장벽경색이 선행한 Henoch-Schonlein 자반증 1례

한헌석,하태선,송형근,이상전,안묘순,박범수 충북대학교 의과대학 충북대학교 의학연구소 1993 忠北醫大學術誌 Vol.3 No.1

Henoch-Schonlein 자반증은 피부, 위장관, 관절, 신장 등을 주로 침범하며 소혈관염을 기본 병리 소견으로하는 전신성 혈관 장애 질환이다. 위장관계 증상으로는 복통, 오심 및 구토, 잠혈, 토혈, 흑색변 등이 있을 수 있고, 이러한 증상은 합병증 없이 회복되는 것이 보통이나 드물게는 장중첩증, 장벽경색 및 괴사, 장천공 등의 심한 합병증을 동반할 수도 있다. 이러한 위장관계 증상들은 특징적인 피부 소견에 선행하여 나타날 수도 있으며, 이때는 급성복증에 대한 감별진단이 중요하다. 저자들은 장벽경색이 선행하여 감별진단에 어려움을 겪고 시험적개복술을 시행한 이후에 특징적인 피부 자반이 발현되어 Henoch-Schonlein 자반증으로 진단할 수 있었던 증례를 경험하였기에 이를 보고하고자 한다. 본 증례는 입원 1일전부터 시작된 복통을 주소로 입원한 5세 남아가 배꼽 주위에 심한 경련성 복통을 지속적으로 호소하였고 이학적 소견상 배꼽주위의 압통, 장음의 감소, 흑색변 등이 있었으며 소장조영술상 공장 부위에 미만성의 불규칙한 점막비후 소견을 보여 제 8병일에 시험적개복술을 시행한 결과 근위 공장에 국한된 장괴사의 소견이 발견되어 절제 및 문합술을 실시 하였다. 병리학적 검사에서는 장벽경색의 소견을 보였다. 수술후에 복통은 완화되었으나 경미하게 지속되었고, 제 13병일경에 급성 부고환염이 병발되었다가 회복되었고 제 15병일경에는 하지에서부터 발현된 자반이 3일간 지속되었다. 결구 Henoch-Schonlein 자반증과 이의 합병증으로 발생한 근위 공장의 장벽경색으로 진단하였다. Colicky abdominal pain as symptom of Henoch-Schonlein purpura occurs in up to 70% of patients, and results from submucosal edema and hemorrhage. Abdominal pain and other GI symptoms such as nausea, vomiting, melena and hematemesis resolve mostly without any complications. But rarely life-threatening GI complications such as intussusception, intestinal mural infarction and necrosis, and massive hemorrhage may develope. In 14% of patients, abdominal pain may precede other symptoms, and creats diagnostic difficulties. We reports a case of the Henoch-Schonlein purpura presented with colicky abdominal pain which resulted from intestinal mural infarction and preceded characteristic purpuric skin lesion by several weeks. This 5 year old male patient complained of colicky abdominal pain, nausea and melena. Exploratory laparatomy was done and revealed intestinal mural infarction in proximal jejunum. One week later operation, purpuric skin lesion develiped in both leg and feet, and then, Henoch-Schonlein purpura was diagnosed.

Castleman 질환 1례

안묘순,송형근,박범수,한헌석,하태선 충북대학교 의과대학 충북대학교 의학연구소 1993 忠北醫大學術誌 Vol.3 No.1

Castleman 질환은 주로 종격동 임파선을 침범하여 임상적, 조직학적으로 흉성종과 유사한 소견을 보이는 질환이다. 보통 침범된 임파선은 3cm에서 7cm의 크기를 보이며 경계가 뚜렷한 종양으로 나타난다. 조직학적 소견상 hyaline-vascular형(H-V형)과 plasma cell형의 두가지로 나눈다. 임상적으로는 hyaline-vascular형은 별증상이 없으며 보통 우연히 발견되고 드물게 기도와 기관지를 압박하는 증세를 보이기도 한다. plasma cell형은 빈혈, 적혈구침강속도의 증가, 고감마글로불린혈증, 저알부민혈증, 그리고 저트란스페린혈증을 보이기도 한다. 저자들은 생후 2개월부터 반복되는 호흡기 감염과 거친 숨소리를 보이면서, 성장 및 발육장애를 보인 14개월된 남아에서, 기도에서 우측 주기관지까지를 압박하고 있는 종양을 흉부 전산화단층촬영에서 발견하고 떼어낸 후 조직소견상 hyaline-vascular형의 giant lymph node hyperplasia의 소견을 보이는 Castleman 질환 1례를 경험하였기에 보고하는 바이다. Castleman's disease(angiofollicular lymph node hyperplasia) can arise from lymph nodes or extranodal tissues and can be classified histologically into the hyaline-vascular form, characterized by hyaline follicle-like structures interspersed with vascular tissue, or the plasma cell variant, in which the follicle-like structures are seperated by sheets of plasma cells amidst vascular interfollicular tissue. The clinical manifestations of the multicentric variant can be protean and inculude fever, night sweats, weight loss, lymphadenopathy, hepatosplenomegaly, pleural effusion, ascites, anemia, thrombocytopenia, polyclonal hypergammaglobulinemia, and neurological and renal abnormalities. We report a case of Castleman's disease in 14-month old male patient with the chief complaints of recurrent respiratory symptoms and delayed growth and development, who was diagnosed as having a hyaline-vascular form of above disease after the excision of pulmonary mass which compressed the right main bronchus.

