심폐소생술중 심실기능 및 판막운동의 평가

이부수,김영식,이강현,황성오,임경수,박금수,윤정한,안무업,최경훈 대한응급의학회 1994 대한응급의학회지 Vol.5 No.2

Background : Mechanism of blood flow during cardiopulmonary resuscitation(CPR) in humans remains controversial and poorly understood, although cardiac or thoracic pump theory was proposed. We investigated cardiac movement, ventricular function and atrioventricular valve motion with aid of transesophageal echocardiography during precordial compression during CPR in humans. Methods and results : During CPR transesophageal echocardiography was performed in 14 patients with non-traumatic cardiac arrest. Manual precordial compression during CPR was performed according to American Heart Association guidelines. Mitral valve closed in 9 and did not close in 5 patients during "compression systole". Tricuspid valve closed during compression systole. Compression vector directed to right ventricle, basal portion of interventricular septum and left atrium. The heart rotated clockwise and the apex was more displaced than the base("swing motion"). Fractional shortening(FS) and ejection fraction(EF) of right ventricle exceeded those of left ventricle(FS : 55±9% vs 18±8%, p<0.05), EF : 79±9% vs 37±16%, p<0.05). FS and EF of left ventricle was higher in patients with systolic mitral valve closure than patients with persistent systolic opening of mitral valve(FS : 21±7 vs 13±7%, EF : 45±12 vs 22±12%, p<0.05), but FS and EF of right ventricle was not different. Conclusion : During precordial compression, the heart rotated clockwise and displaced. Systolic function of right ventricle exceeded left ventricle. Marked compression of right ventricle and systolic closure of tricuspid valve suggested that right ventricle functioned as a pump generating blood flow during precordial compression. Closure of mitral valve was dependant on systolic function of the left ventricle.

민들레 추출액 농도에 따른 민들레 코팅쌀밥의 품질에 관한 연구

유경미,이연경,김세희,황인경,이부용,김성수,홍희도,김영찬 한국조리과학회 2005 한국식품조리과학회지 Vol.21 No.1

Washed rice was coated by spraying aqueous dandelion (Taraxacum officinale) extracts at 20, 30, 40 'Brix and dried at room temperature. The coating procedure was conducted 5 mL/min for 10min. Property changes in the dandelion coated rice and un-coated cooked rice were observed during 2 days of storage. Increasing the coating concentration was associated with lower color values (L, a value) and moisture contents. Sensory and texture properties generally decreased in the cooked rice coated with dandelion more than the control (non-coated rice). But, D-20(20 °Brix of the dandelion concentration) resulted in better textural properties and s ensnry scores for hardness and overall acceptability in cooked rice. Compared to the control, the washed rice roated with 20 °Brix for 0 and 2 days showed better quality in sensory activities, a lower gel consistency and better textural activities. It was concluded that the optimum coating ration of rice and added dandelion extract for cooking were 20 °Brix and 5% respectively, in proportion to the total weight of raw rice.

심정지환자에서 epinephrine투여시 혈중 catecholamine의 변화

임경수,황성오,이부수,이강현,이진웅,임종천,김영식,김선만,김 현 대한응급의학회 1995 대한응급의학회지 Vol.6 No.1

Background : Cardiac arrest is a potent stimulus for the release of endogenous catecholamine and high plasma catecholamine concentration has been reported during cardiopulmonary resuscitation(CPR). Few data were present about the clinical effect of high plasma catecholamine and endogenous catecholamine response to exogenous epinephrine administration during CPR. Purpose : This study was designed to evaluate endogenous catecholamine response to cardiac arrest and exogenously administered epinephrine during CPR. Method : In 21 cardiac arrest victims, blood sample for epinephrine and norepinephrine was drawn before and 1 minute after each epinephrine administration during CPR. 1mg of epinephrine was administered immediately after intravenous access and 3 minute interval during CPR. Plasma catecholamines were quantitated by high-performance liquid chromatography. Result : Baseline plasma epinephrine concentraqtion was higher in patients with cardiac arrest than normal controls (985±1627 vs 194±173 pg/ml, p<0.05). Baseline plasma norepinephrine concentration was also elevated in patients with cardiac arrest than normal controls, although statistically insignificnat(1965±4915 vs 360±250 pg/ml). Plasma epinephrine concentration in cardiac arrest patients was significantly elevated after exogenous administration of epinephrine, but its response was blunted after the third does of epinephrine. Plasma norepinephrine concentration in cardiac arrest patients was also elevated, but its response was observed only after the first epinephrine administration. Plasma epinephrine concentration was persistently higher in patients with return of spontaneous circulation (ROSC) than patients without ROSC. there was no significant difference of plasma norepinephrine concentration whether spontaneous circulation was restored or not. Endogenous epinephrine response to exogenous epinephrine was not observed in patients having prolonged arrest time over 20 minutes. Conclusion : Results of this study suggests that significant amount of catecholamine is released by exogenous epinephrine administration in spite of high plasma catecholamine concentration, and degree of endogenous catecholamine response influences resuscitation outcome.

