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      • KCI등재

        그림책을 활용한 반편견 교육활동이 유아의 장애 수용 인식 및 태도에 미치는 영향

        원계선,최일선 국립특수교육원 2004 특수교육연구 Vol.11 No.2

        본 연구의 목적은 그림책을 활용한 반편견 교육프로그램이 만 5세 유아의 장애에 대한 인식 및 태도에 미치는 효과를 밝히는 데 있다. 본 연구의 대상은 이천 시 소재 유치원의 만 5세 일반 유아 50명으로, 실험 집단 유아 25명에게는 그림책을 활용한 반편견 교육활동을, 통제집단 유아 25명에게는 정규 유아교육활동을 시행하였다. 연구결과, 두 집단 유아들 간에 장애인에 대한 상호작용의도, 인식 및 수용태도에 있어서 유의한 차이가 있는 것으로 나타났다. 이는 장애와 관련된 그림책을 선정하여 반편견 교육활동을 시행한 것이 일반 유아들의 장애에 대한 인식과 태도에 긍정적인 영향을 끼친다는 점을 시사한다. This study investigates the effects of the anti-bias program using literature on children's intentions, recognitions and attitudes toward children with disabilities. In this study, the subjects were 50 children without disabilities 5 years old kindergarten children. They were placed to an experimental or a control group, with 25 children in each other. While normal regular program was provided for the control group, the anti-bias program through literature was applied to the experimental group for 4 weeks. Significant differences were showed between the pre and post-test scores in intentions, recognitions and attitudes toward the disabled. This results indicates that the anti-bias program using literature affects positive influences to children's intentions, recognitions and attitudes toward children with disabilities.

      • 五加皮의 效能에 대한 硏究

        최민호,이계복,조규원,박진영,김경수,송정석,한종현 한국전통의학연구소 2003 한국전통의학지 Vol.13 No.1

        The purpose of this study is to measure the changes of regional cerebral blood flow (rCBF) and blood pressure (BP) of Cortex Acanthopanacis in rats, and to determine the effect of Cortex Acanthopanacis on phenylephrine (PE) induced contraction of isolated rat thoracic aorts. The measurement was continually monitored by laser-doppler flowmeter (Transonic Instrument, USA) and pressure transducer (Grass, USA) in anesthetized adult Sprague-Dawley rats through the data acquisition system composed of MacLab and Macintosh computer. Contractile force was measured with force displacement transducer under 1.5 g loading tension. The result of this experiment was as following; 1. Cortex Acanthopanacis did not effect the changes of rCBF and blood pressure significantly. 2. Contractions evoked by phenylephrine were decreased significantly by Cortex Acanthopanacis 3. L-NNA, ODQ, atropine and indomethacin significantly altered the relaxation of Cortex Acanthopanacis. 4. Propranolol did not change the relaxation of Cortex Acanthopanacis. These results indicate that Cortex Acanthopanacis did not change the rCBF and BP, but Cortex Acanthopanacis can relax PE induced contraction of isolated rat thoracic aorta and that this increasing contraction related to endothelium and various mechanism.

      • 저가 후막 EL소자 제조 및 신뢰성 평가

        강계원,김대연,이영훈,강봉석,박정현,최병호 금오공과대학교 산업기술개발연구원 2000 産業技術開發硏究 Vol.16 No.-

        AC powder electroluminescence(EL) device consists of seven layers : PET substrate, transparent electrode, phosphor layer, dielectric layer, two layer metal electrodes and protective layer. Etch layer needs to control to improve electrical and optical properties. Both phosphor and dielectric layer among them is more important to increase its properties. For long-time reliability, proper choices of passivation and sealing material are essential. In this paper, influence of phosphor and dielectric layer thickness on EL performance is studied. Type of cellulos is selected as a sealing material to avoid moisture. To add two type of plasticizer to resin improves flexibility and passivation of EL devices. Through this experiments, technologies of fabrication low-cost thick film EL device can be established.

      • 흡착 우라늄 이온의 전기 탈착거동

        정종헌,원휘준,최왕규,김계남,이성호,오원진 한국공업화학회 2003 응용화학 Vol.7 No.1

        Liquid wastes containing uranium ions in high concentration of chemical salts havebeen treated by electrosorption on a activated carbon fibers(ACFs) electrode. Effectiveuranium (VI) removal is accomplished when the potential is -0.5V(vs. Ag/AgCl) ormore negative. For a feed concentration of 100mg/1, the concentration of U(VI) in thecell effluent is reduced to less than 1mg/1, and electrosorption capacity over 500mg/uranium/gACF is reached. The adsorbed uranium can be desorbed up to 99%for 20h by passing a 1.9N NaCl solution at pH 3 through the cell and applying a potential of +1.2V. The amount of desorbed uranium increased as the solution pHwas lowered and the applied potential increased.

