Gegenwartserkenntnis , Zukunftshoffnung und Parteilichkeit bei Droysen , J . G .

이상신 고대사학회 1976 사총 Vol.20 No.-

Galvanic Mucositis Occurred at Leukoedema of Bilateral Buccal Mucosa

이상신,김철,김성훈,이석근 대한구강악안면병리학회 2014 대한구강악안면병리학회지 Vol.38 No.4

Oral galvanism is known to induce chronic irritation on oral mucosa, but the related pathology rarely occurs. A 65 years old malecomplained of linear horizontal ulcerations on his bilateral buccal mucosa for one month. The oral ulcerations were parallel and approximatedto his occlusal plane. He had multiple metallic crowns using gold and nickel cobalt alloy at bilateral upper and lower molarteeth, and also had accustomed to heavy smoking for more than twenty years. Biopsy examination was performed with immunohistochemicalstaining using antisera of PCNA, D2-40, and PARP. The epithelial ulcer had clear margin and was replaced bygranulation tissue containing many dilated lymphatic vessels, which were positive for D2-40, but showed no feature of pseudo-necroticmembrane. Nearby epithelium showed the typical features of leukoedema, characterized by edematous keratinocytes with clear cytoplasmsand pyknotic nuclei, low rete ridges, and rough superficial epithelial layer, where PCNA was rarely positive. Some superficialedematous keratinocytes showed perinuclear cytoplasmic vacuolization, and their peripheral nuclear chromatins were positive for PARP. Taken together, the present mucosa ulceration was different from aphthous stomatitis, herpes stomititis, oral lichen planus, etc., thusit was postulated that the galvanic current generated from between the upper and lower dissimilar metal crowns could affect the precedentleukoedema caused by heavy smoking habit and produce the linear horizontal buccal ulceration. Therefore, the present case was diagnosedas galvanic mucositis associated with leukoedema, and it was also hypothesized that the mild and persistent galvanic currentwas able to deplete the cytoplasmic fluid of leukoedema keratinocytes via the osmotic pressure difference elicited by increased ionicconcentration of galvanism, and followed by severe keratinocyte apoptosis and oral mucosa ulceration.

A case of Caliber Persistent Artery in Retromolar Buccal Mucosa Exhibiting Slow Growing Potential

이상신,최상훈,최우혁,김연숙,이석근 대한구강악안면병리학회 2015 대한구강악안면병리학회지 Vol.39 No.3

Caliber persistent artery (CPA) is a vascular anomaly presenting as a bluish and pulsatile artery in the subepithelial tissue. Although the incidence of CPA was debated, many CPAs occurred in the perioral and facial tissues at which the embryonal strapedial artery networks were distributed. The present study demonstrated a case of CPA occurred in the retromolar buccal mucosa in a 37 years old male. The lesion showed many pinkish granular spots, but was asymptomatic except biting irritation during mastication. It had slowly increased in size up to 20 × 25 mm for 3 years, and recently became hemorrhagic due to the biting injury between left upper and lower second molars. With the fear of oral cancer an incisional biopsy was performed, and followed by histological and immunohistochemical study. Histologically the lesion showed many tortuous artery localized at the submucosa area, and the arterial wall was thick and its lumen was narrowed and shrunken. In the immunochemistry α-SMA was positive for thick smooth muscle layer of artery and arterioles, TGase 2 was weakly positive for the luminal surface of arterial intima, and bFGF was consistently positive for the perivascular fibrous tissue. But PCNA, VEGF, CD31, CMG2, TGF-β1, HSP-70, and 14-3-3 were almost negative for the vascular tissue. Therefore, it was presumed that the lesion was not actively proliferative nor degenerative but still retained its cellular stability and slow growing potential. It was finally diagnosed as CPA differentially from arterio-venous malformation, hemangioma, lymphangioma, and squamous cell carcinoma. The retromolar buccal mucosa CPA is first reported in this study and may present usual clinical findings depending on its size and location. This asymptomatic lesion could be severely hemorrhagic by minor biting injury, therefore, precise differential diagnosis should be made through biopsy, and careful therapy be followed.

