선반 기어박스의 기어열 - 축계 진동 해석 및 저감에 관한 연구

최영휴,박선균,배병태,정택수,김청수 한국공작기계학회 2001 한국공작기계학회 춘계학술대회논문집 Vol.2001 No.-

In this study, torsional and lateral vibrations of a gear box transmission system were analyzed theoretically using some mathematical models and examined to determine the causes of its excessive vibrations. As the results, it was found there exist possibility of resonance between gear mesh frequencies and lateral vibration mode of the transmission shaft during the third shifting mode operation. In order to avoid this resonance, we proposed changing the arrangement of gears on the transmission shaft. The measured vibration levels of the improved gear box were dramatically reduced. These results may be helpful to design a machine tool gear box with low noise and vibration.

발생기 랫드의 십이지장점막 점액질에 대한 조직화학적 연구

최병태,조운복 부산대학교 유전공학연구소 1996 분자생물학 연구보 Vol.12 No.-

The Changes of mucosubstances in the duodenal mucosa of developing rats were investigated by conventional methods. On the 15 and 17 day-old fetal rat, neutral mucosubstances were observed in the stratified epithelium of the duodenum, whereas both neutral mucosubstances and sialomucins were demonstrated in the oligomucous cells on 17 day-old fetal rat. 'The brush border contained neutral mucosubstances and sialomucins from 19 day-old fetal rat, and thereafter changed the properties as a mixture of neutral mucosubstances, sialomucins and weak sulfomucins. In the goblet cells, most cells showed a mixture of neutral mucosubstances and strong sulfomucins front 19 day- old fetal rat, but a few cells contained neutral ones only. The amount of neutral and acid mucosubstances increased in the goblet cells of both villi and crypt during the suckling period. However acid mucosubstances increased in the goblet cells of crypt during the weanling period. 'Ihe Brunner's gland contained neutral mucosubstances only from 21 day-old fetal rat, but from the end of suckling period, a few cells located deep gland region contained additional strong sulfomucins.

3 차원 데이터획득 뇌 FDG-PET 의 정확도 평가

최창운,이경한,최용,임상무,김상은,이정림,홍성운,김병태 대한핵의학회 1999 핵의학 분자영상 Vol.33 No.3

Purpose: To assess the quantitative accuracy and the clinical utility of 3D volumetric PET imaging with FDG in brain studies, 24 patients with various neurological disorders were studied. Materials and Methods: Each patient was injected with 370 MBq of 2-[18F]fluoro-2-deoxy-D-glucose. After a 30 min uptake period, the patients were imaged for 30 min in 2 dimensional acquisition (2D) and subsequently for 10 min in 3 dimensional acquisition imaging (3D) using a GE AdvanceTM PET system. The scatter corrected 3D (3D SC) and non scatter-corrected 3D images were compared with 2D images by applying ROIs on gray and white matter, lesion and contralateral normal areas. Measured and calculated attenuation correction methods for emission images were compared to get the maximum advantage of high sensitivity of 3D acquisition. Results: When normalized to the contrast of 2D images, the contrasts of gray to white matter were 0.75±0.13 (3D) and 0.95±0.12 (3D SC). The contrasts of normal area to lesion were 0.83±0.05 (3D) 0.96±0.05 (3D SC). Three nuclear medicine physicians judged 3D SC images to be superior to the 2D with regards to resolution and noise. Regional counts of calculated attenuation correction was not significantly different to that of measured attenuation correction. Conclusion: 3D PET images with the scatter correction in FDG brain studies provide quantitatively and qualitatively similar images to 2D and can be utilized in a routine clinical setting to reduce scanning time and patient motion artifacts. (Korean J Nucl Med 1999;33:327-36)

