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신경화,채경연,유양자 한국조리과학회 2002 한국식품조리과학회지 Vol.18 No.1
This study was intended to investigate the breakfast habits of salaried people. Total 446 subjects (male:256 and female:190) living in Seoul participated in the study. The results obtained were as follows : About 88.8% of the respondents perceived well the importance of breakfast, but only 33.2% of them responded to have breakfast every morning. It was found that males, older people, married people and people with higher education had a tendency to have breakfast regularly. The main reasons for having breakfast were ’for nutritional intake ’(42.2%) and ’for relieving hunger’(31.3%). Cooked rice with soup (78.4%) was the most popular menu for breakfast. The time for breakfast was about 5∼15 minutes. The reasons for skipping breakfast were ’the lack of time > low appetite > habitually’, but 59.6% of the respondents answered to have cooked rice with soup if they would. The 95.6% of the respondents showed more than the ’moderate’score on nutritional knowledge. Female salaried people showed higher scores on nutritional knowledge than male counterparts. People with higher education had a better nutritional knowledge. It was found that male, older people, people with higher education, and members in the extended family or nuclear family had good eating habits. Nutritial knowledge showed a significant positive relationship with eating habits. Overall, salaried people perceived the importance of breakfast, but had poor dietary habit of skipping breakfast at 23.3%. Therefore, convenient and nutritional substitute for breakfast should be developed for salaried people.
Yoo, Chae-Kyoung,Cho, In-Cheol,Lee, Jae-Bong,Jung, Eun-Ji,Lim, Hyun-Tae,Han, Sang-Hyun,Lee, Sung-Soo,Ko, Moon-Suck,Kang, Taeyoung,Hwang, Joon-Ho,Park, Yong Sang,Park, Hee-Bok American Physiological Society 2012 PHYSIOLOGICAL GENOMICS Vol.44 No.13
<P>Clinical-chemical traits are essential when examining the health status of individuals. The aim of this study was to identify quantitative trait loci (QTL) and the associated positional candidate genes affecting clinical-chemical traits in a reciprocal F(2) intercross between Landrace and Korean native pigs. Following an overnight fast, 25 serum phenotypes related to clinical-chemical traits (e.g., hepatic function parameters, renal function parameters, electrolyte, lipids) were measured in >970 F(2) progeny. All experimental samples were subjected to genotyping analysis using 165 microsatellite markers located across the genome. We identified eleven genome-wide significant QTL in six chromosomal regions (SSC 2, 7, 8, 13, 14, and 15) and 59 suggestive QTL in 17 chromosomal regions (SSC 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 12, 13, 14, 15, 16, 17, and 18). We also observed significant effects of reciprocal crosses on some of the traits, which would seem to result from maternal effect, QTL on sex chromosomes, imprinted genes, or genetic difference in mitochondrial DNA. The role of genomic imprinting in clinical-chemical traits also was investigated. Genome-wide analysis revealed a significant evidence for an imprinted QTL in SSC4 affecting serum amylase levels. Additionally, a series of bivariate linkage analysis provided strong evidence that QTL in SSC 2, 13, 15, and 18 have a pleiotropic effect on clinical-chemical traits. In conclusion, our study detected both novel and previously reported QTL influencing clinical-chemical traits in pigs. The identified QTL together with the positional candidate genes identified here could play an important role in elucidating the genetic structure of clinical-chemical phenotype variation in humans and swine.</P>