빛에 대한 국민학교 학생들의 개념조사

김한호,권재술,김범기,정진우,최병순 한국교원대학교 과학교육연구소 1992 청람과학교육연구논총 Vol.2 No.1

The purpose of this study was to investigate children's(K-5) conceptions about light in Korea. The two aspect of children's conceptions about light were identified: the sources of light, the nature of vision. Data were collected from 92 children by a mixture of writing, drawing and interview, and were analysed by systematic networks. The major findings of this study were as follows: 1. Children showed an awareness of a wide variety of sources of light. The predominant sources exampled by children were primary sources. 2. Children explained vision as intentional of seeing Seeing. means action that move their heal or eyes to the objects. Infants(K-1) did not recognize that light are needed for vision. 3. A notable features in children's conceptions about light were context-dependent

빛에 대한 국민학교 학생들의 개념조사

김한호,정진우,최병순,김범기,권재술 한국교원대학교 과학교육연구소 1993 청람과학교육연구논총 Vol.3 No.1

The purpose of this study was to investigate children's(K-5) conceptions about light in Korea. The two aspect of children's conceptions about light were identified: the sources of light, the nature of vision. Data were collected from 92 children by a mixture of writing, drawing and interview, and were analysed by systematic networks. The major findings of this study were as follows: 1. Children showed an awareness of a wide variety of sources of light. The predominant sources exampled by children were primary sources. 2. Children explained vision as intentional actvivty of seeing Seeing. means action that move their heal or eyes to the objects. Infants(K-1) did not recognize that light are needed for vision. 3. A notable features in children's conceptions about light were context-dependent

정신과 폐쇄 병동 환경 평가에 영향을 미치는 임상변인 : 치료의 질적 향성을 위한 예비적 연구 The Preliminary Study for Promoting the Quality of Psychiatric Inpatient Treatment

서정석,류은정,이상미,한미희,최귀순,손인기,남범우 건국대학교 의과학연구소 2003 건국의과학학술지 Vol.13 No.-

Purpose: IS prelminary study was designed to assess the clinical variables influencing on the ward atmosphere in psychiatric closed ward and to promote the quality of psychiatric inpatient treatment. Method: 41 psychiatric inpatients were selected in Chung-ju hospital, Konkuk university. Ward Atmosphere Scale(W AS) was used to evaluate patients' perception of ward milieu. WAS score were compared among subgroups with respect to the clinical variables such as duration of admission, frequency of admission, and diagnosis. Results: Significantly, patients who have hospitalized for 1 month to 2 months reported lower score of WAS and patients who have hospitalized for longer than 2 months reported higher score of WAS. The relationship between educated levels and WAS score was not significant. First admitted patients reported significantly lower score of WAS. Bipolar patients reported significantly higher score of WAS and alcohol related patients reported significantly lower score of WAS. Conclusion: The 1st admitted patients, patients with alcohol problem and educated patients were had less satisfied with psychiatric closed ward. Thus, by considering these factors, more specified therapeutic approach and plan should be conducted.

