방사선조사가 백서의 치주조직에 미치는 영향에 관한 실험적 연구

박대희,이상래 大韓口腔顎顔面 放射線學會 1986 Imaging Science in Dentistry Vol.16 No.1

It is known that radiation therapy is a kind of treatment choices of the maxillofacial tumors. This study is designed to investigate the irradiation effects on rat's periodontal tissues as functional tissues which relate to tooth-support, hard tissue formation and destruction. 20 rats (Sprague-Dowley branch, male) were devided into control group of 4 and experimental groupe of 16. Experimental group was singly exposed to Co-60 irradiation with 10 Gy in the head and neck region. Animals were sacrificed on 2 bays, 1 week, 2 weeks and 3 weeks after the irradiation. The specimens were observed by histopathological examination employing H-E stain, van-Gieson stain and PA-ACH fluorescent stain. The results were as follows: 1. Cementoblasts and osteoblasts were gradually lost and rearranged along the external surfaces of the cementum and alveolar bone, but osteoclasts were almost not affected. 2. The cell numbers of the periodontal ligament were decreased due to the cellular atrophy and degeneration, but recovered almost normally on the 3rd week after irradiation. 3. The collagen fibers within the periodontal ligament were irregularly oriented, became finer and decreased in number. 4. The vessels of the periodontal ligament were decreased at the initial stage but increased again on the 2nd week after irradiation, and the hemorrhagic appearances, occurred within the tissues, due to the arterial destruction, were lasted until 3 weeks after irradiation. 5. The glycogen within the periodontal ligament was gradually and stored in the matrices of the cemental side on the 1st week after irradiation, but recovered almost normally on the 3rd week after irradiation.

박테리아의 生育에서 Aspergillas flavus 抽出物과 SH group의 相關作用

李大熙,崔鎬亨 공주대학교 사범대학 과학교육연구소 1987 과학교육연구 Vol.19 No.1

Aspergillus flavus 抽出物과 Aflatoxin 및 ρCMB가 박테리아의 생장과 증식과정에 미치는 형태와 억제의 정도 및 작용의 유사성을 조사하기 위하여 이들 각각의 저해 물질들을 배양액에 처리하여 박테리아를 배양 실험하였다. 또한 SH group이 이들 저해물질들의 저해작용을 완화할 수 있는지의 여부를 조사하기 위하여 각 저해물질과 glutathione을 同量으로 처리하여 박테리아의 증식변화를 추적하였다. 얻어진 결과는 다음과 같았다. 1. Aspergillus flavus 抽出物 1mg(dry weight) 은 박테리아 증식을 50% 억제하였다. 2. Aflatoxin B₁을 농도별로 배양액에 처리한 결과 박테리아 증식은 10??M 에서 45% 10??M에서 21%정도 억제되었다. 3. ρCMB 10??M에서 박테리아 생장과 증식은 45% 억제되었다. 4. Aflatoxin B₁과 ρCMB는 박테리아의 생육억제의 크기나 형태변화 유발등에서 유사하였다. 그러나 생육장해를 주는 방법에 있어서는 서로 차이가 있었다. 5. ρCMB의 장해는 glutathione에 의하여 보완적이었으나 Aflatoxin B₁에 의한 장해는 거의 보완되지 않았다. 6. Aspergillus flavus 抽出物에 의하여 박테리아의 증식이 억제되었을 경우 glutathione처리를 하였을 때 14%정도 보완되었다. 7. Aspergillus flavus 抽出物중에서 박테리아 生育을 억제하는 성분은 Aflatoxin만이라고 한정할 수 없었으며 또한 그 저해작용은 SH아미노산에 의하여 상당히 보완될 수 있었다. In order to examine mode and rate of inhibition and the similarity of biochemical process that Aspergillus flavus extract aflatoxin and ρCMB effect on the process of its growth and reproduction of bacteria, it was experimented as treating each inhibitor into bacterial culture medium. In order to examine whether SH group could be on the decrease in the rate of inhibition, the reproductive mode in bacteria was investigated by means of treating as the same amount of each inhibitor and glutathione. Reproduction and groth of bacteria was decreased about 50% by Aspergillus flavus extract lmg(dry weight) Reproduction of bacteria was inhibited about 45% in 10??M and 21% in 10??M. The reproduction of the bacteria was decreased 45% in 10??M ρCMB-treated medium. Aflatox B₁and ρCMB showed the similar tendency of the inhibition rate in reproduction and causing the alternation of morphologic modification of bacteria. However, there were dissimiliar to the phenomenon of inhibition. The inhibition of ρCMB was offset by glutathione in the large percentage but the inhibition by aflatoxin was not almost offset by aflatoxin. Inhibition by Aspergillus flavus extract was offseted about 14% by treatment of 10??M glutathione. Inhibitory components of Aspergillus flavus extract could not define only aflatoxin and inhibition could be same offset by glutathione.

