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NGO, Chi Thanh,NGUYEN, Thi Ngoc Mai,NGUYEN, Duy Dat,LE, Hoang Ba Huyen,LE, Van Cuong,LE, Thi Binh Korea Distribution Science Association 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.9
The study aims to investigate factors affecting enterprise's satisfaction and loyalty toward the Social Security's online public services, looking at the case of Thanh Hoa province, Vietnam. This study employs samples with 216 enterprises that use online public system of Thanh Hoa province's Social Security. The research model is closely linked to the SERVQUAL model developed by Parasuraman, Zeithaml and Berry (1988). We propose 23 scales that constitute the quality of service, three scales that constitute Customer Satisfaction and three components that constitute Customer Loyalty. This study use the tool of Exploratory Factor Analysis (EFA), Cronbach's Alpha test, Confirm Factor Analysis (CFA) and Structural Equation Modeling (SEM) in order to address the question of satisfaction and loyalty. The result shows that the factor with the most impact is Reliability, next is Capacity of staffs, Tangibles, Attitude of staffs, and the least impacting factor is Empathy; moreover, the results also show that Satisfaction has a strong impact on Customer Loyalty. The findings of this study suggest that Thanh Hoa province's Social Security should: (i) strengthen the reliability of online service system; (ii) build capacity for staffs; (iii) develop the responsiveness of electronic transactions systems; and (iv) improve the empathy of staffs.
Cuong-Le, Thanh,Nguyen, Khuong D.,Le-Minh, Hoang,Phan-Vu, Phuong,Nguyen-Trong, Phuoc,Tounsi, Abdelouahed Techno-Press 2022 Advances in nano research Vol.12 No.5
This study explores the linear and nonlinear solutions of sigmoid functionally graded material (S-FGM) nanoplate with porous effects. A size-dependent numerical solution is established using the strain gradient theory and isogeometric finite element formulation. The nonlinear nonlocal strain gradient is developed based on the Reissner-Mindlin plate theory and the Von-Karman strain assumption. The sigmoid function is utilized to modify the classical functionally graded material to ensure the constituent volume distribution. Two different patterns of porosity distribution are investigated, viz. pattern A and pattern B, in which the porosities are symmetric and asymmetric varied across the plate's thickness, respectively. The nonlinear finite element governing equations are established for bending analysis of S-FGM nanoplates, and the Newton-Raphson iteration technique is derived from the nonlinear responses. The isogeometric finite element method is the most suitable numerical method because it can satisfy a higher-order derivative requirement of the nonlocal strain gradient theory. Several numerical results are presented to investigate the influences of porosity distributions, power indexes, aspect ratios, nonlocal and strain gradient parameters on the porous S-FGM nanoplate's linear and nonlinear bending responses.
Risk Factors Affecting Equipment Management in Construction Firms
Cuong Phu PHAM,Phong Thanh NGUYEN,Phuong Thanh PHAN,Quyen Le Hoang Thuy To NGUYEN,Loan Phuc LE,My Tien Ha DUONG 한국유통과학회 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.11
Mechanization and automation constitute an essential stage in the production and operation of any company, as one of the determinants of increase in labor productivity and decrease in product price, while significantly contributing to shortening of the lead time. Businesses are, therefore, able to quickly put projects into operation, improving economic efficiency, quality, and aesthetics, which speeds up the national economic growth. For the construction industry to be the most effective, modern construction equipment is a necessity. It is one of the five main resources of a construction project. Thus, effective construction equipment management contributes to the success of a project and benefits the relevant construction companies economically. This paper presents the critical risk factors affecting equipment management and proposes suitable solutions. The questionnaire-based survey with experienced experts in the construction sector on the management of the likelihood and consequence of risk factors revealed thirty-two risks for equipment management in construction companies. These factors fell into six groups: (i) site organization-related risks; (ii) management-related risks; (iii) owner-related risks; (iv) supplier-related risks; (v) legal risks, and (vi) site condition-related and external risks. The results showed that management-related factors contributed to the most significant risks and problems for equipment management in construction companies.
