남성화를 보이는 여성에서 발견된 난소의 Steroid Cell Tumor 1예

조인호,정대훈,박영미,서영진,손영실,정철회,강영미,정수전,김영남,이경복,성문수,김기태 인제대학교 2006 仁濟醫學 Vol.27 No.-

Steroid cell tumor is a rare ovarian sex cord-stromal tumor which accounts for 0.1% of all ovarian tumors. Until now, only 4 cases have been reported in domestic literatures. Steroid cell tumor often secrets testosterone and presents virilization in adult women or precocious puberty in children. Treatment is often performed by surgical removal, adjuvant chemotherapy and radiation, but completely accepted treatment was not existed. We experienced a case of steroid cell tumor, which was manifested by typical virilization in a 43-year old patient, who was previously performed hysterectomy and unilateral oophorectomy. So, we present with a brief review of the literatures.

Retinol 국소도포에 의한 눈가주름 제거효과

전희대,이성열,이혜진,박영립,이종석,황규왕 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.2

In 3 months randomized, double-blind, vehicle-controlled study of retinol (vitamin A 0.1%-3000IU/g) in the treatment of photoaging skin, especially eye wrinkles. 24 patients applied retinol contained cream to the both eye wrinkles and vehicle cream(placebo) to the same site. Half of the patients received retinol contained cream and half received vehicle cream(placebo). All 24 patients who completed the study showed statistically significant improvement in photoaging eye wrinkles on the retinol contained cream treated group, but not on the vehicle treated group. Eight of the 12 patients who received retinol contained cream to eye wrinkles had improvement in photoaging, whereas only three of the 12 patients who received vehicle cream(placebo) improved. In retinol contained cream group, there is a some relationship between water contents and effects. In other words, as water contents were the higher, effects were the better. The side effects were limited to mild irritation of retinol contained cream treated skin. Retinol contained cream appeared to be safe and effective in the treatment of eye wrinkles.

자궁내막에 발생한 점막 연관 림프조직 (MALT) 림프종 1예

전균호,조현진,박성균,김천복,김대연,김종혁,김용만,김영탁,목정은,남주현 대한부인종양 콜포스코피학회 2003 Journal of Gynecologic Oncology Vol.14 No.4

Non-Hodgkin's 림프종의 약 40%는 결절외(extranodal) 림프종으로 대개 위장관에서 발생하며 이들 중 점막 연관 림프조직(mucosa-associated lymphoid tissue: MALT)에서 기원한 림프종은 MALT 림프종으로 분류된다. 위 외의 부위에서 원발성으로 발생하는 MALT 림프종은 매우 드물지만 실제 거의 모든 신체 장기에 발생하는 것으로 알려져 있는데, 가장 흔한 부위인 위 외에도 폐, 갑상선, 침샘, 눈물샘에 발생하고, 드물게 안구, 유방, 방광, 신장, 흉선 등에도 보고된 바 있다. MALT 림프종은 오랜 기간동안 원격 전이하지 않고 국소 병변으로 남아 있는 특징이 있어 치료 방향 또한 국소 병변의 치료에 집중되며, 예후도 림프절 기원의 림프종에 비해 양호한 것으로 알려져 있다. 본 저자 등은 자궁 내막에 원발성으로 발생한 MALT 림프종 1예를 경험하였기에 문헌 고찰과 함께 이를 보고하고자 한다. Mucosa associated lymphoid tissue (MALT) lymphoma can rarely develop primarily in extranodal sites other than stomach which is the most common site for it. Other rare primary sites are small intestine, colorectum, esophagus, lung, thyroid, salivary gland, lacrymal gland, breast and skin. MALT lymphoma represents a distinct clinicopathologic features: it is usually localized to their original site for a long time and shows much more favorable prognosis than lymphoma at other site, but some MALT lymphoma can arise simultaneously or successively in different organ or give rise to another MALT lymphoma of other organ and can be multifocally disseminated or recurred. We report a very rare case of high grade B-cell lymphoma of mucosa associated lymphoid tissue (MALT) of the uterine endometrium, which was confirmed by immunohistochemical assay.

MVC알고리즘 이용한 효율적인 MPEG 동영상분할

전대홍,김영호,강대성 동아대학교 정보기술연구소 2002 情報技術硏究所論文誌 Vol.9 No.2

This paper proposes the mean value comparison algorithm(Mean Value Comparative Algorithm) for MPEG video segmentation. Shot detection that segments MPEG video sequence is important work and first step for video index and retrieval as being most basic. Usually, segmentation algorithm used much has a defect that occurs a error detection according to screen change of camera lights' flash etc. or fast movement of body or movement of camera, because of comparing former frame with present frame. Therefore I appropriated Shot point that detects at traditional algorithm and distinguished once more through comparing its mean value with abutting frames in this paper. I could detect more corrective shot than traditional algorithm by experiment result.

