응급실에 내원한 국내 간질중첩증 소아의 발생율과 특성

신은주(Eun Ju Shin),황세희(Se Hee Hwang) 대한소아신경학회 2016 대한소아신경학회지 Vol.24 No.1

Purpose: Status epilepticus (SE) is the most common life-threatening neurological condition in childhood. To clarify the incidence and outcome, we have evaluated the epidemiological and clinical characteristics of SE patients in Korea. Methods: In evaluating data from the National Emergency Department Information System (NEDIS), we retrospectively analyzed patients, and classified them by age and sex distribution, body temperature, time on arrival, seasonal variation and treatment outcome. The patients were under 8 years old who visited 111 general hospital emergency rooms in Korea between 2007 and 2013. Results: There were 4,257 total patients enrolled in our study. The ratio of males to females was 1.11:1. The incidence of SE in Korean children was 14.5/100,000 in 2010, and the highest incidence was seen in patients 1 to 2 years old. We could not find a seasonal variation. Febrile patients with temperatures over 38 °C accounted for 1,901 patients(44.7%). Peak time on arrival was 6 p.m. to midnight for 1,301 patients (30.5%). 3,356 patients (78.8%) were admitted immediately for proper treatment, while 678 patients(15.9%) were allowed to go home after emergency treatment. Unfortunately, 4 patients (0.1%) died despite first aid. Conclusion: The most common age in SE is 1 to 2 years. Regarding the correlation of fever with SE, patients who exhibit fever accounted for almost half of the patients with SE. In our study, the mortality rate in emergency room was 0.1%. Therefore, anyone who is suspected to have SE should be immediately transferred to a general hospital with ICU facilities for intensive treatment under the direction of medical experts.

흰쥐 Kupffer 세포에 대한 Propofol의 작용

박세훈,지대림,성언기,김희선,송인환,박희영,김준수,이덕희,박대팔 대한마취과학회 2002 Korean Journal of Anesthesiology Vol.43 No.4

Background: Propofol has an antioxidant capacity and can be used for ischemia-reperfusion injury of the liver. However, the effects of propofol on the Kupffer cells have not been establisked. Methods: Kupffer cells were isolated and cultured from male Sprague-Dawley rats. The effects of propofol on the Kupffer cells were evaluated by a phagocytosis assay, TNF-α gene expression, and superoxide anion release after administering propofol in different concentrations on the cultured Kuprrer cells. Results: The latex bead phagocytosis by the Kupffer cells was suppressed when the Kupffer cells were exposed to propofol irrespective of concentrations. Higher propofol concentrations decreased the loss of Kupffer cells after latex bead phagocytosis. Propofol induced TNF-α mRNA expression in the Kupffer cells, but the mRNA expression level after 50㎍/ml of propofol decreased. The pattern of TNF-α mRNA expression induced by propofol was different to that induced by LPS: TNF-α mRNA was expressed continuously in the propofol-treated cells until 16 hours after exposure to propofol, whereas the level of TNF-α mRNA expression induced by LPS was evident after 2 hours and was not found thereafter. TNF-α production after propofol treatment was not higher than that of the control. Formazan presipitation did not show any qualitative differences between cells untreated or treated with propofol concentrations of 0.5, 5.0, and 50 ㎍/ml. Conclusions: These results showed that propofol might inhibit Kupffer cells. This suggests that propofol and be used for patients with ischemia-reperfusion injury of the liver. (Korean J Anesthesiol 2002; 43: 475~484)

