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Atsushi Otsuka,Takahisa Suzuki,Yuto Matsushita,Hiromitsu Watanabe,Keita Tamura,Daisuke Motoyama,Toshiki Ito,Takayuki Sugiyama,Hideaki Miyake 대한배뇨장애요실금학회 2019 International Neurourology Journal Vol.23 No.4
Purpose: To evaluate whether hydrodistention with fulguration of Hunner lesions (HD/FUL) plus maintenance dimethyl sulfoxide (DMSO) therapy prolongs the recurrence-free time in patients with Hunner type interstitial cystitis (IC). Methods: The study enrolled patients with Hunner type IC who required repeat HD/FUL due to recurrence of IC symptoms after the first HD/FUL at our institution. All patients received a second HD/FUL plus maintenance DMSO therapy. The maintenance DMSO therapy was performed every 2 weeks for a total of 8 instillations, and then once every 4 weeks thereafter. The recurrencefree time from HD/FUL to therapeutic failure was estimated using the Kaplan-Meier method. The recurrence-free time between the first HD/FUL and second HD/FUL plus maintenance DMSO therapy was statistically compared using the log-rank test. Results: A total of 21 patients (mean age, 66.3±10.8 years) with Hunner type IC were evaluated. The recurrence-free time for the second HD/FUL plus maintenance DMSO therapy was significantly longer than that for the first HD/FUL (P<0.0001). The median recurrence-free time for the first HD/FUL was 10.1 months, while that for the second HD/FUL plus maintenance DMSO therapy has yet to be reached. The recurrence-free rate for the first HD/FUL was 81.0% at 6 months, 38.1% at 1 year, 9.5% at 2 years, and 4.8% at 3 years. In contrast, the rate for the second HD/FUL plus maintenance DMSO therapy was 100% at 6 months, 94.7% at 1 year, 82.6% at 2 years, and 82.6% at 3 years. There were no significant differences in efficacy between the first and second HD/FUL. Conclusions: HD/FUL plus maintenance DMSO therapy clearly prolongs the recurrence-free time compared with HD/FUL alone in Hunner type IC.
Akihiro Tamura,Masafumi Kobune,Kazuki Imagawa,Hisashi Oshima,Yusuke Daiko,Atsushi Mineshige,Tetsuo Yazawa,Hiroshi Nishioka,Hironori Fujisawa,Masaru Shimizu,Hideshi Yamaguchi,Koichiro Honda 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.31
3.0-mm-thick a- and b-axis-oriented (Bi_(3.25)Nd_(0.75))Ti_3O_(12) (BNT-0.75) films were fabricated on conductive Nb:TiO_2(101) (Nb = 0, 0.048, 0.46, 0.79 mass%) single crystal substrates by high-temperature sputtering. A BNT films grown on undoped TiO_2 substrates have no orientation, whereas BNT films deposited on Nb:TiO_2 substrates with 0.46-0.79 mass% Nb show strong (h00/0k0) diffractions and grow with a heteroepitaxial relationship to the underlying Nb:TiO_2 substrates. The BNT-0.75 film deposited on Nb:TiO_2(101) substrate with 0.79 mass% Nb was indicated the peculiar shape of approximately 100-150-nm-thick nanoplates. We speculate that the driving force for producing a plate-like structure for BNT films is attributed to the large anisotropy of linear expansion coefficients for Bi_4Ti_3O12, and the comparatively small lattice matching between Nb:TiO_2 substrate and BNT film.
김재원,Atsushi Tamura,Sachiko Tsukita,박성수 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.99 No.-
Immature cell monolayers are vulnerable to tensile strain, which can cause severe diseases includingfibrosis, cancer, and atherosclerosis. However, little is known about how immature cell monolayersrespond to tensile strain. To study the effect of tensile strain on the morphology of cells in immaturemonolayers, we developed a miniaturized stretching device that allows stable real-time imaging ofchanges in cell shape induced by uniaxial static stretching of up to 20%. Upon stretching, the shape of cellsin the immature (2 day-cultured) monolayer changed dynamically, unlike in the mature (7 day-cultured)monolayer. Dynamic changes in the immature cell monolayers induced by tensile strain can be explainedby the increase in di-phosphorylated myosin light chain (pp-MLC), which initiates actomyosincontraction. We suggest that our stretching-observation system can be used to investigate themorphological response of epithelial cell monolayers to tensile strain.
Nakajima, Kyouhei,Umemura, Atsushi,Takahashi, Rion,Tamura, Junji Journal of International Conference on Electrical 2013 Journal of international Conference on Electrical Vol.2 No.3
As a number of wind power generation systems have been installed in power systems in the world, frequency fluctuations due to output power variations from wind farms have become a serious problem. Battery systems have been studied for smoothing the output variations and decreasing the resulting frequency fluctuations. Among these studies, efficient design of battery systems is one of the most important subjects from a point of view of cost. This paper presents a comparative analysis of the smoothing effect between the conventional moving average method and a new method based on frequency response analysis.
