소아기 중증근무력증 27례에 대한 임상적 고찰

손병희(Byeong Hee Son),황태규(Tae Gyu Whang),이순용(Soon Youg Lee) 대한소아신경학회 1994 대한소아신경학회지 Vol.2 No.1

Twenty-seven cases of myasthenia gravis in childhood were diagnosed and treated in the Department of Pediatrics, Inje University Hospital from February 1981 till February 1994 were reviewed clinically. Mean age of myasthenia gravis was 5.02±3.11 years of age and 16 cases(59.3%) were below the age of 5 years. Male to female ratio was 1:1.7. Most common initial clinical manifestation was ptosis noted all cases, followed by strabismus, diplopia, and impairment of lateral gaze. Edrophonium and neostigmine test were positive in all cases and antiacetylcholine receptor antibody was posiive in two cases among 3 in which antiacetylcholine receptor antibody study was done. There was no associated disease except one case of hyperthyroidism. Anticholinesterase therapy was tried in all case with 11 cases of remission, and predisolone was added in 12 cases who were not respond to anticholinesterase therapy with 9 cases of remission. Response to mestinon was not so effective(40.7%) and steroid was effective in juvenile myasthenia gravis that didn't respond to anticholinesterase therapy.

부산 및 경남지방 학생들의 상완 둘레 및 피부 두께의 통계적 관찰

황태규,정우영,박철환,최을임,고학준,이순용 인제대학교 1986 仁濟醫學 Vol.7 No.1

1984년 5월부터 1년간 부산 및 경남지역의 건강한 7세부터 15세까지의 학동 5,853명을 대상으로 상완 둘레 및 피부 두께를 측정하였기에 결과를 보고하는 바이다. The measurement of left mid-arm circumference and skinfold thickness (triceps, subscarpular and abdominal) by Holtain skinfold caliper was done on 5,835 healthy Korean children aged from 7 to 15 years, living in Pusan and Kyung-Nam urban areas. The results are summarized as follows: 1) The upper arm circumference of both sexes were increased rapidly from the age of 7 years (male, 17. ± 0.9 cm; female, 17.5 ± 1.2 cm) to the age of 15 years (male, 23.2 ± 1.6 cm; female, 23.0 ± 1.8 cm). 2) The triceps skinfold thickness of both sexes were lowest at the age of 9 years (male,7.2 ± 2.0 mm; female,7.6±1.4 mm). In the feamale, it was increased slowly until 15years of age but in the male, decreased after 13 years of age and the difference at 15 years of age was 3.4 mm. 3) The subscarpular skinfold thickness in male was lowest at the age of 9 years, 4.8±1.2 mm and in female, lowest at the age of 8 years, 5.1 ± 1.3mm. The change pattern in female was more rapidly increased than male and the results at 15 years of age in male was 5.8±2.1 mm, in female was 8.3 ± 1.3 mm. 4) The abdominal skinfold thickness of both sexes were lowest at 9 years of age (male, 4.4±1.7 mm; female, 4.8±1.3 mm) and the results at 15 years of age in male was 5.8 ± 2.1 mm, in female was 8.0±1.3 mm. 5) The change pattern of skinfold thickness was higher in female than in male after 10 years of age, unrelated with measured site. The result of skinfold thickness shows highest at triceps and lowest at abdomen.

부산지역 국민학교 학생들의 신체 발육과 비만 실태와 관한 조사

황태규 인제대학교 1984 仁濟醫學 Vol.5 No.1

부산 지역 국민학교와 사립국민학교 학생들의 신체 발육 상태와 비만아의 실태를 비교 파악하기 위하여 부산 지역 국민학교 학생 1,875명을 조사 대상으로 하여 국민학교 1학년부터 6학년까지의 신체 발육 상태를 정년적으로 조사하여 얻은 결과를 요약하였다. The author studied the status of physical development and obesity in 1,875 primary school children in Busan area, and followed up it's changes from their first grade to sixth grade in order to compare the differences between private school and general school children. The summarized results were as follows: 1.The value of physical development showed increasing tendency with school age and private school children had higher value than standard children group. 2.Ro¨hrer index shewed decreasing tendency with school age. 3.The rate of obese children based on Ro¨hrer index was 1.50% in male and 1.56% in female of standard children group, and 2.86% in male and 2.72% in female of primate school children.

녹색종 2 예

박승원,정우영,황태규,김철호,이순용 인제대학교 1985 仁濟醫學 Vol.6 No.2

저자들은 급성 골수성 백혈병의 소견을 보이면서 안구 돌출 및 신경증상을 동반한 2예의 녹색종 환자를 경험하였기에 문헌 고찰을 하였다. Two cases of chloroma were presented. They were admitted with the chief complaints of exophthalmos and various neurological symptoms. They had the pictures of acute myelomonocytic leukemia with the bone marrow aspiration and the peripheral blood smear, and neurological symptoms such as hearing disturbance and urinary incontinence in one case, and visual disturbance and hearing disturbance in the other, as well as exophthalmos. The related literatures were briefly reviewed.