흥미로운 구조를 가진 Dipyrrolylbenzene들의 합성에 관한 연구

정대일,김인식,정두희,박철우,김윤영 東亞大學校 大學院 1996 大學院論文集 Vol.21 No.-

1-(2-Aminophenyl)pyrrole 20a and 1,2-dipyrrolylbenzene 17a were synthesized by using 1,2-phenylenediamine 16a with 2,5-dimethoxytetrahydrofuran 12 in glacial acid. 1-(3-Aminophenyl)pyrrole 20b and 1,3-dipyrrolylbenzene 17b were obtained by using 1,3-phenylenediamine 16b with 2,5-dimethoxytetrahydrofuran 12 in glacial acetic acid. 1,4-Dipyrrolybenzene 17c was synthesized by using 1,4-phenylenediamine 16c with 2,5-dimethoxytetrahydrofuran 12 in glacial acetic acid. Aminophenylpyrroles 20 and dipyrrolylbenzenes 17 were respectively synthesized by the treatment of 1,2-phenylenediamine 16a, 13-phenylenediamine 16b, 1,4-phenylenediamine 16c and 2,5-dimethoxytetrahydrofuran 12 in no solvent, acrylic acid, silica-gel, acrylic acid + silica-gel + acetic acid instead of glacial acetic acid. In case of silica-gel + acetic acid among various methods reactivity about synthesis of dipyrrolylbenzene 17 was best. 9-Phenylcarbazole 15 was synthesized by treatment of 1-phenylpyrrole 13 with 2,5-dimethoxytetrahydrofuran 12 in glacial acetic acid.

Acylthiocholine의 합성

정두희,이지현,박유미,정대일,곽문정,신영주 東亞大學校附設基礎科學硏究所 1998 基礎科學硏究論文集 Vol.15 No.2

Choline esters that are used with substrate of EE-AChE-catalyzed hydrolyses were synthesized by two methods. 2-Chloroethyl thiohexanoate 4a, 2-chloroethyl thioheptanoate 4c, and 2-chloroethyl thiooctanoate 4b were synthesized by treatment of hexanoyl chloride 3a, heptanoyl chloride 3c, and octanoyl chloride 3b with ethylene sulfide 2. Hexanoylthiocholine 6a and octanoylthiocholine 6b were synthesized by using 4a and 4b with trimethylamine 5. Secondly after reaction ethylene sulfide 2 with dimethyl amine 7 and acylation by acid anhydride 8, heptanoylthiocholine 6c, decanoylthiocholine 6d were synthesized by treatment of methyl iodide.

1,2-Benzisothiazol-3-one-1,1-Dioxide 유도체의 합성

정대일,정희철,변석인,이용균,박유미,최순규,한정태 東亞大學校附設基礎科學硏究所 2002 基礎科學硏究論文集 Vol.19 No.1

사카린 유도체는 제초제, 항독성, 살균제 등에 광범위하게 연구되어져 오고 있다. 새로운 농략 활성을 가진 물질을 합성하기 위해 먼저 선도물질로 사카린 1을 산화, 염소화 시킨 3-chloro-1,2-benzisothiazol-1,1-dioxide(BID-CI) 2와2cholromethy-1,2-benzisohizol-3-one1,1-dioxide 4를 합성하였다. 선도물질, amines, imidazoles, trones등과 반응시켜 다음과 같은 물질들을 얻었다. ; 3-cyclohexylamino-1,2-benzisothiazol-1,1-dioxide 6, 3-furylamino-1,2-benzisothiazol-1,1-dioxide 8, 3-(3-imidazol)-1,2-benzisothiazol-1,1-dioxide 10, 3-(2-methy-3-imidazol)-1,2-benzisothaizol-1,1-dioxide 12, 2-(3-imidazol)methy-1-1,2-benzisothiazol-3-one-1,1-dioxide 13, and 2-(-3-imidazol)methyl- 1,2-benzisothiazol-1,1-dioxide 14.

용매침윤 수지에 의한 중금속 회수에 관한 연구

李大云,李垣,金珠姬,李承頀 연세대학교 대학원 1981 延世論叢 Vol.18 No.1

The application of the solvent-impregnated resin(SIR), 5,7-dibromo-8-hydroxyquinoline(DBQ)-impregnated polyurethane foam, to the selective recovery of some heavy metal ions from aqueous solution was investigated. The adsorption behavior of DBQ on polyurethane foam was studied to determine the optimum conditions for preparing the SIR. It was found that SIR impregnated with DBQ had adsorption capacity about 5×10-2 mmol M(II) per gram foam. The conditions for recovery and readsorption of metal ions were determined.

