『증보산림경제』의 장류(醬類) 조리 가공에 관한 연구

김성미,이춘자 동아시아식생활학회 2004 동아시아식생활학회지 Vol.14 No.3

The "Jeungbosallimgyeongje" was literature reviewed about the manufacture of Korean sauces. Furthermore, in order to investigate the changes made by time period, other literatures, "Eumsigdimibang(1670s)", "Sallimgyeongje(1715)", "Gyuhapchongseo(1815)" and "Choson-mussangyorijebeop(1930)", were compared. The ingredients mentioned included soybeans, flour, barley, elm trees, red beans and blue beans, etc. In addition, the shapes and sizes of dried soybean paste brick were varied. "Manchojang", which designated the kind of hot pepper paste, appeared in this book for the first time. During its manufacturing process, it was characteristic to add dried bean paste, sea kelp and fish to produce a novel and higher quality product. From the above mentioned books, we found out that Koreans used only the soybeans and Chinese a mixture of buckwheat, flour and barley in addition to soybeans to make their traditional sauces. According to the "Gyuhapchongseo", there was a slight difference in ingredients to add for the manufacture of fish sauce, but the manufacturing methods and the one year period needed for maturing the ingredients were the same. However, in the "Chosonmussangsinsikyrijebop", fish sauce and meat sauce were classified separately and their manufacturing methods were different as well. In conclusion, the ingredients of used for the sauces recorded in "Jeungbosallimgyeongje" were various and at first hot pepper sauce made from "Manchojang" appeared and additionally red peppers were added to five kinds of Korean paste and red pepper powder were added to two kinds of Korean paste. The manufacturing method of the sauces changed according to time period, for example, only soybean has been used in Korean traditional sauces and other ingredients used as for Chinese ones eventually disappeared.

서양음악 이론사를 위한 원전 연구(1)유클리드의 Division of A Monochord

金春美 漢陽大學校 音樂硏究所 1991 音樂論壇 Vol.5 No.-

서양음악 이론사를 위한 원전 연구(2): 피타고라스와 음악이론

金春美 漢陽大學校 音樂硏究所 1992 音樂論壇 Vol.6 No.-

구멍갈파래 엽상체의 a 형광유도과정의 특성과 수은의 영향

김미경,강수경,이춘환,이진범,정익교 동의대학교 기초과학연구소 1995 基礎科學硏究論文集 Vol.5 No.1

The effects of mercury on the photosynthetic machinery of Ulva pertusa Kjellman were examined by measuring oxygen evolution, pigment contents, and fluorescence induction process. By increasing the concentration of added HgCl₂upto 0.6 ppm, oxygen evolution rate and pigment contents were decreased gradually. Chlorophyll α/b ratio was also decreased, suggesting that chlorophyll α was decreased (probable degraded) more rapidly than chlorophyll b by the treatment of mercury. Overall pattern of the fluorescence induction curve was very similar to that measured from terrestrial plant leaves. However, several characteristic differences observed: (1) fluorescence intensity decreased very rapidly after P(peak), (2) D(dip)-P increase was significantly reduced when measured 30 sec after a saturation pulse, and (3) Fmax was decreased when measured again 30 sec after a first measurement by using a saturation pulse. Due to the second and third characteristics, at least 30 min dark interval was required before starting an additional measurement using a sample. When the mercury concentration was increased, Fp (fluorescence intensity at P) was decreased gradually, but Fi(the intensity at inflection) did not increased. The decrease in Fp could be explained by the inhibition of mercury at a site near oxygen evolving complex. By the addition of 0.2 ppm HgCl₂, Fp was increased slightly without significant changes in ID pattern. This result suggests that the inhibition site of mercury at the electron transport chain on the reducing side of PSⅡ is not the Q_B or DCMU binding site. When the mercury concentration was increased, Fo was decreased slightly, but Fmax, (Fv)m/Fmax, qQ and qN was decreased significantly. By the addition of mercury more than 0.6 ppm, photosynthetic activities was almost completely blocked but pigment contents was stayed the same.

신경섬유종에 동반된 양측성 갈색세포종 1예

김홍승,김윤미,신영구,김일회,조미연,정춘희 대한내분비학회 1997 Endocrinology and metabolism Vol.12 No.3

Pheochromocytoma is originated from chromaffin cell of sympathetic nervous system and associated with other disease, such as neurofibromatosis, duodenal carcinoid, medullary thyroid cancer and parathyroid adenoma. Especially, pheochromocytoma is developed more than 50% in neurofibromatosis associated with hypertension. In such cases, several clinical features documented as more frequent bilateral phochromocytoma, more associated with other neuroendocrine tumors and thus more poor prognosis. We can observe the sustained hypertension despite of surgical resection of tumors in pheochromocytoma cases. One of the possible reason of post operative sustained hypertension is the pheochromocytoma originated from minor organ of Zukerkandl that was not resected during operation. Untreated or delayed treated cases with pheochromocytoma were often expired by complication of hypertension such as cerebrovascular hemorrhage, myocardial infarction, etc. Thus, in neurofibromatosis with hypertension, screening of pheochromocytorna is very important for the early detection of tumor and more favorable prognosis. Recently, We experienced a case of neurofibromatosis associated with bilateral pheochromocy- toma expired by cerebral hemorrhage during operation, so we report the case with literature review. (J Kor Soc Endocrinol 12:478-484, 1997)