전도성 고분자 센서 어레이를 이용한 휘발성 유기 화합물 가스 인식

이경문,주병수,유준부,황하룡,이병수,이덕동,변형기,허증수 한국센서학회 2002 센서학회지 Vol.11 No.5

휘발성 유기 화합물 가스(Volatile Organic Compounds)를 인식하고 분석하기 위하여 전도성 고분자 센서어레이를 이용한 시스템을 제작하였다. Polypyrrole와 Polyaniline을 화학중합법으로 센서에 전도성고분자막을 형성하였고 이를 통해 VOC 검지용 센서 어레이를 제작하였다. 센서어레이로부터 측정되는 다차원 데이터는 주성분분석법(PCA)과 RBF(Radial Basis Function Network)을 이용하였다. 제안된 시스템으로 VOCs 가스를 인식하는데 있어서 RBF Network이 PCA방식보다 더욱 효율적인 것으로 판단되었다. We fabricated gas recognition system using conducting polymer sensor array for recognizing and analyzing VOCs(Volatile Organic Compounds) gases. The polypyrrole and polyaniline thin film sensors which were made by chemical polymerization were employed to detect VOCs. The multi-dimensional sensor signals obtained from the sensor array were analyzed using PCA(principal component analysis) technique and RBF(radial basis function) Network. Throughout the experimental trails, we confirmed that RBF Network is effective than PCA technique in identifying VOCs.

응급센터내에서의 Do-Not-Resuscitate Order

김영식,황성오,이부수,안무업,임경수,강성준 대한응급의학회 1993 대한응급의학회지 Vol.4 No.2

Do-not-resuscitate(DNR) decision in certain patients is a important part of patient management. The use of DNR order has been widely recognized in hospitalized patients, but there has been little discussion of the use of DNR order in emergency department. DNR decision in emergency department is difficult because there is no previous contact between physician and patient. To identify the medical reasons of the DNR decision and the process of the DNR in the emergency department, 293 DNR patients in emergency department during 1 year and 36 physicians having experienced DNR decision were studied. Reasons for DNR are irreversible states from brain damage or acute illness(63%), chronic irreversible illness(15%), prolonged cardiac arrest over 30 minutes(16%), physical injuries including decapitation(1%) and family's hope(5%). Almost DNR(72%) were decided by physicians. 72% of DNR decision were not documented. Cardiopulmonary resuscitation was attempted before DNR decision in 38% of the patients and 17% of CPR attempts were unnecessary. Almost physician(88%) replied that physician should discuss resuscitation with family and process of DNR decision should be documented.

Paraquat 중독환자의 초기검사로서 sodium dithionite를 이용한 소변내 paraquat검출의 임상적 의의

윤갑준,임경수,이진웅,김영식,이부수,박덕우,김선만,이강현,황성오,안무업 대한응급의학회 1995 대한응급의학회지 Vol.6 No.1

Background : Mortality from paraquat intoxication depends upon plasma paraquat concentration. To know the severity of paraquat intoxication is important for directing therapeutic modality and predicting prognosis. Sodium dithionite test for urinary paraquat provides an easy and simple method to determine the severity of paraquat intoxication in emergency department. purpose : To determine whether the result urinary paraquat test by sodium dithionite can predict outcome in patients with paraquat intoxication in emergency department. Subjects : 48 patients(male 31, female 17, mean age 37 years) who had exposure to paraquat and presented within 24 hours after exposure. Result : Thirty five patients were positive in paraquat urine test and thirteen patients were negative. Clinical manifestations were more severe in positive patients than in negatives. Complication was much more in positives than in negatives. 28 of 35 patients(80%) in positives and 2 of 13 patients(15%) in negatives died. Conclusion : Positive test for urinary paraquat is associated with high mortality and morbidity from paraquat intoxication, and qualitative test for urinary paraquat by sodium dithionite is an useful method to determine the severity of paraquat intoxication in emergency department.

