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악교정 수술후 자가통증조절장치(Patient-Controlled Analgesia)의 사용 효과에 관한 연구
양병은,유준영,송상훈,엄기훈 大韓顎顔面成形再建外科學會 1999 Maxillofacial Plastic Reconstructive Surgery Vol.21 No.4
The concept of PCA(Patient Controlled Analgesia) was first described in 1968, by Sechzer. The earliest descriptions of actual self-administered PCA machines were by Forrest et al. In gastric bypass surgery, cesarian section, orthopedic surgery etc, PCA is widely used in the control of postoperative pain. Previous Studies have shown that PCA provides effective pain-control for the postoperative patient. The postoperative pain-control is a problem that should be solved in surgery. Especially in orthognathic surgery, it is not same as in the case of maxillofacial trauma surgery or of tumor surgery : most orthognathic surgery patients are under operation not accustomed to pains, and difficulties in pain-complaint due to IMF(Intermaxillary fixation), postoperative nausea, and vomiting are additional problem. In this study, we have compared PCA and IM analgesics with respect not only to time request but also to the quality of postoperative pain control.
유준영,양병은,송상훈,엄기훈 大韓顎顔面成形再建外科學會 1999 Maxillofacial Plastic Reconstructive Surgery Vol.21 No.4
The nasal and zygoma bone are parts of frequently fracturing of facial bones because of anatomically protrusion. Of facial bone fractures, nasal bone is at the high level of incidence rate. But zygoma fracture that anatomical characteristics increase the incidence rate also is occupied considerable part of the facial bone fracture. The outline of face is decided by form of underlying skeletal structure, of that, zygoma plays an important role in. Zygoma is closely attached to surrounding anatomic structure as orbit, maxillary sinus. Aesthetic and functional disturbance are developed by zygoma fracture from trauma, complications, as facial asymmetry, trismus, sensory disturbance, epistaxis, periorbital hemorrhage, diplopia etc, are developed. The patterns of complications following displacement of fractured fragment of zygoma by trauma are slightly different.
엄병헌,김주선,안병태,강삼식,Um, Byung-Hun,Kim, Ju-Sun,Ahn, Byung-Tae,Kang, Sam-Sik 한국생약학회 1997 생약학회지 Vol.28 No.1
From the Evodiae Fructus, four flavonoids were isolated and identified as cacticin, limocitrin $3-0-{\beta}-D-galactoside$, hyperin and diosmin by means of chemical and spec-troscopic methods.
B형 간염 백신의 접종 횟수에 따른 항체 생성률에 대한 고찰
한혜경,엄미령,이성자,최경훈,이미나,유병훈 대한감염학회 1996 감염 Vol.28 No.1
목적 : B형 간염 혈장백신에 의한 항체 양성률은 90-95% 이상으로 보고되고있고 저자마다 결과의 차이가 있었다. 또한 동일개체 내에서 항체가 변화에 대한 연구가 많지 않아 저자들은 동일 개체에서의 시간경과에 따른 항체가 변화와 B형 간염백신접종 후 항체가 형성되지 않았던 아동들에게 백신 재접종 후 항체가와 항체양성률이 어떻게 변화하는지 알아보고자 본 연구를 시도하였다. 방법: 1994년 3월부터 1995년 6월까지 제일병원에서 B형 간염백신(HepavaxR)을 출생시, 1개월, 6개월에 접종받은 소아중 934명을 대상으로하여 생후 9개월에 항원(HBsAg), 항체가(Ant-HBs titer)를 측정하여 이중 항체가 형성되지 않은 소아에게 1회 추가접종후 4주후에 다시 항체가를 측정하였다. 이중 항체가 형성안된 소아에게 5차, 6차 접종후 3개월후에 다시 항체가를 측정하였다. 이들중 HBsAg양성 산모의 소아들에겐 생후 3개월 때 항원, 항체 검사를 실시 하였다. 검사방법은 RIA(radioimmunoassay:Abbott Laboratories)로 하였다. 결과: 1)2차 백신접종후(간염항원 양성 산모의 소아들중 생후 3개월인 소아) 검사한 HBsAb역가가 10mIU/ml 이상인 경우는 63명중 22명(34.9%)이었고 이중 항체가 형성안된 아동중 4차 접종후 검사가 시행된 172명중 101명(58.7%)이 10mIU/ml 이상이었다. 5차, 6차 백신접종후 검사가 시행된 13명중 4명이 10mIU/ml이상이었다. 2) 4차 백신 접종후 누적 항체양성률은 90.8%였고, 6차 백신 접종후는 98.7%였다. 결론: 3차 백신 접종후 항체 음성인 소아에게 4차 접종후 항체양성률이 증가되었다. B형 간염 백신 3차 접종후 선별 검사를 실시하여 항체 음성인 아동에게 추가접종이 필요할것으로 생각된다. Background : The seroconversion rate of hepatitis B after three consecutive vaccinations is estimated to be approximately 90%. We have given booster injections to the seronegative children with the fourth, fifth or sixth vaccination and estimated the seroconversion rate of hepatitis B (?? : Korean Green Cross Corporation) in relation to the number of vaccination. Methods : Serum samples were obtained from 934 babies who visited Cheil Hospital at 9 months of age (3 months after the 3rd vaccination) to determine the presence of HBsAg and titer of anti-HBs. The cases of negative anti-HBs were given a booster dose and anti-HBs titer was tested 4 weeks later. The babies who still had negative anti-HBs after the 4th dose were given the 5th and the 6th doses and anti-HBs titer was tested. RLA (Abbott Laboratories, U.S.A.) was used to determine the titers of anti-HBs. Seventy-eight babies born yo mothers who were HBsAg-positive were tested for HBsAg and titers of anti-HBs at 3 months of age after the 2nd vaccination. Results: 1) Twenty-two babies out of 64(34.9%) showed seroconversion after the 2nd vaccination. Six hundred babies out of 893(67.2%) showed seroconversion after the 3rd vaccination. Among the babies who were given the 4th dose 101 out of 172 (58.7%) babies showed seroconversion and for the 6th dose 4 out of 13 babies. 2) Cumulative seroconversion rate was 90.8% and 98.7% after the 4th and 6th vaccination, respectively. 3) The geometric mean titer (GMT) of anti-HBs was 19.2mIU/ml after the 2nd vaccination, 112.7mIU/ml after the 3rd vaccination and 57.1mIU/ml after the 4th vaccination. Conclusion : Seroconversion rate increased after the 4th dose for the babies who had negative anti-HBs even after the 3rd vaccination. Therefore, we recommend to screen for anti-HBs after the 3rd vaccination and to give booster injections for those who are negative anti-HBs.