수질예측을 시도하였다. The water quality was monitored and QUAL-2E modelling was applied in three main stream of Youngdong area. Kangnung Namdaecheon was shown to be a typical stream that the downstream water quality was worse than in the upperstream. Water quality of Yangyang Namdaecheon was better than that of Kangnung Namdaecheon and Samchuk Osipcheon. The spatial variation of water quality was greater than the temporal variation in Samchuk Osipcheon: the polluted upperstream water got better in the midstream, but got worse gain in the downstream. Despite of the lack of suitable measurement data, Kangnung Namdaecheon and Ynagyang Namdaecheon showed good relationship between measured and obtained data: however Samchuk Osipcheon, which had many point sources and much pollution load, showed poor relationship. Based on this model, future water quality of Kangnung Namdaecheon was prospected.

안인 군선강의 이화학적 수질

민선홍,최봉종,김한수,김영하,박광하 강릉대학교동해안지역연구소 1993 東海岸硏究 Vol.4 No.3

1993년 2월부터 9월까지 4회에 걸쳐 명주군 군선강의 8개 지점을 대상으로 하여 수질 조사를 하였다. 수질 평가를 위하여서는 수온, pH, 용존 산소량, 화학적 산소 요구량, 생물학적 산소 요구량, 부유 물질, 암모니아성 질소, 아질산성 질소, 질산성 질소, 인산염 인, 계면 활성제, 대장균등을 측정 하였다. 본 하천의 상류쪽은 산성을 나타냈으며 하류쪽으로 갈수록 알카리성으로 나타났다. 또한 대장균수는 상대적으로 작았다. 그 원인은 광산 폐수때문인 것으로 나타났으며 하류쪽으로 갈수록 해수와 혼합되기 때문인 것으로 나타났다. The water quality was monitored from February through September, 1993 for four times on the eight sites of Gunseon Stream, Myungju. To monitor the water quality, water temperature, pH, Dissolved oxygen, Chemical oxygen demand, Biochemical oxygen demand, Suspended solid, Ammonia-nitrogen. Nitrite-nitrogen, Nitrate-nitrogen, Inorganic phosphate, Sulfactant, and E. coli MPN were chosen as parameters. The upstream was more acidic; downstream was more alkalic. The E. coli MPN value was relatively low due to the mine pollutant and seawater mixture.

질염의 치료 및 예방에 대한 Vagilac의 임상적 연구

김선행,홍성봉 최신의학사 1985 最新醫學 Vol.28 No.3

韓國 妊婦의 TORC H病原體에 關한 抗體 保有에 關한 硏究

柳承一,金善行,洪性鳳 고려대학교 의과대학 1985 고려대 의대 잡지 Vol.22 No.3

During the recent 15 years, there was a significant changes in the incidence of viral infection in pregnancy. In addition, TORCH agents are the most prevalent microbes among them, and their infections during pregnancy, either primary or recurrent, may affect the feauses in utero and the neonates at the time of delivery. Although we have achieved some progress in controlling them in the view point of prevention and treatment, but it is still insufficient. The purpose of this study is to determine the baseline prevalence of antibodies for TORCH agents during various stage of pregnancy in Seoul, Korea. From 92 asymptomatic pregnant women, 92 single serum sample were taken and examined the antibodies for TORCH agents by ELISA (C.M.V., R.V., H.S.V.) and H.A.I. test (Toxoplasmosis). The followings are the results. 1. The prevalences of antibodies to each of the TORCH agent were 1.08% for toxoplasma, 93.47% for C.M.V., 71.73% for R.V. and 84.74% for H.S.V. 2. The prevalences of antibodies for C.M.V. and R.V. were much higher in the term pregnancy group compared to early pregnancy. This findings suggest some evidence of vulnerability to viral infection during pregnacy. 3. The prevalences of C.M.V., R.V. and H.S.V. antibodies were in parallelism with the increasing age of women. Almost all women over 30-35 years had C.M,V., R.V., H.S.V. antibodies. 4. In multiparous women, the prevalences of antibodies for TORCH agents were higher than that in nulliparous women. 5. In the women with history of previous fetal wastage, the prevalence of TORCH antibodies were higher especially for C.M.V. compared with women without past history of previous fetal wastage.