Multifunctionalized Cantilever Systems for Electronic Nose Applications
Yoo, Yong Kyoung,Chae, Myung-Sic,Kang, Ji Yoon,Kim, Tae Song,Hwang, Kyo Seon,Lee, Jeong Hoon American Chemical Society 2012 ANALYTICAL CHEMISTRY - Vol.84 No.19
<P>Multiple target detection using a cantilever is essential for biosensor, chemical sensor, and electronic nose systems. We report a novel microcantilever array chip that includes four microreaction chambers in a chip, which consequently contains four different functionalized surfaces for multitarget detection. For model tests, we designed microcantilever chips and demonstrated the ability of binding of 2,4-dinitrotoluene (DNT) targets onto four different surfaces. We used peptide receptors that are known to have highly selective binding. By simply using four microreaction chambers, we immobilized DNT specific peptide (HPNFSKYILHQRC; SP), DNT nonspecific peptide (TSMLLMSPKHQAC; NSP), and self-assembled monolayer (SAM) as well as a bare cantilever. After flowing DNT gases through the cantilever chip, we could monitor the four different binding signals simultaneously. The shifts in NSP provided information as a negative control because it contained information of temperature fluctuations and mechanical vibration from gas flow. By utilizing the differential signal of the SP and NSP, we acquired 7.5 Hz in resonant responses that corresponds with 160 part per billion (ppb) DNT concentration, showing the exact binding response by eliminating the inevitable thermal noise, vibration noise, as well as humidity effects on the peptide surface.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancham/2012/ancham.2012.84.issue-19/ac3015615/production/images/medium/ac-2012-015615_0008.gif'></P>
A Novel Method to Measure Superior Migration of the Humeral Head
Kyoung Jin Park,Hyeon Jun Eun,Yong Min Kim,Jun Il Yoo,Chae Ouk Lim 대한견주관절의학회 2016 대한견주관절학회지 Vol.19 No.3
Background: Superior migration of humeral head has been conventionally determined by measuring the acromiohumeral distance (AHD), We sought to devise a novel measurement system more reliably and accurately than AHD. We described a structural landmark called ‘C-line’. In this study, we investigated the clinical usefulness of ‘step-off of the C-line (SOC)’ compared to that of AHD. Methods: The C-line formed from the medial margin of the proximal humeral head continuing up to the inferior margin of the articular glenoid and then to the lateral border of the scapula. The superior migration of the humeral head triggered by a rotator cuff tear introduces a discontinuity in this C-line. We measured the distance of this discontinuity. We enrolled 144 patients who underwent a rotator cuff repair. We selected 58 controls who didn’t have any cuff lesions apparent on magnetic resonance imaging. Using radiographs derived from standardized true anteroposterior views of the shoulder, we measured the SOC and the AHD. We used t-tests for statistical analyses. Results: A rotator cuff tear was associated with an increase in SOC and a decrease in AHD. In control group, the mean SOC was 1.29 ± 1.71 mm and AHD was 9.71 ± 2.65 mm. In cuff tear group, the mean SOC was 3.15 ± 3.41 mm and AHD was 8.28 ± 1.76 mm. The mean SOCs of the patient group in relation to the mean SOC of the control group according to tear size, the SOCs of medium tear and lager groups showed statistically significant increase (p<0.05). Conclusions: The SOC may be a similarly effective to diagnose cuff tears of medium size and larger compared with AHD.