Environmental factors affecting development of Aspergillus nidulans

Han, Kap-Hoon,Lee, Dong-Beom,Kim, Jong-Hak,Kim, Min-Su,Han, Kyu-Yong,Kim, Won-Shin,Park, Young-Soon,Kim, Heui-Baik,Han, Dong-Min The Microbiological Society of Korea 2003 The journal of microbiology Vol.41 No.1

Aspergillus nidulans, a homothalic ascomycete, has a complete sexual reproductive cycle as well as an asexual one. Both sexual and asexual development are known to be genetically programmed, but are also strongly affected by environmental factors including nutrients, light, temperature and osmolarity. We have examined these factors to define favored conditions for fruiting body (cleistothecium) formation. In general, fruiting body formation was enhanced where carbon and nitrogen sources were sufficient. Limitation of C-source caused predominant asexual development while inhibiting sexual development. When higher concentrations of glucose were supplied, more cleistothecia were formed. Other carbon sources including lactose, galactose and glycerol made the fungus develop cleistothecia very well, whereas acetate caused asexual sporulation only. Organic nitrogen sources like casein hydrolysate and glycine, and an increase in nitrate or ammonium concentration also enhanced sexual development. In addition to nutrient effects, low levels of aerobic respiration, caused either by platesealing or treatment with various chemicals, favored sexual development. Carbon limitation, light exposure and a high concentration of salts promoted asexual development preferentially, suggesting that stress conditions may drive the cell to develop asexual sporulation while comfortable and wellnourished growth conditions favored sexual development.

Air Quality Change in Korea under COVID-19 Social Distancing: Focusing on PM<SUB>2.5</SUB>

Beom-Soon Han,Kyeongjoo Park,Kyung-Hwan Kwak,Seung-Bu Park,Han-Gyul Jin,Sungju Moon,Jong-Won Kim,Jong-Jin Baik 한국기상학회 2020 한국기상학회 학술대회 논문집 Vol.2020 No.10

Large-eddy simulation of vortex streets and pollutant dispersion behind high-rise buildings : Vortex Streets and Pollutant Dispersion Behind High-rise Buildings

Han, Beom-Soon,Park, Seung-Bu,Baik, Jong-Jin,Park, Junho,Kwak, Kyung-Hwan John Wiley & Sons Ltd 2017 Quarterly journal of the Royal Meteorological Soci Vol.143 No.708

Structures of the wintertime lower troposphere in Seoul from 1-hr interval radiosonde observation and numerical simulations

Beom-Soon Han,Kyung-Hwan Kwak,Jae-Hee Hahm,Seung-Bu Park 한국기상학회 2022 한국기상학회 학술대회 논문집 Vol.2022 No.10

Large-eddy simulation of reactive pollutant exchange at the top of a street canyon

Han, Beom-Soon,Baik, Jong-Jin,Kwak, Kyung-Hwan,Park, Seung-Bu Elsevier 2018 Atmospheric environment Vol.187 No.-

<P><B>Abstract</B></P> <P>The exchange of reactive pollutants (NO, NO<SUB>2</SUB>, and O<SUB>3</SUB>) at the top (roof level) of a street canyon are investigated using the parallelized large-eddy simulation model (PALM). The transport equations of NO, NO<SUB>2</SUB>, and O<SUB>3</SUB> with simple photochemical reactions are combined within the LES model for this study. NO and NO<SUB>2</SUB> are emitted from an area source located near the canyon floor, and O<SUB>3</SUB> is included within the ambient air and inflow. A clockwise-rotating vortex appears in the street canyon and transports NO, NO<SUB>2</SUB>, and O<SUB>3</SUB>. NO and NO<SUB>2</SUB> are transported along the ground and leeward wall and escape from the canyon at the roof level. O<SUB>3</SUB> enters the canyon at the roof level and is transported along the windward wall. The mean O<SUB>3</SUB> production rate is generally negative with large magnitudes at and near the roof level and near the windward wall. The chemical reactions reduce the mean NO and O<SUB>3</SUB> concentrations in the canyon by 31% and 84%, respectively, and increase the mean NO<SUB>2</SUB> concentration in the canyon by 318%. The exchange of reactive pollutants at the roof level is significantly affected by small-scale eddies at the roof level and low- or high-speed streaks above the canyon. Air in the canyon with high NO and NO<SUB>2</SUB> concentrations escapes from the canyon when low-speed air parcel appears due to small-scale eddies at the roof level or low-speed streak above the canyon. In contrast, air outside the canyon with a high O<SUB>3</SUB> concentration enters the canyon when high-speed air parcel appears because of small-scale eddies at the roof level or high-speed streak above the canyon. The time-lagged correlation analysis reveals that NO, NO<SUB>2</SUB>, and O<SUB>3</SUB> concentrations near the ground are affected by low- or high-speed streaks above the canyon but not significantly affected by small-scale eddies at the roof level.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Reactive pollutant exchange in a street canyon is examined using an LES model. </LI> <LI> Small-scale eddies at the roof level affect reactive pollutant exchange. </LI> <LI> High- or low-speed streaks above the canyon affect reactive pollutant exchange. </LI> <LI> High- or low-speed streaks affect reactive pollutant concentration near the ground. </LI> </UL> </P>