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- 저자 : Cao Lu (검색결과 123 건)
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Cao, Chunyan,Xie, Along,Zhou, Tianliang,Zhong, Haichang,Lu, Xiangjun,Xie, An,Noh, Hyeon Mi,Jeong, Jung Hyun Elsevier 2020 Journal of luminescence Vol.217 No.-
<P><B>Abstract</B></P> <P>Some lutetium molybdenum oxides were synthesized through a solid-state reaction method. By adjusting the molar ratios of raw materials of Lu<SUB>2</SUB>O<SUB>3</SUB> (Eu<SUB>2</SUB>O<SUB>3</SUB>) to MoO<SUB>3</SUB>, Eu<SUP>3+</SUP> doped lutetium molybdenum oxides Lu<SUB>2</SUB>MoO<SUB>6</SUB>, Lu<SUB>2</SUB>Mo<SUB>2</SUB>O<SUB>9</SUB>, Lu<SUB>2</SUB>(MoO<SUB>4</SUB>)<SUB>3</SUB>, and Lu<SUB>6</SUB>MoO<SUB>12</SUB> were obtained. The materials were characterized by X-ray diffraction (XRD) patterns, scanning electron microscope (SEM) images, energy-dispersive spectra (EDS), diffuse reflection (DR) spectra, photoluminescence (PL) excitation and emission spectra, luminescence decay curves, and temperature dependent integrated emission spectra. Enhanced excitation and emission spectra were recorded at high temperatures. Possible energy transfer processes were proposed to explain the excitation and emission spectra. By combining some phosphors with near ultraviolet (NUV) chips, the obtained light emitting diodes (LEDs) gave red light under forward bias current. The results suggest that the obtained Eu<SUP>3+</SUP> doped lutetium molybdenum oxides have potential applications in phosphor converted based NUV LEDs.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Eu<SUP>3+</SUP> doped Lu<SUB>2</SUB>MoO<SUB>6</SUB>, Lu<SUB>2</SUB>Mo<SUB>2</SUB>O<SUB>9</SUB>, Lu<SUB>2</SUB>(MoO<SUB>4</SUB>)<SUB>3</SUB>, and Lu<SUB>6</SUB>MoO<SUB>12</SUB> were obtained. </LI> <LI> The materials present different structures, morphologies, optical properties, and luminescece decay behaviors. </LI> <LI> Eu<SUP>3+</SUP> concentration dependent optical properties in Lu<SUB>2</SUB>MoO<SUB>6</SUB> were researched. </LI> <LI> Enhanced excitation and emission spectra were recorded under high temperatures in some materials. </LI> <LI> Red LEDs were obtained by packaging phosphors to NUV LED chips. </LI> </UL> </P>
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Lu Yunjun,Li Shu,Shen Xiaodong,Zhao Yan,Zhou Dongming,Hu Dan,Cai Xushen,Lu Lixia,Xiong Xiaohui,Li Ming,Cao Min 한국미생물학회 2021 The journal of microbiology Vol.59 No.10
Streptococcus suis serotype 2 (S. suis 2) is an important zoonotic pathogen that presents a significant threat both to pigs and to workers in the pork industry. The initial steps of S. suis 2 pathogenesis are unclear. In this study, we found that the type II histidine triad protein HtpsC from the highly virulent Chinese isolate 05ZYH33 is structurally similar to internalin A (InlA) from Listeria monocytogenes, which plays an important role in mediating listerial invasion of epithelial cells. To determine if HtpsC and InlA function similarly, an isogenic htpsC mutant (ΔhtpsC) was generated in S. suis by homologous recombination. The htpsC deletion strain exhibited a diminished ability to adhere to and invade epithelial cells from different sources. Double immunofluorescence microscopy also revealed reduced survival of the ΔhtpsC mutant after cocultivation with epithelium. Adhesion to epithelium and invasion by the wild type strain was inhibited by a monoclonal antibody against E-cadherin. In contrast, the htpsC-deficient mutant was unaffected by the same treatment, suggesting that E-cadherin is the host-cell receptor that interacts with HtpsC and facilitates bacterial internalization. Based on these results, we propose that HtpsC is involved in the process by which S. suis 2 penetrates host epithelial cells, and that this protein is an important virulence factor associated with cell adhesion and invasion.
