P168 : Split-face comparison study of new hyaluronic acid filler for efficacy and safety of HA-IDF versus Restylane® for correction of nasolabial folds

( Jie Hyun Jeon ),( Joo Ha Kim ),( Jung Woo Lee ),( Kui Young Park ),( Seong Jun Seo ),( Hae Jun Song ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2

Background: After successive trials and failures of various injectable materials such as bovine collagen, polyacryamide, calcium hydroxylapatite, etc., hyaluronic acid (HA) has become the most popular filling material. Many new HA fillers are being produced for the purpose of correcting wrinkles and augmentation of soft tissue. Objectives: This study aimed to test the efficacy, tolerability, and safety of a new HA filler, HA-IDF (Yvoire Classic s touch-up, LG Life Sciences, Inc., Seoul, South Korea) and compare HA-IDF with Restylane (Q-Med, Uppsala, Sweden). Methods: Fifty-eight subjects with visible nasolabial folds (NLFs) were enrolled in a randomized, multi-center, single-blind, active-controlled, matched-pair clinical study. Each subject was injected with HA-IDF in one NLF and Restylane in the other. All participants were assessed for cosmetic change at 2, 10, 18, and 26 weeks. Results: At screening, the average Wrinkle Severity Rating Scale (WSRS) for both right and left NLFs was 3.24±0.43. After 26 weeks, the results were 2.56±0.09 for both groups. There was no significant difference in WSRS scores for wrinkle improvement and in incidence of adverse events for both HA filler treatments. Conclusion: The new HA filler HA-IDF is effective and safe for correcting NLFs.

Evaluation of Agronomic Stability of North Korean Rice Varieties using Statistical Models

O-Young Jeong,Jeom-Ho Lee,Ha-Cheol Hong,Eung-Gi Jeong,Jin-Soo Paek,Chang-Ihn Yang,Yong-Hee Jeon,Myeong-Ki Kim,Kyu-Seong Lee,Sae-Jun Yang,Young-Tae Lee 韓國作物學會 2008 한국작물학회지 Vol.53 No.1

This experiment was carried out to evaluate the agronomic stability of North Korean rice varieties using the statistical model developed by Grafius, Finlay, and Ever hart. The lowest yearly variation based on coefficients of variation was found in Hannam 29 for number of panicles per hill, in Sijoong 9 for number of grains per panicle, in Pyeongyang 3 for ripened grain ratio, in Sijoong 16 for 1,000 grain weight, and in Yeomju 1 for grain yield. By Grafius's model, Pyeongbook 3, Weonsan 66 in early maturing groups and Seohaechalbyeo in medium maturing groups show stable for 3 years. Weonsan 66 in early maturing groups and Seohaechalbyeo in medium maturing groups were found to be highly stable as analyzed by both Finlay and Wilkinson's model and Everhart & Russell's model. With reference to three models, Weonsan 66 was highly stable for 3 years with showing more yield than Odaebyeo in early maturing groups while Seohaechalbyeo was highly stable for 3 years with showing high yield than Hwaseongbyeo in medium maturing groups above 5~;t~;ha-1 of milled rice respectively.

Evaluation of Agronomic Stability of North Korean Rice Varieties using Statistical Models

Jeong, O-Young,Lee, Jeom-Ho,Hong, Ha-Cheol,Jeong, Eung-Gi,Paek, Jin-Soo,Yang, Chang-Ihn,Jeon, Yong-Hee,Kim, Myeong-Ki,Lee, Kyu-Seong,Yang, Sae-Jun,Lee, Young-Tae The Korean Society of Crop Science 2008 한국작물학회지 Vol.53 No.1

