유두상 혈관내막 증식증의 임상적 보고

이정우,정호윤,이석종,김귀락,최강영,양정덕,조병채,Lee, Jeong-Woo,Chung, Ho-Yun,Lee, Seok-Jong,Kim, Gui-Rak,Choi, Kang-Young,Yang, Jung-Dug,Cho, Byung-Chae 대한성형외과학회 2010 Archives of Plastic Surgery Vol.37 No.3

Purpose: Intravascular papillary endothelial hyperplasia (IPEH), also known as Masson's pseudoangiosarcoma, is a rare disease which is now considered as a reactive process of the endothelium rather than a benign neoplasm. It can occur in any blood vessels in the body but more common in the head and neck region as a solitary, often tender, bluish or reddish nodule. IPEH is characterized by the development of endothelial-lined papillary projections in a vascular lumen, usually associated with thrombotic material, the endothelial cells in the papillary structures showing only slight atypia and occasional mitotic Figures, the absence of tissue necrosis. Methods: 8 patients with IPEH were enrolled in the study from 2002 to 2007. All 8 lesions were surgically excised for histopathologic diagnosis. Results: 4 patients were female. The duration of the lesions ranged from 3 months to 15 years. The tumors were first noted between the ages of 20 and 72 years. 4 patients had lesions on the head; 2 on the toe; 1 on the back; and 1 on the finger, respectively. All lesions were solitary, ranged in size from 2 mm to 27 mm. There were no recurrences. Conclusion: The clinical appearance of IPEH is not specific, presented as a primary neoplasm, and the diagnosis can be established by microscopic examination. Complete surgical excision is the best choice of therapy for patients with IPEH, and is both diagnostic and curative. Awareness of this lesion will prevent incorrect diagnosis and overly aggressive treatment.

세기변조방사선치료 선량분포 확인을 위한 2차원적 이온전리함 배열의 특성분석

이정우,홍세미,김연래,최경식,정진범,이두현,서태석,Lee, Jeong-Woo,Hong, Se-Mie,Kim, Yon-Lae,Choi, Kyoung-Sik,Jung, Jin-Beom,Lee, Doo-Hyun,Suh, Tae-Suk 한국의학물리학회 2006 의학물리 Vol.17 No.3

본 연구의 목적은 2차원적 이온전리함 배열의 특성을 분석하고 세기변조방사선치료 선량분포 확인의 유용성을 평가하기 위함이다. 본 실험에 사용된 2차원적 이온전리함 배열(MatriXX, Scanditronix-Wellhofer, IBA, Germany)은 $24{\times}24cm^2$ 범위에 1,024개의 평판형 전리함(용적: $0.08cm^3$, 직경: 4.5 mm, 높이: 5 mm, 배열간격: 7.62 mm)이 일정한 간격으로 배열되어있다. MatriXX의 특성분석을 위해 선량 직선성, 선량률 의존도, 출력 계수, 단기 선릉재현성을 분석하였으며, 선량분포 확인의 신뢰도를 평가하기 위해 Varian사의 동적쐐기와 세기변조 방사선치료의 선량분포를 분석하였다. 선량 직선성의 범위는 $1{\sim}800$cGy이었으며, 1% 미만의 오차율을 보였다. 선량률 의존성(범위 $100{\sim}600MU/min$)은 300 Mu/min을 기준으로 했을 때 모든 선량률 범위에서 0.4% 미만의 선량변화를 보였다. 또한, 물팬톰에서 0.1 cc 지두형 전리함으로 측정한 출력계수와 폴리스틸렌 팬톰에서 MatriXX로 측정한 출력계수를 비교하였다. 이 실험의 결과, $3{\times}3{\sim}24{\times}24cm^2$ 범위에서 0.5% 미만의 일치를 나타내었다. 단기 출력재현성 확인을 위하여 15분 간격으로 6회 측정한 결과, 0.5% 내의 차이를 보였다. 동적쐐기와 세기변조 방사선 조사면의 일치성 실험에서도 치료계획장치의 계산값과 필름측정값이 비교적 잘 일치함을 알 수 있었다. 본 연구를 통해 MatriXX의 물리적인 특성을 분석하였으며 세기변조방사선치료의 품질관리를 위한 유용성을 확인하였다. A commercial ion chamber matrix was examined the characteristics and its performance for radiotherapy qualify assurance. The device was the I'mRT 2D-MatriXX (Scanditronix-Wellhofer, Schwarzenbruck, Germany). The 2D-MatriXX device consists of a 1020 vented ion chamber array, arranged in $24{\times}24cm^2$ matrix. Each ion chamber has a volume of $0.08cm^3$, spacing of 0.762 cm and minimum sampling time of 20 ms. For the investigation of the characteristics, dose linearity, output factor, short-term reproducibility and dose rate dependency were tested. In the testing of dose linearity. It has shown a good signal linearity within 1% in the range of $1{\sim}800$cGy. Dose rate dependency was found to be lower than 0.4% (Range: 100-600 Mu/min) relative to a dose rate of 300 Mu/min as a reference. Output factors matched very well within 0.5% compared with commissioned beam data using a ionization chamber (CC01, Scanditronix-Wellhofer, Schwarzenbruck, Germany) in the range of field sizes $3{\times}3{\sim}24{\times}24cm^2$. Short-term reproducibility (6 times with a interval of 15 minute) was also shown a good agreement within 0.5%, when the temperature and the pressure were corrected by each time of measurement. in addition, we compared enhanced dynamic wedge (EDW, Varian, Palo Alto, USA) profiles from calculated values in the radiation planning system with those from measurements of the MatriXX. Furthermore, anon-uniform IMRT dose fluence was tested. All the comparison studies have shown good agreements. In this study, the MatriXX was evaluated as a reliable dosimeter, and it could be used as a simplistic and convenient tool for radiotherapy qualify assurance.

