Systemic Lupus Erythematosus를 동반한 Multiple sclerosis

이지현,이기주,윤성호,부귀범,손현화,박유환,정춘해,김진호,정원영 조선대학교 부설 의학연구소 1998 The Medical Journal of Chosun University Vol.23 No.2

Multiple sclerosis and lupus erythematosus are chronic, potentially disabling diseases of unknown cause. It is a rare occasion that the finding of both diseases occurs in one patient. Because both diseases may affect the central nervous system, it may be difficult at times to differentiate symptoms of lupus erythematosus from those of multiple sclerosis. As far as we know, there was no case report of SLE in multilple sclerosis in Korea. We report a case of multiple sclerosis accompanied by SLE.

경량 콘크리트를 이용한 온돌 바닥층의 열적 특성 : 진공관형 태양열집열기를 이용한 자갈의 현열축열 특성 Characteristics of sensible heat storage for gravel using evacuated glass tube solar collector

이귀현,구재오 강원대학교 부설 석재복합신소재 제품연구센터 2003 석재연 논문집 Vol.8 No.-

본 연구에서는 공기 가열을 위해 진공관형 태양열집열기를 이용하여 3종류의 자갈에 대한 현열축열 특성을 조사하였다. 74.8%의 집 열효율을 갖는 태양열집열기 내에서 가열된 공기는 자갈로 채워진 죽열조내로 순환되고, 축열조 내의 자갈층에 열을 전달시킨 공기는 다시 집열기로 유입된다. 여기서, 집열기에 의해 가열된 공기의 열을 자갈층에 저장시키기 위한 축열실험은 480분 동안 지속되었다. 자갈의 크기가 열저장 효율에 미치는 영향을 조사하기 위해 축열실험 동안 축열조내의 상ㆍ중ㆍ하부 3위치에서 공기온도를 측정하였다. 제 1ㆍ2ㆍ3종 자갈로 구성된 축열조내 상ㆍ중ㆍ하단부의 평균 공기온도는 축열실험 전보다 각각 6℃, 5.7℃, 5.5℃ 상승한 것으로 나타났다. 즉, 작은 자갈의 축열조내 평균 공기온도 상승이 큰 자갈의 축열조 보다 낮았다. 이것은 작은 자갈일수록 큰 자갈보다 많은 열에너지를 자갈층에 저장하게 됨으로 자갈 주위의 공기온도를 낮게 하였기 때문인 것으로 사료된다. 그러므로 큰 자갈에 비해 작은 자갈일수록 축열조내의 공극이 작고 비중량이 클 뿐만 아니라 열용량이 커 축열 매체로서 매우 유리하게 사용될 수 있을 것으로 판단된다. In this study, the characteristics of sensible heat storage for three kinds of gravel were investigated with using evacuated glass tube solar collector for heating air. Air heated inside the solar collector with heat collecting efficiency of 74.8% was circulated into the heat storage system packed with gravel. After storing heat to gravel inside the heat storage system, air was again circulated into solar collector. An experiment for storing heat from air heated by solar collector to gravel of the heat storage system was repeated for 480min. Temperatures at the bottom, middle, and top positions of heat storage system were monitored to investigate the effect of gravel size on storing heat. Average air temperature of the bottom, middle, and top positions of heat storage system for each 1st, 2nd, and 3rd kind of gravel were increased 6.0, 5.7, and 5.5℃ respectively. Increase of air temperature inside the heat storage system with the smaller size of gravel was lower than that of larger size of gravel. It was suggested that heat was more consumed for storing into smaller size of gravel than that of larger size lowering air temperature around the gravel. Thus, smaller size of gravel is better than that of larger size on storing heat because of its great heat capacity with low porosity of heat storage system and large specific weight of gravel.

