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김동식 ( Kim¸ Dongsik ) 한국보건사회연구원 2021 국제사회보장리뷰 Vol.18 No.-
아일랜드는 2019년까지만 하더라도 임부와 태아의 생명권을 동등하게 부여한 수정헌법 제8조로 인해 임신중지 의료서비스를 영국 등 인근 국가로 이동하여 제공받을 수밖에 없었지만, 2018년 5월 국민투표로 기존 법을 폐지하고 임신 12주까지는 여성의 요청으로 임신중지가 합법화된 새로운 시대를 맞이하였다. 그러나 신설 조항에는 여성의 자기결정권과 안전한 임신중지를 위한 의료서비스 접근에 논쟁이 되는 쟁점이 있었다. 최근 법에 근거하여 시행된 의료정책에 대한 문제점과 한계를 지적하는 평가 결과가 발표되어 이를 검토함으로써 지난 2019년 헌법재판소의 낙태죄 헌법불합치 결정 이후 대체입법이 마련되지 않는 우리에게 주는 시사점을 얻고자 하였다.
박지호,김동식 순천향대학교 부설 산업기술연구소 2021 순천향 산업기술연구소논문집 Vol.27 No.2
Goldman Sachs recently laid off 598 top talents, while Google and NASA established a singularity university. As we enter the era of the 4th Industrial Revolution, each company and university is nurturing talent for the age of artificial intelligence(AI). As factories and various facilities are automated and AI and the Internet of Things (IoT) enter homes and businesses, interest in automation is gradually increasing, and AI robots are replacing human jobs. Therefore, a study was conducted on the implementation of a sorting robot for smart factory automation. The hardware of the robot was realized using TETRIX, and it was configured to recognize the color of blocks and classify the object using NXT color sensors. The color sensor is used to determine the type of a block and a linetracer is to help figure out location, and the block was placed in the right place. The control program was implemented using LabVIEW, and the NXT was implemented to control the robot through the signal obtained from the color sensor.
Yongsik Kim,Minkyung Bae,Woojoon Kim,Dongsik Kong,Hyun Kwang Jung,Hyungtak Kim,Sunwoong Kim,Dong Myong Kim,Dae Hwan Kim IEEE 2012 IEEE transactions on electron devices Vol.59 No.10
<P>A combination of the multifrequency <I>C</I>- <I>V</I> and the generation-recombination current spectroscopy is proposed for a complete extraction of density of states (DOS) in amorphous InGaZnO thin-film transistors (a-IGZO TFTs) over the full subband-gap energy range (<I>EV</I> ≤ <I>E</I> ≤ <I>EC</I>) including the interface trap density between the gate oxide and the a-IGZO active layer. In particular, our result on the separate extraction of acceptor- and donor-like DOS is noticeable for a systematic design of amorphous oxide semiconductor TFTs because the former determines their dc characteristics and the latter does their threshold voltage (<I>VT</I>) instability under practical operation conditions. The proposed approach can be used to optimize the fabrication process of thin-film materials with high mobility and stability for mass-production-level amorphous oxide semiconductor TFTs.</P>
Dongsik Kong,Hyun-Kwang Jung,Yongsik Kim,Minkyung Bae,Yong Woo Jeon,Sungchul Kim,Dong Myong Kim,Dae Hwan Kim IEEE 2011 IEEE electron device letters Vol.32 No.10
<P>The effect of the active layer thickness (<I>T</I><SUB>IGZO</SUB>) on the negative bias stress (NBS)-induced threshold voltage shift (Δ<I>VT</I>) in amorphous InGaZnO (a-IGZO) thin-film transistors (TFTs) is investigated and explained by using a subgap density-of-states (DOS) model. The NBS-induced negative Δ<I>VT</I> in a-IGZO TFT with a thinner <I>T</I><SUB>IGZO</SUB> is larger than that with a thicker <I>T</I><SUB>IGZO</SUB>. Based on the simulation result with the subgap DOS model, it is concluded that the <I>T</I><SUB>IGZO</SUB>-dependent Δ<I>VT</I> is originated from the accelerated creation of shallow donor states due to a higher surface electric field in a-IGZO TFTs with a thinner <I>T</I><SUB>IGZO</SUB>.</P>
Centennial History of Yonsei University Dermatology in Korea: 1917 to 2017