Differential Diagnosis of Papillary Papilloma, Verrucous Papilloma, and Inverted Papilloma from Oral Squamous Cell Papillomas

이상신,김현주,박성연,김연숙,이석근 대한구강악안면병리학회 2012 대한구강악안면병리학회지 Vol.36 No.2

Oral squamous cell papillomas(OSCPs) showed various features in their etiology, histology, and prognosis. Therefore, it is necessary to diagnose differentially according to their pathological examinations. In the present study total 14 cases of OSCPs were evaluated and characterized to be three types of OSCPs, i.e., papillary papilloma, verrucous papilloma, and inverted papilloma. The present study demonstrated that among 14 cases of OSCPs papillary papilloma (n=6) showed the typical papillary projection of squamous epithelium with severe acanthosis of upper spinous layer cells, accompanying frequent nuclear vacuolization. And verrucous papilloma (n=7) showed the diffuse acanthosis of whole spinous layer cells with severe basal hyperplasia, resulted in the thick squamous epithelium exhibiting verrucous surface and irregularly ingrowing rete pegs. One case of inverted papilloma showed the typical ingrowth of basal layer cells deeply into underlying connective tissue, resulted in the formation of multiple fissures on the surface area. The present study also revealed the predominant nuclear vacuolization suspicious for viral infection in papillary papilloma, and also heavy smoking history in the verrucous papilloma. On the other hand, as the epithelium of inverted papilloma ingrew into the underlying deep connective tissue up to the muscular layer, it is supposed that the inverted papilloma has a potential of basal layer proliferation strong enough to invade the protecting barrier of underlying connective tissue, or that the underlying connective tissue was too weak to prevent the ingrowth of basal layer epithelium. Taken together, because the OSCPs show heterogenous origins and variable pathological prognosis, it is suggested that the OSCPs should be differentially diagnosed at least into three types, i.e., papillary papilloma, verrucous papilloma, and inverted papilloma.

방언에서의 자매어들의 대립성 현현(顯現) 양상 연구 - 접두사 ‘참-’에 의한 파생어를 중심으로

이상신 국어학회 2022 국어학 Vol.- No.103

본고는 방언에서 ‘참’에 의한 어휘의 대립을 관찰하여 자매 관계에 있는 어휘들이 대립 관계를 드러내기 위해 구별 표지를 어떻게 이용하는지를 논의하고자 하였다. 우선, ‘참’이나 ‘들’ 둘 중 하나만으로도 ‘참깨’와 ‘들깨’가 구분될 수 있음에도 둘 모두가 함께 쓰이고 있는 이유를 살펴보고자 하였고, 다음으로, ‘참깨:들깨’에서 ‘참’ 및 ‘들’이 함께 쓰이는 것과 달리 ‘참외:오이’ 및 ‘외:물외’에서는 ‘참’과 ‘물’이 홀로 그리고 배타적으로 쓰이는 이유를 살펴보고자 하였다. 논의의 결과는 같다. 첫째, ‘참깨:들깨’의 대립에서 구별 표지 ‘참’과 ‘들’이 함께 쓰이는 것은 ‘들깨’의 ‘들’이 “野”의 뜻을 가지고 있지 않기 때문이다. 둘째, ‘참깨:들깨’의 대립을 보이기 전에 일시적으로 ‘깨:들깨’의 시기가 있었다. 셋째, ‘참깨:들깨’의 대립과는 달리 ‘참외:오이’와 ‘외:물외’의 대립에서 구별 표지 ‘참’과 ‘들’이 배타적으로 쓰이는 것은 ‘참’과 ‘들’의 의미적 투명성 때문이다. 넷째, ‘참외:오이’의 대립과 ‘외:물외’의 대립은 그 역사가 오래인데, 기원적으로 “참외”와 “오이”가 구별되지 않은 채 ‘외’로만 쓰이다가 경기도를 중심으로 한 중앙방언에서는 구별 표지 ‘참’을 이용하고 그 외곽 지역에서는 구별 표지 ‘물’을 이용하여 “참외”와 “오이”를 구별하게 된 결과가 현대 중앙방언의 ‘참외:오이’의 대립과 중앙방언 외곽 남한 방언의 ‘외:물외’의 대립이다.