妊娠中督症을 同伴한 妊婦의 胎盤內 免疫globulins, 補體(C₃) 및 纖維素源 沈着에 關한 免疫組織化學的 硏究

黃仁奎,金善行,洪性鳳 고려대학교 의과대학 1985 고려대 의대 잡지 Vol.22 No.1

Nowadays, it is generally accepted that immunological mechanisms are relevant in the materno-fetal relationship. And the abnormal deviation of maternal immune response to paternally derived or organ specific antigens is proposed as the pathogenesis of toxemia. The primary site of antigen-antibody reaction will be the choriodecidual junction because it is the area of direct contact and exchange between mother and feto-placental unit. Therefore this investigation has focused on the term placenta of toxemic women and demonstrated more heavier deposits of IgG, IgM, and fibrinogen in the villi of toxemic placenta than that of normal placenta by the treatment of deparaffinized specimen with anti-immunoglobulins antiserum and avidin-biotinylated peroxidase. The most striking reactions were produced by anti-IgG, anti-IgM, and anti-fibrinogen antiserum in this series. The followings are more detailed results. 1. Anti-IgG antiserum routinely reacted within the syncytiotrophoblast, the peripheral surface of the chorionic villi, as segmental or linear fashion. The staining was not seen in all villi and the pattern was granular or smooth with some areas of villi being more intensively stained than others. The degree and extent of staining were more dense and wide-spread in the placenta of toxemia than that of normal. 2.Anti-IgA antiserum reacted weakly and focally along with the surface of villi as segmental fashion. No difference of staining was noted between toxemic and normal placenta. 3. One of the most striking reaction was produced by anti-IgM antiserum. The pattern and distribution of staining were similar to anti-IgG antiserum treated specimen. There was noticeable difference in the degree and extent of staining between the placenta of toxemia and normal. 4. Generally, anti-complement (C₃) antiserum reacted weakly and focally. This finding stressed the immunological concept of toxemia. 5. One of the prominent reaction was also produced by anti-fibrinogen antiserum. The densely and homogeneously stained areas along the peripheral surface of the chorionic villi were impressive. The widely spreaded staining areas were also noted in the inter-villous spaces and fibrinoid(degeneration) areas which was connected to trophoblastic basement membrane as interrupted fashion. The degree and extent of staining produced by anti-fibrinogen antiserum had the most striking difference between the placenta of toxemia and normal. Above results may allow the conclusion that the more intense immunohistologic or histochemical changes in the placenta of toxemic pregnancy imply that toxemia has definite immunologic background different from that of normal pregnancy.

자율신경계의 활성도 측정을 위한 Data Acquisition System의 개발 및 임상응용

신동구,박종선,김영조,심봉섭,이상학,이준하 영남대학교 기초/임상의학연구소 2001 Yeungnam University Journal of Medicine Vol.18 No.1

Background: Power spectrum analysis method is a powerful noninvasive tool for quantifying autonomic nervous system activity. In this paper, we developed a data acquistion system for estimating the activity of the autonomic nervous system by the analysis of heart rate and respiratory rate variability using power spectrum analysis. Materials and methods: For the detection of QRS peak and measurement of respiratory rate from patient's ECG, we used low-pass filter and impedance method respectively. This system adopt an isolated power for patient's safety. In this system, two output signals can be obtained: R-R interval(heart rate) and respiration rate time series. Experimental ranges are 30∼240 BPM for ECG and 15∼80 BPM for respiration. Regults: The system can acquire two signals accurately both in the experimental test using simulator and in real clinical setting. Conclusion: The system developed in this paper is efficient for the acquisition of heart rate and respiration signals. This system will play a role in research area for improving our understanding of the pathophysiologic involvement of the autonomic nervous system in various disease states.

