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平胃散과 平胃散 構成藥物의 加減方이 摘出臟器, 抗瀉下作用 및 中樞神經系에 미치는 影響
柳逢夏,朴東源,柳基遠,金倫寬 慶熙大學校韓醫科大學韓醫學硏究所 1999 慶熙韓醫大論文集 Vol.22 No.1
The aim of this experimental study was to investigate the effects of Pyungwee-san samples on the movement of gastrointestinal smooth muscles, anticatharsis, and central nervous system by using rats or mice. Samples were divided into five groups : Sample-Ⅰ : Pyungwee-san(Atractylodes Rhizoma, Aurantii Nobils Pericarpium, Magnoliae Cortex and Glycyrrhizae Radix), sample-Ⅱ : Exclusion of Atractylodes Rhizoma from Pyungwee-san, Sample-Ⅲ : Exclusion of Aurantii Nobils Pericarpium from Pyungwee-san, Sample-Ⅳ: Exclusion of Magnoliae Cortex Rhizoma from Pyungwee-san, Sample-Ⅴ : Exclusion of Glycyrrhizae Radix from Pyungwee-san. The results were as follows : 1. All samples showed inhibitory effect on the motility of the isolated ileum and relaxant effect on the contracted ileum induced by acetylcholine chloride and barium chloride, these effects were dependent on their concentrations. 2. All samples in which sample-Ⅲ was exclude showed inhibitory effect on the motility of the rat fundus strip and relaxant effect on the contracted fundus strip induced by acetylcholine chloride and barium chloride, these effects were dependent on their concentrations. 3. Anticathartic effect of Pyungwee-san samples was appeared in sample-Ⅰ, sample-Ⅳ, sample-Ⅴ after drug medication in caster oil induced diarrhea. 4. Analgestic effect of Pyungwee-san samples on inhibition of writhing syndrome by acetic acid was recognized in sample-Ⅰ, sample-Ⅱ, sample-Ⅴ. 5. Effect of Pyungwee-san samples prolonging the hypnotic duration by pentobarbital-Na in Mice was shown in sample-Ⅱ, sample-Ⅲ. 6. Effect of Pyungwee-san samples on prolonging the time to death induced by strychnine was appeared in sample-Ⅳ(p<0.001). 7. Effect of Pyungwee-san samples on Picrotoxin-induced Convulsion in mice was appeared in all samples and on prolonging the time to death induced by strychnine was appeared in sample-Ⅱ, sample-Ⅲ, sample-Ⅳ. 8. Effect of Pyungwee-san samples on Caffeine-induced Convulsion in mice was appeared in sample-Ⅰ(p<0.01), sample-Ⅳ(p<0.05).
위암(胃癌)에 대(對)한 문헌고찰(文獻考察)-(근래(近來) 잡지(雜誌)를 중심(中心)으로)-
공현식,유봉하,박동원,유기원,Kong, Hyeon-Sig,Rhu, Bong-Ha,Park, Dong-Won,Ryu, Ki-Won 대한한방내과학회 1994 大韓韓方內科學會誌 Vol.15 No.1
This study was performed to investigate the gastric cancer through the journal of oriental medicine since 1990. The following results have been obtaied. 1. The Herb-medication in Gastric Cancer was composed to the oral-method and the injection-method. but, the oral-method was major and the injection-method rarely used. 2. In the treatment of Gastric Cancer, the Herb-medication that copperated with the operation and chemotherahpy was much more used 3. In the oriental medical therapy, the therapy for invigoration(補法) was common used. and the therapy for regulating vital energy(理氣), removing blood stasis(祛瘀), relieving pain(止痛), clearing away the heat evil (淸熱), removing toxic material(解毒) was used. 4. The following Herb was much more used to threat the Gastric Cancer.
실장산(實腸散)이 위장관(胃腸管)에 미치는 영향(影響)
공현식,유봉하,박동원,유기원,Kong, Hyeon-Sig,Rhu, Bong-Ha,Rark, Dong-Won,Ryu, Ki-Won 대한한방내과학회 1994 大韓韓方內科學會誌 Vol.15 No.2
In order to investigate the efficacy of Siljangsan by using the experimental animals, the action of gastric juice secretion, antiulcer. transport rates in the intestine and anti-cathartic action were studied. The following results were obtained. 1. Preventive effects on ulcer induced by pylorus-ligated and Ethanol-HCI were recognized 2. Suppression effects on gastric juice secretinon, free of acidity and total acidity were recognized, but pepsin output was not recognized. 3. For the transport ability of intestine of mice, the ability of small intestine was activated and large intestine was suppressed in the group administrated 4. Anti-cathatic action of mice induced by castor oil was recognized. According to above results, effect based on oriental medical reference was consistent with the actual experimental effect.