동·서양 고전에 나타난 도덕적 통념에 관한 비판적 해석 -『논어』와 『에우티프론』에 나타난 아버지를 고발한 아들의 사례를 중심으로-

임명희 ( Lim Myung Hee ),김세원 ( Kim Se Won ) 동양철학연구회 2017 東洋哲學硏究 Vol.89 No.-

본 논문은 동서양의 고전 문헌에서 도덕적 통념에 관한 문제가 어떻게 다루어졌는지 고찰한 것이다. 이를 위해 『논어』에 나타난 `곧음(直)`에 관한 공자와 제자들의 대화, 『에우티프론』에 나타난 `경건함(?σιον)`에 관한 소크라테스와 에우티프론의 대화를 각각 분석하고, 그 철학적 함의를 검토하였다. 이를 통해 본 논문은, 공자와 소크라테스가 특정 도덕적 딜레마나 그것의 해결책 또는 특정 도덕관념에 대한 정의 자체에 관심이 있었다기보다, 독단적 자기 확신 또는 도덕적 통념에 관한 비판적 해석에 주안점을 두고 있었다는 것을 주장하였다. 결론적으로, 이들 철학자들은 아버지를 고발한 아들이라는 사례를 통해 우리의 삶에서 도덕적 믿음에 대한 반성적 태도가 중요함을 강조하며, 그 과정은 타자와의 대화를 수반한다는 점을 보여주고자 한 것이라 볼 수 있다. The aim of this study is to examine an issue of moral beliefs and moral conceptions in the Eastern and Western Classics. This paper focuses on the texts with one specific common material. That is the son who accused the father in the Analects(Lunyu) and the Plato`s Euthyphron. Confucius has a conversation with his follower about `Zhi(直)` and Socrates makes dialectical arguments with Euthyphron about a definition of `piety(to hosion)`. The philosophers critically examine opinions of the opposing parties to support the accusation. Other papers studied on aspects of moral dilemma(the private or the public, Physis and Nomos) or relation of religion and philosophy. But the important problem is relation between rightness(or justice) and honesty. In conclusion, this paper illuminates that the philosophers emphasize personal moral beliefs and their reflective attitudes toward one` own and lives, rather than the dilemma`s solution or the definition of moral ideas per se. Also, it is necessarily that the reflective courses involve a conversation with others.

Association between Socioeconomic Status and Altered Appearance Distress, Body Image, and Quality of Life Among Breast Cancer Patients

Chang, Oliver,Choi, Eun-Kyung,Kim, Im-Ryung,Nam, Seok-Jin,Lee, Jeong Eon,Lee, Se Kyung,Im, Young-Hyuck,Park, Yeon Hee,Cho, Juhee Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.20

Background: Breast cancer patients experience a variety of altered appearance - such as loss or disfigurement of breasts, discolored skin, and hair loss - which result in psychological distress that affect their quality of life. This study aims to evaluate the impact of socioeconomic status on the altered appearance distress, body image, and quality of life among Korean breast cancer patients. Materials and Methods: A cross-sectional survey was conducted at advocacy events held at 16 different hospitals in Korea. Subjects were eligible to participate if they were 18 years of age or older, had a histologically confirmed diagnosis of breast cancer, had no evidence of recurrence or metastasis, and had no psychological problems at the time of the survey. Employment status, marital status, education, and income were assessed for patient socioeconomic status. Altered appearance distress was measured using the NCI's cancer treatment side effects scale; body image and quality of life were measured by the EORTC QLC-C30 and BR23. Means and standard deviations of each outcome were compared by socioeconomic status and multivariate linear regression models for evaluating the association between socioeconomic status and altered appearance distress, body image, and quality of life. Results: A total of 126 breast cancer patients participated in the study; the mean age of participants was 47.7 (SD=8.4). Of the total, 83.2% were married, 85.6% received more than high school education, 35.2% were employed, and 41% had more than $3000 in monthly household income. About 46% had mastectomy, and over 30% were receiving either chemotherapy or radiation therapy at the time of the survey. With fully adjusted models, the employed patients had significantly higher altered appearance distress (1.80 vs 1.48; p<0.05) and poorer body image (36.63 vs 51.69; p<0.05) compared to the patients who were unemployed. Higher education (10.58, standard error (SE)=7.63) and family income (12.88, SE=5.08) was positively associated with better body image after adjusting for age, disease stage at diagnosis, current treatment status, and breast surgery type. Similarly, patients who were married and who had higher education had better quality of life were statistically significant in the multivariate models. Conclusions: Socioeconomic status is significantly associated with altered appearance distress, body image, and quality of life in Korean women with breast cancer. Patients who suffer from altered appearance distress or lower body image are much more likely to experience psychosocial, physical, and functional problems than women who do not, therefore health care providers should be aware of the changes and distresses that these breast cancer patients go through and provide specific information and psychosocial support to socioeconomically more vulnerable patients.