Methotrexate 치료를 받고 있는 활동성 류마티스 관절염 환자에서 etanercept의 유효성과 안전성에 관한 연구

최병렬,강태영,정청일,이혜순,엄완식,김태환,전재범,유대현,배상철 대한내과학회 2004 대한내과학회지 Vol.66 No.5

목적 : 류마티스 관절염을 앓고 있는 한국인 중에 기존 DMARDs로 치료 실패하였고, 고정용량의 MTX를 복용하고 있는 환자들에 있어서 etanercept의 유효성과 안전성을 평가하고자 하였다. 방법 : 기존 DMARDs로 치료 실패한 활동성 류마티스 관절염 환자 76명을 대상으로 하여 단일군, 공개시험을 하였다. 대상 환자들은 고정용량의 MTX를 복용하면서 etanercept 25 mg을 1주일에 두 번 피하 주사하였으며 12주간 투여하였다. 유효성은 ACR 20, ACR 50,조조강직 시간으로 평가하였고, 약제의 안전성은 이상반응 등으로 평가하였다. 결과 : 대상 환자는 총 76명으로 평균 연령은 45.2세, 남자 5명, 여자 71명이었다. 84.4%인 54명이 12주째에 ACR 20을 만족하였고, 53.1%인 34명이 12주째에 ACR 50을 만족하였다. 조조 강직 시간은 치료 전 203.3분에서 치료 12주째 42.6분을 평균 74.5% 호전되었다. 가장 흔한 이상반응은 주사부위 반응이었다. 이외에도 상기도 감염, 오심, 안면부종 등이 발생하였으나 심각한 부작용은 없었다. 결론 : etanercept는 효과적이고, 안전한 류마티스 관절염 치료 방법이며 특히 MTX치료에도 불구하고 활동성인 류마티스 관절염에 기대되는 치료라고 할 수 있다. Background : This study was performed to investigate the efficacy and safety of etanercept in active rheumatoid arthritis patients with stable dose of methotrexate in Korean. Methods : In a 12 week, single arm, open trial, we assigned 76 patients with active rheumatoid arthritis who had an inadequate response to disease-modifying antirheumatic drugs. Patients received twice-weekly subcutaneous injections of etanercept 25 ㎎ while containing to receive methotrexate at a stable dose of 7.5~25 ㎎ per week. The clinical response was defined as the percent improvement in disease activity according to the criteria of the American Collage of Rheumatology (ACR) at 12 weeks. Results : Etanrecept led to significant improvements in disease activity and was safe and well tolerated. At 12 week, 84.4% of the patients receiving 25 ㎎ of etanercept achieved a 20% ACR response, and 53.1% of those receiving etanercept achieved a 50% ACR response. The most common adverse event was injection-site reaction. Other advanse events were upper respiratory infection, nausea, and facial edema, but there were no serious adverse events associated with etanercept. Conclusion : In active rheumatoid arthritis patients, etanercept was safe, well tolerated, and provided rapid clinical improvements.

피조개 발의 점액질에 대한 조직화학적 연구

최병태,조기진,홍말숙,정권순,조운복 釜山大學校 師範大學 1995 교사교육연구 Vol.31 No.-

피조개 발의 조직학적 구조는 hematoxylin-eosin염색 및 Weigert iron hematoxylin염색을, 점액질 성상을 검색하기 위하여 PAS반응, diastase 침지 후 PAS반응, alcian blue pH 2.5염색, alcian blue pH 1.0염색, alcian blue pH 2.5-PAS염색, alcian blue pH 1.0-PAS염색, aldehyde fuchsin pH 1.7-alcian blue pH 2.5염색 및 0.25% toluidine blue염색을 실시하였다. 피조개의 발은 상피, 상피하결합조직 및 근층으로 이루어져 있었으며 상피는 단층섬모원주세포로 되어 있었다. 상피하결합조직 및 근층에 다세포성 점액선인 발선이 발달되어 있었고 도관은 결합조직과 상피세포를 거쳐 개구되어 있었다. 근층은 종주근, 수직근 및 횡근섬유로 구성되어 있었다. 점액질의 조성을 보면 상피세포섬모에는 sialomucin만을, 상피세포는 중성점액질만 함유하고 있었다. 상피세포 및 결합조직내 점액도관에는 산성과 중성점액질의 혼합성인 것과 산성점액질만 함유한 것이 혼재하나 전자가 더 많았다. 산성점액질의 성상으로 보아 대부분이 강 sulfomucin을 가지며 일부는 약 sulfomucin과 sialomucin의 혼합성이었다. 대부분 발선의 점액선포에 대한 점액질 조성은 점액도관과 유사하였으나 일부 상부발선의 점액선포는 중성점액질만을, 하부발선의 점액선포는 sialomucin만을 함유하였다. This study was performed to investigate the histological structure and the histochemical properties of the mucosubstances in the foot of Anadara broughonii. For the histological structure, hematoxylin-eosin and Weigert iron hematoxylin staining were used. The mucosubstances stained with PAS, PAS-diastase, 0.25% toluidine blue, alcian blue pH 2.5, alcian blue pH 1.0, alcian blue pH 2.5-PAS, alcian blue pH 1.0-PAS, aldehyde fuchsin pH 1.7-alcian blue pH 2.5 methods. The foot was composed basically of three layers: epithelium, subepithelial connective tissue and muscular layers. The foot was lined by simple ciliated columnar epithelial cell. Foot glands consisted of multicelluear mucous acini were present in the subepithelial connective tissue and muscular layer. The mucous duct of foot glands was distributed from connective tissue to epithelial cells, and open onto the surface of the foot. The foot muscle traveled in three planes as longitudinal, transverse and vertical muscle fiber. About the properties of mucosubstances on the foot, cilia of epithelial cell contained sialomucin only and epithelial cell neutral mucosubstances only. Most of mucous duct within epithelial cells and connective tissue showed a mixture of acidic and neutral mucosubstances, while a few mucous ducts were contained acidic ones only. Among acidic mucosubstances, notable strong sulfomucin were found in most mucous cell of duct, and a mixture of weak sulfomucin and sialomucin appeared in a few cells. The properties of mucosubstances in the food glands were similiar to those of mucous duct. But a few mucous acini contained neutral mucosubstances and sialomucin only in upper and lower portion of foot gland, respectively.