다중센서를 이용한 무선센서네트워크시스템에서의 효율적인 측정데이터 신뢰성 향상 방법

이상신,송민환,원광호,김중환 한국정보통신설비학회 2009 정보통신설비학회논문지 Vol.8 No.3

유방암 수술환자의 디스트레스 및 연관인자 : 단면연구

이상신,임효덕,우정민 한국정신신체의학회 2018 정신신체의학 Vol.26 No.2

Objectives:This study aimed to investigate the level of distress using the distress thermometer (DT) and the factors associated with distress in postoperative breast cancer (BC) patients. Methods:DT and WHOQOL-BREF (World Health Organization Quality of Life Scale Abbreviated Version) along with sociodemographic variables were assessed in patients undergoing surgery for their first treatment of BC within one week postoperatively. The distress group consisted of participants with a DT score ≥4. The prevalence and associative factors of distress were examined by descriptive, univariable, and logistic regression analysis. Results:Three hundred seven women were recruited, and 264 subjects were finally analyzed. A total of 173 (65.5%) were classified into the distress group. The distress group showed significantly younger age (p=0.045), living without a spouse (p=0.032), and worse quality of life (QOL) as measured by overall QOL (p=0.009), general health (p=0.005), physical health domain (p<0.000), and psychological health domain (p=0.002). The logistic regression analysis showed that patients aged 40-49 years were more likely to experience distress than those aged ≥60 years (Odds ratios [OR]=2.992, 95% confidence interval [CI] 1.241-7.215). Moreover, the WHOQOL-BREF physical health domain was a predictive factor of distress (OR=0.777, 95% CI 0.692-0.873). Conclusions:A substantial proportion of patients are experiencing significant distress after BC surgery. It would be expected that distress management, especially in the middle-aged patients and in the domain of physical QOL (e.g., pain, insomnia, fatigue), from the early BC treatment stage might reduce chronic distress. KEY WORDS : Breast cancer ㆍPsycho-oncology ㆍDistress ㆍDistress thermometer ㆍQuality of life. 연구목적: 유방암 환자가 치료 초기에 경험하는 디스트레스는 유방암 생존기까지 지속되는 만성 디스트레스의 위험요소로 알려져 있다. 본 연구는 유방암 첫 치료로써 수술을 받은 환자를 대상으로 디스트레스 온도계(distress thermometer, DT)를 이용하여 디스트레스의 정도와 이와 연관된 인자를 조사하는 것이다. 방 법: 2013년 4월 1일부터 2017년 3월 31일 사이에 경북대학교병원에서 유방암 첫 치료로써 수술을 받고 일주일이내에 있는 환자를 대상으로 하였다. DT로 디스트레스의 정도를 측정하였고 한국판 세계보건기구 삶의 질척도 단축형(Korean version of the World Health Oganization Quality of Life Scale Abbreviated Version, WHOQOL-BREF)으로 삶의 질을 측정하였다. 그 외 기본 인구학적 자료, 암 및 암 치료 관련 자료를 수집하였다. DT 점수 4점 이상인 대상자를 디스트레스 군으로 분류하였다. 디스트레군과 연관된 인자를 알기 위하여디스트레스군과 비-디스트레스 군 사이의 변수 차이를 단변수 분석(univariable analysis) 하였다. 로지스틱 회귀분석을 시행하여 디스트레스 군을 예측할 수 있는 인자를 조사하였다. 결 과: 대상자는 총 307명이었다. 이 중에서 DT에 응답하지 않은 39명, WHOQOL-BREF에서 6개 항목 이상 답을하지 않아서 채점을 할 수 없었던 4명을 제외한 264명이 분석 대상자였다. 65.5%(n=173)가 디스트레스 군으로분류되었다. 단변수 분석(univariable analysis)에서 디스트레스 군이 비-디스트레스 군과 비교하여 더 젊었으며(p=0.045), 배우자와 동거하지 않는 경우가 더 많았다(p=0.032). 삶의 질 영역에서 디스트레스 군이 전반적삶의 질(p=0.009), 전반적 건강상태(p=0.005), 신체건강영역 p<0.001), 심리건강영역(p=0.002)에서 더 나쁜 삶의 질을 보였다. 로지스틱 회귀분석에서 60세 이상의 환자에 비하여 40-49세의 환자가 디스트레스에 이환 될확률이 약 3배 높았고[OR=2.992, 95% confidence intervals (CI) 1.241-7.215], WHOQOL-BREF영역 중 신체건강영역이 디스트레스를 예측할 수 있는 인자로 나타났다(OR=0.777, 95% CI 0.692-0.873). 결 론: 유방암 수술 치료 초기단계에서부터 상당한 수의 환자가 유의한 수준의 디스트레스를 경험하고 있다. 특히생산성이 왕성한 삶의 주기에 있는 40대의 환자가 60대 이상의 환자에 비하여 수술 후 일주일 이내에 겪는 심리적 고통이 심할 가능성이 높다. 이러한 환자들에게서 수술 초기부터 신체적 삶의 질과 연관된 영역(예 : 통증, 불면, 피로 등)에 대해 평가하고 개입하는 것이 디스트레스 수준을 경감시킬 가능성이 있다. 중심 단어:유방암·정신종양학·디스트레스·디스트레스 온도계·삶의 질.