특수 언어발달 장애 환아의 임상 및음향음성학적 특성연구

김연희,박세훈,신용일,김찬양,김현기,김정수 大韓再活醫學會 2000 Annals of Rehabilitation Medicine Vol.24 No.1

한국의 대소련정책

유세희 경북대학교 평화문제연구소 1989 평화연구 Vol.14 No.-

아동의 가정내 스트레스 관리를 위한 인지·행동적 집단상담 프로그램 개발과 효과검증

박세정,박분희 한국아동교육학회 2004 아동교육 Vol.13 No.1

본 연구는 우리나라 아동들이 가정에서 겪는 스트레스를 관리할 수 있도록 돕기 위해 인지 ? 행동적 집단상담 프로그램을 개발하여 그 효과를 검증해보았다. 본 프로그램은 시작 단계와 활동 단계, 마무리 단계로 구성되었으며, 구체적으로는 8회기로 진행되었다. 내용은 도입 및 래포 형성이 1회, 부모로 인한 스트레스 내용이 3회, 형제관계로 인한 스트레스가 2회, 가정의 분위기로 인한 스트레스가 1회, 마무리가 1회로 구성되었다. 질적 분석은 아동의 가정내 스트레스 관리를 위한 인지 ? 행동적 집단상담 프로그램의 실시 과정 중 스트레스에 대한 아동들의 생각과 감정이 구체적으로 표현되었으며 스트레스에 대한 보다 많은 관심과 해결하고자 하는 아동들의 노력을 엿볼 수 있었다. 이러한 아동들의 관심과 노력, 생각, 감정들을 회기별 결과물 분석을 통해 제시하였다. The purpose of this study is to develop a cognitive- behavioral group counseling program to make children control stresses experiencing at home, and to verify the effect. The subjects of test group are 24 fifth year students from S elementary school located in Gwangju. The subjects were divided into two groups of test group and control group with 12 students each, respectively, and there was no treatment for the control group while the test group to which a 60 minute treatment of the home stress management program was applied for 8 times for 4 weeks. A quantitative and qualitative analysis was used for the data processing. SPSS win 10.0 was used for the quantitative analysis, and t-test was conducted to analyze the reduction difference of the aggression in home stress between the test and the control group. The contents were collected from each treatment based on the proceeding sequence of this program for the qualitative analysis. The results of this research are outlined as follows: First, it is found that stress degree and side effects are severely serious resulting from the investigation of cause and its side effects of child's home stress in Korea to develop the program. Second, because the retention period of child's stress is comparatively short for the adults, it is possible to cope with it in short term counseling. Third, the cognitional and behavioral group counseling program that I designed to manage child's home stress management is revealed effective for reducing the stress that may occur in the home. Fourth, group counseling for stress management shows a significant reduction especially in the physical aggression and in the linguistic aggression.

심한 척추변형(측만증 및 후만증)에 대한 척추 후방 절제술

석세일,김진혁,이상민,정의룡,이정희,김성수,정락용 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.1S