( Thanh Hoa Le ),( Tran Binh Le ),( Thanh Huong Thi Doan ),( Dong Van Quyen ),( Kim Xuyen Thi Le ),( Viet Cuong Pham ),( Mitsuru Nagataki ),( Haruka Nomura ),( Yasunori Ikeue ),( Yoshiya Watanabe ),( 한국미생물 · 생명공학회 2011 Journal of microbiology and biotechnology Vol.21 No.4
Avian influenza virus vaccines produced in oil-emulsified inactivated form with antigen content of at least 160 hemagglutinin units (HAU) induced immunity in birds. However, in addition to enhancing the effect of the adjuvant(s), other additional supplemented biological compounds included in inactivated vaccines could produce higher levels of antibody. We examined in chickens, Vietnamese ducks, and muscovy ducks the adjuvant effect of Sophy β-glucan (SBG), a β-1,3-1,6 glucan produced by the black yeast Aureobasidium pollulans strain AF0-202, when administered with an avian influenza H5 subtype vaccine. In Experiment 1, 40 chickens (ISA Brown hybrid), allocated to four groups of ten each, were immunized with Oil-H5N1(VN), Oil-H5N1(CN), Oil-H5N2(CN), and saline (control group), respectively. In Experiment 2, chickens (ISA Brown hybrid), muscovy ducks (French hybrid), and Vietnamese ducks (indigenous Vietnamese) were used to further assess the effect of SBG on immunogenicity of the Oil-H5N1(VN) Vietnamese vaccine. ELISA and hemagglutination inhibition (HI) assays were used to assess the antibody response. The H5 subtype vaccines initiated significantly higher immune responses in the animals dosed with SBG, with 1.0-1.5 log2 higher HI titers and 10-20% ELISA seroconversion, compared with those not dosed with β-glucan. Notably, some of the animals dosed with SBG induced HI titers higher than 9.0 log2 following boosting immunization. Taken together, our serial studies indicated that SBG is a potential effector, such as enhancing the immune response to the H5 vaccines tested.
Thanh Khiem Nguyen,Ham Hoi Nguyen,Tuan Hiep Luong,Kim Khue Dang,Van Duy Le,Duc Dung Tran,Van Minh Do,Hong Quang Pham,Hoan My Pham,Thi Lan Tran,Cuong Thinh Nguyen,Hong Son Trinh,Yosuke Inoue 한국간담췌외과학회 2024 Annals of hepato-biliary-pancreatic surgery Vol.28 No.1
Backgrounds/Aims: Pancreaticoduodenectomy (PD) is the only radical treatment for periampullary malignancies. Superior mesenteric artery (SMA) first approach combined with total meso-pancreas (MP) excision was conducted to improve the oncological results. There has not been any previous research of a technique that combines the SMA first approach and total MP excision with a detailed description of the MP macroscopical shape. Methods: We prospectively assessed 77 patients with periampullary malignancies between October 2020 and March 2022 (18 months). All patients had undergone PD with SMA first approach combined total MP excision. The perioperative indications, clinical data, intra-operative index, R0 resection rate of postoperative pathological specimens (especially mesopancreatic margin), postoperative complications, and follow-up results were evaluated. Results: The median operative time was 289.6 min (178−540 min), the median intraoperative blood loss was 209 mL (30−1,600 mL). Microscopically, there were 19 (24.7%) cases with metastatic MP, and five cases (6.5%) with R1-resection of the MP. The number of lymph nodes (LNs) harvested and metastatic LNs were 27.2 (maximum was 74) and 1.8 (maximum was 16), respectively. Some (46.8%) patients had pancreatic fistula, but mostly in grade A, with 7 patients (9.1%) who required re-operations. Some 18.2% of cases developed postoperative refractory diarrhea. The rate of in-hospital mortality was 1.3%. Conclusions: The PD with SMA first approach combined TMpE for periampullary malignancies was effective in achieving superior oncological statistics (rate of MP R0-resection and number of total resected LNs) with non-inferior short-term outcomes. It is necessary to evaluate survival outcomes with long-term follow-up.
Anti-inflammatory Triterpenes and Glyceryl Glycosides from Kandelia candel (L.) Druce
Le Duc Dat,NGUYEN PHUONG THAO,BUIHUU TAI,Bui Thi Thuy Luyen,양서영,김소현,구정은,고영상,Nguyen The Cuong,Nguyen Hoai Nam,Nguyen Van Thanh,Phan Van Kiem,Chau Van Minh,김영호 한국생약학회 2015 Natural Product Sciences Vol.21 No.3
Phytochemical investigation of Kandelia candel resulted in the isolation of six triterpenes (1 - 5) and two glyceryl glycosides (6 and 7) and their structures were determined by comparing the spectroscopic data with those of reported values. In present study, we described the inhibitory effects of fractions and isolated compounds from K. candel on pro-inflammatory cytokines (IL-12 p40, IL-6, and TNF-a) production in lipopolysaccharide (LPS) stimulated bone marrow-derived dendritic cells (BMDCs). Results indicated that compounds 3, 6, and 7 showed potent inhibition on IL-6 production (IC50 values at less than 0.5 mM, respectively). Meanwhile, compounds 6 and 7 exhibited strong inhibitory effects on the production of TNF-a (IC50 values of 1.7 ? 0.1 and 5.5 ? 0.2 mM). Compounds 1 and 3 were also showed the inhibitory effects on IL-12 p40 production (IC50 values of 8.9 ? 0.4 and 3.3 ? 0.1 mM, respectively).