TiO₂를 이용한 프로필렌 가스의 광촉매 산화반응

정대일,이동희,김용환,김현숙,이용균,박유미,최순규,김동현 동아대학교 환경문제연구소 2001 硏究報告 Vol.24 No.1

Photocatalyzed degradation of propylene gas was carried out over precoated titanium dioxide(anatase) illuminated W light in a flow reactor. photocatalytic oxidation of propylene gas indicated high conversion rates (78.0%) to CO₂ gas. And photocatalytic oxidation of gas according to a fold, twofold, and threefold of titanium dioxide(anatase) respectively gave high conversion rate. The longer reaction time was, the higher conversion rate to CO₂ gas showed.

사상규칙과 소함수를 이용한 간호정보시스템의 스키마 사상 모듈의 설계 및 구현

김대희,전종훈 명지대학교 산업기술연구소 2001 産業技術硏究所論文集 Vol.20 No.-

Data interchange module for data sharing in a distributed database system envirionment is indispensible. Especially, inconsistency problem incurred by heterogeneous schema and database management system are known to be the most difficult one. This paper proposes a schema mapping method for data interchange between nursing information system and hospital information system. The method is based on the use of rule map and mini functions and the former is for providing schema mapping information and the latter is tailored for each individual database management system. The rule map and mini function resolves mismatch problem, which in turn makes it possible to implement effective data interchange module.

조리방법에 따른 식품 중 영양소 잔존률(retention factor)에 관한 연구(Ⅰ) : 채소류 및 감자류 Vegetablesn ane potatoes

김대병,장영미,김인복,이혜영,장재희,박정현,엄세정 식품의약품안전청 2000 식품의약품안전청 연보 Vol.4 No.-

조리조건에 따른 식품의 영양소 잔존를을 측정하여 보다 정확한 조리식풍에 의한 영양소 섭취량을 평가할 수 있도록 하기 위하여 합리적인 영양소섭취량 조사, 영양 평가를 위한 개선책을 제시하고자 끓였다. 대상 시료와 조리법은 시금치(데치기, 끓이기), 배추(끓이기), 콩나물(데치기, 끓이기), 호박(끓이기, 볶기). 당근(끓이기, 볶기), 우엉(조림), 감자(끓이기, 볶기)이었으며, 조리 전 후의 비타민 A(β -carotene), Bl, B2, C, E, 나이아신, 칼슘, 철, 아연, 칼륨, 인, 나트륨의 함량을 분석하여 조리법에 따른 잔즌률을 국하였다. 조리조건별 잔존률을 구한 결과 무기질은 데치기의 경우 조리수를 제거하므로 손실이 있었으나 끓이기, 볶기 등의 조리법에서는 손실이 거의 없었다. 비타민 A와 I는 대부분 80%이상으로 많이 손실되지 않았으며 비타민 Bi은 데치기가 가장 낮았고, 조림, 괄이기, 볶기의 순으로 잔존률이 높았다. 비타민 B2와 나이아신은 비타민 Bi보다는 잔존를이 높은 경향이었다. 비타민 C는 대부 분의 조리법에서 크페 손실되었다. 본 연구의 결과는 합리적이고 정확한 영양소 섭취량 평가를 위한 기초자료로서 기존의 평가방법을 개선 보완하여 영양소섭취량 평가으 과학화에 기여할 것으로 기대된다. In various mutrition activities, the necessary values of nutrient intake were usually calculated from food composition tables which have nutrient contents of raw ingredients and dishes, but Korean food composition tables of dishes were lacking, So we studied todetermine the nutnent retention factors(RF) of vegetables and potatoes by cooking methods. Atfirst, we surveyed cooking methods of vegetables and potatoes, and selected major vegetablesand cooking methods. Selected items and cooking methods were sp.mach(blanching and boiling),cRnese cabbage(boiling), soybean sprout(bBanchlng and boiling), pumpkin(boiling andstir-frying), carlot(boiling and stir-frying), burdock(braising), and potato(boiling and stir-frying)We analyzed 6 vitamins luhich were vitamin A(β-carotene), Bl, B2, C, E, and niacin, and 6minerals which were calciurrl, iron, zinc, potassium, phosphorus, and sodium. The results wereas follows : Minerals almost retained in boiling, stir-frying, except in blanching method, RF ofvitamin A and I were 80% or more. RF of vitandn Bl were decreased in order of sfir-frying,boiling, braising, blanching and the RF of vitamin B2 and niacin were higher than vitandn Bl,RF of the vitamin C were varird in So~90% in all cooking methods

축사용 지붕재료의 복사열전달에 관한 연구

장희대 충북대학 대학원 1977 大學院論文集 Vol.3 No.-

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