한국인 제2형 당뇨병 환자에 있어 지속적 피하 인슐린 주입법 치료시 Lispro insulin와 Regular insulin의 효과 비교

유재등,박봉안,류하근,류주성,김정수,김치훈,박선민,최수봉 건국대학교 의과학연구소 2001 건국의과학학술지 Vol.11 No.-

Objective: The Lispro insulin has faster onset of effects and shorter duration than the human regular insulin, an analog of human insulin. The differences in the pharmacodynamics between the two types of insulin in the continuous subcutaneous insulin infusion(CSII) with insulin pump for treating the Korean Type 2 DM patients were analyzed. The effects on the regulation of blood sugar, the amount of insulin injected, and the frequency of hypoglycemia were compared between the lispro insulin and the regular human insulin. Method and Material: One hundred and three Korean Type 2 DM patients were randomly divided into two groups, 49 Lispro insulin and 54 Regular insulin.(Table 1) Both groups were treated for 14 days. Also at a set time before meal, insulin was injected as bolus, using a portable insulin pump, in both groups, 15 minutes before for lispro insulin and 30 minutes before for human insulin The HbA1C, C-peptide, AC/PC, height and weight were measured for each patients at the time of admission. The peripheral blood sugar level and insulin injection profile were recorded 7 times per day for each patients. Results: After treating for 7 days and 14 days, the blood sugar level normalized in both groups. There weren't any significant differences in blood sugar levels in both groups at point of the study, and also there weren't any differences in the frequency of hypoglycemia. In order to maintain the normalized blood sugar level, the lispro insulin group had higher total daily insulin requirement than the regular insulin group after 14 days of treatment (0.90±0.35 vs 0.73±0.39u/kg/day, p<0.05) This difference is probably due to the difference in basement insulin requirements rather than prandial insulin requirements (0.32±0.1 vs 0.43± 0.09u/kg/day, p<0.001). Discussion: In the hospitalized Korean Type 2 DM patients with CSII treatment, continuous subcutaneous insulin infusion therapy using lispro insulin has convenience in usage compared to the regular insulin. However, there were not any differences in the blood sugar levels. Also lispro insulin requires more insulin in order to maintain normal blood sugar level, which is probably due to the increase in the basal requirement. Also there were not any difference in the frequency of hypoglycemia.

妊娠中毒症을 同伴한 妊産婦 및 新生兒 血淸 Immunoglobulins에 關한 硏究

薛弘烈,金善行,洪性鳳 고려대학교 의과대학 1985 고려대 의대 잡지 Vol.22 No.1

It has long been considered that toxemia of pregnancy might be an immunologic process and this study was designed to explore possible abnormalities in the immunologic process in toxemic pregnant women. IgG. IgA and IgM were measured by radial immunodiffusion plate technique in maternal and umbilical cord sera of toxemic patients and in normal pregnant cases at the time of delivery. The values obtained in the toxemic patients were compared with those from the normal term pregnant women, and the following results were obtained. 1. The level of IgG in maternal sera of toxemic group mere significantly decreased than that of the normal pregnant group. (p<0.05) 2. The levels of IgA and IgM in maternal sera demonstrated no significant difference between normal pregnant and toxemic patients. 3. Though the levels of IgG and IgA in cord sera of toxemic patient were slightly lower than those of the normal pregnant group, the difference was not statistically significant. 4. The level of IgM in cord sera of toxemic group was markedly lower than that of normal pregnant group and the difference was statistically significant. (p<0.05)

폐결핵으로 오인된 SIADH를 동반한 편평상피 세포폐암 1예

김순제,류하근,김선두,이길도,박봉안,류주성,유재등,김인숙,신현준,문언수 대한노인병학회 1999 Annals of geriatric medicine and research Vol.3 No.4