This experiment was carried out to evaluate the agronomic stability of North Korean rice varieties using the statistical model developed by Grafius, Finlay, and Ever hart. The lowest yearly variation based on coefficients of variation was found in Hannam 29 for number of panicles per hill, in Sijoong 9 for number of grains per panicle, in Pyeongyang 3 for ripened grain ratio, in Sijoong 16 for 1,000 grain weight, and in Yeomju 1 for grain yield. By Grafius's model, Pyeongbook 3, Weonsan 66 in early maturing groups and Seohaechalbyeo in medium maturing groups show stable for 3 years. Weonsan 66 in early maturing groups and Seohaechalbyeo in medium maturing groups were found to be highly stable as analyzed by both Finlay and Wilkinson's model and Everhart & Russell's model. With reference to three models, Weonsan 66 was highly stable for 3 years with showing more yield than Odaebyeo in early maturing groups while Seohaechalbyeo was highly stable for 3 years with showing high yield than Hwaseongbyeo in medium maturing groups above $5\;t\;ha^{-1}$ of milled rice respectively.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

남자 평행봉 경기기술의 가치점 및 완성도와 득점의 관계연구

하영준,이승태 仁荷大學校 스포츠科學硏究所 2001 論文集 Vol.13 No.-

The purpose of this thesis is to provide data which hereafter can increase the competing ability in parallel bars for Korean male gymnasts by analyzing performance composition and values parts and degree of perfection of performance of 8 gymnasts who were entrants in the 3rd games (the final by events) of the 34th World Championship Gymnastic Series held in Tan-jen, China from October 11, 1999 to October 16, 1999. I studied the relations between scoring of each performance and total points using SPSS Program, and the conclusion of this analysis was as follows. 1.In total 5 scoring items of performance, connection bonus and degree of perfection exerted a beneficial influence upon total points, and the others had a bad effect on scoring. (p < .05 ) 2.In aquisition of higher total points, degree of perfection exerted the first influence, connection bonus - the second, and the demerit mark of performance - the third. 3.The type of degree of difficulty didn't ever exert any influence upon acquisition of connection bonus. 4.The demerit mark of performance has nothing to do with the demerit of the type of mistakes.

FDM에서 경사면의 표면과 면적오차법의 관계에 대한 연구

전재억,정진서,황영모,김수광,김준안,계중읍,하만경 한국공작기계학회 2002 한국공작기계학회 추계학술대회논문집 Vol.2002 No.-

In any rapid prototyping process, the layer by layer building process introduces an area error between the staircase and the surface line specified by the computer-aided design model. This affects the dimensional accuracy as well as the surface finish for different part build orientations. This paper describes a methodology for computing the area error for any orientation of the part built by the fused deposition modelling system. This technique can be applied to determine the best build orientation of the part, based on the minimum area error. This technique is verified by comparing the results with the experimental measurements of the area error of the parts built at different orientations.

운동학습 귀인에 대한 피드백 유형별의 앞구르기 학습효과 분석

하영준,김진규 仁荷大學校 스포츠科學硏究所 2001 論文集 Vol.13 No.-

The purpose of the study is to clarify the effect of feedbacks(non-feedback, positive feedback and negative feedback) on middle school girls' forward rolling learning by attribution factors(ability, efforts, luck, colleagues and difficulty). 465 girls of P and Y middle schools in Incheon were selected as the experiment target by simple random sampling. A survey on attribution of motor learning was conducted first. Subjects were classified into 3 groups who had a same attribution and who had similar past leaming abilities. During the total of 3 trials, every learner received feedbacks after each trials and after 3 times of trials, every was measured by the survey as well. The mean and the standard deviation was computed as measuring source. To verify the hypothesis, pearson's correlation and Anova, the subordinate program of SPSS, were used and Scheffe was used as a posthumous verification and the result is as follows; 1. Raising the level of attributions to the factor of difficulty and the other factors was significant in improving forward rolling. (p<.05) 2. As an attribution, as for difficulty factor, providing a positive feedback was more efficient than not providing it(p<.05), and as for the other factors, not providing feedback was more efficient than providing positive feedbacks (p<.05) 3. The improvement rate was the lowest in students who take the learning attribution as an ability factor, and other groups showed similar improvement rates (p<.05).

