RISS 학술연구정보서비스

검색
다국어 입력

http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.

변환된 중국어를 복사하여 사용하시면 됩니다.

예시)
  • 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
  • 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
닫기
    인기검색어 순위 펼치기

    RISS 인기검색어

      검색결과 좁혀 보기

      선택해제
      • 좁혀본 항목 보기순서

        • 원문유무
        • 음성지원유무
        • 원문제공처
          펼치기
        • 등재정보
          펼치기
        • 학술지명
          펼치기
        • 주제분류
          펼치기
        • 발행연도
          펼치기
        • 작성언어

      오늘 본 자료

      • 오늘 본 자료가 없습니다.
      더보기
      • 무료
      • 기관 내 무료
      • 유료
      • KCI등재
      • KCI등재

        SNS 사이트 웹 접근성 수행 충실도가 이용률에 미치는 영향 - 시니어세대 사용자를 중심으로 -

        황현숙 한국브랜드디자인학회 2011 브랜드디자인학연구 Vol.9 No.3

        본 연구에서는 온라인에서 구축되는 친목기반 인맥 형성 서비스인 SNS가 웹 환경에서 특정집단 즉, 뉴 시니어 세대가 정보활동에 참여할 수 있도록 적절한 인터페이스를 제공하고 있는지 웹 접근성을 평가해 봄으로써 웹 접근성 수행 충실도 가 이용률과 관계가 있는가를 연구하였다. 이용률이 높은 4개의 SNS 사이트를 선정하고 웹 접근성 자동 평가 도구와 가이드라인의 준수가 특정 집단의 사용성 과 실제적인 관련이 있는가를 평가하기 위해 시니어세대를 대상으로 선정하였다. 웹 접근성 지침 1.0과 WCAG의 접근성 지침의 평가 결과 4개의 원칙 준수율에 대한 평균은 미투데 이, 트위터, 페이스북, 싸이월드 순으로 높은 준수율을 나타냈 다. 설문조사 결과 4개의 SNS 중 높은 이용률을 보이는 것은 페이스북, 트위터, 싸이월드, 미투데이 순으로 나타나 웹 접근 성과 실제 이용률에는 차이가 있는 것으로 나타났다. 그러나 이 4개의 SNS는 기본은 같으나 서비스의 구성이 다른 것이 웹 접근성 준수율의 차이로 해석된다. 본 연구 결과 시니어세대의 SNS사이트 이용률과 웹 접근 성은 연관이 있는 것으로 나타났다. 하지만 WCAG의 접근성 지침의 가중치와 실제 이용자의 가중치는 차이를 보이고 있 었다. 이결과는 특정 사용자 집단의 접근성에 관한 중요도가 달라지기 때문으로 해석된다. 따라서 사용자를 중심으로 항 목별 우선순위와 가중치 기준을 개발, 제시함으로 평가 점수 화하는 작업이 필요함을 시사한다. Through an evaluation of the web accessibility by exam ining whether SNS, an on line-established personal conn ection formation service, provides proper interfaces for specific groups, especially senior generations to participate in information activities, this study investigated if the per formance fidelity of web accessibility is related to the availability ratio. To investigate whether web accessibility evaluation tools and the observance of guidelines are actually related to a specific group’s availability, this study selected 4 SNS sites with a high availability ratio, especially for senior-g eneration users. As a result of evaluating the Web Acce ssibility Guideline 1.0 and the Accessibility Guideline of WCAG, it was found that me2day, Twitter, Facebook an d Cyworld show high observance rates on average for 4 principles in order. As a result of carrying out a survey, it was found that Facebook, Twitter, Cyworld and me2da y show high availability ratios in order among the four SNS sites, which indicates there is difference between web accessibility and actual availability ratios. However, it is interpreted that the different service formation of the 4 SNS sites leads to the different observance rate of web accessibility, although they have the same basic services. Overall, it was found that senior generations’ availability ratio of SNS sites is related to web accessibility. However, there is still difference found between the weight of the Accessibility Guideline of WCAG and the weight of actual users. This finding indicates that the importance of accessibility varies depending on specific user groups. Consequently, this finding implies that it is needed to carry out operations, which can evaluate and score each item, by developing user-oriented items and the order of priority and weight of all the items.