Comparison of Enhanced Dynamic Wedge with Physical Metal Wedge based on the Basic Dosimetric Parameters

이정우,홍세미,최경식,정진범,최보영,장홍석,서태석,Lee Jeong-Woo,Hong Semie,Choi Kyoung-Sik,Chung Jin-Beom,Choe Bo-Young,Jang Hong Seok,Suh Tae-Suk Korean Society of Medical Physics 2005 의학물리 Vol.16 No.2

기능강화동적쐐기는 쐐기 형태의 선량 분포를 만드는 방법과 선량 특성적인 면에서 금속쐐기와 상당한 차이를 가지고 있다. 기능강화동적쐐기의 임상적용을 위해서는 금속쐐기와 다른 선량특성을 분석하고 이에 따른 적절한 커미셔닝이 필수적이다. 본 연구의 목적은 기본 선량계측인자에 기초한 기능강화동적래기와 금속쐐기의 선량특성을 분석하는 데 있다 선량 계측학적 특성을 나타내는 심부선량분포, 조사면 주변 선량, 표면선량, 실효 쐐기인자, 쐐기의 선량측면도를 측정, 분석하였다. 또한 열린 조사면과 금속쐐기와의 비교측정을 통해 기능강화동적쐐기가 가지고 있는 고유한 특성을 분석하였다. 기능강화동적쐐기의 선량측면도 측정은 Chamber Array 24 (CP24)를 이용하였으며, Golden Segmented Treatment Table (Golden-577)로 구현한 치료 계획 장치의 계산 값과 비교하였다. 또한 실호쐐기인자 측정은 각각의 X, Y 콜리메이터에 따른 특성을 분석하였다. 심부 선량 백분율측정에서 열린 조사면과 기능강화쐐기의 비교결과, $0.2\~0.5\%$ 이내로 일치하였고, 금속 쐐기인 경우 약 $2\%$의 비교적 큰 차이를 보였다. 조사면 주변선량측정에서는 금속쐐기가 약 $1\%$ 높았다. 표면선량 측정 결과, 금속쐐기가 약 $10\%$ 낮게 평가되었다 기능강화쐐기의 실효쐐기인자는 Y jaw가 커짐에 따라 연속적으로 감소됨을 알 수 있었다. X jaw에 따른 쐐기인자 의존도 측정에서는 X jaw에 따른 의존도는 거의 없는 것으로 평가되었다. 또한 비대칭 조사면의 쐐기 인자측정에서는 비대칭에 상관없이 Y jaw의 크기만 같으면 실효쐐기인자가 같았다. 선량측면도 측정에서는 CA24를 이용해 얻은 실측값과 Golden STT로 Cadplan에서 구현한 계산 값이 $1\%$이내로 일치하였다. 본 연구를 통해 기능강화동적쐐기가 가지고 있는 특성을 분석하였으며, 금속쐐기를 대체할 수 있는 유용한 도구임을 알 수 있었다. For clinical implementation of Enhanced Dynamic Wedge (EDW), it is necessary to adequately analyze and commission its dosimetric properties in comparison to common physical metal wedge (MTW). This study was implemented with the essential measurements of parameters for clinical application, such as percentage depth dose, peripheral dose, surface dose, effective wedge factor, and wedge profile. In addition, through the comparison study of EDW with open and MTW, the analysis was performed to characterize the EDW. We also compared EDW dose profiles of measured values using chamber array 24 (CA24) with calculated values using radiation treatment planning system. PDDs of EDW showed good agreements between $0.2\~0.5\%$ of open beam, but $2\%$ differences with MTW. In the result of the measurements of peripheral dose, it was shown that MTW was about $1\%$ higher than open field and EDW. The surface doses of $60^{\circ}$ MTW showed 10% lower than the others. We found that effective wedge factor of EDW had linear relationships according to Y jaw sizes and was independent of X jaw sizes and was independent of X jaw sizes and asymmetric Y jaw opening. In comparison with measured values and calculate values from Golden-STT based radiation treatment planning system (RTP system), it showed very good agreement within difference of $1\%$. It could be concluded that EDW is a very reliable and useful tool as a beam modification substitute for conventional MTW.