APPLE II 를 이용한 터미날 에뮬레이션

전병천,김대영 忠南大學校 産業技術硏究所 1986 산업기술연구논문집 Vol.1 No.2

In order to utilize the APPLEⅡ personal computers, we have added the communication and editing functions to the APPLEⅡ. The added system is of low cost and is capable of local-editng, up-loading, down-loading and processing batch jobs.

직렬 리액터를 이용한 계통연계형 태양광 발전 시스템

金大均,鄭春炳,全基英,李丞煥,吳鳳煥,李勳九,金容珠,韓慶熙 명지대학교 산업기술연구소 2005 産業技術硏究所論文集 Vol.24 No.-

Since the residential load is an AC load and the output of solar cell is a DC power, the photovoltaic system needs the DC/AC converter to utilize solar cell. In case of driving to interact with utility line, in order to operate at unity power factor, converter must provide the sinusoidal wave current and voltage with same phase of utility line. Since output of solar cell is greatly fluctuated by insolation, it is necessary that the operation of solar cell output in the range of the vicinity of maximum power point. In this paper, DC/AC converter is three phase PWM converter with smoothing reactor. And then, feedforward control used to obtain a superior characteristic for current control and digital PLL circuit used to detect the phase of utility line.

신축학교 실내공기질이 초등학생들의 인지기능에 미치는 영향

김태섭,김선주,박시영,전만중,김규태,김창윤,정종학,백성옥,사공준 대한산업의학회 2007 대한직업환경의학회지 Vol.19 No.1

목적: 신축초등학교와 대조학교를 선정하여 교실 내 포름알데히드와 TVOCs를 측정하고 컴퓨터 신경행동검사를 이용하여 실내공기 오염물질이 학생들의 인지기능에 미치는 영향을 평가하였다. 방법: 신축초등학교 5학년 71명을 실내공기 오염물질 노출군으로 하고, 개교한지 12년째인 대구시의 일개 초등학교 5학년 2학급 63명을 대조군으로 하여 실내공기 오염물질농도 측정 및 컴퓨터 신경행동검사를 실시하였다. 결과: 신축학교에서 의도적으로 창문을 개방한 학급에서 1교시 포름알데히드 농도는 34.6 ㎍/㎥, 4교시에는 27.3 ㎍/㎥, 창문을 개방하지 않은 학급에서 1교시 80.2 ㎍/㎥, 4교시 127.1 ㎍/㎥, 대조학교에서는 2학급 각각 1교시에 12.6 ㎍/㎥, 7.5 ㎍/㎥, 4교시에 19.8 ㎍/㎥, 25.2 ㎍/㎥였다. TVOCs의 경우 신축학교의 의도적으로 창문을 개방한 학급에서 1교시에 농도는 487.2 ㎍/㎥, 4교시에 428.2 ㎍/㎥, 창문을 개방하지 않은 학급에서 1 교시에 농도는 1,283.5 ㎍/㎥, 4교시에 1,715.4 ㎍/㎥, 대조학교의 경우 2학급에서 각각 1교시에 농도는 240.9 ㎍/㎥, 150.8 ㎍/㎥, 4교시에 농도는 371.9 ㎍/㎥, 448.0 ㎍/㎥였다. 부호숫자 짝짓기의 평균반응시간은 대조학급이 1교시에 2,585 msec에서 4교시에 2,459 msec으로 감소한 반면 신축학교의 창문을 의도적으로 개방한 학급은 2,343 msec에서 2,510 msec으로, 평소대로 수업한 학급은 2,340 msec에서 2,563 msec으로 반응시간이 각각 167 msec, 223 msec 증가하였다. 1교시의 부호숫자 짝짓기 의 반응시간을 100%로 했을 때 창문을 의도적으로 개방 한 학급은 4교시에 5.9% 증가하였고(p<0.01), 평소대로 수업한 학급은8.3% 증가하였다(p<0.01). 반면에 대조학급은 4교시에 5.0% 감소하였다(p<0.01). 결론: 향후 학교의 실내공기질의 안전성 평가는 샘플링 된 공기의 오염수준의 측정뿐만 아니라 학생들의 건강영향도 함께 고려되는 것이 바람직할 것이다. Objectives: Most studies on the indoor air quality of newly built schools have focused only on the number of schools exceeding a standard or on subjective symptoms, such as sneezing, irritated eyes and an irritated nose. However, there has been no report on how poor indoor air quality affects children's academic performance. This study evaluated the effects of indoor air quality on the neurobehavioral performance of elementary school children. Methods: This study measured the indoor air pollutants and compared children's performance, using a computerized neurobehavioral test, between a newly built and a 12-year-old school. In addition, a questionnaire was administered regarding the indoor air quality related symptoms of children in a newly built and a 12-year-old school. Results: In the newly built school, the formaldehyde levels in the 1^(st) and 4^(th) classes with an open window were 34.6 and 27.3 μg/㎥, respectively. The levels in the 1^(st) and 4^(th) classes with the window closed were 80.2 and 127.1 μg/㎥, respectively. In the 12-year-old school, the formaldehyde levels in 1^(st) and 4^(th) class with open and closed window were 12.6 and 7.5 μg/㎥, and 19.8 and 25.2 μg/㎥, respectively. With respect to total volatile organic compounds, the levels in the 1^(st) and 4^(th) classes with the window open in the newly built school were 87.2 and 428.2 μg/㎥, respectively. In the 1^(st) and 4^(th) classes with the window closed, the total volatile organic compounds were 1,283.5 and 1,715.4 μg/㎥, respectively. In the 12-year-old school, the total volatile organic compounds were 240.9 and 150.8 μg/㎥, and 371.9 and 448.0 μg/㎥ in the 1^(st) and 4^(th) classes, respectively. In the case of a newly built school, the performance of the students in the neurobehavioral test in the 4^(th) class with the window closed was 8.3% lower than for those in the 1^(st) class with the window closed, but was only 5.9% lower when the windows were open. There was a statistical significant difference in the total numbers of symptoms between the two schools. Conclusions: These results suggest a proper evaluation of the indoor air quality within schools is required into both the level of contamination and the health effects of these contaminants toward children.

