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도시재생을 위한 체험기반 컬처노믹스 실행에 관한 보고 - 서울로7017의 액티베이터(Activator) -
이혜수,정진도 한국일러스트레이션학회 2018 일러스트레이션 포럼 Vol.19 No.55
The paradigm of urban regeneration has shifted from the physical construction center to a cultural based policy, and the key factor is culture as a source of urban competitiveness. As urban regeneration using culturenomic has recently emerged as a key issue in the world, Korea is actively pushing forward with the strategy of culture and art. Therefore, this study explores an implementation of sustainable culture space creation through the activist of '7017 Seoul', which is the most recently opened Seoul city's cultural novels urban regeneration project, physical, environmental, and life effects, and suggests the direction of cultural norms implementation for urban regeneration. From this analysis, we could identify the effects of economic, physical, environmental, and daily life while explaining sustainable attributes in the execution of culturenomics and suggest implications for the direction of cultural nominals for urban regeneration. 1) the urban environmental structures are considered of streets, 2) lack of cultural consideration from the part of public projects 3) lack of sustainability of public spaces. This study is to refer to be a culture- based urban regeneration plan as a basis for the regular review of the sustainable experience - based culture norms strategy at the present time, which is being activated in each city in Korea. 최근 세계적으로 컬처노믹스(cultrenomics)를 활용한 도시재생이 핵심이슈로 떠오르면서 국내에서도 문화와 예술을 전략화 하여 적극적으로 추진하고 있다.문화는 도시경쟁력의 원천이 되므로 도시재생의 패러다임은 물리적 건설 중심에서 문화를 기반으로 하는 정책으로 전환 되었다. 이는 다시 말하면 도시의 랜드스케이프(landscape)를 전환하는 일과도 연관한다. 이 연구는 문화기반 도시재생관련 계획에 따른 개발이 각 도시마다 활성화 되고 있는 현 시점에서 지속 가능한 체험기반 컬처노믹스 전략의 일정의 점검과 기초자료로 활용되기 위한 보고용 연구이다. 따라서 본 연구는 가장 최근 개장한 서울시의 대표적인 컬처노믹스 도시재생 사업인‘서울로 7017‘의 액티베이터를 대상으로 하여 지속가능 한 문화 공간의 창출을 위한 그 실행에 관하여 알아보았다. 이 분석을 통해서 컬처노믹스의 실행에 있어서 지속 가능한 속성을 밝히면서 경제적, 환경적, 생활적 측면의 세부적 효과를 규명하고 도시재생을 위한 컬처노믹스 실행 방향의 시사점을 제시할 수 있었다. 조사 결과, 첫째, 문화콘텐츠를 실행하는 액티베이터의 물리 환경적 설치건축은 보행을 위한 경로로서 인지되고 있었다. 둘째, 다양한 사용자의 액티베이터의 공영 프로그램이 매우 부족하였다. 셋째, 지속적인 도시재생으로 컬처노믹스를 실행하기 위한 정치적 제도적인 지원과 관리가 없었다. 도시창조는 국가의 경쟁력이며 또한 국가 이미지이고 도시자체가 브랜드로서 경쟁력을 가지게 된다. 따라서 국가적 지원과 운영관리를 통해 시민의 삶의 가치와 지역의 사회, 경제적 활성화를 위한 지원체계구축이 추진되어야 한다.
