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$CC1_4$의 간장독작용(肝臟毒作用)에 미치는 Thyroxine의 영향(影響)
홍기성,천연숙,Hong, Ki-Sung,Cheon, Yun-Sook 대한약리학회 1980 대한약리학잡지 Vol.16 No.2
Calvert et al. formulated the hypothesis that carbon tetrachloride ($CCl_4$) acted on the central nervous system to produce and intensify sympathetic discharge which resulted in anoxic necrosis of the liver. Recknagel suggested that the essential feature of $CCl_4$ hepatotoxicity depended on the cleavage of it to $CCl_3$(free radical) and the peroxidative decomposition of cytoplasmic membrane structural lipids. And there are many reports which show the increase of adrenergic activity in hyperthyroidism. In this paper, the influence of thyroxine on the hepatotexicity of carbon tetrachloride was investigated in mice. The results obtained were summarized as follows; 1) Hepatic total lipid and lipid peroxide contents were slightly decreased by L-sodium thyroxine injection(4mg/kg/day for 4days or 6days), but hepatic glycogen content was significantly decreased. 2) Hepatic total lipid and lipid peroxide contents and serum lactic dehydrogenase activity were significantly increased by $CCl_4$ (4 ml/kg single dose or triple dose: 4ml/kg/day for 3days), but hepatic glycogen content was significantly decreased. 3) The increase of hepatic total lipid and lipid peroxide contents and serum lactic dehydrogenase activity induced by $CCl_4$ were significantly inhitited by the pretreatment of thyroxine. 4) The decrease of hepatic glycogen induced by $CCl_4$ was not affected by the pretreatment of thyroxine.
홍기성,서영호,김동욱,Hong, Ki-Sung,Seo, Young-Ho,Kim, Dong-Wook 한국정보통신학회 2012 한국정보통신학회논문지 Vol.16 No.1
본 논문에서는 고부가가치의 디지털 홀로그램 콘텐츠를 저작하여 새로운 디지털 홀로그램 콘텐츠를 확보하는 방법을 제안한다. 깊이정보는 스테레오 정합방식으로 획득한 시차정보로부터 얻은 깊이정보와 TOF (time-of-flight) 방식의 깊이카메라로 촬영한 깊이정보를 모두 사용한다. 각 종류의 깊이정보와 변환방법을 사용하여 깊이정보를 변환하거나 합성하고 이를 CGH 방법으로 연산하여 디지털 홀로그램을 획득한다. 또한 CGH 연산으로 획득한 디지털 홀로그램의 선형성을 기반으로 기 생성된 디지털 홀로그램 콘텐츠를 합성하여 새로운 디지털 홀로그램 콘텐츠를 획득하는 방법도 제시한다. 제안한 방법을 다양한 깊이정보와 디지털 콘텐츠를 대상으로 실험하여 이 방법이 디지털 홀로그램 콘텐츠의 저작방법으로 효과적임을 보인다. This paper is to propose a method to obtain a new digital hologram content, a high value-added digital content, by manipulating one or more existing digital hologram contents or depth informations. For the depth informations, we use both the ones converted from disparities by stereo matching and the ones taken by time-of-flight (TOF) depth cameras. For them, we analyze the properties and their differences for the two kinds of depth informations and propose a conversion method to homogenize them. By using them, we propose a method to convert and synthesize the depth informations to calculate a new CGH. Also, we propose a method to get a new digital hologram content by synthesizing the digital holograms themselves according to their linearity. The proposed methods are experimented with various depth informations and digital holograms to show that they are very effective as the manipulating methods for digital hologram contents.