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환자 맞춤형 대뇌동맥륜의 형상 조건에 따른 혈류역학 인자 분석
홍인의(Ineui Hong),오제훈(JeHoon Oh) 대한기계학회 2021 대한기계학회 춘추학술대회 Vol.2021 No.11
The Circle of Willis (CoW) is responsible for supplying blood form the heart to the cerebral arterioles and capillaries. Since CoW has a ring-like shape, three inlets (left & right internal carotid artery and basilar artery) and several outlets (middle cerebral artery, anterior communicating artery and posterior cerebral artery), it is difficult to analyze blood circulation and hemodynamics factors in blood vessels with an invasive method. To overcome difficulty, the computational fluid dynamics (CFD) is used for hemodynamics analysis. To analyze hemodynamics parameters, previous studies don’t consider the shape of CoW, but only the disease occurrence or the region of interest (RoI). In this study, Using CoW model and RoI model, comparing hemodynamics factors such as 3D streamline, wall shear stress and pressure according to models.
홍인이(In Iy Hong),최수근(Soo Keun Choi) 한국조리학회 2014 한국조리학회지 Vol.20 No.1
The purpose of this study is to develop value-added functional gruel by adding fresh burdock & burdock powder. For burdock, we put fresh burdock (1.0, 2.0, 3.0, 4.0%) and burdock powder(0.3, 0.6, 0.9, 1.2%) into burdock gruel and get results from mechanical tests and sensory tests. Moisture content of fresh burdock gruel increased with more addition of fresh burdock, while burdock powder gruel had less moisture content as the addition of burdock powder increased. Lightness and pH decreased in both groups as more amount of burdock was added. From the result of an attribute difference test, 4% fresh burdock gruel showed the strongest burdock flavor and astringent taste. Among the burdock powder groups, the gruel added with 1.2% burdock powder scored the highest point in color intensity, graininess, savory taste, astringent taste, thickness and aftertaste. For overall acceptability, the gruel added with 3% fresh burdock scored the highest point and the gruel added with 0.6% burdock powder was the highest among the burdock powder groups. Based on the results of this study, the gruel added with 0.6% burdock powder and the gruel added with 3% fresh burdock were the optimum for their good characteristics and overall acceptability when produced.
족삼이혈(足三里穴) 전침 자극이 유문부 부분폐색이 된 흰 주의 위(胃) 배출능에 미치는 효능
홍인아,윤상협,Hong, In-A,Yoon, Sang-Hyub 대한한방내과학회 2009 대한한방내과학회지 Vol.30 No.1
Objective : The aims of this study were to observe how body weight and gastric morphology were changed and whether gastric emptying was impaired in rats with partial pyloric obstruction. and to evaluate whether electroacupuncture was able to restore delayed gastric emptying. Methods : Partial pyloric obstruction was induced by wrapping a nonabsorbable rubber ring around the 1st portion of the duodenum for 2 weeks. Body gain and morphologic changes of stomach were investigated and compared with normal intact rats. Gastric emptying was measured by numbering expelled glass of beads in rats. Rats were divided into 4 groups(non-acupuncture, manual acupuncture. 3Hz-electroacupuncture. 60Hz-electroacupuncture). Stimulus intensity in two electroacupuncture groups was 1.2 times of pain threshold. Results : Partial pyloric obstruction produced a significant loss of body weight and induced a significant increase of gastric surface area. The 60Hz electroacupuncture-stimulated group significantly restored the delayed gastric emptying compared to the other groups of rats with partial pyloric obstruction. Conclusion : 60Hz electroacupuncture stimulation on Zusanli(ST36) showed significant restoration of delayed gastric emptying in rats with partial pyloric obstruction.
기능성 소화불량증 환자의 위장관 부교감 신경, 위 유문부의 기능 및 임상양상에 대한 조사 (한방병원 내원 환자를 중심으로)
홍인아,윤상협,Hong, In-A,Yoon, Sang-Hyuh 대한한방내과학회 2008 대한한방내과학회지 Vol.29 No.3
Objectives : The aim of this study was to evaluate gastrointestinal parasympathetic nerve activation and pyloric valve function in patients with functional dyspepsia through analysis of bowel sounds and to investigate clinical characteristics associated with the parameters of bowel sounds. Method : We surveyed clinical characteristics of patients by using a questionnaire about functional dyspepsia. Bowel sounds were recorded for 15 minutes during fasting state and for 40 minutes during postprandial state. We then classified the patients into 3 groups by abnormal states of bowel sounds, specifically by the percentage of B.S. and dominenet frequency, and studied clinical characteristics in each group. Results : Among the 182 subjects, patients who had low activity of parasympathetic nerve were 25.8% and showed a tendency of female-dominant, family history and more frequent abdominal pain. Those who had pyloric valve disturbance were 24.1% and showed no tendency by sex distribution, family history and complained of indigestion sensation. Patients who had both disorders were 10.9%, and their clinical characteristics were non-specific. Conclusion : Analysis of bowel sounds may be useful in evaluating pathophysiological factors of functional dyspepsia.
