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An Adaptive JPEG Steganographic Method Based on Weight Distribution for Embedding Costs
( Yi Sun ),( Guangming Tang ),( Yuan Bian ),( Xiaoyu Xu ) 한국인터넷정보학회 2017 KSII Transactions on Internet and Information Syst Vol.11 No.5
Steganographic schemes which are based on minimizing an additive distortion function defined the overall impacts after embedding as the sum of embedding costs for individual image element. However, mutual impacts during embedding are often ignored. In this paper, an adaptive JPEG steganographic method based on weight distribution for embedding costs is proposed. The method takes mutual impacts during embedding in consideration. Firstly, an analysis is made about the factors that affect embedding fluctuations among JPEG coefficients. Then the Distortion Update Strategy (DUS) of updating the distortion costs is proposed, enabling to dynamically update the embedding costs group by group. At last,a kind of adaptive JPEG steganographic algorithm is designed combining with the update strategy and well-known additive distortion function . The experimental result illustrates that the proposed algorithm gains a superior performance in the fight against the current state-of-the-art steganalyzers with high-dimensional features.
A bi-directional valveless piezoelectric micropump based on the Coanda effect
Zheng Zhang,Lipeng He,Jianwen Zhou,Dianbin Hu,Yi Hou,Guangming Cheng 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.2
In this paper, the hydrodynamic characteristics of a piezoelectric micropump operate on the Coanda effect, and the mechanism of bi-directional pumping are analyzed by numerical simulation and experiments. The research focuses on the different positions of the fluid deflector and the influence on the output of the micropump. The results show that a closer fluid deflector to the inlet can produce greater vortices in the suction process due to the Coanda effect, and the backflow diminishing is more significant as well. Moreover, the different positions of the fluid deflector can cause a phenomenon that the micropump will achieve bi-directional pumping. As a finding, vortices arranged in pairs could improve the rectification efficiency of the micropump. The micropump achieves a maximum flow rate of 40.5 ml/min and back pressure of 5.76 cmH 2 o. In addition, the maximum flow rate per unit area can reach 305.2 μl/(min mm 2 ).
Rongxin Liao,Kehong Chen,Jinjin Li,Hengqiu He,Guangming Yi,Mingfeng Huang,Rongrong Chen,Lu Shen,Xiaoyue Zhang,Zaicheng Xu,Zhenzhou Yang,Yuan Peng 대한암학회 2023 Cancer Research and Treatment Vol.55 No.3
Purpose Oligometastatic non–small cell lung cancer (NSCLC) patients have been increasingly regarded as a distinct group that could benefit from local treatment to achieve a better clinical outcome. However, current definitions of oligometastasis are solely numerical, which are imprecise because of ignoring the biological heterogeneity caused by genomic characteristics. Our study aimed to profile the molecular alterations of oligometastatic NSCLC and elucidate its potential difference from polymetastasis. Materials and Methods We performed next-generation sequencing to analyze tumors and paired peripheral blood from 77 oligometastatic and 21 polymetastatic NSCLC patients to reveal their genomic characteristics and assess the genetic heterogeneity. Results We found ERBB2, ALK, MLL4, PIK3CB, and TOP2A were mutated at a significantly lower frequency in oligometastasis compared with polymetastasis. EGFR and KEAP1 alterations were mutually exclusive in oligometastatic group. More importantly, oligometastasis has a unique significant enrichment of apoptosis signaling pathway. In contrast to polymetastasis, a highly enriched COSMIC signature 4 and a special mutational process, COSMIC signature 14, were observed in the oligometastatic cohort. According to OncoKB database, 74.03% of oligometastatic NSCLC patients harbored at least one actionable alteration. The median tumor mutation burden of oligometastasis was 5.00 mutations/Mb, which was significantly associated with smoking, DNA damage repair genes, TP53 mutation, SMARCA4 mutation, LRP1B mutation, ABL1 mutation. Conclusion Our results shall help redefine oligometastasis beyond simple lesion enumeration that will ultimately improve the selection of patients with real oligometastatic state and optimize personalized cancer therapy for oligometastatic NSCLC.