RISS 학술연구정보서비스

검색
다국어 입력

http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.

변환된 중국어를 복사하여 사용하시면 됩니다.

예시)
  • 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
  • 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
닫기
    인기검색어 순위 펼치기

    RISS 인기검색어

      검색결과 좁혀 보기

      선택해제
      • 좁혀본 항목 보기순서

        • 원문유무
        • 원문제공처
          펼치기
        • 등재정보
          펼치기
        • 학술지명
          펼치기
        • 주제분류
          펼치기
        • 발행연도
          펼치기
        • 작성언어

      오늘 본 자료

      • 오늘 본 자료가 없습니다.
      더보기
      • 무료
      • 기관 내 무료
      • 유료
      • KCI등재

        [논문]보육교사의 보육컨설팅에 대한 인식, 요구도 및 활성화 방안

        황해익,조준오,김병만 부산대학교 교육연구소 2012 교육혁신연구 Vol.22 No.1

        The purpose of this study was to examine the awareness of childcare teachers on childcare consulting, their needs for that and ways of revitalizing childcare consulting in a bid to lend professional assistance to childcare centers in terms of how to boost the quality of childcare. And it's also meant to provide some information on how to improve childcare consulting both in theory and practice. The subjects in this study were 200 childcare teachers in the city of Busan. The findings of the study were as follows: First, as a result of analyzing their awareness of childcare consulting, 147 respondents (87.5%) considered that to be necessary or very necessary. As for the reason for the necessity of childcare consulting, the biggest group that numbered 62 responded (42.2%) that it would be necessary to pinpoint and resolve problems. Concerning the reason why it's not necessary, the largest group that numbered four answered (19.1%) that there was no problem about which childcare consulting would be required. Second, as a result of checking their needs for childcare consulting, the biggest group that numbered 35 asked (20.8%) for education about accreditation indicators in terms of the content of childcare consulting. Regarding childcare consultants, the biggest group that numbered 55 preferred (32.7%) professional assistants, lecturers and professional personnels of childcare centers. Concerning the term of childcare consulting, the largest group that numbered 71 considered (42.3%) it advisable to receive this consulting for less than a week. As to the time for childcare consulting, the biggest group that numbered 58 answered (34.5%) that it should be provided at the request of accredited childcare centers. Third, as a result of analyzing their opinions on how to revitalize childcare consulting, the biggest group that numbered 128 felt (76.2%) the need for a separate consulting institution. The largest group that numbered 30 thought (23.4%) that the Ministry of Health and Welfare should be responsible for that, and the greatest group that numbered 76 thought (45.2%) that the top priority for childcare consulting would be to secure professional childcare consultants. 본 연구는 보육교사의 보육컨설팅에 대한 인식과 요구도 및 활성화 방안을 확인하여 어린이집의 개별적인 질적 수준 관리 및 지속적인 질 향상에 전문적이고 체계적인 도움을 제공하고, 향후 보육컨설팅의 개념적․실제적 측면을 보완하는 데 기초자료로 활용하는 것에 연구의 목적이 있다. 본 연구는 부산광역시에서 근무하는 보육교사 200명을 연구대상으로 선정하였고, 회수된 설문지 중 총 168부를 최종 분석대상으로 선정하였다. 연구결과를 살펴보면 첫째, 보육컨설팅에 대한 인식을 살펴본 결과 보육컨설팅이 ‘필요하다’와 ‘매우 필요하다’가 총 147명(87.5%)으로 높게 나타났고, 필요한 이유로는 ‘문제진단 및 현안해결’이 62명(42.2%), 불필요한 이유는 ‘보육컨설팅을 필요로 하는 문제가 없기 때문에’가 4명(19.1%)으로 가장 높게 나타났다. 둘째, 보육컨설팅에 대한 요구도를 살펴본 결과 보육컨설팅 내용에 서는 ‘평가인증 지표 교육’이 35명(20.8%), 대상은 ‘조력전문가, 강의, 센터전문요원’이 55명(32.7%), 보육 컨설팅 실시기간은 ‘1주일 미만’이 71명(42.3%), 보육컨설팅 실시 시기는 ‘평가인증을 통과한 어린이집의 요청 시’가 58명(34.5%), 보육컨설팅 지도방법은 ‘원장, 교사 상호작용 및 의견 교환’이 69명(41.1%)으로 가장 높게 나타났다. 셋째, 보육컨설팅에 대한 활성화 방안을 살펴본 결과 전담기관의 필요성은 ‘필요하다’가 128명(76.2%), 전담부서는 ‘보건복지부’가 30명(23.4%), 보육컨설팅 활성화를 위해 가장 필요한 과제는 ‘전문성을 갖춘 보육컨설턴트의 확보’가 76명(45.2%)으로 가장 높게 나타났다. 끝으로 본 연구에 서는 보육교사의 보육컨설팅에 대한 인식과 요구도 그리고 활성화 방안을 토대로 중요성과 필요성을 논의하였다.