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Lu-Hao Cao,Xi-Yuan Wu K기업경영연구원 2023 KBM Journal(K Business Management Journal) Vol.7 No.2
By the end of 2022, the number of WeChat 5.0 users has reached more than 1000 million, 800 million of whom stay active, and WeChat public platform also had acquired 2 million public accounts. Among the numerous WeChat official accounts, the official accounts of colleges and universities have always been the focus of media attention. With the development of We Media, the presentation mode of WeChat official account has changed from simple information transmission mode to various other modes, and the information presentation mode has become more diversified. By studying the characteristics of content on university WeChat official accounts and reference items for audience reactions such as likes, this study aims to explore the relationship between audience reactions on WeChat official accounts, effectively understand the factors influencing the reading volume of university WeChat official accounts, and explore the communication strategies of WeChat public accounts. This paper uses the content analysis method to rank the number of weekly push articles read by Qingbo's big data on college WeChat public accounts from 2016 to 2017. These ranked articles are selected as samples, and random sampling is conducted from these samples. A total of 1200 valid samples will be analyzed to draw conclusions: The higher the popularity, the more likes and reading volume; The correlation between the originality of the posted article and the reading volume is not strong. I hope this paper can provide some reference meaning for the development of the Wechat official accounts.
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Huber Second-order Variable Structure Predictive Filter for Satellites Attitude Estimation
Lu Cao,Dechao Ran,Xiaoqian Chen,Xianbin Li,Bing Xiao 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.7
This work presents a novel filtering approach to the high-accuracy attitude estimation problem of satellites. A new second-order variable structure predictive filter is first designed with the measurement errors and theirdifference reduced. The key feature of this filter is that the noise handled is not constrained to be the Gaussianwhite noise. Hence, it is a new solution to filtering problem in the presence of modeling errors or heavy-tailednoise. Then, the robust version of the preceding filter is developed by using the Huber technique. This robustfilter can ensure great robustness and perfect estimation accuracy/precision for the satellite attitude. The Lyapunovstability analysis proves that the measurement error and its difference can be stabilized into a small set with a fasterrate of convergence. The effectiveness of the presented attitude estimation filters is validated via simulation bycomparing with the traditional cubature Kalman filter.
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Effects of Florfenicol and Chromium (III) on Humoral Immune Response in Chicks
Cao, Jiyue,Li, Kui,Lu, Xiaocong,Zhao, Yaxin Asian Australasian Association of Animal Productio 2004 Animal Bioscience Vol.17 No.3
One hundred and sixty day-old Hainan chicks were randomly allotted into eight pens to investigate the effect of different dietary concentrations of chromium (Cr) in the form of chromium chloride, and different dosages of florfenicol on humoral immune responses by determining antibody titers to Newcastle disease (ND) vaccines using the hemagglutination inhibition test. The results indicated that ND antibody titers were significantly higher in chicks receiving Cr at low (5 mg/kg feed) and middle (10 mg/kg feed) dose compared with the control (p<0.01). However, ND antibody titers were significantly decreased in chicks receiving Cr at a high dosage of 500 mg/kg feed (p<0.01), though the ND antibody titers of the early days (d 21 and d 28 of age) were higher than that of the control group. It is suggested that excessive Cr intake has detrimental effects on ND antibody production in chicks. No significantly lower response was measured in chicks that received florfenicol at a low dosage of 50 mg/kg feed (p>0.05), but the ND antibody titers were significantly decreased in chicks receiving 200 and 400 mg/kg feed of the drug (p<0.01). The ND antibody titers of group receiving 200 mg/kg feed of florfenicol plus 10 mg/kg Cr were slightly higher than that of the group receiving single florfenicol of 200 mg/kg although, no significant differences were observed between these two treatments. It is suggested that the humoral immune response impaired by florfenicol (200 mg/kg feed) could not be significantly reversed by Cr (10 mg/kg feed).