Chae, Myung-Sic,Yoo, Yong Kyoung,Kim, Jinsik,Kim, Tae Geun,Hwang, Kyo Seon Elsevier 2018 Sensors and actuators. B Chemical Vol.272 No.-
<P><B>Abstract</B></P> <P>A reduced graphene oxide-based enzyme-modified field-effect transistor (RGO-EnFET) was fabricated to study the enzymatic kinetics between acetylcholinesterase (AChE) and acetylcholine (ACh), which are related to the progression and treatment of Alzheimer’s disease (AD). The RGO-EnFET exhibited typical ambipolar transfer characteristics with a charge neutrality point (the Dirac point, <I>V<SUB>Dirac</SUB> </I>) in an aqueous environment, and biological events occurring on the RGO surface were evaluated by observing the Dirac point shift (Δ<I>V<SUB>Dirac</SUB> </I>) according to reactions. First, the pH sensitivity of the RGO-EnFET was measured to be 24.12 mV pH<SUP>−1</SUP> for a pH range of 4–10 with excellent repeatability. Then, ACh quantification in the concentration range of 1 μM–10 mM was evaluated, with a linear slope of 13.9 mV dec<SUP>−1</SUP> being obtained between Δ<I>V<SUB>Dirac</SUB> </I> and the ACh concentration on a logarithmic scale. The effects of AChE inhibitors (donepezil and rivastigmine) on the AChE enzymatic activity were also investigated. The distinguishable inhibition rates were acquired for donepezil and rivastigmine at saturation levels of 90% and 75%, respectively. These results indicate that the RGO-EnFET biosensor was successfully exploited as an <I>in vitro</I> analytical tool and has potential of future application in the study of enzymatic kinetics and drug screening for therapeutic purposes.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A reduced graphene oxide-based field-effect transistor (RGO-FET) biosensor is produced. </LI> <LI> The device is used to recognize specific target proteins and sense pH values. </LI> <LI> Enzymatic activities of acetylcholinesterase and the inhibition reactions are assessed. </LI> <LI> The RGO-FET bioensor is a promising <I>in situ</I> analytical tool for studying drug effects on Alzheimer’s disease treatment. </LI> </UL> </P>
Pathogenic genotype of Theileria orientalis associated with cattle anemia in Republic of Korea
Kyoung Seong Choi,Su-hee Kim,Chang Yong Choi,Young Hoon Jung,Gae Gyu Yoo,Jin Hee Kang,Suk Han Jung,Do Hyeon Yu,Hyeon Chul Kim,Bae Keun Park,Joon Seok Chae,Jin-ho Park 대한수의학회 2017 대한수의학회 학술대회발표집 Vol.2017 No.-
편재형 컴퓨팅 환경에서 XHTML과 VoiceXML간 EXI 문서의 변환시스템 설계와 구현
신경희(Kyoung-Hee Shin),곽동규(Dong-Gyu Kwak),유재우(Chae-Woo Yoo) 한국컴퓨터정보학회 2009 韓國컴퓨터情報學會論文誌 Vol.14 No.11
편재형 컴퓨팅 환경은 다양한 컴퓨팅 장비의 접속만큼이나 그 응용분야도 다양하다. 이러한 컴퓨팅환경에서 XML은 최적의 데이터 표현이다. W3C 표준인 XML은 XSLT를 이용하여 다른 응용분야에 적절한 데이터 변환이 가능하다. 그러나 XML은 텍스트 기반으로 이진데이터 저장방식에 비해 파일의 크기가 커서 컴퓨팅 파워가 적은 편재형 컴퓨팅 환경에서는 다루기가 어렵다는 단점을 갖고 있다. 본 논문에서는 XML문서의 인코딩 방법에 대하여 살펴보고 자원을 적게 사용하는 편재형 컴퓨팅 환경에서 인코딩 된 EXI 포맷의 XML문서가 다른 응용의 적합한 EXI 포맷 XML 문서으로의 변환방법을 제안한다. 다양한 응용환경 중에서 본 논문에서는 EXI 포맷의 XHTML 문서를 EXI 포맷 VoiceXML로 변환하는 시스템을 제시한다. 이 시스템은 자원이 적은 편재형 컴퓨팅 환경에서 EXI 포맷 XML 문서의 재사용성을 높이고 EXI 포맷의 XML활용에 기여할 수 있다. In a pervasive environment, there are various applications as much as connections of various devices. In this computing environment, XML is the most suitable data representation method. XML is able to transform data for other application areas using XSLT. XML is text-based, the file size of XML document is bigger than binary data file. Therefore, XML has a disadvantage that it is hard to deal with XML in a pervasive environment. In this paper, we survey encoding methods of XML documents, and then we propose a transform method that transforms an encoded EXI format XML document into an EXI format XML document suited for other applications. Among various applications, we present a system that transforms an EXI format XHTML document into an VoiceXML document. This system can improve reusability of EXI format XML documents in a pervasive environment and it is expected to contributes utilization of EXI format XML documents.