An experimental study on the structural alteration of C3H8-air premixed flame affected by ultrasonic standing waves of various frequencies

이상신,김정수,김희동 대한기계학회 2015 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.29 No.3

This experimental study scrutinizes the structural variation of a premixed propane-air flame according to the frequency change of ultrasonicstanding waves (USWs) at various equivalence ratios. Visualization technique via Schlieren photography is employed in theobservation of the flame structure and in the analysis of the flame velocities along the propagation. A distorted flame front and horizontalsplitting in the burnt zone result from the USW. The vertical locations of the distortion and horizontal stripes are closely dependent on thefrequency of the USW. In addition, the propagation velocity of the flame front floored by the standing wave is greater than that in thecase without the excitation by the standing wave. As expected, the influence of the USW on the premixed-flame propagation becomesprominent as the frequency increases. The results suggest that a well-defined USW may be applied to combustion devices, such as gasturbines and chemical rocket engines, to achieve an active control of the instability that frequently intervenes in such systems.

‘운동감각적 인지(kinesthetic cognition)’ 기반 ‘표현 움직임(expressive movement)’을 활용한 극화 교수⋅학습 방법 탐색 - 2015 초등 전 학년 국어 교과서 수록 극화 활동을 중심으로 -

이상신 한국초등국어교육학회 2019 한국초등국어교육 Vol.67 No.-

There are inseparable relations among the “body,” “mind” and “environment” from the perspective of phenomenology of perception, which states that “The subject of perception is the body.” In Korean lessons around the “mind” mechanism such as “estimating the mind” of a character, activities based on the idea of “separation between the body and the mind” will thus serve as obstacles to the cultivation of learning experiences to a significant level. Noticing this, the present study devised a teaching and learning model for dramatic activities using “expressive movement” based on “kinesthetic cognition” and analyzed precisely the educational content of dramatic activities in the elementary Korean textbooks throughout the six grades. Based on the findings, the study proposed some future directing points for dramatic learning as alternatives. The findings provided the following implications: first, if a dramatic teaching and learning process is designed around “expressive movement” based on “kinesthetic cognition,” a dynamic atmosphere will be created for assessment to achieve unification between goals and evaluations; second, introspective “mind reading” in “performance⇄observation” based on “intention of expression” and “reading of expression” will serve as a catalyst for dramatic activities to settle down as learning experiences conducive to growth and development; third, the level of learning experiences, which remains at the proximal development level, will move forward to the practice stage of “potential level” at last in the formation process of introspective “mind” among “performance⇄observation” learners to organize their stories based on their narrative imagination and cognition; and finally, there is a need for overall re-reviews of the target grades and educational content in education connecting kindergarten and elementary school, which is currently limited to kindergarten children and first graders. ‘지각의 주체는 몸’이라는 지각 현상학적 관점에서 보면 ‘몸’과 ‘마음’과 ‘환경’은 불 가분리의 관계로 존재한다. 따라서 인물의 ‘마음 짐작하기’ 등과 같은 ‘마음’ 기제 중심 의 국어과 수업에서 ‘몸 따로 마음 따로’ 식의 활동은 학습 경험을 유의미한 수준으로 함양하는 데 걸림돌로 작용하기 마련이다. 이 점에 착안하여 본 연구에서는 <‘운동감각 적 인지’ 기반 ‘표현 움직임’을 활용한 극화 학습의 교수⋅학습 모형>을 구안하고 이를 바탕으로 초등 전 학년 국어 교과서에 수록된 극화 활동의 교육 내용을 정밀 분석하였다. 그리고 그 결과를 토대로 극화 학습의 향후 지향점을 대안 마련의 차원에서 제안하였다. 연구 결과 다음과 같은 시사점을 얻을 수 있었다.: 첫째, ‘운동감각적 인지’ 기반의 ‘표현 움직임’을 중심으로 극화 교수⋅학습 과정을 설계할 경우 목표와 평가의 일체화 를 실현할 수 있는 역동적 평가 분위기가 조성된다. 둘째, ‘표현 의도’와 ‘표현 읽기’에 기반한 ‘수행⇄관찰’의 자기 성찰적 ‘마음 읽기’는 극화 활동이 성장과 발달을 돕는 학 습 경험으로 자리잡게 하는 데 기폭제 역할을 한다. 셋째, 서사적 상상과 서사적 인지에 기반을 두고 자신의 이야기를 구성해 나가는 ‘수행⇄관찰’ 학습자의 자기 성찰적 ‘마음’ 형성의 과정에서 근접발달수준에 머물러 있던 학습경험의 수준이 비로소 ‘잠재적 수준’ 의 실천 단계로 거듭나게 된다. 넷째, ‘유치원-초등 1 학년’에 한정돼 있는 유⋅초 연계 교육의 대상 학년과 교육 내용에 대한 전반적 재검토가 필요하다.

이옥이 기록한 18∼19세기 국어에 대한 연구

이상신 한국현대문학회 2012 한국현대문학회 학술발표회자료집 Vol.2012 No.8