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Chang, Boksoon,Han, Seo Goo,Kim, Wooyoul,Ko, Yousang,Song, Junwhi,Hong, Goohyeon,Eom, Jung Seop,Lee, Ji Hyun,Jhun, Byung Woo,Koh, Won-Jung The Korean Academy of Tuberculosis and Respiratory 2013 Tuberculosis and Respiratory Diseases Vol.75 No.1
Carbohydrate antigen 19-9 (CA 19-9) is a widely-used tumor marker in patients with pancreatic cancer. However, some patients with respiratory disease also exhibit elevated serum CA 19-9 levels. We report a case of normalization of elevated serum CA 19-9 levels after treatment of the nodular bronchiectatic form of Mycobacterium abscessus lung disease. A 40-year-old man visited our hospital because of chronic cough and sputum. A computed tomography scan revealed severe bronchiectasis in the right upper and right middle lobes. Nontuberculous mycobacteria were repeatedly isolated and identified as M. abscessus. The serum CA 19-9 level was elevated to 142.35 U/mL (normal range, <37 U/mL). Surgical resection was performed because of failure of sputum conversion after antibiotic treatment. The serum CA 19-9 level returned to the normal range after surgery. This case suggested that serum CA 19-9 levels could be elevated in patients with the nodular bronchiectatic form of M. abscessus lung disease.
A Case of Pleural Paragonimiasis Confused with Tuberculous Pleurisy
Song, Junwhi,Hong, Goohyeon,Song, Jae-Uk,Kim, Wooyoul,Han, Seo Goo,Ko, Yousang,Chang, Boksoon,Jeong, Byeong-Ho,Eom, Jung Seop,Lee, Ji Hyun,Jhun, Byung Woo,Jeon, Kyeongman,Kim, Hong Kwan,Koh, Won-Jung The Korean Academy of Tuberculosis and Respiratory 2014 Tuberculosis and Respiratory Diseases Vol.76 No.4
Here, we report a case of pleural paragonimiasis that was confused with tuberculous pleurisy. A 38-year-old man complained of a mild febrile sensation and pleuritic chest pain. Radiologic findings showed right pleural effusion with pleural thickening and subpleural consolidation. Adenosine deaminase (ADA) activity in the pleural effusion was elevated (85.3 IU/L), whereas other examinations for tuberculosis were negative. At this time, the patient started empirical anti-tuberculous treatment. Despite 2 months of treatment, the pleural effusion persisted, and video-assisted thoracoscopic surgery was performed. Finally, the patient was diagnosed with pleural paragonimiasis based on the pathologic findings of chronic granulomatous inflammation containing Paragonimus eggs. This case suggested that pleural paragonimiasis should be considered when pleural effusion and elevated ADA levels are observed.
( Byeong Ho Jeong ),( Jae Uk Song ),( Wooyoul Kim ),( Seo Goo Han ),( Yousang Ko ),( Junwhi Song ),( Boksoon Chang ),( Goohyeon Hong ),( Su Young Kim ),( Go Eun Choi ),( Sung Jae Shin ),( Won Jung Koh 대한결핵 및 호흡기학회 2013 Tuberculosis and Respiratory Diseases Vol.74 No.4
We report a rare case of lung disease caused by Mycobacterium lentiflavum in a previously healthy woman. A 54-year-old woman was referred to our hospital due to chronic cough and sputum. A computed tomography scan of the chest revealed bilateral bronchiectasis with bronchiolitis in the right middle lobe and the lingular division of the left upper lobe. Nontuberculous mycobacteria were isolated twice from three expectorated sputum specimens. All isolates were identified as M. lentiflavum by multilocus sequence analysis based on rpoB, hsp65, and 16S rRNA fragments. To the best of our knowledge, this is the first documented case of M. lentiflavum lung disease in an immunocompetent adult in Korea.
Jeong, Byeong-Ho,Song, Jae-Uk,Kim, Wooyoul,Han, Seo Goo,Ko, Yousang,Song, Junwhi,Chang, Boksoon,Hong, Goohyeon,Kim, Su-Young,Choi, Go-Eun,Shin, Sung Jae,Koh, Won-Jung The Korean Academy of Tuberculosis and Respiratory 2013 Tuberculosis and Respiratory Diseases Vol.74 No.4
We report a rare case of lung disease caused by Mycobacterium lentiflavum in a previously healthy woman. A 54-year-old woman was referred to our hospital due to chronic cough and sputum. A computed tomography scan of the chest revealed bilateral bronchiectasis with bronchiolitis in the right middle lobe and the lingular division of the left upper lobe. Nontuberculous mycobacteria were isolated twice from three expectorated sputum specimens. All isolates were identified as M. lentiflavum by multilocus sequence analysis based on rpoB, hsp65, and 16S rRNA fragments. To the best of our knowledge, this is the first documented case of M. lentiflavum lung disease in an immunocompetent adult in Korea.