개인 트레이의 설계와 인상채득방법이 의치 변연의 형태에 미치는 영향에 관한 연구

이정우,오상천,진태호,Lee, Jeong-Woo,Oh, Sang-Chun,Jin, Tai-Ho 대한치과보철학회 1995 대한치과보철학회지 Vol.33 No.1

The purpose of this study is to inquire about the effects of individual tray design and impression method on the border extension and contour of denture. 10 students at the dentistry college who have normal occlusion and symmetric facial form and normal facial muscle activity were selected. The tray was designed three types (large, medium, small tray). After border molding was done by dentist and operator, final impression was taken. The length of impression body and width of border were measured by a vernier caliper on the cast. The obtained results were as follows : 1. As the tray border was shortened, the length of impression body and width of border was short (P<0.01). 2. When the impression was taken with the small tray, the length of impression body was short in passive border molding than active border molding. 3. When the medium tray was used, the width of impression body was short in passive border molding than active border molding.

아동기 자녀의 환경에 대한 관심과 보전행동에 관한 연구

이정우,황경혜 ( Jeong Woo Lee,Kyung Hae Hwang ) 대한가정학회 1998 Family and Environment Research Vol.36 No.5

과다 유두(Supernumerary Nipple) 2례

이정우,양정덕,이정훈,최강영,김귀락,정호윤,조병채,Lee, Jeong-Woo,Yang, Jung-Dug,Lee, Jung-Hun,Choi, Kang-Young,Kim, Gui-Rak,Chung, Ho-Yun,Cho, Byung-Chae 대한성형외과학회 2010 Archives of Plastic Surgery Vol.37 No.5

Purpose: Supernumerary nipple or polythelia is one of the developmental anomalies occurring at the embryonic stage and this anomaly usually arises from the milk line. While this atypical feature is determined during early developmental stage, it may not come out obviously or become troublesome until puberty or lactation. Moreover, sometimes it is confused with a pigmented nevus. Methods: Case 1, a 18-year-old woman with intramammary supernumerary breast consisted of another nipple with middle sized areola on the right lower breast was admitted for a $2.8{\times}3.1\;cm$-sized mass on the right breast which was starting appeared 1 year earlier. The preliminary cytological examination of the material obtained by needle aspiration biopsy from the mass was revealed by fibroadenoma with no malignant change. The patient had the surgical excision of the mass and accessory breast. Case 2, a 16 year-old woman admitted for intra-areolar polythelia of the left breast, even she doesn't have any family history of polythelia. Since she wanted surgical correction of her atypical nipple for aesthetic and psychological reasons, we reconstructed the areola using transposition flaps in an S-plasty design. Results: Case 1, the excised supernumerary nipple showed following histological features. In the superficial layer, an acanthotic and hyperpigmented epithelium with elongated rete ridges was found. In the dermis, there were follicles with hairs surrounded by hypertrophic sebaceous glands. In the deepest portion, abundant secretory glomerules and excretory ducts of apocrine gland type were observed. Case 2, follow-up visits 3 months after the procedure showed a satisfactory result with good shape and projection of the nipple. Conclusion: We report two cases of aberrant mammary tissue who underwent surgical correction, including complete breast (with nipple, areola, and glandular tissue) and intra-areolar polythelia according to the Kajava's classification, and the results were satisfactory.