      • 공항특수경비원의 고객불평행동과 서비스회복 및 고객만족에 대한 차이검증

        조병해 ( Jo Byung-hae ) 한국안전문화연구원 2018 현대사회와 안전문화 Vol.1 No.1

        연구목적: 본 연구는 공항특수경비조직의 고객불평행동과 서비스회복 및 고객만족에 대한 차이검증을 규명하는데 있다. 연구방법: 본 연구의 목적을 달성하기 위하여 2013년 5월 10일부터 7월 10일 까지 인천소재 공항시설을 이용하는 일반인들을 모집단으로 선정한 다음 집락무선표집법을 이용 500명을 표집 하였다. 불성실한 자료를 제외하고 최종분석에 사용된 사례 수는 434명이다. 수집된 자료는 SPSSWIN 18.0을 이용하여 연구의 목적에 따라 분석 하였으며, 통계기법은 요인분석, 신뢰도분석, 독립표본 t 검증, 일원변량분석 등의 방법이 활용되었다. 결론: 결론은 다음과 같다. 첫째, 사회인구학적특성에 따라서 고객불평행동, 서비스회복, 고객만족은 차이가 있다. 고객불평행동의 경우 성별에 따른 보상추구는 여성, 연령과 학력에 따른 공적행동과 보상추구는 20대 연령층과 대학원이상의 집단, 직업에 따른 공적행동, 보상추구, 사적행동은 학생, 공항이용횟수에 따른 공적행동과 사적행동은 6회이상 이용 집단, 보상추구는 2-5회 이용집단, 그리고 월수입에 따른 공적행동은 500만원 이상의 집단에서 높다. 둘째, 서비스회복의 경우 성별에 따른 절차공정성은 여성, 연령에 따른 절차공정성과 분배공정성은 20 대 연령층에서 높다. 셋째, 고객만족의 경우 학력에 따른 이용결정만족은 대학원 이상 집단, 공항이용횟수에 따른 서비스구성만족은 1회 이용한 경험 집단에서 높다. Purpose: This study aims at exploring the relation of airport special guard’s customer complaint action, service recovery and customer’s satisfaction. Methods: To attain the purpose of this study, this study selected the general public using the airport facilities in Incheon as population from May 10 to Jul. 10, 2013 and collected 500 people using cluster random sampling. Excluding unhonest data, the number of cases used for the final analysis was 434 people. The collected data were analyzed for the study purpose using SPSSWIN 18.0, as statistical techniques, factor analysis, reliability analysis, correlation analysis, t-test, one-way ANOVA, multiple regression analysis, path analysis etc. were used. Conclusion: The findings are as follows. First, there is difference in customer complaint action, service recovery and customer’s satisfaction according to socio-demographical features.