DMBA(9,10-Dimethyl-1,2-Benzanthracene) 유도 악성섬유조직구종에 관한 실험적 연구
이혜수,김효열,강명재,최삼임,최호열,김상호 의과학연구소 1996 全北醫大論文集 Vol.20 No.2
To investigate the morphological characteristics and histogenesis of the malignant fibrous histiocytoma(MFH) induced by DMBA(9,10-Dimethy-1,2-Benzanthracene)m 0.1㎖ of 2% DMBA liquid paraffin solution was injected into the knee joint cavities of the Sprague Dawley rats(3 times, 4 weeks interval), thereafter, histologic and enzyme histochemical staines were performed. The obtained results were as follows : 1. Incidence rate of tumors was 94% in DMBA treated group, the first masses were palpated at 10-16 weeks after DMBA injection, and expired at 24 to 33 weeks. 2. The size of the first palpated masses were 2.0×1.4cm on the average, and size of the last palpated masses at death were 5.7×3.8×3.6cm on the average. 3. Grossly, most of the tumors developed single, and were nodular, hard, and well encapsulated. The cut surface disclosed whitish yellow fibrous tissue, and necrosis, hemorrhage, and cyst formation were noted. 4. Microscopically, the findings were compatible with typical form of MFH, storiform-pleomorphic type. Most of the tissues revealed storiform, fascicular, and cartwheel arrangement of the plump fibroblasts, and pleomorphic histiocytes with single or several nucleated giant cells, bizarre cells, vacuolated cells, and myofibroblast like cells. Frequent mitosis were shown. And locally, myxoid change, vascular proliferation, and severe inflammatory cell infiltration with necrosis were observed. 5. PAS positive cells with varing degree of stainity, collagen and reticulin fibers stained with trichrome, van Gieson, and reticulin stains were demonstrated. Myofibroblastc cells were stained with red color for trichrome stain, but cross striations were not observed in PTAH stain. 6. Acid phosphatase activity was strong in almost malignant cells, but alkaline phosphatase and nonspcific esterase activities were not recognized. Above findings are compatible with malignant fibrous histiocytoma and suggest that this tumor originated from undifferentiated mesenchymal cells having the capacity for differentiation toward histiocyte and fibroblast.
Mepirizole 誘導 十二指腸潰瘍의 發生機轉 및 治療過程에 關한 實驗的 硏究
이혜수,윤윤호,정태섭,박승창,최호열,김상호 의과학연구소 1993 全北醫大論文集 Vol.17 No.2
To Investigate the pathogenetic mechanism of the mepirizole-induced duodenal ulcers, measurement of the acidity and amount of the gastric juice, comparison of the gross and histopathologic findings of the duodenal ulcers caused by oral, subcutaneous, intraperitoneal, and intramuscular administration of the mepirizole(200mg/kg), and observation of the effects of the truncal vagotomy to mepirizole-induced duodenal ulcers were performed. And their healing processed were observed. The results were as follows : 1. In group of oral administration of mepirizole, the gastric acidity was increased, but the amount of gastric juice was decreased with the passage of time in comparison with normal control group. 2. The duodenal ulcers were produced in all methods of mepirizole administration, especially in oral and subcutaneous administration groups, incidence rates were 90 and 100%, ulcer indices were 21.1+4.6 mm2 and 33.6+6.3em2, but duodenal perforation rates were 20% or less and there was no death case regardless of methods of administration. 3. After vagotcmy, duodenal ulceration by mepirizole was significantly inhibited in both short(1, 4 weeks) and long (1 year) time passed groups. 4. The healing of the mepirizole-induced duodenal ulcers were rapidly accomplished in 15 days for the most parts under the gross and microscopic observation. From the above suggest that production of duodenal ulceration by mepirizole is the consquence of exposure of the duodenal mucosa to the action of gastric acid that overwhelm the normal defenses and their healing is rapidly accomplished.
胃癌 組織의 Lysozyme, Carcinoembryonic Antigen 및 Keratin에 對한 免疫 組織 化學的 硏究
이혜수,허장호,최호열 의과학연구소 1991 全北醫大論文集 Vol.15 No.1
Gastric cancer is the most common tumor in Korean. To investigate the significance of the immunohistochemical study using a immunoperoxidase technics on the formalin fixed, paraffin embedded section of the gastric cancer tissues, peroxidase-antiperoxidase stain for lyso- zyme, carcinoemvbryonic antigen(CEA) and keratin were carried out on the 68 cases of the gastric cancer of 27 cases of well differentiated adenocarcinoma, 14 cases of moderate differentiated adenocarcinoma, 22 cases of poorly differentated adenocarcinoma and 5 cases of the signer ring cell carcinoma, and 21 cases of the no- rmal gastric tissues. The results were as follows. 1. Rate of the positivity of the lysozyme on the gastric cancer was 69.1%(47/68). And rate and degree of the positivity was markedly decreased in the poorty differentiated adenocarcinoma compared with well differe- ntiated adenocarcinoma. 2. In the stain for the carcinoembryonic antigen, the rate of positivity was 83%(59/68), and moderate to st- rong positive reactions were shown independent of its differentiation. 3. Keratin in the normal and all gastric cancer tissues was not demonstrated. Above results suggest that detection of the lysozyme and carcinoembryonic antigen using a peroxidase-anti- peroxidase method are helpful to the diagnosis of the degree of differentiation of gastric cancer tissues.