한국산 닥나무류의 해부학적, 화학적 성질 및 펄프화 특성

최태호,조남석,김병로 충북대학교 농업과학기술연구소 1991 農業科學硏究 Vol.9 No.2

This study was carried out to investigate the papermaking characteristics for New Hanji (Korean Paper) products from paper mulberries. So far the bast fibers of paper mulberry species have been used as raw materials for Hanji. But, in this study, bast fibers, woody parts and whole woods are attempting for being utilize as new raw materials for special Hanji. Anatomical and chemical properties of 3 paper mulberry species and their pulping characteristics were discussed.

NC선반 기어박스의 기어열 : 축계 진동해석 Spindle System for an NC Lathe Gear Box

최영휴,박선균,배병태,정택수,김청수 한국공작기계학회 2000 한국공작기계학회 추계학술대회논문집 Vol.2000 No.-

In this study, two mathematical models are first constructed to analyze vibration characteristics of a gear train - spindle system of an NC lathe gear box. One is a lumped parameter model which is used for calculating natural frequencies of the torsional vibration, the other is a finite element model for analyzing lateral vibration and critical speeds of the spindle system. In addition, this study examines some possible resonance conditions such as gear mesh frequencies, IX shaft rpm frequencies over whole operating speed range, and so on. The results may be helpful to design a machine tool gear box with low noise and vibration.

정수처리 공정에서 철과 망간 잔류 농도에 관한 연구

최미리,서규태,문병현,이택순 7개 국립대학교 환경연구 논문집 공동발행 위원회 2003 공업기술연구 Vol.3 No.-

This study was to investigate the cause of the color and turbidity in a small-scale water treatment plant using lakes water as water supply source. Water qualities in aqueducts, in depth of the lakes and in each process were measured. And effects of prechlorination on each unit operation in the water treatment, especially on iron and manganese removal, were studied. The concentration of iron and manganese was 0.13, 0.08 mg/L in the surface water and 1.93 and 0.433 mg/L in 15 m depth of the lake. Higher iron concentration of the inlet was measured to 5.35 mg/L which was caused by the steel aqueduct corrosion. The optimun coagulation dosages of Poly Aluminum Chloride(PAC) and Liquid Aluminum Sulfate (LAS) were 17.5 mg/L and 35 mg/L. Pretreatmnet of raw water with CaCOl improved the removal efficiencies of iron and manganes. However, more efficient method for removing iron and manganes was required.

남성 건강검진 수진자에서 간기능 장애 및 비알코올성 지방간과 대사 증후군과의 관련성

최태성,유재영,김진석,장은철,박주언,김병익 순천향의학연구소 2006 Journal of Soonchunhyang Medical Science Vol.12 No.2

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21C 신지식인 양성을 위한 EQM 시스템 구축

최병태,이형민,전상봉,서승교,이우언,백종현 대구산업정보대학 2001 논문집 Vol.15 No.-

The aim of this paper is to form and to operate EQM, to say education quality management. In order to achieve the above stated purpose, the paper hypothesizes that there are similarities between enterprises and colleges in quality management. The basic method of the paper is systematic approach, modifies TQM, which is total quality management. The result is that EQM program must form and operate the feedback system for teaching and learning effect, the PSMT(project, self-study, media, team unit style teaching and learning) as a new teaching and learning method, and the digital system as an advanced mechanism, in education quality management.