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Current status of functional dyspepsia in Korea
이혁,정혜경,허규찬,Functional Dyspepsia Study Group in the Korean 대한내과학회 2014 The Korean Journal of Internal Medicine Vol.29 No.2
Dyspepsia refers to group of commonly occurring upper gastrointestinal symptoms. The majority of patients with dyspepsia suffer from functional (nonulcer)dyspepsia. Although there is a lack of epidemiological data from population-basedor patient cohort studies in Korea, the current understanding of this conditionhas been updated using data from various recent research studies, which have facilitatedthe development of clinical guidelines for functional dyspepsia. Accordingto a survey using the Rome III criteria, more than 40% of respondents whovisited primary clinics and tertiary hospitals were defined as having functionaldyspepsia, most of who were within a subgroup of patients with postprandial distresssyndrome. In addition, a population-based cross-sectional survey revealedconsiderable overlap between functional dyspepsia and other functional gastrointestinaldisorders, including gastroesophageal reflux disease (especially nonerosivereflux disease) and irritable bowel syndrome. In contrast to the results ofWestern trials, there is insufficient evidence to recommend a Helicobacter pyloritest-and-treat strategy as an initial management approach to functional dyspepsiain Korea, suggesting the need for early endoscopic evaluation. Additionalstudies are necessary to adjust the cutoff age for implementation of immediateendoscopic evaluation of patients without alarm symptoms. Considering theprevalence of H. pylori infection and the limited efficacy of symptomatic relief afterits eradication, further well-qualified studies in Korea are warranted.