논문편 : 신세대 기혼남녀의 라이프스타일 및 가정경영의식

이정우,김명자,계선자,박미석,지금수,김경숙,이정숙,박미금 ( Jeong Woo Lee,Myung Cha Kim,Sun Ja Kye,Mee Sok Park,Keum Soo Chi,Kyung Sook Kim,Jung Sook Lee,Mi Kum Park ) 대한가정학회 1996 Human Ecology Research(HER) Vol.34 No.6

확장된 쐐기조사야에 의한 조직산란계수의 변화

이정우,조화섭,박성렬,Lee, Jeong-Woo,Cho, Hwa-Seop,Park, Seong-Ryul 대한방사선치료학회 1998 大韓放射線治療技術學會誌 Vol.10 No.1

In recent days, although many kinds of beam modifiers are developing and using for clinical purposes in accordance with progressing medical engineering, physical wedges are preferred to use as a beam modifier by a lot of institutions until now because of cost, complexities of dosimetry and mechanical uncertainties. According to progressing technology, available field size of wedge is more enlarger than that of old model LINAC. Because field size dependence of wedged fields increases in new model LINAC, we was trying to know that how much different PSFs are in enlarged wedged fields compared with open fields. In small or middle size of fields($4{\times}4{\sim}15{\times}15cm$), there are only a few percents of PSF variation between open and wedged fields. But there are $2{\sim}8\%\;variations\;in\;relatively\;large\;fields(20{\times}20{\sim}30{\times}40cm)$.

반도체 capacitive 지문 센서 및 이미지 합성 방법

이정우,민동진,김원찬,Lee, Jeong-Woo,Min, Dong-Jin,Kim, Won-Chan 대한전자공학회 1999 電子工學會論文誌, D Vol.d36 No.2

본 논문에서는 저 비용, 고해상도 반도체 지문 센서칩에 대하여 논한다. 제작된 테스트 칩은 $64{\times}256$ 센싱 셀(sensing cell)로 구성되어 있으며, 칩의 크기는 $2.7mm{\times}10.8mm$이다. sensing cell 내부에서 일어나는 전하 재분포를 감지하는 새로운 방식을 이용하여 내부의 기생 캐패시턴스의 영향을 효과적으로 제거하는 방법을 제안하였다. 제안하는 방법은 센싱 셀의 감지 능력을 키우므로 센싱 셀의 크기를 줄일 수 있고, 따라서 고해상도의 이미지를 추출할 수 있다. 표준 0.6${\mu}m$ CMOS 공정을 이용하여 제작된 칩은 600dpi의 해상도를 가지는 지문 이미지를 추출한다. 제조 단가를 낮추기 위하여 지문의 부분 이미지들로부터 전체 지문 이미지를 얻어내는 이미지 합성 방법의 가능성과 문제점에 대해서도 논의하였다. This paper introduces a possibility of a low-cost, high-resolution fingerprint sensor chip. The test chip is composed of $64{\times}256$ sensing cells(chip size : $2.7mm{\times}10.8mm$). A new detection circuit of charge sharing is proposed, which eliminates the influences of internal parasitic copacitances. This the reduced sensing-capacitor size enables a high resolution of 600dpi, using even conventional 0.6${\mu}m$ CMOS process. The partial fingerprint image captured therefrom are synthesized into a full fingerprint image with a image synthesis algorithm. The problems and possibilities of image synthesis technique are also analyzed and discussed.

자외선 조사로 유발된 피부 염증성 반응에 맥동성 초음파가 미치는 영향

이정우,박수지,윤세원,Lee, Jeong-Woo,Park, Su-Ji,Yoon, Se-Won 대한물리치료학회 2011 대한물리치료학회지 Vol.23 No.4

Purpose: This study aims to examine the effects of pulsed ultrasound on skin inflammatory reaction induced by ultraviolet irradiation. Methods: Twenty subjects were selected for this study. Inflammatory reaction was induced by ultraviolet irradiation in two areas of the lumbar region of the subjects. Pulsed ultrasound (3 MHz) was applied to one of the two areas of inflammatory reaction at a pulse ratio of 1:4, intensity of $0.5W/cm^2$, once a day for 5 min, and pulsed ultrasound was not applied to the other area. Wound color (chromatic red), luminance (gray) and wound contraction (area) were measured using digital imaging processing method. Results: There was a significant difference in wound color (chromatic red) in the interaction between time and area. There was a significant difference in luminance in the interaction between time and area. There was a significant difference in wound contraction between the two areas. Conclusion: These results indicate that pulsed ultrasound increased the wound contraction rate and reduced the inflammatory reaction activity such as erythema induced by ultraviolet irradiation.