부산시 일개구 지역주민의 위암선별검사 수검 및 반복수검 실태 및 관련요인조사

정인숙,배은숙,천동환,전진호,이화자,박남희 韓國保健敎育.健康增進學會 2003 보건교육건강증진학회지 Vol.20 No.1

The importance of repeat screening for stomach cancer is well known to decrease deaths from stomach cancer. This study was aimed at assessing practice behaviors and to identify related factors in the aspects of demographic factors, health status and cancer risk recognition, attitude to cancer screening, health behaviors, and inhibiting or facilitating factors to stomach cancer screening in an urban area. Data was collected through self-administered questionnaires from 403 people aged 40 to 69 years from April 23th to May 15th, 2002. Practice behaviors were classified as :"ver"r "ver"and "peat"r "t repeat"rouped based on a recent 5 year screening history. The results were as follows: 1. Among the 403 subjects: "e ever group"as 23.8% and "e repeat group"as 4.0%. The rates of screening were 20.5% for men, 27.8% for those women, and 27.3% for aged 40-49, 24.5% for those aged 50-59, 19.0% for those aged 60-69. The rates of repeat screening were 4.0% for men, 4.1% for women, and 2.9% for those aged 40-49, 6.3% for aged 50-59, 2.5% for those aged 60-69. 2. The main factors associated with adherence to gastric cancer screening were education(post high school vs below : OR=2.44), previous cancer screening(yes vs no : OR=2.61), belief in personal health(no vs yes : OR=2.72), health status(unhealthy vs healthy : OR=3.40), possibility of cancer compared to others(low vs not low : OR=2.56), and regular exercise(yes vs no : OR=2.94). The main factor associated with adherence to gastric cancer repeat screening was other cancer screening (yes vs no : OR=6.33). Consequently, there is a need to change the recognition of the importance and necessity of stomach cancer screening in healthy conditions through health education, and to perform multiple screening tests each visit.

Robust Control Design Applicable to General Flexible Joint Manipulators

Dong Hwan Kim(김동환),Ye-Hwa Chen(에화첸) 제어로봇시스템학회 1998 제어·로봇·시스템학회 논문지 Vol.4 No.1

Generation of Insulin Producing Cells from the Mouse Primary Hepatocytes

( Dong Sik Ham ),( Ji Won Kim ),( Heon Seok Park ),( Chen Lin Sun ),( Seung Hwan Lee ),( Jae Hyoung Cho ),( Jeong Ah Oh ),( Ki Ho Song ),( Ho Young Son ),( Kaneto Hideaki ),( Kun Ho Yoon ) 한국조직공학·재생의학회 2011 조직공학과 재생의학 Vol.8 No.6

Surrogate β-cells derived from available adult stem cells are urgently needed for the treatment of insulindeficient diabetes, and hepatocytes constitute an attractive alternative. Herein, we attempted to generate insulin-producing cells from adult mouse primary hepatocytes (HCs) using triple adenoviruses harboring PDX-1/VP-16, BETA2, and MafA. We noted characteristic changes in the transduced HCs into pancreatic β-cells, including reduced albumin gene and increased insulin, insulin content, and the expression of a variety of pancreatic genes. Glucose tolerance and survival are improved by the renal capsular transplantation. These data demonstrated that the transdifferentiation of HCs into insulin-producing cells could be achieved under both in vitro and in vivo conditions. Further, these data suggest that induction of insulin-producing cells from liver provides a potential cell-replacement therapy for the treatment of patients with diabetes using alternative transplantable cell source.

Quinoline-Based Two-Photon Fluorescent Probe for Nitric Oxide in Live Cells and Tissues

Dong, Xiaohu,Heo, Cheol Ho,Chen, Shiyu,Kim, Hwan Myung,Liu, Zhihong American Chemical Society 2014 ANALYTICAL CHEMISTRY - Vol.86 No.1

<P>A two-photon fluorescent probe (QNO) for nitric oxide is reported. The probe is designed with a photoinduced electron transfer (PeT) mechanism and shows 12-fold fluorescence enhancement toward NO. Adopting a quinoline derivative as the fluorophore, QNO has a large two-photon action cross section value of 52 GM and long-wavelength emission. It also features high selectivity, low cytotoxicity, and pH insensitivity. By utilizing two-photon microscopy (TPM), QNO can detect NO in live cells and live tissues at a depth of 90-180 mu m.</P>

Effects of Different Salt Treatments on the Fermentation Metabolites and Bacterial Profiles of Kimchi : Salt effect on kimchi fermentation…