소아 신경섬유종증 환자에 발생한 악성 신경초종

한영심,박선영,황태규,이순용 인제대학교 1998 仁濟醫學 Vol.19 No.2

신경섬유종증은 피부 색소침착, 피부와 신경계의 다발성 신경섬유종을 특징으로 하며, 악성 종양의 발생 위험이 크다. 그 중 악성 신경초종은 주로 사지에서 발생하는 가장 특징적인 종양이나, 소아 신경섬유종증에서는 발생이 드물어 국내 문헌에서 20세 이하에서 발생한 보고는 3예에 불과하고, 특히 10세 미만에서 발생된 예는 찾아 볼 수 없었다. 저자들은 신경섬유종증인 7세 여아의 흉곽에서 발생한 악성 신경초종 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Neurofibromatosis is characterized by cafe´-au-lait spots, multiple neurofibroma on the skin and nervous system, and high risk of malignancies. Of those malignancies, malignant schwannoma is one of the most important and develops usually on the extremities. However, in neurofibromatosis, associated malignancy is very rare in the age of childhood and malignant schwannoma has been only 3 cases below the alee of 20 years reported in the Korean literatures. Furthermore, associated malignant schwannoma below the age of 10 years has never been reported in the Korean literatures. We report a case of malignant schwannoma in the thorax in a 8-year-old girl with neurofibromatosis, with a brief review of the related literatures.

Reye 증후군의 예후와 관계되는 요인들

송민섭,김두권,황태규,이순용 인제대학교 1989 仁濟醫學 Vol.10 No.3

1984년 1월부터 1988년 7월까지 4년 7개월간 본원을 방문한 소아 중 Reye 증후군으로 진단된 41례를 대상으로 생존군과 사망군의 임상 증상 및 검사 소견을 비교하여 예후에 미치는 요인들을 분석하여 보았다. We experienced 41 cases of Reye's syndrome during 4□ years from January 1983 40 July 1988. We analyzed the clinical and laboratory findings and the following results were obtained as prognostic factors of Reye's syndrome. 1) The age distribution was between 3 months and 12 years of age. Statistically, there was no difference in mortality rate with regard to age. 2) The blood levels of ammonia(297.0±134.7㎍/dl)at the time of diagnosis in the patients who were dead were significantly higher than those(182.0±101.7㎍/dl)in the patients who were recovered(P<0.05). But the levels of blood glucose and CSF glucose(31.9±28.9mg/dl and 31.9±28mg/dl)at diagnosis in the patients who were dead were significantly lower than those(103.4±50.7mg/dl and 73.3±36.9mg/dl)in the patients who were recovered(P<0.05). 3) There was no statistical significance in GOT, GPT, LDH, PT and PTT between the two groups. 4) The higher the clinical stage at the time of admission, the higher the mortality. 5) The overall mortality was 36.5%(15 cases of the 41 patients).

소아 뇌막염에서 뇌척수액의 LDH활성도, GOT치, Cholesterol치에 관한 연구

정우영,박병욱,황태규,이순용 인제대학교 1986 仁濟醫學 Vol.7 No.4

뇌막염에서 뇌척수액 내에 존재하는 각종 화학 성분 및 효소의 변화를 초래함은 잘 알려져 있다. 저자들은 이들 중 뇌척수액의 LDH 활성도, GOT치, Cholesterol치를 측정하여 이들의 진단적 가치와 치료 결과 판정에서의 유용성을 조사하였다. LDH activity, GOT and cholesterol levels in CSF were prospectively studied on 43 cases of patients with bacterial, aseptic and tuberculous types of meningitis and 11 cases of control group who were admitted to our department since June 1985. The results obtained were as follows: 1.The LDH activity in CSF was significantly increased in patients with meningitis in all types compared with those of control group respectively (P<0.005). Among these the cases of bacterial meningitis revealed most prominent increment. 2.The LDH activity in CSF suggested a worthy role to differentiate bacterial meningitis from aseptic meningitis and also from tuberculous meningitis but in a lesser degree. 3.The GOT and cholesterol levels in CSF were significantly increased respectively in patients with bacterial meningitis compared with those of control group (P<0.005, P<0.025). 4.The GOT and cholesterol levels in CSF suggested a limited value for differential diagnosis of meningitides compared with those of LDH activity. 5.For the evaluation of treatment and prognosis, the LDH activity in CSF was relatively significant but those of GOT and cholesterol levels were not helpful.