■ Purpose To report a technique of vertebral column resection through a single posterior approach and its first results in the treatment of severe spinal deformities. ■ Methods and materials Seventy spinal deformity patients treated by posterior vertebral column resection(PVCR) were reviewed. Minimum follow up was 2 years (2 - 3.3 years). There were 34 males and 36 females with a mean age of 27.4 years at the time of the operation. Etiologic diagnoses were adult scoliosis in 7, congenital kyphoscoliosis in 38, and post-infectious kyphosis in 25. The surgery consisted of temporary stabilization of the vertebral column with segmental pedicle screw fixation, resection of the vertebral column at the apex of the deformity via the posterior route followed by gradual deformity correction and global fusion. ■ Results The total number of resected vertebrae were 143; 76 in thoracic and 67 in lumbar. Mean operation time was 4 hours 31 minutes with average blood loss of 2333 ml. The deformity correction was 40o in the coronal plane and 5Oo in the sagiotal plane. Complications were encountered in 24 patients: 2 complete cord injuries in severe adult scoliosis and thoracic kyphosis patient who had significant preoperative cord compromise, 6 hematomas, 4 root injuries (all incomplete), 5 fixation failures, 2 infections and 5 hemopneumothoraxes. ■ Conclusions PVCR is an effective alternative for severe fixed spinal deformities. However, extreme caution must be taken in the patients with preoperative cord compromise who are the high risk of neurological complications.

동진강 유역 비점오염원 정밀조사

원찬희,정팔진,김민정,조선영,김세훈,김종천 전북대학교 공학연구원 ( 구 전북대학교 공업기술연구소 ) 2002 工學硏究 Vol.33 No.-

Nonpoint source pollution(NSP) arises due to agriculture activity and it is quite an extensive and complicated problem in order to control and has received a great deal of concern during the recent years, whereas point source are known to originate from an estimated volume of contaminant discharged from a distinguishable source. Extensive research work have been conducted and presented in the past with regard to the various characteristics of watershed on Dong Jin River(DJR), however there are certain drawbacks of existing survey for determining important polluting sources, distribution features of pollutants and estimated load of the organic and nutrients from the creeks. Unfortunately, investigation for loadings originating due to agricultural drainage was not satisfactory, although the regional consideration for DJR across Kim Je Field(KJF) as an agricultural area receives a reasonable source point in the agri-pollution management. Therefore it was necessary to carry out a thorough investigation into the diffuse sources resulting, to form the pollution-developing estimation and to evaluate the output roperties and determining various factors in the generation of non-point pollution. Eventually, this research work would serve as an useful tool for the development of predictive pollution management for DJR. Non-point sources in the present work were classified as municipal non-treated sewage water discharged into the river, loadings through agricultural drainages in the dry/wet field and inadequate treatment of wastewater generated from livestocks. The entire duration of the research work was from December-2001 to July-2002. Site measurement were conducted during various season, in a dry season(December), in rainfall, in seed-sowing time and also collecting data from the rural public organizations related to water management was done and examined and examined during the mid of research work. Similarly, domestic wastewater loadings due to population was based on area unit, as City, Country, Up, Myon, Dong, Ri. The Dong Jin River watershed contains small three Creeks, KoBu(KB), DongJin(DJ, including JeongEup(JE) and ChilBo(CB), WonPyong(WP). It was further divided into 32 sub-watersheds which comprises of further 5,18,9 watersheds in the creeks respectively. The results obtained from research work are presented as follows. Animal productions have marked differences in the rate of pollutant loadings reported in the following sequence: DJ(only CE)>WP>CB>KB, in a case of Korean cow and milk cow. However, it was revealed that WP creek became significantly higher than any other livestocks. According to statistical data for land use, rice field(369.0㎢) and forest(378㎢) have much occupation prior to dry paddies(125.0㎢), residential land(32.0㎢) and others(5.0㎢). Especially, rice fields receives 2.5∼3 times than dry paddies in size.