Kim, Dong Wook,Kim, Bo-Min,Lee, Hyeon-Jeong,Jang, Gwang-Ju,Song, Seong Hwa,Lee, Jae-In,Lee, Sang Bong,Shim, Jae Min,Lee, Kang Wook,Kim, Jeong Hwan,Ham, Kyung-Sik,Chen, Feng,Kim, Hyun-Jin Wiley Blackwell (Blackwell Publishing) 2017 Journal of food science Vol.82 No.5

Region-Based Object Recognition by Color Segmentation Using a Simplified PCNN

Yuli Chen,Yide Ma,Dong Hwan Kim,Sung-Kee Park IEEE 2015 IEEE transactions on neural networks and learning Vol.26 No.8

<P>In this paper, we propose a region-based object recognition (RBOR) method to identify objects from complex real-world scenes. First, the proposed method performs color image segmentation by a simplified pulse-coupled neural network (SPCNN) for the object model image and test image, and then conducts a region-based matching between them. Hence, we name it as RBOR with SPCNN (SPCNN-RBOR). Hereinto, the values of SPCNN parameters are automatically set by our previously proposed method in terms of each object model. In order to reduce various light intensity effects and take advantage of SPCNN high resolution on low intensities for achieving optimized color segmentation, a transformation integrating normalized Red Green Blue (RGB) with opponent color spaces is introduced. A novel image segmentation strategy is suggested to group the pixels firing synchronously throughout all the transformed channels of an image. Based on the segmentation results, a series of adaptive thresholds, which is adjustable according to the specific object model is employed to remove outlier region blobs, form potential clusters, and refine the clusters in test images. The proposed SPCNN-RBOR method overcomes the drawback of feature-based methods that inevitably includes background information into local invariant feature descriptors when keypoints locate near object boundaries. A large number of experiments have proved that the proposed SPCNN-RBOR method is robust for diverse complex variations, even under partial occlusion and highly cluttered environments. In addition, the SPCNN-RBOR method works well in not only identifying textured objects, but also in less-textured ones, which significantly outperforms the current feature-based methods.</P>

단보 : 국민참여형 위성영상 블로그 시스템 구축

이기환 ( Ki Hwan Lee ),이동천 ( Dong Chen Lee ),박석호 ( Seok Ho Park ),김일 ( Il Kim ),신상희 ( Sang Hee Shin ) 大韓遠隔探査學會 2007 大韓遠隔探査學會誌 Vol.23 No.2

전라남도 국민참여형 위성영상 블로그 시스템은 2006년도 행정자치부 자치단체정보화지원사업의 일환으로 구축된 것으로서 시용자가 고해상도 위성영상 위에 직접 자신의 글 사진, 동영상을 올리고, 이를 다른 사용자나 시스템과 공유할 수 있도록 구축된 시스템이다. 본 시스템이 궁극적으로 구현하고자 했던 과제는 다음과 같다. ①지리정보 혹은 기타 정보의 고정성을 탈피하고, ②지리정보와 멀티미디어 자료의 효율적 통합을 통해 geoUCC를 구축하며, ③사용자의 참여를 통한 지리정보 제공 방식의 쌍방향성을 구현하여, ④ 사용자를 일방적 자료 활용자에서 자료 생성자로 발전시키고 궁극적으로는 자치단체와 국민 간 새로운 방식의 소통 방식을 생성하는 것이다. 본 시스템 구축의 결과로서 본 시스템에서 일반 국민에게 서비스 되는 내용은 다음과 같다. ① 전라남도 전역의 1m급 고해상도 위성영상의 대국민 서비스, ②전라남도 전역에 대한 지번 단위까지의 주소 검색 서비스, ③웹 상에서의 실시간 3차원 GIS 서비스, ④Web2.0의 철학을 반영한 RSS, Trackback 기능 및 Tag 검색 기능, ⑤시용자가 직접 고해상도 위성영상 위에 자신의 글, 사진, 동영상, 홈페이지 등을 올릴 수 있는 "위성영상 블로그 쓰기 기능", ⑥국내 거의 모든 포털 사이트의 블로그와 홈페이지를 지원하는 시스템 연계(퍼가기) 기능 등이다. 결론적으로 본 시스템의 사용자는 고해상도 위성영상 기반의 지도 위에 자신의 여행기, 사진, 동영상을 올림으로써 자신만의 사용자제작콘텐츠(UCC)를 생성할 수 있을 뿐만 아니라, 이를 다른 사용자와 공유, 활용함으로써 실질적인 쌍방향, 참여형 지리정보시스템을 이용하게 된 것이다. This paper introduce a satellite image based blog system built by JeonNam local province. Main goals of this system are as follows: ①Overcome the static aspect of traditional Web-GIS, ②Providing a geoUCC generating platform by combining multimedia technology and GIS in a single web environment, ③Building a two-way Web-GIS through user`s participation, ④Creating a new communicative way between government and citizen by using this system. As a result of the system building, this system enables users to create his/her own UCC(User Created Contents) on high-resolution satellite image and enables users to share his/her own UCC with other system using Web2.0 technology.