      • 공항시설 이용고객의 고객불평행동과 고객만족 요인분석: : 특수경비원들을 중심으로

        조병해 ( Byung Hae Jo ),김찬선 ( Chan Sun Kim ) 한국시큐리티융합경영학회 2014 한국융합과학회지 Vol.3 No.2

        Pupose: This study aims at analyzing factors of airport facilities users’ customer complaints action and satisfaction. Methods: General citizens using Incheon International Airport facilities in 2013 were selected as a population and the number of cases used for final analysis using cluster random sampling is total 434 people. The questionnaire used for the study was composed of total 26 items and using SPSSWIN 18.0, factor analysis, reliability analysis, independent sample t-test, one-way ANOVA. The reliability of the questionnaire sheet was indicated to be over αα=.798. =.The findings are as follows. Conclusion: First, there is difference in customers’ complaints according socio-demographical features. For pursuit of compensation by sex in case of customers’ complaint action, public action and pursuit of compensation by female, aga ena dschool background is high in the age class of their 20s and the group of over graduate school and public action, pursuit of compensation and private action by job is high in students’ group, public action and private action by airport use times is high in the group using over 6 times, pursuit for compensation is high in the group using 2 or 5 times and public action by monthly income is high in the group of over 5.0 million won. Second, in case of customers’ satisfaction, satisfaction with use decision by school background is high in the group of over graduate school, satisfaction with service composition by airport use times is high in the group experiencing one time use. TThird, hird, customers’ complaint action has an effect on satisfaction with use decision. That is, the more pursuit action for compensation is shown, the more satisfaction with use decision is increased, while the more private action is shown, the lower satisfaction with use decision is shown. Fourth, customers’ complaint action has an effect on satisfaction with service composition. That is, the more compensation pursuit action is shown, the more satisfaction with service composition is increased, while the more private action is shown, the lower satisfaction with service composition is shown.

      • 단열혼합반응기에서 연속반응에 관한 이론적 해석

        조병욱,김선일,홍완해,차월석,김숭평,김정규 조선대학교 원자력연구소 1990 原子力硏究 Vol.4 No.-

        By mathematical model for the case of the consecutive first-order exothermic reaction in an adiabatic CSTR, the effects of the system parameter i. e. relative residence time, heat of reaction and thermal sensitivity of reaction rate constant, on the concentration profile of the intermediate product of a consecutive reaction were obtained as follows For fixed values of the ratio of the reaction rate constants t_1/t_2, the ratioof the corresponding system parameters α where α>and the sensitivities of the reaction rate constants S1 and S2, the maximum value of the intermediate production dimensionless concentration increases with increase in the values of the relative energy parameter E1 and E2 and it decreases with a decrease in E1 and E2. For fixed values of the ratio of the reaction rete constants t_1/t_2, the ratio of the corresponding system parameter α where α<and the relative energy parameters E1 and E2, the maximum value of the intermediate product dimensionless concentration decreases with an increase in the sensitivities of the reaction rate constants t_1 and t_2 and it increases with a decrease in S1 and S2. For fixed values of the ratio of the reaction rate constants t_1/t_2, tile ratio of the corresponding system parameters α where α= 1 and the relative energy parameters E1 and E2, the maximum value of the intermediate product dimensionless is constant with either increase or decrease in the sensitivities of the reaction rate constants S1 and S2.

      • KCI등재

        A Natural L-Arginine Analog, L-Canavanine-Induced Apoptosis is Suppressedby Protein Tyrosine Kinase p56<SUP>lck</SUP> in Human Acute Leukemia Jurkat T Cells

        Hae Sun Park(박해선),Do Youn Jun(전도연),Hyun Ju Woo(우현주),Seok Woo Rue(류석우),Sang Kook Kim(김경민),Kyung Min Kim(김상국),Wan Park(박완),Byung Jo Moon(문병조),Young Ho Kim(김영호) 한국생명과학회 2009 생명과학회지 Vol.19 No.11