구취환자의 구강건조와 기허${\cdot}$기울 변증의 상관성 분석
김소연,김유승,홍인아,허원영,엄국현,이선령,윤상협,류봉하,김진성,Kim, So-Yeon,Kim, Yoo-Seung,Hong, In-A,Hur, Won-Young,Eom, Guk-Hyeon,Lee, Seon-Young,Yoon, Sang-Hyub,Ryu, Bong-Ha,Kim, Jin-Sung 대한한방내과학회 2007 대한한방내과학회지 Vol.28 No.1
Objectives : This study investigated the correlation between dry mouth and comprehensive diagnosis of Qi xu and Qi yu in patients with halitosis. Methods : We surveyed 124 halitosis patients by reviewing the questionnaires from the Halitosis Clinic in the Hospital of Oriental Medicine, Kyunghee University from January 2004 to March 2006. The halitosis questionnaires contained self-awareness of halitosis, self-assessed severity of halitosis, dry mouth and taste abnormality. Among comprehensive diagnosis of Qui Xue Shui, Qi xu and Qi yu parts were investigated by questionnaire and physical examination, and each Qi xu and Qi yu part scores were summed. Winkel tongue coating index was estimated by investigator, the level of volatile sulfur compounds were measured by halimeter, and salivary function was assessed by salivary scan test. All patients were divided into two groups based on salivary scan test (salivary function normal and decreased). Results : Qi xu score of halitosis patients with decreased salivary function was higher than normal halitosis patients. There was highly significant correlation between Qi yu score and dry mouth, and another significant correlation between self-assessed halitosis severity and dry mouth was noted. Conclusions : The results of this study suggest that Qi yu condition influences dry mouth in halitosis patients, and halitosis is affected by dry mouth. Therefore. we assume that treating Qi yu condition can be a potentially effective way of treating dry mouth and halitosis.
허원영,류봉하,김유승,홍인아,김소연,엄국현,이선령,윤상협,Hur, Won-Young,Ryu, Bong-Ha,Kim, Yoo-Seung,Hong, In-A,Kim, So-Yeon,Eom, Guk-Hyeon,Lee, Seon-Young,Yoon, Sang-Hyub 대한한방내과학회 2007 대한한방내과학회지 Vol.28 No.4
A pancreatic pseudocyst is the most common cystic lesion in the pancreas. There are several treatment methods with variable results. Recently, conservative treatment has been preferred because it has fewer complications. In this case, a 37-year-old male patient had pancreatic pseudocysts with upper abdominal pain, left upper back pain, diarrhea, weight loss, and general weakness. We prescribed him Banchongsangamibang (蟠蔥散加味方). For about 1 year, he was treated with oriental medicine. All of his pancreatic pseudocysts disappeared on abdominal CT follow-up and the symptoms mostly subsided. There had been no recurrence of pancreatic pseudocysts on abdominal CT follow-up after 1 year.
기능성 소화불량증 환자에서 침구 처치 후 다채널 위전도 소견의 변화
김유승(Yoo Seung Kim),류봉하(Bong Ha Ryu),김진성(Jin Sung Kim),홍인아(In A Hong),박영선(Young Sun Park),정용재(Yong Jae Jung),오승환(Seung Whan Oh),한가진(Ga Jin Han) 한의병리학회 2010 동의생리병리학회지 Vol.24 No.1
The aim of this study was to investigate the effects of traditional Korean medical therapy in patients with functional dyspepsia evaluted using multi-channel electrogastrography. Before the treatment, the EGG of 14 outpatients (male 3, female 11) with functional dyspepsia were recorded and their dominant frequency(DF), percentage of gastric slow waves, percentage of Power ratio, and percentage of slow wave couplings were analysed. For 8 weeks, the patients received acupuncture treatment. After 8 weeks, EGG was rechecked and compared with the previous data. After treatment, normogastria was significantly increased in channel 1 and channel 3(53.70 ±18.94% vs 72.64 ±15.49% in channel 1, P<0.05; 79.74 ±18.09 vs 90.86 ±8.86 in channel 3, P<0.05). arrythmia was significantly decreased in channel 3(14.34 ±15.21 vs 5.93 ±6.90, P<0.05). The patients who had less severe decrease in EGG indexes showed improvement of those indexes through 8 weeks of outpatient care. EGG channel 3 was shown to be the most adequate standard of evaluation. But there was no significant improvement in slow wave coupling rate which is a new index of multichannel EGG.