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Chinmay Bhimaji Kulkarni,Srikanth Moorthy,Sreekumar Karumathil Pullara,Nirmal Kumar Prabhu,Ramiah Rajesh Kannan,Puthukudiyil Kader Nazar 소화기인터벤션의학회 2019 Gastrointestinal Intervention Vol.8 No.2
Background: To compare the outcomes in a group of patients with Budd-Chiari syndrome (BCS) managed by percutaneous recanalization with a group of patients who were managed by medical therapy alone.Methods: We retrieved the hospital records of 37 patients with BCS admitted to our facility between 2004 to 2017 and identified 24 patients (male:female = 10:14; mean age, 32.7 ± 12.5 years) who underwent percutaneous recanalization. Remaining thirteen patients (male:female = 3:10; mean age, 36.77 ± 14.71 years), were managed by medical therapy. Technical and clinical results, complications, and primary patency of percutane-ous recanalization were analyzed. Overall and symptom-free survival rates, the frequency of symptom recurrence, and the number of readmissions for recurrent symptoms were analyzed in both interventional treatment and medical therapy groups.Results: Technical success for recanalization of hepatic vein/inferior venecava by angioplasty ± stenting was achieved in 22 patients (22/24, 91.7%). Clinical success was achieved in 19 patients (19/24, 79.2%). Overall survival for patients who underwent percutaneous recanalization at 1 year and five years was 87.0% and 87.0% and for patients with medical therapy was 90.1% and 45.5%, respectively (P = 0.710). Symptom-free survival for patients who underwent percutaneous recanalization at 1 year and five year was 93.3% and 81.7% and for patients with medical therapy was 26.0% and 0%, respectively (P < 0.001). In the intervention group, 4 patients (4/24, 16.7%) were admitted for recurrent symptoms (median number of read-missions 1, range: 1–2) whereas in medically managed patients 9 patients (9/13, 69.2%) were readmitted (median number of readmissions, 2; range, 1–5) (P = 0.003).Conclusion: There was no statistically significant difference in overall survival of patients managed with percutaneous recanalization and medical therapy. Percutaneous recanalization had definite benefit in terms of fewer recurrent symptoms and hospital admissions, hence should be performed whenever technically feasible.
Chinmay Bhimaji Kulkarni,Srikanth Moorthy,Sreekumar Karumathil Pullara,Rajesh Ramaih Kannan 대한영상의학회 2013 Korean Journal of Radiology Vol.14 No.6
We report a rare case of aneurysm of splenic artery arising anomalously from the superior mesenteric artery (SMA). The aneurysm was treated successfully by coil embolization of the splenic artery distal to aneurysm and then deploying a stent graft in the SMA. A combination of stent graft and coil embolization for the treatment of aberrant splenic artery aneurysm has been reported only once. We describe the imaging findings and the endovascular procedure in this patient.
Chinmay Bhimaji Kulkarni,Srikanth Moorthy,Sreekumar Karumathil Pullara,Nirmal Kumar Prabhu,Ramiah Rajesh Kannan,Puthukudiyil Kader Nazar 소화기인터벤션의학회 2019 International journal of gastrointestinal interven Vol.8 No.2
Background: To compare the outcomes in a group of patients with Budd-Chiari syndrome (BCS) managed by percutaneous recanalization with a group of patients who were managed by medical therapy alone.Methods: We retrieved the hospital records of 37 patients with BCS admitted to our facility between 2004 to 2017 and identified 24 patients (male:female = 10:14; mean age, 32.7 ± 12.5 years) who underwent percutaneous recanalization. Remaining thirteen patients (male:female = 3:10; mean age, 36.77 ± 14.71 years), were managed by medical therapy. Technical and clinical results, complications, and primary patency of percutane-ous recanalization were analyzed. Overall and symptom-free survival rates, the frequency of symptom recurrence, and the number of readmissions for recurrent symptoms were analyzed in both interventional treatment and medical therapy groups.Results: Technical success for recanalization of hepatic vein/inferior venecava by angioplasty ± stenting was achieved in 22 patients (22/24, 91.7%). Clinical success was achieved in 19 patients (19/24, 79.2%). Overall survival for patients who underwent percutaneous recanalization at 1 year and five years was 87.0% and 87.0% and for patients with medical therapy was 90.1% and 45.5%, respectively (P = 0.710). Symptom-free survival for patients who underwent percutaneous recanalization at 1 year and five year was 93.3% and 81.7% and for patients with medical therapy was 26.0% and 0%, respectively (P < 0.001). In the intervention group, 4 patients (4/24, 16.7%) were admitted for recurrent symptoms (median number of read-missions 1, range: 1–2) whereas in medically managed patients 9 patients (9/13, 69.2%) were readmitted (median number of readmissions, 2; range, 1–5) (P = 0.003).Conclusion: There was no statistically significant difference in overall survival of patients managed with percutaneous recanalization and medical therapy. Percutaneous recanalization had definite benefit in terms of fewer recurrent symptoms and hospital admissions, hence should be performed whenever technically feasible.
Shailendra P. Banne,Arun W. Dhawale,Rajkumar B. Patil,Manjitsinh Girase,Chinmay Kulkarni,Mayuri Dake,Simran Khan 대한토목학회 2024 KSCE Journal of Civil Engineering Vol.28 No.4
The landslides or slope failures are responsible for many fatalities and significant delays in travel by blocking the roads. The soil properties such as cohesiveness, angle of internal friction, and bulk unit weight are the primary parameters responsible for land stability and should be considered for the analysis. In this paper, a Xanthan Gum (XG) biopolymer is applied to the laterite soil to improve its engineering properties. The Plaxis Limit Equilibrium (LE) 2D software is utilized to analyze the slope's stability. Four section/ paths of the Lote Parshuram Ghat in the Ratnagiri area of Maharashtra, India are taken for the analysis. It is observed that the applicationof the XG to the soil which is exposed to atmosphere (normal condition) and submerged conditions improves the strength of the soil and stability of slopes. When compared to conventional laterite soil in its natural state, the cohesiveness of soil treated with XG at concentrations ranging from 1 to 5% is greatly improved, increasing from 250.51% to 378.64%. XG-treated laterite soil has a maximum dry density of 1.72 gm/cc, 28.36% higher than untreated soil. Submerged XG-treated soil often shows a factor of safety (FOS) improvement of across 57.25%. The slope stability analysis revealed that the optimum percentage of xanthan gum as a stabilizer for the submerged slope condition is 2.7% that increase the factor of safety. In case of normal condition, the factor of safety (FOS) and strength of the laterite soil increases with the reinforced percentage of xanthan gum.