Dispatcher(전화 상담원)의 보조에 의한 심폐소생술

안무업,김영식,이부수,황성오,임경수 大韓應急醫學會 1992 대한응급의학회지 Vol.3 No.1

Background: Dispatcher-assisted telephone instruction in cardiopulmonary resuscitation(CPR) has been proposed to increase rates of bystander CPR in cases of out-of-hospital cardiac arrest. In Korea, bystanders do not know how they resuscitate the victims and EMS(Emergency Medical System) is incomplete. Study Objectives: This study was undertaken to tested the efficacy of dispatcher assisted telephone CPR using a recording mannikin(Anne Resusci) in a highstress, simulated cardiac arrest scenario. Study Subjects: We assesed in a group of volunteers, without prior CPR lectured and training(GroupⅠ, n=20), without prior CPR training but received lecture previously(Group Ⅱ, n=20) who received telephone instruction were compared with that of previously recevied lecture and tranined(Group Ⅲ, n=20) who received same massage. Performances of above groups were also compared with a group(Group Ⅳ, n=20) composed of previously received lecture and trained volunteers who did not receive the massage. Results: Members of groups Ⅰ,Ⅱ, and Ⅲ delivered similar average ventilation volumes, approximately 1L/cycle. In contrast, group Ⅳ delivered somewhat less, about 700ml/cycle(p<0.05). Group Ⅰ performed ventilation better than group Ⅳ but there was no significant intergroup differences in the performing effective chest compressions. The global performance of group Ⅲ, the group with prior CPR lecture, trained and telephone instruction, was superior to that achieved by other groups(p<0.05). We conclude that dispatcher-assisted telephone CPR can offer a safe and cost-effective means to increase the rate of bystander CPR and also improves the quality of CPR performed by persons with prior CPR training.

STUDY ON HYDRODEOXYGENATION OF GUAIACOL WITH PALLADIUM BASED CATALYSTS

Kyung-Ran HWANG,Sung-Mi JI,Chun-Boo Lee,Jong-Soo Park,In-Gu LEE 한국신재생에너지학회 2013 AFORE Vol.2013 No.-

Transient Liquid Phase Sintering of Ni and Sn-58Bi on Microstructures and Mechanical Properties for Ni–Ni Bonding

Kyung Deuk Min,Kwang-Ho Jung,Choong-Jae Lee,Haksan Jeong,Byeong-Uk Hwang,Seung-Boo Jung 대한금속·재료학회 2020 ELECTRONIC MATERIALS LETTERS Vol.16 No.4

Transient liquid phase sintering (TLPS), which is a combined bonding technology of sintering and transient liquid phase bonding, is considered to be a promising sic. die attach material owing to its excellent mechanical properties and low cost. To prevent the oxidation problem, Ni is typically plated onto direct bonded copper and sic. chip. In this study, we investigated the Ni–Ni bonding by adapting TLPS method using Ni and Sn-58Bi. The bonding temperature and time were 220 °C and 60 min, respectively. In addition, the bonding atmosphere was maintained in air without bonding pressure. To confirm the bonding reliability, high-temperature storage test was conducted at 200 °C for 1000 h. With an increase in the remelting temperature to 271 °C, the bonding strength of the TLPS joint of 20 wt% Ni case was about 15 MPa. In addition, the bonding strength decreased by approximately 32% after the high-temperature storage test for 1000 h. In conclusion, Ni–Ni bonding was successfully achieved by the TLPS of Sn-58Bi with Ni.

급성심근경색환자에서 최초증상으로부터 재관류요법결정까지의 시간경과

황성오,임경수,이부수,김영식,안무업,유병수,윤정환,박금수,최경훈 대한응급의학회 1994 대한응급의학회지 Vol.5 No.1

To investigate the potential causes of delays between onset of chest pain and provision of reperfusion therapy. We measured time intervals of prehospital phase and in emergency department in 149 patients with acute myocardial infarction. Data were collected by interview with patients for prehospital time delays and time records in emergency department. The results were followings : Patients who admitted to our hospital prior to 6 hours from chest pain were 519(34%). Mean prehospital dealy time of total patients was 548 minutes. Mean prehospital delay time of direct visit patients was shorter than transported patients(357 vs 595 minutes, p<0.05). In direct visit patients, patient delay time was shorter in reperfusion group than non-reperfusion group(117 vs 481 Minutes, p<0.001). In transported patients, patients dealy time and first hos-pital delay time were shorter in reperfusion group than non-reperfusion group(116 vs 294 minutes in patient dealy time, 70 vs 227 minutes in first hospital dealy time, p<0.05 respectively). Transportation time and dealy time in emergency department were not different between both groups. In conclusion, time dealys in patients not receiving reperfusion therapy was attributed to prolonged patient delay time and first hospital dealy time in prehospital phase.