      • KCI등재

        찔레뿌리 추출물의 항산화능과 인간모유두세포의 성장인자 발현에 미치는 영향

        황현숙,황태현,표애자,주은화 한국피부과학연구원 2017 아시안뷰티화장품학술지 Vol.15 No.2

        Purpose: The anti-oxidant activity of active ingredients extracted from Rosa multiflora root was evaluated and effects of cell proliferation and growth factor expression were confirmed. Methods: Total polyphenol and flavonoid content of the active ingredients extracted from Rosa multiflora root was measured in various ways, as were 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity and nitrite scavenging activity. Further, the cell proliferation effects for human hair follicle dermal papilla cell (HFDPC) were measured using thiazolyl blue tetrazolium bromide (MTT) assay, as were the effects of promoting the expression of growth factors such as platelet derived growth factor subunit B (PDGFB), keratinocyte growth factor (KGF), insulin like growth factor 1 (IGF1), vascular endothelial growth factor (VEGF), hepatocyte growth factor (HGF), and epidermal growth factor (EGF) by Western blot. Results: The total polyphenol content of six kinds of Rosa multiflora root extracts was the highest in supercritical extracts (101.925 mg/g) and the total flavonoid content was the highest in supercritical extracts (14.365 mg/g). DPPH scavenging activity was the highest in methanol-sonication extracts (98.24%) and nitrite scavenging activity was the highest in supercritical extracts (55.86%). HFDPC was treated with 10, 100, and 500 μg/mL of Rosa multiflora root methanol-sonication extracts to determine cytotoxicity. The cell growth rate increased with increasing concentrations. The effects of the expression of growth factor protein were 135% greater in IGF1 and 126% greater in PDGFB. Conclusion: Rosa multiflora root extracts had no cytotoxicity but had excellent anti-oxidant ability. In addition, because the effects of promoting the expression of IGF1 and PDGFB were significant, it was confirmed that Rosa multiflora root extracts could be used as an antioxidant, functional cosmetic material, and as a natural material for hair restorer and a hair-growth promotion agent. 목적: 찔레나무(Rosa multiflora) 뿌리에서 유효성분을 추출하여 항산화 활성 평가, 세포증식효과 및 성장인자 발현촉진효과를 확인하여 천연성분을 이용한 기능성 화장품 및 육모제 소재로서의 활용 가능성을 탐색하였다. 방법: 찔레나무 뿌리에서 다양한 방법으로 유효성분을 추출하여 총 폴리페놀 및 플라보노이드 함량을 측정하였고, DPPH 라디칼 소거능과 아질산염 소거능을 측정하였다. MTT assay로 인간모유두세포에 대하여 세포 독성 효과를 측정하였으며, 웨스턴블롯을 통해 모발성장인자인 PDGFB, KGF, IGF1, VEGF, HGF, EGF의 발현촉진효과를 측정하였다. 결과: 찔레뿌리 추출물 6종의 총 폴리페놀 함량은 초임계 추출물(101.925 mg/g), 총 플라보노이드 함량은 초임계 추출물(14.365 mg/g)에서 가장 높게 나타났다. DPPH 소거능은 메탄올-초음파 추출물(98.24%)에서, 아질산염 소거능은 초임계 추출물(55.86%)에서 가장 높게 나타났다. 인간모유두세포에 찔레뿌리 메탄올-초음파 추출물을 10, 100, 500 μg/mL의 농도별로 처리하여 세포 독성을 확인한 결과, 처리농도 범위 내에서 세포 독성은 관찰되지 않았으며. 농도가 증가할수록 세포 생육도가 높았다. 웨스턴블롯을 통한 성장인자 단백질의 발현효과는 대조군 대비 IGF1은 135%, PDGFB은126%로 발현촉진효과가 높게 나타났다. 결론: 찔레뿌리 추출물은 독성이 없고 항산화능이 우수하였으며, IGF1과 PDGFB에 대한발현촉진효과가 높게 나타나 항산화제, 기능성화장품, 육모제 및 발모촉진제의 천연소재로서의 활용 가능성을 확인하였다.

