Experimental behaviours of steel tube confined concrete (STCC) columns

Guo-Huang Yao,Qing Yu,Lin-Hai Han,Zhi-Bo Chen 국제구조공학회 2005 Steel and Composite Structures, An International J Vol.5 No.6

In recent years, the use of steel tube confined concrete (STCC) columns has been the interests of many structural engineers. The present study is an attempt to study the monotonic and cyclic behaviours of STCC columns. For the monotonic behaviours, a series of tests on STCC stub columns (twenty one), and beam-columns (twenty) were carried out. The main parameters varied in the tests are: (1) column section types, circular and square; (2) tube diameter (or width) to thickness ratio, from 40 to 162, and (3) load eccentricity ratio (e/r), from 0 to 0.5. For the cyclic behaviours, the test parameters included the sectional types and the axial load level (n). Twelve STCC column specimens, including 6 specimens with circular sections and 6 specimens with square sections were tested under constant axial load and cyclically increasing flexural loading. Comparisons are made with predicted column strengths and flexural stiffness using the existing codes. It was found that STCC columns exhibit very high levels of energy dissipation and ductility, particularly when subjected to high axial loads. Generally, the energy dissipation ability of the columns with circular sections was much higher than those of the specimens with square sections. Comparisons are made with predicted column strengths and flexural stiffness using the existing codes such as AIJ-1997, AISCLRFD- 1994, BS5400-1979 and EC4-1994.

Mechanical behavior of rock-coal-rock specimens with different coal thicknesses

Guo, Wei-Yao,Tan, Yun-Liang,Yu, Feng-Hai,Zhao, Tong-Bin,Hu, Shan-Chao,Huang, Dong-Mei,Qin, Zhe Techno-Press 2018 Geomechanics & engineering Vol.15 No.4

To explore the influence of coal thickness on the mechanical behavior and the failure characteristics of rock-coal-rock (RCR) mass, the experimental investigation of uniaxial compressive tests was conducted first and then a systematic numerical simulation by particle flow code (PFC2D) was performed to deeply analyze the failure mechanical behavior of RCR specimens with different coal thicknesses in conventional compression tests. The overall elastic modulus and peak stress of RCR specimens lie between the rock and the coal. Inter-particle properties were calibrated to match the physical sample strength and the stiffness response. Numerical simulation results show that the deformation and strength behaviors of RCR specimens depend not only on the coal thickness, but also on the confining pressure. Under low confining pressures, the overall failure mechanism of RCR specimen is the serious damage of coal section when the coal thickness is smaller than 30 mm, but it is shear failure of coal section when the coal thickness is larger than 30 mm. Whereas under high confining pressures, obvious shear bands exist in both the coal section and the rock section when the coal thickness is larger than 30 mm, but when the coal thickness is smaller than 30mm, the failure mechanism is serious damage of coal section and shear failure of rock section.

Design and analysis of an origami-inspired deployable grasping manipulator

Xin Guo,Changqing Gao,Hailin Huang,Bing Li,Yingxue Yao,Guanglu Jia 한국생산제조학회 2018 한국생산제조시스템학회 학술발표대회 논문집 Vol.2018 No.10

Fumigaclavine C attenuates adipogenesis in 3T3-L1 adipocytes and ameliorates lipid accumulation in high-fat diet-induced obese mice

Wan-Guo Yu,Yun He,Yun-Fang Chen,Xiao-Yao Gao,Wan-E Ning,Chun-You Liu,Ting-Fan Tang,Quan Liu,Xiao-Cheng Huang 대한약리학회 2019 The Korean Journal of Physiology & Pharmacology Vol.23 No.3

Fumigaclavine C (FC), an active indole alkaloid, is obtained from endophytic Aspergillus terreus (strain No. FC118) by the root of Rhizophora stylosa (Rhizophoraceae). This study is designed to evaluate whether FC has anti-adipogenic effects in 3T3-L1 adipocytes and whether it ameliorates lipid accumulation in highfat diet (HFD)-induced obese mice. FC notably increased the levels of glycerol in the culture supernatants and markedly reduced lipid accumulation in 3T3-L1 adipocytes. FC differentially inhibited the expressions of adipogenesis-related genes, including the peroxisome proliferator-activated receptor proteins, CCAAT/enhancer-binding proteins, and sterol regulatory element-binding proteins. FC markedly reduced the expressions of lipid synthesis-related genes, such as the fatty acid binding protein, lipoprotein lipase, and fatty acid synthase. Furthermore, FC significantly increased the expressions of lipolysis-related genes, such as the hormone-sensitive lipase, Aquaporin- 7, and adipose triglyceride lipase. In HFD-induced obese mice, intraperitoneal injections of FC decreased both the body weight and visceral adipose tissue weight. FC administration significantly reduced lipid accumulation. Moreover, FC could dosedependently and differentially regulate the expressions of lipid metabolism-related transcription factors. All these data indicated that FC exhibited anti-obesity effects through modulating adipogenesis and lipolysis.