( Jihee Kim ),( Tae-gyun Kim ),( Si Hyung Lee ),( Min Kyung Lee ),( Jong Hoon Kim ),( Sang Eun Lee ),( Do Young Kim ),( Mi Ryung Roh ),( Chang Ook Park ),( Ju Hee Lee ),( Min-geol Lee ),( Dongsik Bang 대한피부과학회 2018 Annals of Dermatology Vol.30 No.5
Yonsei Dermatology celebrated its centennial in 2017, marking 100 years since Kung Sun Oh established the first Department of Dermatology and Urology in Korea in 1917. Following the footsteps of Kung Sun Oh, a pioneer of Korean dermatology, its members united and worked to provide the best medical service and achieve academic milestones in dermatology. Over the past hundred years, Yonsei Dermatology has played a pivotal role in the advancement of medical science and academia in Korea. The main activities of the department include medical care, education, and dermatologic research. Its research activities have encompassed a wide spectrum of dermatologic manifestations from skin immunology and pathology to introduction of newly developed treatment technologies. As Kung Sun Oh was the first Korean professor of dermatology at Severance Medical School and a passionate educator, we continue to serve his will by nurturing medical students and dermatology special-ists to serve as global medical leaders. The Kung Sun Oh Memorial Lecture, first hosted in 1977, was the beginning of mutual international academic exchange in the field of dermatology in Korea. The memorial lecture has played a major role in advancing the academic status of Korean dermatological science by inviting distinguished dermatologists from around the world as guest lecturers. Yonsei Dermatology has played a key role in the history of modern medicine and dermatology in Korea over the last 100 years and continues to make an impact. (Ann Dermatol 30(5) 513∼521, 2018)
Effective PEI-mediated delivery of CRISPR-Cas9 complex for targeted gene therapy
Ryu, Nari,Kim, Min-A,Park, Dongsik,Lee, Byeonghyeon,Kim, Ye-Ri,Kim, Kyung-Hee,Baek, Jeong-In,Kim, Won Jong,Lee, Kyu-Yup,Kim, Un-Kyung Elsevier 2018 Nanomedicine: Nanotechnology, Biology and Medicine Vol.14 No.7
<P><B>Abstract</B></P> <P>The-state-of-art CRISPR/Cas9 is one of the most powerful among the approaches being developed to rescue fundamental causes of gene-based inheritable diseases. Several strategies for delivering such genome editing materials have been developed, but the safety, efficacy over time, cost of production, and gene size limitations are still under debate and must be addressed to further improve applications. In this study, we evaluated branched forms of the polyethylenimine (PEI) – branched PEI 25 kDa (BPEI-25K) – and found that it could efficiently deliver CRISPR/Cas9 plasmids. Plasmid DNA expressing both guide RNA and Cas9 to target the <I>Slc26a4</I> locus was successfully delivered into Neuro2a cells and meditated genome editing within the targeted locus. Our results demonstrated that BPEI-25K is a promising non-viral vector to deliver the CRISPR/Cas9 system <I>in vitro</I> to mediate targeted gene therapy, and these findings contribute to an understanding of CRISPR/Cas9 delivery that may enable development of successful <I>in vivo</I> techniques.</P> <P><B>Graphical Abstract</B></P> <P>Schematic of gene delivery by cationic polymer polyethylenimine (PEI) – branched PEI 25 kDa (BPEI-25K). The plasmid expressing both CRISPR/Cas9 and guide RNA forms compact complexes with BPEI-25K and is protected from degradation by lysosomal enzymes. The plasmid DNA is released into the cytosol and enters into the nucleus. The plasmid is translated into Cas9:sgRNA complex and nuclear localized for gene editing.</P> <P>[DISPLAY OMISSION]</P>