유동성 복합레진의 마모저항성에 관한 연구

윤연희,김정욱,이상훈,한세현 大韓小兒齒科學會 2002 大韓小兒齒科學會誌 Vol.29 No.2

시술시간을 줄이는데 유리한 재료인 유동성 복합레진을 유구치부에 사용하려고 고려할 때 중요한 물성 중 하나는 마모저항성이다. 이 연구의 목적은 유동성 복합레진의 마모저항성을 일반복합레진의 마모저항성을 비교하는 것이다. 실험에 사용된 유동성 복합레진으로 1군에서는 Arabesk flow (VOCO, Germany), 2군에서는 Tetric flow (Vivadent, Liechtenstein), 3군에서는 Aeliteflow (Bisco, U.S.A), 4군에서는 Filtek flow (3M Dental Co, U.S.A)을 사용하였으며 대조군으로 사용한 5군의 복합레진은 Z100 (3M Dental Co, U.S.A)이었다. 시편들(n=10)은 두께 2mm, 지름 5mm의 원통모양으로 제작하여 마모시험 전 37℃의 증류수에서 7일 동안 담가 놓았다. 제1소구치와 레진시편을 MTS 시스템에서 2Hz로 50,000회 접촉, 마모시켰다. 마모시험시 lateral excursion은 0.4mm, 교합력은 2-100N의 조건이었다. 마모시험후 마모된 부피, 최대마모깊이, 재료자체의 표면경도를 측정하였고 마모되지 않은 표면과 마모가 일어난 표면을 주사전자현미경으로 관찰하였으며 다음과 같은 결과를 얻었다. 1. 마모된 부피는 3군에서 가장 적었고 4군에서 가장 많았으며 3군<1군<2군<5군<4군의 순서로 증가하였다. 2. 3군, 1군, 2군, 5군이나 4군에 비해 통계적으로 유의하게 마모부피가 적었다(P<0.05). 그러나, 3군, 1군, 2군 사이에서와 5군, 4군 사이에서는 각각 통계적으로 유의한 차이가 없었다. 3. 최대마모깊이는 1군에서 가장 낮았고, 4군에서 가장 깊었으며 1군<3군<5군<2군<4군의 순서로 증가하였다. 4. 5군의 표면경도는 다른 유동성 복합레진군에 비해 통계적으로 유의하게 높았으나(P<0.05). 마모부피나 최대마모깊이와는 통계적으로 유의한 상관관계를 보이지 않았다. 5. 마모되지 않은 표면과 마모가 일어난 표면을 주사전자현미경으로 관찰한 결과, 유동성 복합레진군과 5군 사이에 마모양상이 다르게 나타나는 것을 볼 수 있었다. When we use the flowable resin on the primary molars for quick handling, one of the most important property is the wear resistance. This study was performed to compare the wear resistance characteristics of four flowable composite resins [Arabesk flow (group 1), Tetric flow (group 2), Aeliteflow (group 3), Filtek flow (group 4)] to that of one control composite resin [Z100 (group 5)]. Specimen discs(n=10), 10mm wide and 2mm thick, were stored in distilled water at 37℃ for 7 days prior to testing. The specimens were subjected to 50,000 strokes at 2Hz on the MTS system. During the test, the following parameters were maintained: the ;atera; excursion at 0.4mm, occlusal force at 2-100N with a force profile in the form of a half sine wave. The measurements of volume loss, depth of wear, and Vicker's hardness number of composite resins, and SEM obserbations of the polished and abraded surfaces were established. One-way ANOVA and Scheffe's multi-ple comparison test were employed to detect statistically significant differences among the flowable composite resin group and the control composite group at P<.05. The following results were obtained: 1. Group 3 showed the least volume loss, while group 4 showed the greatest. The mean volume loss increased in the following order: group 3<group 1<group 2<group 5<group 4. 2. Group 3, group 1, and group 2 showed significantly lesser volume loss compared to group 5 and group 4(p<0.05). However, There was no statistically significant difference among group 3, group 1 and group 2. There was no statistically significant difference between group 5 and group 4. 3. Group 1 showed the shallowest depth of wear, while group 4 showed the deepest. The mean depth of wear increased in the following order: group 1<group 3<group 5<group 2<group 4. 4. Group 5 showed significantly highest hardness value compared to the flowable composite resin groups(p<0.05), but there was no correlation between wear resistance and Vickers hardness number. 5. SEM observation of the unworn and worn surfaces revealed the differences in the wear appearance between the flowable composite resin groups and the control.