        L-arginine 구조유사체인 L-canavanine의 인체 급성백혈병 Jurkat T 세포에 대한 apoptosis 유도활성이 단백질 티로신키나아제 p56<SUP>lck</SUP>에 어떻게 조절되는지를 규명하기 위해 p56<SUP>lck</SUP>를 발현하는 Jurkat T 세포주 E6.1과 p56<SUP>lck</SUP>-결손 Jurkat T 세포주 JCaM1.6에 있어서 L-canavanine의 세포독성, L-canavanine에 의해 유도되는 apoptotic DNA fragmentation 및 apoptotic sub-G1 peak를 비교하여 본 바, p56<SUP>lck</SUP>-negative JCaM1.6 세포가 p56<SUP>lck</SUP>-positive E6.1 세포에 비해 L-canavanine의 apoptotis 유도활성에 훨씬 더 민감한 것으로 나타났다. 이러한 p56lck-negative JCaM1.6 세포의 민감성은 JCaM1.6 세포에 p56<SUP>lck</SUP> 유전자를 transfection시켜 발현시키면 현저히 감소되었다. L-Canavanine에 의해 유도되는 apoptosis관련 현상들을 p56<SUP>lck</SUP>-stable transfectant인 JCaM1.6/lck 세포와 empty vector-transfectant 인 p56<SUP>lck</SUP>-negaive JCaM1.6/vector 세포에서 Western blot analysis로 비교한 결과, L-canavanine에 의해 유도되는 mitochondrial membrane potential (Δψm)의 감소, caspase-9, -8, -7 및 -3의 활성화, 그리고 PARP 및 PLCγ-1의 분해가 JCaM1.6/vector 세포에 비해 JCaM1.6/lck 세포에서 더 약하게 나타났다. JCaM1.6/lck 세포를 2.5 mM L-canavanine으로 처리한 다음 세포 내 p56<SUP>lck</SUP> kinase 활성의 변화를 α-casein을 기질로 하여 시간 별로 측정한 결과, L-canavanine의 처리 후 15분만에 p56<SUP>lck</SUP> kinase의 활성이 약 1.6배 증가되었으며 이후 6시간 동안은 약 1.3~1.4 배정도 증가된 수준으로 kinase 활성이 유지되는 것으로 확인되었다. L-Canavanine에 의한 apoptosis의 개시에 Fas/FasL 상호작용이 관련되는지를 규명하기 위해 FADD-negative Jurkat T 세포주 I2.1, caspase-8-negative Jurkat T 세포주 I9.2 및 wild-type Jurkat T 세포주 A3에 대한 L-canavanine의 세포독성을 비교한 결과, A3와 I2.1 세포의 경우는 L-canavanine의 세포독성이 동일하게 나타났고, 특히 caspase-8가 결손된 I9.2 세포의 경우는 L-canavanine의 세포독성에 대한 민감성이 A3와 I2.1 세포에 비해 단지 미약하게만 완화되는 것으로 나타나, L-canavanine의한 apoptosis에는 Fas/FasL 상호작용이 관련되어 있지 않으며, 또한 caspase-8의 역할이 필수적이지 않음을 시사하였다. Jurkat T 세포에 있어서 L-canavanie에 의해 유도되는 sub-G1 peak 및 caspases 활성화에 미치는 pan-caspase inhibitor (z-VAD-fmk), caspase-9 inhibitor (z-LEHD-fmk), caspase-3 inhibitor (z-DEVD-fmk), caspase-4 inhibitor (z-LEVD-fmk) 및 caspase-12 inhibitor (z-ATAD-fmk)의 영향을 조사한 결과, L-canavanie에 의한 apoptosis는 Δψm의 감소, caspase-9 및 caspase -3의 활성화에 뒤따른 caspase-8 및 caspase-7의 활성화, 그리고 PARP의 분해의 순서로 유도되는 것으로 나타났으며, 아울러 caspase-9의 활성화와 함께 caspase-12의 활성화가 L-canavanine 처리에 따른 caspase-3의 활성화에 요구되는 것으로 확인되었다. 결론적으로, L-canavanine 처리에 의한 Jurkat T 세포의 apoptosis는 Δψm 감소, caspase-9, caspase-3 및 caspase-7의 활성화에 의해 유도되며, 이들 apoptosis 현상들은 p56<SUP>lck</SUP>에 의해 negative regulation되었다. To elucidate further the antitumor effects of a natural L-arginine analogue, L-canavanine, the mechanism underlying apoptogenic activity of L-canavanine and its modulation by protein tyrosine kinase p56<SUP>lck</SUP> was investigated in human Jurkat T cells. When the cells were treated with 1.25 to 2.5 mM L-canavanine for 36 h, several apoptotic events including mitochondrial membrane potential (Δψm) loss, activation of caspase-9, -3, -8, and -7, poly (ADP-ribose) polymerase (PARP) degradation, and DNA fragmentation were induced without alteration in the levels of Fas or FasL. These apoptotic changes were more significant in p56<SUP>lck</SUP>-deficient Jurkat clone JCaM1.6 than in p56<SUP>lck</SUP>-positive Jurkat clone E6.1. The L-canavanine-induced apoptosis observed in p56<SUP>lck</SUP>-deficient JCaM1.6 cells was significantly reduced by introducing p56<SUP>lck</SUP> gene into JCaM1.6 cells by stable transfection. Treatment of JCaM1.6/lck cells with L-canavanine caused a transient 1.6-fold increase in the kinase activity of p56<SUP>lck</SUP>. Both FADD-positive wild-type Jurkat T cell clone A3 and FADD-deficient Jurkat T cell clone I2.1 exhibited a similar susceptibility to the cytotoxicity of L-canavanine, excluding involvement of Fas/FasL system in triggering L-canavanine-induced apoptosis. The L-canavanine-induced apoptotic sub-G1 peak and activation of caspase-3, -8, and -7 were abrogated by pan-caspase inhibitor (z-VADfmk), whereas L-canavanine-induced activation of caspase-9 was not affected. These results demonstrated that L-canavanine caused apoptosis of Jurkat T cells via the loss of Δψm, and the activation of caspase-9, -3, -8, and -7, leading to PARP degradation, and that the p56<SUP>lck</SUP> kinase attenuated the Δψm loss and activation of caspases, and thus contributed as a negative regulator to L-canavanine-induced apoptosis.