Masafumi Kobune,Hisashi Oshima,Akihiro Tamura,Kazuki Imagawa,Yusuke Daiko,Atsushi Mineshige,Tetsuo Yazawa,Hitoshi Morioka,Keisuke Saito,Hideshi Yamaguchi,Koichiro Honda 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.31
a- and b-axis-oriented (Bi_(3.25)Nd_(0.75))Ti_3O_(12) films, 3.0 mm thick, were fabricated on conductive IrO_2(101)/Al_2O_3(012) and Nb:TiO_2(101) [Nb = 0, 0.05 and 0.79 mass%] substrates by high-temperature sputtering. A BNT film grown on an IrO_2(101)/Al_2O_3(012) substrate had a low crystallinity (2.83˚), a low degree of a- and b-axis orientations [a_((h00/0k0)) = 49.2%] and a dense microstructure that a- and b-axis-oriented crystals existed locally in the film, while a BNT film grown on Nb:TiO_2(101) substrate with 0.79 mass% Nb showed a high crystallinity (0.57˚), a high a_((h00/0k0)) (99.9%) and a porous microstructure that was comprised of many nanoplate-like crystals. It is shown that the BNT film grew with a heteroepitaxial relationship to the underlying Nb:TiO_2 substrate has a symmetric loop shape, with a remanent polarization (2P_r) of 29 mC/cm^2 and a coercive field (2E_c) of 297 kV/cm.
Lane-Changing Feature Extraction Using Multisensor Integration
Hanwool Woo,Yonghoon Ji,Hitoshi Kono,Yusuke Tamura,Yasuhide Kuroda,Takashi Sugano,Yasunori Yamamoto,Atsushi Yamashita,Hajime Asama 제어로봇시스템학회 2016 제어로봇시스템학회 국제학술대회 논문집 Vol.2016 No.10
We propose a feature extraction method for lane changes of other traffic participants. According to previous research, over 90 % of car crashes are caused by human mistakes, and lane changes are the main factor. Therefore, if an intelligent system can predict a lane change and alarm a driver before another vehicle crosses the center line, this can using the multisensor system which consists of a position sensor and a laser scanner with line markings information. For a lane change prediction of other traffic participants, the most effective features are a lateral position and velocity with respect to a center line. We installed the sensor system to the primary vehicle and measured positions of other traffic participants while the primary vehicle drives on a highway. We extracted the features as the distance with respect to the center line and the lateral velocity of other vehicles using the measurement data. We confirmed that our feature extraction method has an enough accuracy for the lane change prediction.
Mitigation of Load Frequency Fluctuation Using a Centralized Pitch Angle Control of Wind Turbines
Junqiao, Liu,Rosyadi, Marwan,Takahashi, Rion,Tamura, Junji,Fukushima, Tomoyuki,Sakahara, Atsushi,Shinya, Koji,Yosioka, Kazuki Journal of International Conference on Electrical 2013 Journal of international Conference on Electrical Vol.2 No.1
In this paper an application of centralized pitch angle controller for fixed speed wind turbines based wind farm to mitigate load frequency fluctuation is presented. Reference signal for the pitch angle of each wind turbine is calculated by using proposed centralized control system based on wind speed information. The wind farm in the model system is connected to a multi machine power system which is composed of 4 synchronous generators and a load. Simulation analyses have been carried out to investigate the performance of the controller using real wind speed data. It is concluded that the load frequency of the system can be controlled smoothly.
Hideto Tada,Masafumi Kobune,Koji Fukushima,Hisashi Oshima,Daisuke Horit,Akihiro Tamura,Yusuke Daiko,Atsushi Mineshige,Tetsuo Yazawa,Hironori Fujisawa,Masaru Shimizu,Hideshi Yamaguchi,Koichiro Honda 한국물리학회 2009 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.55 No.2
The structural characteristics, the mechanism of crystal growth, and the ferroelectric properties of partially Sm-substituted perovskite bismuth-samarium-nickel-titanate [(Bi1−xSmx)(Ni0.5Ti0.5)- O3; BSNT, x = 0− 0.9] thin films deposited on Pt(100)/MgO(100) substrates by rf sputtering have been investigated using X-ray diffraction, transmission electron microscope, and polarization - electric field hysteresis loop measurements. The fabricated BSNT samples with x≥0.6 were confirmed to have a single-phase perovskite structure. Of the four samples (x = 0.6 0.7, 0.8, and 0.9) with a single-phase perovskite structure, the c-axis-oriented epitaxial BSNT film with x = 0.9 exhibited the best hysteresis loop, with a remanent polarization of 2 μC/cm2 and a coercive field of 100 kV/cm. The structural characteristics, the mechanism of crystal growth, and the ferroelectric properties of partially Sm-substituted perovskite bismuth-samarium-nickel-titanate [(Bi1−xSmx)(Ni0.5Ti0.5)- O3; BSNT, x = 0− 0.9] thin films deposited on Pt(100)/MgO(100) substrates by rf sputtering have been investigated using X-ray diffraction, transmission electron microscope, and polarization - electric field hysteresis loop measurements. The fabricated BSNT samples with x≥0.6 were confirmed to have a single-phase perovskite structure. Of the four samples (x = 0.6 0.7, 0.8, and 0.9) with a single-phase perovskite structure, the c-axis-oriented epitaxial BSNT film with x = 0.9 exhibited the best hysteresis loop, with a remanent polarization of 2 μC/cm2 and a coercive field of 100 kV/cm.