석재 신소재를 이용한 조립식 온돌패널 개발 : 자갈 축열시스템 성능 분석 Analysis of the Performance of Heat-Storage System Packed with Gravel

이귀현,구재오 강원대학교 부설 석재복합신소재 제품연구센터 2002 석재연 논문집 Vol.7 No.-

본 연구에서는 크기가 서로 다른 자갈로 이루어진 3종류의 축열시스템에 대한 축열성능을 조사하였다. 제1종 자갈을 사용한 축열시스템은 출열조로 공급되는 공기의 온도가 50℃와 62℃ 일 때, 축열조 출구의 공기온도가 33℃에 도달될 때까지 가열되는 축열시간은 각각 170분과 130분이었으며, 출구 공기온도 33℃ 이상을 기준으로 한 열 회수 시간은 각각 100분 및 115분으로 나타났다. 제 2종 자갈을 사용한 축열시스템에 있어서 축열조에 공급되는 공기의 온도가 52℃와 64℃일 때, 축열에 소요된 시간은 각각 175분과 140분이었고, 열 회수에 소요된 시간은 각각 120분 및 140분으로 나타났다. 제 3종 자갈을 사용한 축열시스템은 축열조로 공급되는 공기의 온도가 52℃와 64℃ 일 때, 축열에 소요된 시간은 각각 180분과 150분이었고, 에너지 회수시간은 각각 140분과 160분으로 나타났다. 이와 같이 자갈이 작을수록 축열조 출구의 공기온도가 기준온도 33℃에 도달되는 시간이 길었으며, 이것은 축열조내의 공극이 작고 비중량이 커 자갈층을 가열시키는 축열시간이 길어지기 때문인 것으로 사료된다. 또한 작은 자갈일수록 방열시간도 다소 길어져 회수 가능 열에너지가 큰 것으로 나타났다. In this study, the performance of heat-storage system packed with three kinds of gravel was in investigated. In the heat-storage system with the 1st kind gravel, heating were taken to be 170 and 130 minutes in reaching to air temperature of 33℃ at the exit of the system, when temperatures of an inlet air supplied into the system were 50 and 62℃. Durations for recovering heat stored in gravel were 100 and 115 minutes for each inlet air-temperature of 50 and 62℃, respectively, if air temperature of above 33℃ is usable With the 2nd kind gravel, it was taken to be 175 and 140 minutes for obtaining air temperature. 33℃ at an exit of the system, when heated air of 52 and 64℃ was supplied into the system. In this system, recovery times were each 120 and 140 minutes for supplied air of 52 and 64℃ in with drawing heated air above 33℃ at an exit of the system. In the heat-storage system packed with the 3rd kind gravel, it was taken to be 180 and 150 minutes on heating gravel with supplied air temperature of 52 and 64℃ until the temperature of air at exit of the system was reached to 33℃. In this system, Recovery times of heat were 140 and 160 minutes respectively for supplied air of 52 and 64℃. Generally, it was taken more heating and recovery time in the heat-storage system with smaller size of gravel due to smaller porosity and grater specific weigh of gravel.

황해 직선 황로상 대기오염물질의 측정

이승복,배귀남,진현철,김영성,문길주,심상규 한국대기환경학회 2004 한국대기환경학회지 Vol.20 No.1

Air pollutants were measured eight times from June 1999 to June 2002 on regular ferries cruising across the Yellow Sea between Incheon in Korea and Qingdao or Tianjin in China. PM_(10) and PM_(2.5_ were measured as particulate matters and SO₂, CO, and NOx were measured as gaseous pollutants. On each route, sampling was made, starting two hour after departure and ending two hour before arrival. Low concentrations of gaseous pollutants that were not much varied according to sampling period and location revealed that atmosphere over the sea was not directly affected by anthropogenic emissions. However, concentrations of fine particles were generally higher than those measured at Deokjeok Island. 50 km west of the western seashore, at similar periods. It was believed that considerable influence of China in the form of secondary pollutants was exerted over the sea.