      • KCI등재
      • KCI등재

        각질 형성 세포에서 TNF-ɑ로 유도된 염증 반응에 대한 흑삼 추출물의 항염증 효과

        최원영(Won Yeoung Choi),이계원(Gye Won Lee),권득상(Deuk Sang Kwon),신현중(Hyun Joong Shin),조영호(Young Ho Cho) 한국식품영양과학회 2021 한국식품영양과학회지 Vol.50 No.10

        본 연구에서는 85°C에서 9번 증숙한 흑삼 추출물의 총 폴리페놀 함량 및 항산화 활성을 측정하고, TNF-α 유도 피부 각질 형성 세포에서 항염증 효과와 LPS로 유도된 대식세포에서 NO 생성 억제능을 확인하였다. 그 결과 총 폴리페놀 함량은 증숙 전에 비해 증숙 후에 약 2.5배 증가하는 것으로 나타났다. 흑삼 추출물의 항산화 활성을 DPPH, ABTS, superoxide anion 라디칼 소거 활성 및 환원력으로 평가한 결과 증숙 후 흑삼 추출물이 증숙 전에 비해 항산화 활성이 높아지는 것으로 나타났다. Mouse 대식세포인 Raw 264.7 세포에 LPS를 처리한 후 NO 생성량을 확인한 결과 증숙 후 흑삼 추출물의 경우 LPS 단독 처리군에 비해 NO 생성량을 농도 의존적으로 감소시켰다(P<0.001). NO 생성량 감소에 따라 TNF-α로 자극된 피부 각질 형성 세포에서 친염증성 사이토카인인 IL-6, IL-1β 및 IL-8의 mRNA 발현량을 확인한 결과, 흑삼 추출물의 농도 50과 100 μg/mL에서 IL-6의 mRNA 발현을 TNF-α 처리군 대비 약 20% 감소시켰으며 IL-1β와 IL-8의 발현은 농도 의존적으로 감소시키는 것으로 나타났다. 흑삼 추출물이 친염증성 사이토카인의 유전자 발현을 감소시키는 것으로 나타났기 때문에 흑삼 추출물의 항염증 작용을 규명하기 위하여 염증신호전달에 관여하는 전사인자인 NF-κB와 염증 반응을 유도하는 단백질 중 하나인 iNOS와 COX-2 발현에 미치는 영향을 측정하였다. 그 결과 흑삼 추출물 처리 시 TNF-α 처리에 의해 증가된 NF-κB의 인산화와 염증 반응매개물질인 iNOS 및 COX-2의 발현을 유의적으로 감소시키는 것으로 확인되었다(P< 0.001). 이러한 흑삼 추출물의 항염증 효과는 NF-κB의 인산화 억제를 통해 염증 매개 분자의 발현을 감소시켜 친염증성 사이토카인의 생성을 억제하여 나타나는 것으로 확인되었다. 따라서 흑삼 추출물은 피부 염증 개선을 위한 관련 제품의 소재로 활용이 가능할 것으로 기대된다. We evaluated the antioxidant activity and anti-inflammatory effects of black ginseng manufactured by a steaming process in a cell-based inflammatory model. Free radical (DPPH, ABTS, superoxide anion) scavenging activity, reducing power, and total polyphenol content in the extracts of ginseng and black ginseng were investigated. The total polyphenol content of the black ginseng extract was 38.83±1.01 mg/g, which was 2.5 times higher than that of the ginseng extract. Also, the black ginseng extract showed higher free radical scavenging activity than the ginseng extract. The anti-inflammatory effect on lipopolysaccharide (LPS, 50 ng/mL)-induced inflammatory reactions in RAW 264.7 cells demonstrated that treatment with black ginseng extract decreased nitric oxide (NO) and inducible nitric oxide synthase (iNOS) production in a dose-dependent manner (P<0.001). The quantitative RT-PCR result indicated that the black ginseng extract markedly reduced the expression of pro-inflammatory cytokines (interleukin (IL)-6, IL-1β, and IL-8) mRNA in tumor necrosis factor (TNF)-α-treated human keratinocytes. Furthermore, the reduced mRNA expression was associated with the downregulation of iNOS, cyclooxygenase (COX)-2, and nuclear factor (NF)-κB activity. These results suggest that black ginseng extract exhibits anti-inflammatory effects by the downregulation of NF-κB and the consequent suppression of inflammatory mediators (iNOS and COX-2) in TNF-α-induced human keratinocytes and suppression of NO production in LPS-induced murine macrophages. Taken together, these results indicate that black ginseng extract could be a valuable anti-inflammatory agent in products used to treat skin inflammation.

