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Choi, Sang-Up,Pae, Young-Il,Rhyu, Sok-Hwan Korean Chemical Society 1985 Bulletin of the Korean Chemical Society Vol.6 No.3
The kinetic study on the bromine-exchange reaction of antimony tribromide with ${\alpha}$-phenylethyl bromide in nitrobenzene has been carried out, using Br-82 labelled antimony tribromide. The results show that the exchange reaction is first order with respect to ${\alpha}$-phenylethyl bromide, and either second or first order with respect to antimony tribromide depending on its concentration. It is also concluded that ${\alpha}$-phenylethyl bromide exchanges bromine atom with antimony tribromide much faster than other organic bromides previously examined. Reaction mechanisms for the exchange reaction are discussed.
Application of Fault Location Method to Improve Protect-ability for Distributed Generations
Sung-Il Jang,Duck-Su Lee,Jung-Hwan Choi,Yong-Cheol Kang,Sang-Hee Kang,Kwang-Ho Kim,Yong-Up Park 대한전기학회 2006 Journal of Electrical Engineering & Technology Vol.1 No.2
This paper proposes novel protection schemes for grid-connected distributed generation (DG) units using the fault location algorithm. The grid-connected DG would be influenced by abnormal distribution line conditions. Identification of the fault location for the distribution lines at the relaying point of DG helps solve the problems of the protection relays for DG. The proposed scheme first identifies fault locations using currents and voltages measured at DG and source impedance of distribution networks. Then the actual faulted feeder is identified, applying time-current characteristic curves (TCC) of overcurrent relay (OCR). The method considering the fault location and TCC of OCR might improve the performance of the conventional relays for DG. Test results show that the method prevents the superfluous operations of protection devices by discriminating the faulted feeder, whether it is a distribution line where DG is integrated or out of the line emanated from the substation to which the DGs are connected.
( Sung Hoon Choi ),( Mi Sol Lee ),( Shin Won Hwang ),( Jun Yong Park ),( Seung Up Kim ),( Sang Hoon Ahn ),( Weon Sang Ro ),( Kwang Hyub Han ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.-
Objectives: HIF-1β (ARNT) formed dimerization of HIF-1α, involved in various aspects of cancer biology, including proliferation and survival under hypoxic condition. This is an in vitro study that investigated the mechanism by which small interference HIF-1β (siHIF-1β) inhibits HIF-1α dimerization and thus it lead to suppress tumor cell growth. Method: Three HCC cell lines (HepG2, Huh 7 and Hep3B) were transfected with HIF-1β coding siRNA and cultured under hypoxic conditions (1% O2, 24 hours). Following transfection, the expression levels of HIF-1β , HIF-1α, and growth factors were examined through immuno-blotting. In addition, tumor growth was measured by MTT assay and tumor activity was measured by TUNEL, tumor invasion and migration assay. Results: The inhibition of HIF-1β by small interference RNA (siHIF-1β) led to suppression of tumor cell growth through inhibition of HIF dimerization under hypoxia condition. This effect was increased and maximized at 48 hrs after treatment of HIF-1β coding siRNA. Inhibition of HIF dimerization through treatment of siHIF-1β also regulated the expression of tumor growth related factors (VEGF, EGF and HGF). Inhibition of HIF- dimerization precluded tumor invasion and migration in variable HCC cell lines. Conclusions: Inhibition of HIF dimerization by siHIF-1β may lead to anti-tumor effects in a hypoxic condition of tumor environment.
Choi In‐Hag,Choi Sung‐Up,Son Jin‐Sung,Jang Woo‐Whan,Chung Tae‐Ho 한국곤충학회 2021 Entomological Research Vol.51 No.2
This study was aimed to compare the antioxidant and cytoprotective effects of hot‐water and enzyme‐extracted constituents of Protaetia brevitarsis seulensis powder. The products of enzymatic extraction had 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH)‐radical‐scavenging activity, cytotoxic effects, and provided cytoprotection against H2O2 and intracellular reactive oxygen species. Enzymatic extraction improved DPPH‐radical‐scavenging activity relative to hot‐water extraction (P < 0.05), with inhibition rates of 33% at 500 μg/mL and 35% at 1000 μg/mL. Cell viability ranged from 100 to 122%, and was higher for hot‐water than for enzymatic extraction (P > 0.05). Hot‐water extraction achieved greater cytoprotection against H2O2 than enzymatic extraction. However, enzymatic extraction achieved greater antioxidant and cytoprotective activity against reactive oxygen species than hot‐water extraction. These results provide evidence of the antioxidant and cytoprotective effects produced by enzymatic extraction of the active ingredients from Protaetia brevitarsis seulensis powder.
( Sung Won Lee ),( Jonggi Choi ),( Seung Up Kim ),( Young-suk Lim ) 대한간학회 2021 Clinical and Molecular Hepatology(대한간학회지) Vol.27 No.3
Over the past several decades, entecavir (ETV) and tenofovir disoproxil fumarate (TDF) have remained the first-line antiviral agents in several international guidelines. These two antiviral agents have shown similar short to intermediateterm efficacy, including virologic, biochemical, serologic, and histologic responses. However, huge controversies regarding the antiviral efficacy of ETV and TDF in preventing the development of hepatocellular carcinoma (HCC) still exist. In this review, we summarized recent studies that compared the treatment efficacy of ETV and TDF in terms of HCC development. (Clin Mol Hepatol 2021;27:402-412)
Choi, Jung-Yoo,Lee, Hyo-Jung,Jang, Jae-Up,Yeo, In-Sung Ovid Technologies (Wolters Kluwer) - Lippincott Wi 2012 Implant dentistry Vol.21 No.2
<P>The aim of this study was to investigate whether bioactive surfaces were more favorable to bone than bioinert surfaces by evaluating bone responses around two commercial dental implants.</P>
Choi, Sang-Up,Pae, Young-Il Korean Chemical Society 1982 Bulletin of the Korean Chemical Society Vol.3 No.4
The kinetic study on the bromine-exchange reaction of antimony tribromide with t-butyl bromide in nitrobenzene or 1,2,4-trichlorobenzene has been carried out, using Br-82 labelled antimony tribromide. The results show that the exchange reaction is first order with respect to t-butyl bromide and 1.5th order with respect to antimony tribromide. It is assumed that the 1.5th order indicates the coexistance of first- and second-order kinetics. Reaction mechanisms for the exchange reaction are proposed.