      • KCI등재후보

        Poly(ADP-ribose)Polymerase 억제제가 신생백서의 저산소성 허혈성 뇌손상에 미치는 영향/1H 자기공명분광법을 이용한 연구

        황현숙,이정희,박평환,석은하,임근호,곽미정 대한마취과학회 2002 Korean Journal of Anesthesiology Vol.42 No.2

        Background : Poly (ADP-ribose) polymerase (PARP) has been described as an important candidate for mediation of neurotoxicity after brain ischemia. This study was purposed to evaluate the effects of a PARP inhibitor on hypoxic-ischemic injury in the neonatal rat brain. In this study, a highly potent inhibitor of PARP, 3, 4-Dihydro-5-[4-(1-piperidinyl) butoxy]-1 (2H)-isoquinolinone (DPQ) was investigated. Methods : Seven-day old Sprague-Dawley rat pups were used. The right common carotid artery was ligated under halothane anesthesia. After a recovery period of 3 hours, they were exposed to 8% oxygen at 37℃ for about 120 minutes. The animals were divided into four groups: the pre-treatment group (n = 13) and post-treatment group (n = 21) were given DPQ 10 ㎎/㎏ and the pre-control group (n = 7) and post-control group (n = 14) were given a vehicle for controls. Pre-treatment and pre-control groups were injected 30 minutes prior to the hypoxic injury while post-treatment and post-control groups were injected 30 minutes after the hypoxic period intraperitoneally. The right cerebral hemisphere of the rats were examined with localized ^1H magnetic resonance spectroscopy on day 1 and 7 after the hypoxic insult. Lipid/N-acetyl aspartate (Lip/NAA) and lipid/creatine (Lip/Cr) ratios were used as apoptotic markers. On day 14, the degree of brain injury was scored by morphological changes. Results : In the DPQ treated groups, the Lip/NAA and Lip/Cr ratios were lower than those of the control groups on day 1 after the hypoxic-ischemic injury (P < 0.05). However on day 7, only the ratios of the pre-treatment group were lower than those of the control group (P < 0.05). The degree of morphological changes of the brain injury on day 14 were lower in the DPQ treated groups (P < 0.05). Conclusions : These results suggest that DPQ exerts a neuroprotective effect in cerebral hypoxicischemic injury probably by inhibiting apoptosis especially in the early stage after an insult. Acute inhibiton of PARP can have a therapeutic value in preventing ischemic brain injury. (Korean J Anesthesiol 2002; 42: 228~240)

      • KCI등재후보

        The Effect of Core Muscle Training Program on Balance Ability

        황현숙,김년준 국제물리치료연구학회 2017 Journal of International Academy of Physical Ther Vol.8 No.2

        The purpose of this study was to investigate the effects of core muscle training on balance ability. Forty subjects in their 20s participated in a 6 week core muscle training program. Balance ability before and after the intervention were assessed and analyzed using the Romberg test, which was conducted on the floor, pedalo, and balancefit. The differences between the measurement methods of balance ability using varied platforms was also compared and analyzed. After the 6-week core exercise training program, the training group represented statistically significant increases in all 3 methods for static balance ability. In the control group, all 3 methods represented no statistically significant increases. Upon comparing the different methods of the Romberg test, there were no notable differences between conducting the test on varying platforms for both groups. This study suggests that the core muscle exercise training program increased the balance ability.

      연관 검색어 추천

      이 검색어로 많이 본 자료

      활용도 높은 자료

      해외이동버튼