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홍성국,서광윤,이병윤 고려대학교 의과대학 1991 고려대 의대 잡지 Vol.28 No.1
This study was performed to evaluate the characteristics of childhood in schizophrerucs. Using the questionnaire to 107(53 male, 54 female) schizophrenics and 108(54 male, 54 female) controls, the results were obtained as follows. 1. In schizophrenics, the family size was larger, the economical state at present was poorer, and the genetic loading both in nuclear family and extended family were higher than controls. The mothers of schizophrenics had more difficult problems involved with pregnancy and delivery than controls. The schizophrenics had more difficult temperaments such as lower response to stimulation and more irregular pattern in activity level in their childhood than controls. In neurointegrative functioning, the schizophrenics had more abnormalities such as delayed developmental milestones and abnormal integrative motor functions than controls. Disturbances in social functioning at each developmental stages were found more frequently in schizophrenics than controls. In developmental problems, the schizophrenics showed more difficulties especially involved with control of excretory functions than controls. The schizophrenics were more subjected to negative family environment and had more separation experiences with parents before 7 years of their age. The parents of schizophrenics had low expectation for their children's achievement and showed lax discipline and marital discord. The schizophrenics has poor family relationship and residential environment. In general stressors, the schizophrenics were more exposed to physical i11ness, physical or sexual threats, emotional shock, and social traumatic experience than controls. In protective factors, the schizophrenics had negative and passive personal disposition, poor supportive family milieu and external support system. 2. Delivery complication, separation with parents before 7 years of their age, and sexual threat were found more freguently in female schizophrenics than male schizophrenics. On the other hand, the parental overexpectation and intrusion to their child and residential moving out were found more freguently in male schizophrenics than female schizophrenics. 3. The differences in neurointegrative functioning between the schizophrenics and controls were seen significantly in infancy, the differences in social functioning were in early childhood, and the differences in developmental problems were in middle childhood. 4. In discriminating schizophrenics from controls, the external support system had the highest discriminant function coefficients. And the factors of family size, genetic loading in nuclear family, family stressors, temperaments, positive personal disposition, general stressors, neurointegrative functioning, genetic loading in extended family, and social functioning had next discriminant function coefficients in this order. With above selected factors, probability to discriminate patient groups from controls was 89.81%.