A Science Gateway Cloud With Cost-Adaptive VM Management for Computational Science and Applications

Kim, Seong-Hwan,Kang, Dong-Ki,Kim, Woo-Joong,Chen, Min,Youn, Chan-Hyun IEEE 2017 IEEE systems journal Vol.11 No.1

<P>For the processing of scientific applications in cloud computing, the important challenge is to find an optimized resource scheduling method that guarantees cloud service users' service-level agreement while minimizing the resource management cost. To overcome this problem, in contrast to previous solutions that focus on a few specific applications, we design and implement a unified scientific cloud framework called science gateway cloud, which is a broker between users and providers and is able to process various scientific applications efficiently upon heterogeneous cloud resources. In particular, we design a costadaptive resource management scheme that reduces the resource management cost significantly without any degradation of performance based on the long-term payment plans of cloud resource providers. Furthermore, this system allows us to parallelize divisible scientific applications to improve the processing performance. Through the division policy for workflow scheduling, we show that both deadline assurance and cost minimization can be satisfied concurrently. Finally, we demonstrate that our proposed system significantly outperforms conventional cloud systems through various experimental and simulation results.</P>

Functional characterization of <i>ObgC</i> in ribosome biogenesis during chloroplast development

Bang, Woo Young,Chen, Ji,Jeong, In Sil,Kim, Sam Woong,Kim, Chul Wook,Jung, Hyun Suk,Lee, Kyoung Hwan,Kweon, Hee‐,Seok,Yoko, Ishizaki,Shiina, Takashi,Bahk, Jeong Dong Blackwell Publishing Ltd 2012 The Plant journal Vol.71 No.1

<P><B>Summary</B></P><P>The Spo0B‐associated GTP‐binding protein (Obg) GTPase, essential for bacterial viability, is also conserved in eukaryotes, but its primary role in eukaryotes remains unknown. Here, our functional characterization of Arabidopsis and rice <I>obgc</I> mutants strongly underlines the evolutionarily conserved role of eukaryotic Obgs in organellar ribosome biogenesis. The mutants exhibited a chlorotic phenotype, caused by retarded chloroplast development. A plastid DNA macroarray revealed a plastid‐encoded RNA polymerase (PEP) deficiency in an <I>obgc</I> mutant, caused by incompleteness of the PEP complex, as its western blot exhibited reduced levels of RpoA protein, a component of PEP. Plastid rRNA profiling indicated that plastid rRNA processing is defective in <I>obgc</I> mutants, probably resulting in impaired ribosome biogenesis and, in turn, in reduced levels of RpoA protein. RNA co‐immunoprecipitation revealed that ObgC specifically co‐precipitates with 23S rRNA <I>in vivo</I>. These findings indicate that ObgC functions primarily in plastid ribosome biogenesis during chloroplast development. Furthermore, complementation analysis can provide new insights into the functional modes of three ObgC domains, including the Obg fold, G domain and OCT.</P>

Robust control design applicable to general flexible joint manipulators

김동환,챈 예화,Kim, Dong-Hwan,Chen, Ye-Hwa 제어·로봇·시스템학회 1998 제어·로봇·시스템학회 논문지 Vol.4 No.1

불확실한 변수와 비선형성을 가지는 유연조인트 로봇의 견실제어 방안을 제시한다. 그리고 본 시스템에서 불확실구조는 일치성을 유지하지 않는 불일치성 불확실 시스템이다. 제어기는 리아노프의 방안에 근거를 두고있다. 견실제어는 연산토크법을 사용하고 삽입제어기법을 통하여 좌표변환을 통해 구성된다. 제어기 설계과정은 우선 연산토크방법에 의해 시스템 동역학에서 정격부분을 선형으로 2개의 부분시스템으로 구성한다. 이후 좌표변환을 이용하여 각 부분시스템에 제어기를 구축한다. 이 방안을 통하여 관성 행렬이 알려진 값인 경우 이 행렬의 상위한계 조건없이 제어기를 설계할 수 있다. 따라서 임의의 형태의 로봇에도 적용 가능한 제어알고리즘이 된다. 설계된 견실제어는 변환된 시스템이나 원시스템 모두 실용적 안정성을 보장한다. 이 변환은 단지 불확실변수의 최대 한계값의 정보만을 요구한다.