      • KCI등재

        The Development and Performance Evaluation of a Cyclone to Remove Hot Particulate from a Contaminated Hot Cell

        Gye-Nam Kim,Hui-Jun Won,Wang-Kyu Choi,Chong-Hun Jung,Won Jin Oh,Jin Ho Park 한국방사성폐기물학회 2006 방사성폐기물학회지 Vol.4 No.3

        원자력연구소 핫셀의 구조와 오염특성이 조사되었다. SEM 측정결과 핫셀 내부에 부착된 고방사능 분진의 크기는 이었다. 사이클론의 최적 Vortex finder의 길이는 49 mm이고, 모의입자 유입속도는 15m/sec가 적합했다. 이때 의 포집효율은 약 85%였다. 모의 입자 유입속도가 15m/sec보다 빠를 때, 포집효율의 증가율은 크지 않았다. 유입가스의 온도가 증가할 때, 포집효율은 약간 감소했다. Vortex finder의 길이가 증가할수록 사이클론내의 압력강하는 커졌다. Cut size diameter는 Reynolds number의 증가와 함께 감소했다. 측정된 Reynolds number에 근거하면, 사이클론 내부는 난류이고 이 난류는 사이클론 내의 압력강하에 원인이 된다고 사료된다. 는 Re 값의 증가와 함께 감소하고, Re의 값이 커질 때에서 일정한 값에 수렴했다. 즉, 6000-8000의 Re에서 는 약 0.045를 나타냈다. The structural and contamination characteristics of hot cells at KAERI were investigated. The SEM results showed that the size of the hot particulate on the inner surface of the hot cell ranged from 0.2 to . It was found that an inlet flow rate of 15 m/sec was suitable for this developed cyclone with a 49 mm optimum vortex finder length. The results showed that the collection efficiency was about 85% for particles. The collection efficiency didn't show a sharp increase when the inlet flow rate was faster than 15m/sec. When the temperature of the inlet flow gas was increased, the collection efficiency of the cyclone was slightly decreased. The larger the vortex finder length was, the higher the pressure drop in the cyclone was. The cut size diameter decreased with an increment of the Reynolds number. It was established that the flow in the cyclone was a turbulent flow on the basis of the Reynolds number and this turbulent flow caused a pressure drop in the cyclone. decreased with increasing values of the Reynolds number and it gradually approached a constant value at a higher value of the Reynolds number Namely, approached approximately 0.045 between 6000 and 8000 of the Reynolds number.

      • State-of-the-art of Pier Scour Prediction for Design Application

        Choi, Gye-Woon,Ahn, Sang-Jin,Kang, Kwan-Won Korea Water Resources Association 1991 Korean journal of hydrosciences Vol.2 No.-

        Scour at bridge pier is a complicated three-dimensional problem involving interaction of fluld force on movable aid nonuniformily distributed sand grains. Although several analytical solution approaches, experimental research and field investigations for scout at piers have been conducted, no comprehensive and universally acceptable solution is so far available. Even though many methods and equations for predicting scour at piers are available in the literature, hydraulic and/or bridge design engineers are often at a loss over which method or equation is applicable for the specific bridge sites. To provide better understanding about scour phenomena and better predicting of scour at piers, intensive research is conducted through comprehensive review of published literature. Based on the research the state-of-the-art of pier scour prediction for design application is provided as a design guide for practicing engineers in this field. Recommendations for applying aggradation and degradation, contraction scour, and local scour prediction methods or equations are suggested. It is hoped that this paper may provide good information for the prediction of scour at piers.

      • Fractal fluctuations in spatiotemporal variables when walking on a self-paced treadmill

        Choi, Jin-Seung,Kang, Dong-Won,Seo, Jeong-Woo,Tack, Gye-Rae Elsevier 2017 Journal of biomechanics Vol.65 No.-

        <P><B>Abstract</B></P> <P>This study investigated the fractal dynamic properties of stride time (ST), stride length (SL) and stride speed (SS) during walking on a self-paced treadmill (STM) in which the belt speed is automatically controlled by the walking speed. Twelve healthy young subjects participated in the study. The subjects walked at their preferred walking speed under four conditions: STM, STM with a metronome (STM+met), fixed-speed (conventional) treadmill (FTM), and FTM with a metronome (FTM+met). To compare the fractal dynamics between conditions, the mean, variability, and fractal dynamics of ST, SL, and SS were compared. Moreover, the relationship among the variables was examined under each walking condition using three types of surrogates. The mean values of all variables did not differ between the two treadmills, and the variability of all variables was generally larger for STM than for FTM. The use of a metronome resulted in a decrease in variability in ST and SS for all conditions. The fractal dynamic characteristics of SS were maintained with STM, in contrast to FTM, and only the fractal dynamic characteristics of ST disappeared when using a metronome. In addition, the fractal dynamic patterns of the cross-correlated surrogate results were identical to those of all variables for the two treadmills. In terms of the fractal dynamic properties, STM walking was generally closer to overground walking than FTM walking. Although further research is needed, the present results will be useful in research on gait fractal dynamics and rehabilitation.</P>

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