Fumigaclavine C attenuates adipogenesis in 3T3-L1 adipocytes and ameliorates lipid accumulation in high-fat diet-induced obese mice

Yu, Wan-Guo,He, Yun,Chen, Yun-Fang,Gao, Xiao-Yao,Ning, Wan-E,Liu, Chun-You,Tang, Ting-Fan,Liu, Quan,Huang, Xiao-Cheng The Korean Society of Pharmacology 2019 The Korean Journal of Physiology & Pharmacology Vol.23 No.3

Fumigaclavine C (FC), an active indole alkaloid, is obtained from endophytic Aspergillus terreus (strain No. FC118) by the root of Rhizophora stylosa (Rhizophoraceae). This study is designed to evaluate whether FC has anti-adipogenic effects in 3T3-L1 adipocytes and whether it ameliorates lipid accumulation in high-fat diet (HFD)-induced obese mice. FC notably increased the levels of glycerol in the culture supernatants and markedly reduced lipid accumulation in 3T3-L1 adipocytes. FC differentially inhibited the expressions of adipogenesis-related genes, including the peroxisome proliferator-activated receptor proteins, CCAAT/enhancer-binding proteins, and sterol regulatory element-binding proteins. FC markedly reduced the expressions of lipid synthesis-related genes, such as the fatty acid binding protein, lipoprotein lipase, and fatty acid synthase. Furthermore, FC significantly increased the expressions of lipolysis-related genes, such as the hormone-sensitive lipase, Aquaporin-7, and adipose triglyceride lipase. In HFD-induced obese mice, intraperitoneal injections of FC decreased both the body weight and visceral adipose tissue weight. FC administration significantly reduced lipid accumulation. Moreover, FC could dose-dependently and differentially regulate the expressions of lipid metabolism-related transcription factors. All these data indicated that FC exhibited anti-obesity effects through modulating adipogenesis and lipolysis.

Analysis of a photonic crystal fiber sensor with reuleaux triangle

Pibin Bing,Shichao Huang,Xinyue Guo,Hongtao Zhang,Lian Tan,Zhongyang Li,Jianquan Yao 한국광학회 2019 Current Optics and Photonics Vol.3 No.3

The characteristics of a photonic crystal fiber sensor with reuleaux triangle are studied by using the finite element method. The wavelength sensitivity of the designed optical fiber sensor is related to the arc radius of the reuleaux triangle. Whether the core area is solid or liquid as well as the refractive index of the liquid core contributes to wavelength sensitivity. The simulation results show that larger arc radius leads to higher sensitivity. The sensitivity can be improved by introducing a liquid core, and higher wavelength sensitivity can be achieved with a lower refractive index liquid core. In addition, the specific channel plated with gold film is polished and then analyte is deposited on the film surface, in which case the position of the resonance peak is the same as that of the complete photonic crystal fiber with three analyte channels being filled with analyte. This means that filling process becomes convenient with equivalent performance of designed sensor. The maximum wavelength sensitivity of the sensor is 10200 nm/RIU and the resolution is 9.8 × 10 -6 RIU.

Probiotics Increase Intramuscular Fat and Improve the Composition of Fatty Acids in Sunit Sheep through the Adenosine 5′-Monophosphate-Activated Protein Kinase (AMPK) Signaling Pathway

Yue Zhang,Duo Yao,Huan Huang,Min Zhang,Lina Sun,Lin Su,LiHua Zhao,Yueying Guo,Ye Jin 한국축산식품학회 2023 한국축산식품학회지 Vol.43 No.5