      • 3D Printer-Based Encapsulated Origami Electronics for Extreme System Stretchability and High Areal Coverage

        Jo, Mansik,Bae, Seunghwan,Oh, Injong,Jeong, Ji-hun,Kang, Byungsoo,Hwang, Seok Joon,Lee, Seung S.,Son, Hae Jung,Moon, Byung-Moo,Ko, Min Jae,Lee, Phillip American Chemical Society 2019 ACS NANO Vol.13 No.11

        <P>Stretchability and areal coverage of active devices are critical design considerations of stretchable or wearable photovoltaics and photodetections where high areal coverages are required. However, simultaneously maximizing both properties in conventional island-bridge structures through traditional two-dimensional manufacturing processes is difficult due to their inherent trade-offs. Here, a 3D printer-based strategy to achieve extreme system stretchability and high areal coverage through combining fused deposition modeling (FDM) and flexible conductive nanocomposites is reported. Distinguished from typical approaches of using conductive filaments for FDM which have a flexibility dilemma and conductivity trade-offs, the proposed axiomatic approach to embed a two-dimensional silver nanowire percolation network into the surfaces of flexible 3D printed structures offers sufficient conductivity and deformability as well as additional benefits of electrical junction enhancement and encapsulation of silver nanowires. Kirigami/origami-pattern-guided three-dimensional arrangements of encapsulated interconnections provide efficient control over stretchability and areal coverage. The suggested process enables a perovskite solar module with an initial areal coverage of ∼97% to be electrically and mechanically reversible with 400% system stretchability and 25 000% interconnect stretchability under the 1000 cycle test, by folding down or hiding the origami-applied interconnects under the islands. This 3D printing strategy of potentially low cost, large size capabilities, and high speed is promising for highly flexible future energy conversion applications.</P> [FIG OMISSION]</BR>

      • SCOPUSSCIEKCI등재

        Current Status of Neurosurgical and Neurointensive Care Units in Korea : A Brief Report on Nationwide Survey Results

        Jo, Kwang Wook,Kim, Hoon,Yoo, Do Sung,Hyun, Dong-Keun,Cheong, Jin Hwan,Park, Hae-Kwan,Park, Bong Jin,Cho, Byung Moon,Kim, Young Woo,Kim, Tae Hee,Han, Insoo,Lee, Sang-Weon,Kwon, Taek Hyun The Korean Neurosurgical Society 2020 Journal of Korean neurosurgical society Vol.63 No.4