Regulation of Metalloprotease VvpE Production by Quorum-sensing System in Vibrio vulnificus

Choon-Mee Kim · Joon-Seob Song · Sung-Heui Shin 조선대학교 의학연구원 2008 The Medical Journal of Chosun University Vol.33 No.2

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Quantitative Meaurement of Vibrio vulnificus Hemolysin Production

Kim, Choon-Mee,Shin, Sung-Heul 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.2

Vibrio vulnificus cytolysin/hemoIysin (VvhA) is produced during the early growth phase and abruptly inactivated in the late growth phase via self-oligomerization, which indicates that actual VvhA production, especially during the late growth phase, cannot be accurately determined by conventional functional assay methods, which measure hemolytic activity by only active VvhA monomers, In this study, we attempted to evaluate the usefulness of immunological methods for the quantitative determination of actual VvhA production, Although several electrophoretic methods were employed, the Western blot methods were not suitable for the quantitative measurement of VvhA production because of the presence of multiple or gigantic VvhA forms. The dot blot method was able to measure quantitatively actual VvhA production consistent with the transcription level of the whA gene. Accordingly, we recommend the Dot-blot method as a simple useful immunological method for the quantitative measurement of actual VvhA production.

Coinfection with Rickettsia monacensis and Orientia tsutsugamushi

( Choon-mee Kim ),( Dong-min Kim ),( Na-ra Yun ) 대한인수공통전염병학회 2019 창립총회 및 학술대회 초록집 Vol.2019 No.1

Introduction: Rickettsia monacensis and Orientia tsutsugamushi are are bacteria of the genus, Rickettsia, which causes fever, rash, and eschar formation, a risk factor for which includes outdoor activities. Case report: A 75-year-old female patient presented with fever, with subsequent findings of a rash and eschar. To confirm the diagnosis of scrub typhus, polymerase chain reaction (PCR) testing targeting a 56 kDa region of the Orientia tsutsugamushi genome was performed, which identified the Boryong genotype. In addition, a Pan-Rickettsial real time PCR test was PCR positive, and a nested PCR test using a Rickettsia-specific partial outer membrane protein A (rOmpA) confirmed R. monacensis. Conclusion: This is the first case of a patient who was suspected to have scrub typhus due to rash and eschar, and was found to be coinfected with O. tsutsugamushi and R. monacensis through molecular testing.

Change of Vibrio vulnificus Metalloprotease VvpE Production by Temperature and Salinity

Kim, Choon-Mee,Shin, Sung-Heui The Korean Society for Microbiology 2011 Journal of Bacteriology and Virology Vol.41 No.3

Vibrio vulnificus, a gram-negative halophilic marine bacterium and opportunistic pathogen, must withstand various environmental changes, especially the simultaneous change of temperature and salinity (SCTS) from $25^{\circ}C$/2.5% to $37^{\circ}C$/0.9% upon entering the human body. Previous studies have suggested that temperature and salinity may affect the production of metalloprotease VvpE via the LuxS-mediated autoinducer-2 quorum sensing system (AI-2-QSS). However, this hypothesis remains to be verified through coherent experiments. In this study, SCTS stimulated V. vulnificus growth with no increase in total growth levels. The SCTS-mediated prolongation of the stationary growth phase resulted in a significant increase in growth phase-dependent luxS and vvpE transcriptions; however, SCTS did not affect luxS or vvpE transcription levels during the exponential growth phase. SCTS also advanced extracellular VvpE production, which was consistent with vvpE transcription and V. vulnificus growth. SCTS-mediated modulation of vvpE expression was slightly attenuated but still observed in the background of a luxS mutation which seriously repressed vvpE expression. These results indicate that SCTS stimulates luxS and vvpE expression by stimulating V. vulnificus growth; however, the LuxS-mediated AI-2-QSS plays only a minor role, if any, in the SCTS-mediated modulation of vvpE expression.

A Ferrophilic Bacterium, Vibrio vulnificus

Choon-Mee Kim · Sung-Heui Shin 조선대학교 의학연구원 2009 The Medical Journal of Chosun University Vol.34 No.4

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