This experiment aims to investigate the impact of probiotic feed on growth performance, carcass traits, plasma lipid biochemical parameters, intramuscular fat and triglyceride content, fatty acid composition, mRNA expression levels of genes related to lipid metabolism, and the activity of the enzyme in Sunit sheep. In this experiment, 12 of 96 randomly selected Sunit sheep were assigned to receive the basic diet or the basic diet supplemented with probiotics. The results showed that supplementation with probiotics significantly increased the loin eye area, and decreased plasma triglycerides and free fatty acids, increasing the content of intramuscular fat and triglycerides in the muscle and improving the composition of the fatty acids. The inclusion of probiotics in the diet reduced the expression of adenosine 5’-monophosphate-activated protein kinase alpha 2 (AMPKα2) mRNA and carnitine palmitoyltransferase 1B (CPT1B) mRNA, while increasing the expression of acetyl-CoA carboxylase alpha (ACCα) mRNA, sterol regulatory elementbinding protein-1c (SREBP-1c) mRNA, fatty acid synthase mRNA, and stearoyl-CoA desaturase 1 mRNA. The results of this study indicate that supplementation with probiotics can regulate fat deposition and improves the composition of fatty acids in Sunit sheep through the signaling pathways AMPK-ACC-CPT1B and AMPK-SREBP-1c. This regulatory mechanism leads to an increase in intramuscular fat content, a restructuring of muscle composition of the fatty acids, and an enhancement of the nutritional value of meat. These findings contribute to a better understanding of the food science of animal resources and provide valuable references for the production of meat of higher nutritional value.

Behavior and calculation on concrete-filled steel CHS (Circular Hollow Section) beam-columns

Lin-Hai Han,Guo-Huang Yao,Xiao-Ling Zhao 국제구조공학회 2004 Steel and Composite Structures, An International J Vol.4 No.3

A mechanics model is developed in this paper for concrete-filled steel CHS (circular hollow section) beam-columns. A unified theory is described where a confinement factor (ξ) is introduced to describe the composite action between the steel tube and the filled concrete. The predicted load versus deformation relationship is in good agreement with test results. The theoretical model was used to investigate the influence of important parameters that determine the ultimate strength of concrete-filled steel CHS beam-columns. The parametric and experimental studies provide information for the development of formulas for the calculation of the ultimate strength of the composite beam-columns. Comparisons are made with predicted beam-columns strengths using the existing codes, such as LRFD-AISC-1999, AIJ-1997, BS5400-1979 and EC4-1994.

Evaluating Permeability and Efficiency of Substrates by Using Permeation Grouting Sand Column Test

Jen-Chen Fan,Wen-Yao Liu,Che-Hsin Liu,Chien-Lin Huang,Yun-Wei Tan,Jia-Jun Guo 대한토목학회 2018 KSCE JOURNAL OF CIVIL ENGINEERING Vol.22 No.8

This study design the sand column tests in the laboratory to evaluate permeability and efficiency of substrates by using permeationgrouting technology. The results show, the coarser the test sand and the lower the substrates viscosity, the better the grouting effect. Ifmore than 5% fines added will affect the grouting results significantly. Spearman’s rank correlation coefficient and stepwiseregression method were applied to analysis 36 sets of sand columns testing results. The relationships among the effective size of testsand (D10), the viscosity of substrates and grouting height, grouting time, grouting rate and outflow rate were obtained. The results ofthis study might be helpful for applying the permeation grouting technology to remedy the contaminated groundwater in the field.

A Novel Photonic Crystal Fiber Sensor with Three D-shaped Holes Based on Surface Plasmon Resonance

Pibin Bing,Jialei Sui,Shichao Huang,Xinyue Guo,Zhongyang Li,Lian Tan,Jianquan Yao 한국광학회 2019 Current Optics and Photonics Vol.3 No.6

A novel photonic crystal fiber (PCF) sensor with three D-shaped holes based on surface plasmon resonance (SPR) is analyzed in this paper. Three D-shaped holes are filled with the analyte, and the gold film is deposited on the side of three planes. The design of D-shaped holes with outward expansion can effectively solve the uniformity problem of metallized nano-coating, it is beneficial to the filling of the analyte and is convenient for real-time measurement of the analyte. Compared with the hexagonal lattice structure, the triangular arrangement of the clad air holes can significantly reduce the transmission loss of light and improve the sensitivity of the sensor. The influences of the air hole diameter, the distance between D-shaped holes and core, and the counterclockwise rotation angle of D-shaped holes on sensing performance are studied. The simulation results show that the wavelength sensitivity of the designed sensor can be as high as 10100 nm/RIU and the resolution can reach 9.9 × 10 -6 RIU.