Van Thanh, Nguyen,Jang, Hyun-Jae,Vinh, Le Ba,Linh, Kieu Thi Phuong,Huong, Phan Thi Thanh,Cuong, Nguyen Xuan,Nam, Nguyen Hoai,Van Minh, Chau,Kim, Young Ho,Yang, Seo Young Elsevier 2019 Bioorganic chemistry Vol.88 No.-
<P><B>Abstract</B></P> <P>In a search for anti-inflammatory activity in resources from Vietnamese mangroves, we found that a methanolic extract from the leaves of <I>Calophyllum inophyllum</I> (CIL) showed significant anti-inflammatory effects <I>in vitro</I>. Using various chromatographic techniques, we subsequently isolated 12 compounds (<B>1</B>–<B>12</B>) from a methanolic extract of CIL, including two novel compounds (<B>1</B>–<B>2</B>). The inhibitory effects of these compounds on lipopolysaccharide-induced nitric oxide (NO) production in RAW264.7 cells were also evaluated. Compound <B>1</B> significantly suppressed NO production (IC<SUB>50</SUB> = 2.44 ± 0.88 µM), the secretion of pro-inflammatory cytokines (including interleukin-1 beta and tumor necrosis factor alpha), and the expression of inducible nitric oxide synthase through downregulation of nuclear factor-kappa-B signaling cascades. These results suggest that <I>C. inophyllum</I> leaves might be a useful resource for the development of drugs for the treatment of inflammation.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Twelve compounds were isolated from Vietnamese mangrove <I>Calophyllum inophyllum</I>. </LI> <LI> Two new compounds <B>1</B> and <B>2</B> were determined by spectroscopic methods. </LI> <LI> Compound <B>1</B> showed significant anti-inflammatory activity. </LI> <LI> These results suggested that <I>C. inophyllum</I> might useful as the anti-inflammation drug. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Nguyen, Cuong Thach,Le, Nhat-Tu,Tran, Thao Dang-Hien,Kim, Eun-Hye,Park, Sang-Sang,Luong, Truc Thanh,Chung, Kyung-Tae,Pyo, Suhkneung,Rhee, Dong-Kwon American Society for Microbiology 2014 Infection and immunity Vol.82 No.9
<P>Caseinolytic protease L (ClpL) is a member of the HSP100/Clp chaperone family, which is found mainly in Gram-positive bacteria. ClpL is highly expressed during infection for refolding of stress-induced denatured proteins, some of which are important for adherence. However, the role of ClpL in modulating pneumococcal virulence is poorly understood. Here, we show that ClpL impairs pneumococcal adherence to A549 lung cells by inducing and activating Rap1 and Rac1, thus increasing phosphorylation of cofilin (inactive form). Moreover, infection with a <I>clpL</I> mutant (Δ<I>clpL</I>) causes a greater degree of filopodium formation than D39 wild-type (WT) infection. Inhibition of Rap1 and Rac1 impairs filopodium formation and pneumococcal adherence. Therefore, ClpL can reduce pneumococcal adherence to A549 cells, likely via modulation of Rap1- and Rac1-mediated filopodium formation. These results demonstrate a potential role for ClpL in pneumococcal resistance to host cell adherence during infection. This study provides insight into further understanding the interactions between hosts and pathogens.</P>
Hoanh Su Le,Cuong Trieu,Thanh Ho,Jong-Hwa Lee,Hyun-Kyu Lee 한국인터넷전자상거래학회 2017 인터넷전자상거래연구 Vol.17 No.5
The increasing of users in social networking services in Vietnam help companies have better communication channels with customers. Nowadays, any companies can easily invest tools and human to monitor and harvest customer-generated contents not only about their own brands but also about their competitive brands on social media sites. In order utilize the value in the harvested data, certain analytic techniques are required. This paper proposed a method to apply mining social media data in the context of fastfood brands. We collected data from top fastfood chains including Lotteria, MacDonald, KFC, Vietnam Pizza Hut and Pepperonis Vietnam and applied machine learning to classify the sentiment of informal text data. The results show that applying neural network machine learning in sentiment analytics of social media text data is suitable for sentiment analytics and applicable for future data prediction in fastfood industry.