고지혈증에 대한 Lovastatin (Mevacor ??)의 치료효과

김영건,전은석,구대회 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.2

To evaluate the lipid lowering effect of lovastatin a hydroxy methylglutaryl coenzyme A(HMG CoA) reductase, 18 hyperlipidemic patients were medicated with Mevacor^?? (20-40mg q. d) for 4 weeks in Chungnam National University Hospital. The results were as follows : 1. The serum total cholesterol decreased after 2 and 4 weeks of medication. (278±29 vs 220±37, 190±29mg/dl, p<0.05). 2. The serum triglyceride also decreased after medication(244±102 vs 210±118, 158±72 mg/ml, p<0.05). 3. The HDL cholesterol increased after 4 weeks medication(47±15 vs 60±16mg/dl, p<0.05). 4) The calculated LDL cholesterol decreased after medication(183±29 vs 125±39, 99±28 mg/dl, p<0.05). 5. There were no significant side effects except headache in one patient. As the results above, lovastatin(Mevacor^??)is a safe and very effective lipid lowering agent for the treatment of hyperlipidemia.

A Study on Protection of Maternal Antibody against Hantavirus in Rats

우영대,--,--,--,--,-- 대한의생명과학회 2005 Biomedical Science Letters Vol.11 No.1

The etiologic agents of haemorragic fever with ranal syndrom (HFRS) in Korea are Hantaan and Seoul virus in the genus Hantavirus, family Bunyaviridae. In order to elucidate the role of maternal immunity to Hantavirus infection in rats, the protective effect of the maternal antibody were studies by using rats experimentally infected with Seoul virus strain HR80-39. Antibody titers of sera and viral antigen against Seoul virus were investigated by indirect immunofluorscence antibody technique (IFA). The dam sera had IFA antibody titers ranging from 1:128 to 1:1,024 after parturition. In fetuses, IFA antibody titers ranged from 1:16 to 1:64 just after birth, increased to peak titers ranged from 1:256 to 1:1,024 in the 2nd week after birth. Challenged newborn rats had IFA antibody titers ranging from 1:64 to 1:1,024 after inoculation. No viral antigen was detected in lungs or other organs of the newborn rats. The maternal antibody to Seoul virus was transferred prenatally through placenta and postnatally via colostrum from immune dams to their offspring. These results demonstrated that maternal antibody to Seoul virus was quite effective in protecting newborn rats against same virus infection.

전립선대비증 평가에서 이행대 용적지수와 증상점수 및 요류속도와의 상관관계

김철성,전상준,정치영,소영석,노준,장대수 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2

Purpose : otal prostate volume has been known to be poorly correlated with other parameters used to assess benign prostatic hyperplasia(BPH), including international prostatic symptom score(IPSS), peak flow rate(Qmax). This study was aimed to investigate the possible correlation between transition zone index(TZI), IPSS and Qmax in patients with clinical benign prostatic hyperplasia(BPH). Materials and methods : From September 1999 to December 2000, A total of 95patients with clinical BPH were evaluated total prostate volume(TV), transition zone volume(TZV), TZI, IPSS and Qmax. TZI was determined as the ratio between transition zone volume(TZV) and total prostate volume(TV). Results : The relationships between IPSS and TV, TZV, and TZI were not statistically significant. A statistically significant relationship was observed between TZV, TZI and Qmax and between TV, TZV, TZI and age. Conclusion : These results suggest that TZV, TZI may not be a useful method to assess symptom severity in BPH patients but may be limited clinical parameters.