신체적 기능상태에 따른 장애인의 비급여 의료비용 및 추가비용 : 의료보호 장애인을 대상으로 in Medical Aid beneficiaries

이효영,김귀현 대한보건협회 2003 대한보건연구 Vol.29 No.1

This study is to measure the impact of disability on medical cost and additional cost not in Medical Aid allowance. It has three specific aims. The first aim is to identify how much extra expenditure needs in the disable using medical care. The second aim is to examine the relationship between the cost of disability and physical functioning levels of the disabled. The third aim is to examine the difference of medical cost and additional cost by disability level and type. Participants were the 864 subjects who were beneficiaries of National Mdcal aid and lived in 10 areas of Korea. A questionnaire was distributed during August to September 2001 through public offices. Social workers in public office helped this survey and it was conducted to visit the disabled families. Physical function of the disabled was examined by ADL, IADL. Medical cost and additional cost in medical care were examined by one month. The focus of this study is in relationship between physical functioning levels and medical cost and additional cost as a result of disability in medical care. Medical cost and extra expenditure per capita by one month did not increased with poorer physical function. But the cost were different from each physical functioning level, disability level and type. The Reevaluation of Medical Aid allowance range and supports for the disabled person will be enlarged to lessen economic burden of the disabled. Besides the disabled need more medical care and a huge amount of medical resources than non-disabled person. Cost-effective intervention programs for disability prevention urgently need to reduce medical care and its additional cost.

실내 스모그 챔버의 설계 및 성능평가

배귀남,김민철,이승복,송기범,진현철,문길주 한국대기환경학회 2003 한국대기환경학회지 Vol.19 No.4

A multi-functional indoor smog chamber was designed and evaluated lo investigate photochenical or water vapor reaction mechanisms of air pollutants. Various smog chamber experiments could be conducted using ambient air or purified air in this smog chamber. The smog chamber consisted of a housing, a Teflon bag, blacklights, injection ports, sampling ports, and utility facilities. The characteristics of light source, the wall losses of air pollutants, and the quality of purified air were experimentally investigated. The maximum NO₂ photolysis rate was 1.10min^(-1). In a 2.5-m³ Teflon bag, the wall losses of ambient O₃, NO, and NO₂were 1.2~2.4×10^(-3)min^(-1), 0.7~2.0×10^(-3)min^(-1), and 0.4-2.0×10^(-3)min^(-1), respectively. The wall loss of ambient particles ranging 0.05 to 0.2㎛ was 1.8~5.4×10^(-3)min^(-1), which was slightly higher than those of ambient gaseous species. The purified air supply system provided high quality of air with NO₂, < 1 ppb, and total hydrocarbons <5 ppb.

튜브 전기로를 이용한 TiO₂ 나노입자의 합성 및 특성 분석

배귀남,현정은,이태규,정종수 한국대기환경학회 2004 한국대기환경학회지 Vol.20 No.3

Titania particles are widely used as a photocatalyst to treat various contaminants in air and water. Titania particles were formed by vapor-phase oxidation of titanium tetraisopropoxide (TTIP) in a tube furnace between 773 and 1,273 K. The effect of process variables such as furnace temperature. flow rate of carrier air. and flow rate of sheath air on powder size and phase characteristics was investigated using a scanning mobility particle sizer (SMPS), transmission electron microscopy (TEM) and X-ray diffraction (XRD). The size distribution of synthesized titania particles was characterized with mode diameter and peak concentration. The mode diameter ranging from 20 to 80 nm decreased with increasing flow rates of sheath air and carrier air, and increased with increasing furnace temperature. The peak concentration increased with increasing flow rates of sheath air and carrier air. The best synthetic condition for high production rate can be derived from the experimental data set represented by mode diameter and peak concentration. The crystal structure of synthesized titania particles was found to be anatase phase, ensuring high photocatalytic potential.

긴볼레기말의 항고지혈증 효과에 관한 연구 : Triton WR-1339 주사에 의한 고지혈증 유발 생쥐의 간세포내 지방 축적 감소를 중심으로 Based on the Decreasing Effect of Lipid Accumulation in Hepatocyte of Murine with Hyperlipidemia induced by Triton WR-1339