        Objective : The purpose of this study is identify the operation status of the neurosurgical care units (NCUs) in neurosurgical residency training hospitals nationwide and determine needed changes by comparing findings with those obtained from the Korean Neurosurgical Society (KNS) and Korean Society of Neurointensive Care Medicine (KNIC) survey of 2010. Method : This survey was conducted over 1 year in 86 neurosurgical residency training hospitals and two neurosurgery specialist hospitals and focused on the following areas : 1) the current status of the infrastructure and operating systems of NCUs in Korea, 2) barriers to installing neurointensivist team systems, 3) future roles of the KNS and KNIC, and 4) a handbook for physicians and practitioners in NCUs. We compared and analyzed the results of this survey with those from a KNIC survey of 2010. Results : Seventy seven hospitals (87.5%) participated in the survey. Nineteen hospitals (24.7%) employed a neurointensivist or faculty member; Thirty seven hospitals (48.1%) reported high demand for neurointensivists, and 62 hospitals (80.5%) stated that the mandatory deployment of a neurointensivist improved the quality of patient care. Forty four hospitals (57.1%) believed that hiring neurointensivist would increase hospital costs, and in response to a question on potential earnings declines. In terms of potential solutions to these problems, 70 respondents (90.9%) maintained that additional fees were necessary for neurointensivists' work, and 64 (83.1%) answered that direct support was needed of the personnel expenses for neurointensivists. Conclusion : We hope the results of this survey will guide successful implementation of neurointensivist systems across Korea.

      • KCI등재

        장관 손상으로 확진된 범발성 복막염에 대한 임상적 고찰

        조해창,전성윤,배병조,유동걸,손영길,이정안 대한외상학회 2001 大韓外傷學會誌 Vol.14 No.1

        Background: Generalized peritonitis in abdominal trauma patients is a common disease entity. An injury of the hollow viscera is the major cause of traumatic generalized peritonitis, so it is necessary to study clinical analysis of traumatic generalized peritonitis caused by hollow visceral injury. The aim of this study is to help early diagnosis and appropriate treatment by evaluating patients with traumatic generalized peritonitis. Materials and Methods: We evaluated 76 patients with generalized peritonitis caused by hollow visceral injury after abdominal trauma who had undergone a laparotomy in the Department of General Surgery, Daegu Fatima hospital, from January 1996 to December 2000. The authors reviewed their medical and operation records retrospectively. Results: The results are as follows: 1) The most common ages were in the 3rd, 4th, 5th, and 6th decades (82.9%). There were 59 males and 17 females (M : F=3.5 : 1). 2) the generalized peritonitis caused by hollow visceral injury after abdominal trauma was due to blunt trauma in 45 (59.2%) patients and penetrating trauma in 16 (21.1%) patients. The most common injured organ was the small bowel (53 patients, 69.7%). 3) The most common symptom and sign were abdominal pain (89.4%) and abdominal tenderness (93.4%), followed by rebound tenderness, abdominal distension, and wound pain. 4) There was a leukocytosis in 54 (71.1%) patients. 5) Abdominal CT (72.3%) and simple abdomen (65.8%) was performed for appropriate diagnosis. 6) Sixty-three (63) patients (82.9%) were operated on within 12 hours from injury. 7) The incidence of blood transfusion was more common in penetrating trauma (56.3%). 8) GIT perforation alone occurred in 34 (44.7%) patients. 9) Except for the hollow visceral organ, the most common associated intraabdominal injured organ and extraabdominal injured organ were the mesentery and the pelvis, respectively. 10) The primary repair in 48 (63.2%) patients more commonly involved hollow visceral injury. 11) The most common complications were infection and retension abscess which in 4 (5.3%) patients each. 12) The mortality rate was 3 (3.9%) patients, and the cause of injury in those case, was blunt trauma. Conclusion: We suggest that early diagnosis and speedy transfer are needed in traumatic generalized peritonitis patients. According to the surgical indication, operative treatment should occur as soon as possible to reduce morbidity and mortality in such patients.