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Lu, Feng,Ahmed, Md Atique,Xu, Simin,Xu, Sui,Han, Jin-Hee,Liu, Qianyan,Chen, Jing,Zhu, Guoding,Zhou, Huayun,Cao, Jun,Han, Eun-Taek ELSEVIER 2019 INFECTION GENETICS AND EVOLUTION Vol.70 No.-
<P><B>Abstract</B></P> <P>Imported malaria due to <I>Plasmodium ovale curtisi</I> and <I>P</I>. <I>ovale wallikeri</I> infections from African countries has increased recently (2011–2014) in Chinese travelers. We report novel genotypes, their prevalence and the predominant haplotypes of <I>P</I>. <I>ovale curtisi</I> and <I>P</I>. <I>ovale wallikeri</I> circumsporozoite protein (CSP) from 20 African countries in Chinese travelers. These genotypes should be considered while designing a CSP-based vaccine against <I>P</I>. <I>ovale</I> malaria.</P> <P><B>Highlights</B></P> <P> <UL> <LI> This is the first to report the <I>csp</I> genotypes and their heterogeneity for <I>P. ovale curtisi</I> and <I>P. ovale wallikeri</I> parasites from African countries. </LI> <LI> Ten <I>csp</I> genotypes of <I>P</I>. <I>ovale curtisi</I> and 13 <I>csp</I> genotypes of <I>P</I>. <I>ovale wallikeri</I> based on the arrangement of central repeat motifs were found. </LI> <LI> Fifteen <I>csp</I> haplotypes of <I>P</I>. <I>ovale curtisi</I> and 10 <I>csp</I> haplotypes of <I>P</I>. <I>ovale wallikeri</I> on central repeat motifs were identified. </LI> <LI> These genotypes should be considered while designing a CSP-based vaccine against <I>P</I>. <I>ovale</I> malaria. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
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Cao, Yin,Yang, Yingbo,Wu, Hui,Lu, Yi,Wu, Shuang,Liu, Lulu,Wang, Changhong,Huang, Fei,Shi, Hailian,Zhang, Beibei,Wu, Xiaojun,Wang, Zhengtao The Korean Society of Ginseng 2020 Journal of Ginseng Research Vol.44 No.3
Backgroud: Sleep deprivation (SD) impairs learning and memory by inhibiting hippocampal functioning at molecular and cellular levels. Abnormal autophagy and apoptosis are closely associated with neurodegeneration in the central nervous system. This study is aimed to explore the alleviative effect and the underlying molecular mechanism of stem-leaf saponins of Panax notoginseng (SLSP) on the abnormal neuronal autophagy and apoptosis in hippocampus of mice with impaired learning and memory induced by SD. Methods: Mouse spatial learning and memory were assessed by Morris water maze test. Neuronal morphological changes were observed by Nissl staining. Autophagosome formation was examined by transmission electron microscopy, immunofluorescent staining, acridine orange staining, and transient transfection of the tf-LC3 plasmid. Apoptotic event was analyzed by flow cytometry after PI/annexin V staining. The expression or activation of autophagy and apoptosis-related proteins were detected by Western blotting assay. Results: SLSP was shown to improve the spatial learning and memory of mice after SD for 48 h, accomanied with restrained excessive autophage and apoptosis, whereas enhanced activation of phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin signaling pathway in hippocampal neurons. Meanwhile, it improved the aberrant autophagy and apoptosis induced by rapamycin and re-activated phosphoinositide 3-kinase/Akt/mammalian target of rapamycin signaling transduction in HT-22 cells, a hippocampal neuronal cell line. Conclusion: SLSP could alleviate cognitive impairment induced by SD, which was achieved probably through suppressing the abnormal autophagy and apoptosis of hippocampal neurons. The findings may contribute to the clinical application of SLSP in the prevention or therapy of neurological disorders associated with SD.
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