박인식,안상현,정재만,강윤호,이해풍,서귀문,홍용기,김호현,김진택 동국대학교 한의학연구소 1999 東國韓醫學硏究所論文集 Vol.7 No.2

본 연구는 긴볼레기말 추출물의 항고지혈증 효과를 조사하기 위해 ICR 생쥐에 TritonWR-1339(TX) 복강주사로 인위적인 고지혈증을 유발시킨 후 긴볼레기말 추출물(30㎎/㎏)를 복강주사하여 시간의 경과에 따른 간세포내에서의 지방 축적 변화를 조직화학적으로 관찰하였다. TX 주사후 그물구조의 세포질출 가진 간세포가 간엽 전체에서 관찰되었고, 일부 간소엽에서는 간세포 손상으로 인한 간세포판 소실이 나타났다. 또한 간세포내 지방축척도 증가하여 전체 간소엽의 간세포에서 지방의 과출현을 확인 할 수 있었고, 지방의 크기도 대조군에 비해 증가된 것으로 관찰되었다. 그러나 긴볼레기말 추출물 주사군에서는 그물구조의 세포질을 가진 간세포의 수가 TX 주사군에 비해 감소되었고, 대부분의 간소엽에서 정상적인 간세포판의 배열을 확인할 수 있었다. 간세포내의 지방 축적과 크기도 감소된 경향으로 관찰되었다. 이상의 결과로 볼 때 해조류 긴볼레기말 추출물은 고지혈증이 유발된 생쥐 간세포 내에서의 과도한 지방축적을 감소시키는 항고지혈증 효과를 하는 것으로 사료된다. Hepatic tissues of ICR mouse were intraperitoneally injeced with Colpomenia bullosa(CB) Extract after Triton WR-1339(TX) injection were observed to investigate the antihyperlipermic effect of CB extract for hyperlipidemic hepatic tissue caused by destruction of lipid metabolism. The hepatic tissues were obtained at hour-24, 48, and 72 after TX injection with CB extract treatment. And then these specimen were fixed in 10% neutral buffer solution and were cryocut. The tissue stained by H&E for general morphology and sudan black B for lipid distribution. The increase of hepatocyte having rneshlike cytoplasm were shown in all hepatic lobules after TX injection and the hepatic plates were disappeared in the region of meshlike hepatocyte aggregation, But the hepatocyte having meshlike cytoplasm were disappeared and hapatic plate were rearranged in CB extract injected mouse. The number of blue black colored lipid drop in hepatic cytoplasm of mouse injected with TX were increased and the size of lipid drop were enlarged. But the number of lipid drop in hepatic cytoplasm of mouse treated CB extract were decreased and the size of lipid drop were diminished. As results indicated that the accumulation of lipid drop caused by TX injection were mitigated by the antihyperlipidermic effect of CB extract.

Protective effect of <i>cirsimaritin</i> against streptozotocin-induced apoptosis in pancreatic beta cells

Lee, Dahae,Kim, Ki Hyun,Lee, Jaemin,Hwang, Gwi Seo,Lee, Hye Lim,Hahm, Dae-Hyun,Huh, Chang Ki,Lee, Sang Cheon,Lee, Sanghyun,Kang, Ki Sung Pharmaceutical Society of Great Britain 2017 Journal of pharmacy and pharmacology Vol.69 No.7

Drying Characteristics of Carrot and Green Pumpkin Slices in Waste Heat Dryer

( Gwi Hyun Lee ) 한국농업기계학회 2012 바이오시스템공학 Vol.37 No.1

Purpose: Drying characteristics of the sliced carrot and green pumpkin were investigated by using the waste heat dryer. Methods: The effects of drying temperature (T) and slice thickness affecting drying time were analyzed. Mathematical models for the drying curves were determined with statistical analysis of drying data. Effective diffusivity was determined for the slices of carrot and green pumpkin under various drying conditions. Results: Drying time was reduced at the drying conditions of thinner slice and higher drying temperature. Moisture ratio (MR) according to drying time (t) was well presented as an exponential function at all of drying conditions for the slices of carrot and green pumpkin with the determination coefficient (r2) of >0.99. The values of effective diffusivity (Dff) of the slices for carrot and green pumpkin were increased with increasing the drying temperature. The relationship between Ln(Dff) and 1/T was linear with the determination coefficient (r2) of >0.97. Conclusions: Drying model was well established as an exponential function at all of drying conditions for drying samples.