全身持久性 測定方法에 對한 硏究

河永俊 仁荷大學校 스포츠科學硏究所 1991 論文集 Vol.3 No.-

The purpose of this study was to investigate validity, reliability, objectivity and superiority on longrun and steptest for measurements of wholebody endurance. The subjects were selected 66 male athletes by random sampling in INHA Univ. athletes. Items of measurement were VO₂max, VO₂max/kg and ? used by Bicycle erogometer and Heart checker system, longrun(100m) time and steptest index, The validity & reliability of experimental proceeding was evaluated a correlation(pearson) between 5 factors, and factor analysis in spssx is used for analysis of superiority on 5 items. The conclusion was as follows , 1. These is a significant correlation between longrun and VO₂max/Kg and in care of orthers is not 2. There is a significant correlation between steptest and VO₂max/Kg or ? and in care of others is not. 3. In order of superiority on 5 methods, the first is VO₂max/Kg, the second is ?, the third is VO₂max, the forth is steptest, the last is longrun.

비납솔더를 이용한 솔더접합부의 신뢰성에 관한 연구

하범용,이준환,윤준호,신영의 중앙대학교 기술과학연구소 2000 기술과학연구소 논문집 Vol.30 No.-

본 연구에선 실제적으로 전자 제품에 사용되고 있는 패키지(QFP : 피치간격 0.8mm, TSOP : 피치간격 0.4mm)를 사용하여 Sn/Ag 공정 솔더 페이스트를 사용하여 온도 조건에 따른 솔더 접합부의 초기 접합 강도를 45°Peel test를 통해 측정하였으며, Aging시간을 변수로 하여 솔더와 구리 합금 사이에서 생성되는 IMC층의 두께를 측정, 분석하여 Sn/Pb 공정 솔더 페이스트를 사용했을 경우와 비교, 검토하였다. 실험결과로부터 비납솔더인 Sn/Ag 공정 솔더를 사용하여 접합부의 품질 및 장기신뢰성(고온유지) 측면에서 만족할만한 결과를 얻었으며, Sn/Pb 공정솔더의 대체 재료 가능성을 실험을 통하여 입증하였다. As solder joint become small and fine, the reliability and solderability of solder joint is the critical issue in present electronic packaging industry. Besides the use of lead(Pb) containing solders for the interconnections of microelectronic subsytem assembly and packaging has enviromental issue. In this study, using Sn/Pb and Sn/Ag eutectic solder paste, to obtain decrease of solder joint strength with aging time, initial solder joint strength and aging strength after 1000 hour aging at 100℃ were measured by peel test. And to obtain the growth of intermetallic compound(IMC) layer thickness, IMC layer thickness was measured by scanning electron microscope(SEM). As a result, solder joint strength was decrease with aging time increasing. The mean IMC layer thickness was increased linearly with the square root of aging time. The diffusion coefficient(D) of IMC layer was found to 1.29×10 exp (-13) ㎠/s at using Sn/Pb solder paste, 7.56×10 exp (14) ㎠/s at using Sn/Ag solder paste.

排球競技에서 中央攻擊과 左右攻擊이 勝敗에 미치는 影響

河永俊,金明鎭 仁荷大學校 스포츠科學硏究所 1991 論文集 Vol.3 No.-

The purpose of this study was to investigate the effect of the center and side attack on the win and lose, gain and lose point, gain and lose set. The subjects were 68 games in 7th president cup volleyball tournament. The attack style was divided into two(the side and center) attack. The result of attack was divided into 11 sections as follows; (side-SSPP, SSSP, SEPP, SRTP, SAVP, canter- CSPP, CSSP, CEPP, CESP, CRTP, CACP). Regression and t-test were used for analysis of the data. The results were obtained as follows : 1. Win team is significance difference mean more than lose team in CSPP, CSSP, SSPP, but CEPP, SEPP are less than lose team. 2. The effect order of the gain point is SSPP, CEPP, CESP, CSPP, SEPP. 3. The effect order of the gain set are SSPP, CEPP, CSSP, SEPP, BETP, CSPP, CESP, SSSP 4. The effect order of the lost point are CSSP, SSPP, CESP, BETP. 5. The effect order of the lost set are CSSP, SSSP, SSPP, SESP. 6. The effect order of the ranting are CEPP, SSSP, CSSP.