      • 흰쥐 십이지장의 점액질에 미치는 Ricin 독성에 대한 조직화학적 연구

        조운복,최병태,강진,조기진,김재호,장혜영 부산대학교 유전공학연구소 1996 분자생물학 연구보 Vol.12 No.-

        피마자 (Ricinus communis) 씨에서 추출한 ricin 75㎍/Kg을 복강내 투여했을 때 십이지장샘과 술잔세포에 미치는 독성을 조직화학적으로 조사하였다. 대조군에서 십이지장샘은 중성점액실만 함유하였으나 십이지장의 술잔세포는 중성점액실과 산성점액질의 혼합성이였다. 술잔세포의 산성점액질 성상은 대부분이 sulfomucin과 sialomucin의 혼합성이나 sulfomucin 또는 sialomucin만을 가진 술잔세포도 관찰되었다. 십이지장샘내에서 대조군과 ricin 투여군사이의 형태적 및 점액질성상 변화는 관찰 할 수 없었으나 융모와 장샘에서는 현저한 변화가 있었다. Ricin 투여후 24시간부터 술잔세포 중에는 커진 세포, 공포 변성된 세포, 세포막이 파괴된 세포 및 미성쑥세포 등이 마타났다. Ricin 투여후 술잔세포수는 융모에서 6시간군부터 감소하다 48시간군부터 다소 증가하였으며, 장샘에서 24시간군부터 감소하다가 120시간군부터 다소 증가하였다. Ricin 투여 후 산성점액질의 감소가 현저하였으며 특히 sulfomucin만을 분비하는 술잔세포가 감소한데 비해 sialomucin 만을 분비하는 세포는 다소 증가하였다. The toxicity of purified ricin from Ricinus communis to duodenal mucosubstances of rat was examined by histochemical method. Sprague-Dawley rats were injected intraperitoneally with 75㎍/Kg body weight of ricin, and were sacrified at intervals of 6, 24, 48 and 120 hours after injection. In the control groups, the duodenal gland contained only neutral mucosubstances, but a mixture of neutral and acidic ones was detected in the goblet cells of duodunum. About the properties of acidic mucosubstances of the goblet cells, the cells containing both sulfomucin and sialomucin were observed in most cells, but two types of cell, one producing sulfomucin and the other producing sialomucin, were also found. In the ricin injected group, the morphology and properties of mucosubstances in the duodenal gland remained the same as the control groups. However, the morphological changes in the villi and intestinal glands including enlarged, vacuolated, demolished and immature goblet cells were observed from 24 hours after injection. And a slight decrease fo goblet cells in total number was noted from 6 and 24 hours after injection in villi and crypts respectively, but reincreased from 48 hours after injection in villi and from 120 hours in crypts. With these changes, the amount of the acidic mucosubstances was significantly decreased in the goblet cells. Especially, the goblet cells secreting sulfomucin decreased in number, while those cells secreting sialomucin increased.

      • 제6차 교육과정에 의한 중학교 과학교과서 중 생물영역에 대한 내용분석

        조운복,박원혁,최병태,조기진,이지은,김혜란 부산대학교 사범대학 과학교육연구소 1995 科學敎育硏究報 Vol.22 No.-

        This study was undertaken to obtain data for developing an ideal middle school biology curriculum. The structures and contents of 24 science textbooks of the middle school developed by the sixth curriculum were analyzed and compared each other. The following results were obtained: 1. The 3 serial textbooks, ScienceⅠ,Ⅱ and Ⅲ, dealed with motion and energy, materials, life and earth in the knowledge area. As the contents were divided into 4 courses such as earth science, biology, chemistry and physics, biology course was more emphasized than the other courses. Although the inquiry area of science textbooks was emphasized chiefly on the experiments, biology course focused mainly on the observations. 2. In the contents of biology course, the themes were stressed on "structure and function (34.5%)", "living things and environment (17%)", and "diversity and unity (14.9%)" and "genetic continuity (14.6%)" in order of emphasis degree, and were based on "diversity and unity" in Science 1, "structure and function" in Science 2, and "living things and environment" in Science 3. The levels on "individual (37.4%)", "tissue and organ (24.4%)" and "biosphere (17%)" were stressed in order, and were concentrated mainly in Science 1, 2 and 3, respectively. 3. The illustration and picture were contained 0.8 in number per a page in the biology course. And the illustration and picture representing external structure, internal structure, and method of experiment were contained primarily in the Science 1, 2 and 3, respectively.

      연관 검색어 추천

      이 검색어로 많이 본 자료

      활용도 높은 자료

      해외이동버튼