일측폐 마취

한종인 대한마취과학회 2005 Korean Journal of Anesthesiology Vol.48 No.5

개에서 Isoflurane 과 Nitroglycerin 의 조절저혈압 마취후 Doxapram 이 심혈관계에 미치는 영향

한종인,이춘희,김치효 대한마취과학회 1991 Korean Journal of Anesthesiology Vol.24 No.4

Isoflurane causes little myocardial depression, rapid onset and recovery during controlled hypotensive anesthesia. Nitroglycerin, vasodilating agent, has short plasma half-life and myocardial protective effect, is easy to cantrol, and has no direct toxic effect. Doxapram hydrochloride(doxapram Hcl), respiratory stimulant, has been found to be safe and significantly potent, but also has significant pressor effect when larger doses are administered. The purpose of this study was to evaluate the effects of doxapram on the hemodynamics after isoflurane and nitroglycerin-induced hypotensive anesthesia in dogs. Hemodynamic measurement including the value of left ventricular pressure, aortic pressure, pulmonary eapillary wedge pressure, pulmonary artery pressure, heart rate, cardiac output, maximal and minimal dP/dT were determined in 8 dogs before doxapram Hcl administration, Smin, 15min and 30min after doxapram Hcl administration. 1) Left ventricular pressure and aortic pressure increased at 5min and 15min after doxapram Hcl administration but did not change significantly at 30min compared to the preadministration values. 2) Pulmonary capillary wedge pressure and pulmonary artery pressure increased significantly at Smin and 15min, but did not change significantly 30min compared to the preadministration values. 3) Heart rate increased significantly at Smin, but did not change significantly at 15min and 30min compared to the preadministration value. 4) Cardiac output and body temperature did not change significantly at 5min, 15min compared to the preadministation values. 5) Maximal dP/dT increased signifieantly at Smin and 15min, but did not change at 30min compared to the preadministration value, minimal dP/dT increased significantly at 5min, but did not change at 15min and 30min compared to the preadministration value.

노인환자에서 척추마취시 Power Spectrum에 의한 심박수 변이도의 평가

한종인 梨花女子大學校 醫科大學 醫科學硏究所 1999 EMJ (Ewha medical journal) Vol.22 No.2

Objectives : Spectral analysis of heart rate variability(HRV) resulted in a characteristic power spectrum with two main regions, a high frequency at 0.15-0.5Hz(HFP) corresponding to the parasympathetic system and a low frequency at 0.017-0.l5Hz(LFP) corresponding to both parasympathetic and sympathetic influences. The ratio of low : high frequency(LFP/HFP) has been postulated as an index of sympathetic activation. We propose that the LFP/HFP ratio will provide important information concerning autonomic nervous system activity during spinal anesthesia especially geriatric patients. Methods : LFP, HFP and LFP/HFP were checked in 30 patients at the baseline and 5, 10, 15, 20, 25 and 30 minutes after subarachnoidal block. We divided patients into two groups: group 1 is 15 patients under 60 years old and group 2 is 15 patients over 65 years old, and we compared those parameters in both groups. Results : Spinal anesthesia did produce a significant decrease in LFP and HFP in both groups. But sympathetic-parasympathetic balance(LFP/HFP) increased at 5 minutes after spinal block. In group 1, LFP/HFP decreased at 10 minutes after spinal block, thereafter increased gradually. In group 2, LFP/HFP decreased at 10, 15 and 20 minutes and increased at 25 and 30 minutes after spinal block. Conclusion : These data suggest that autonomic tone decreased with spinal anesthesia and sympathetic-parasympathetic balance decreased for a long time in geriatric patients.

Conceptual design of e-fuel production process for carbon capture and utilization

한종인,김호재,이철진 한국공업화학회 2023 한국공업화학회 연구논문 초록집 Vol.2023 No.1

맥박산소계측기를 이용한 수술후 일상적인 산소투여의 타당성에 관한 연구 : 수술후 저산소혈중에 영향을 미친는 요인 Determining factor on the Postoperative Arterial Hypoxemia

한종인,이춘희,이귀용,정락경,황현정 대한마취과학회 1994 Korean Journal of Anesthesiology Vol.27 No.10

Routine use of supplemental oxygen(O2) in the recovery room traditionslly has been used to minimize the incidence of hypoxemia. However with the advent of continuous noninvasive monitoring by pulse oximetry is routine administration of O₂ necessary? We hypothesized that administration O₂ as needed based on pulse oximetry dats, would effect without compromieing patient care. And factors that might influence the incidence of post-operative hypoxemia were analyzed. On hundred thirty eight adult (≥18yrs) patients were enrolled in the study. During recovery room care, when O₂ saturation(SpO₂) was continuously more than 94%, no supplemental O₂ was given. When SpO₂ was less than 94%, supplemental O₂ was given by face mask(O2 51/min). SpO₂ and Aldrete score(AS) were measured at preoperatively, at the end of anesthesia, on arrival in the recovery room, at 10 min, 20 min and 30 min after arrival in the RR and at discharge. The results are as follows: 1) Supplemental O₂ was unneeessary in the 55.8% of patient for the dration of the recovery room stay. 2) A significant multiple correlation was found between low SaO₂ level, while breathing room air on arrivsl in the recovery room and preoperative SpO₂, weight and Aldrete score on arrival in the recovery room. With the above results the authors concluded that in as much as pulse oximetry monitoring is now standard in the recovery room, administration O₂ as need based on the pulse oximetry data would effect without compromising patient care, and that preoperative oxygen saturation and weight are the main factors influencing early postopertative hypoxemia in this study.

요추 경막외 마취에서 카테테르 삽입 방향과 지각차단범위

한종인,김종학,이춘희,이귀용,김치효,정락경,백은주 대한마취과학회 1997 Korean Journal of Anesthesiology Vol.33 No.2

Background : Endoscopic urologic surgery including transurethral resection of prostate(TURP) requires adequate sacral analgesia for insertion of resectoscope. But epidurally administered local anesthetic does not produce anesthetic effects uniformly. Failure to completely block S1 during epidural anesthesia because of the large size of nerve root has been noted. The purpose of this study to compare the relation between catheter direction and sensory anesthesia. Methods : Thirty patients scheduled for endoscopic urologic surgery were enrolled. The epidural catheter was inserted at L3-4 using a standard 18 gauge Tuohy needle. In group A(n=15), the Tuohy needle with bevel pointed in a cephalad direction during catheter insertion. In group B(n=15), it pointed caudally. And the catheter was introduced 3 cm into the epidural space. After test dose, 2% lidocaine 5 cc, 0.5% bupivacaine 5 cc and 2% lidocaine 3 cc were administered with fractionate dose through it. The extent of the sensory anesthesia to loss of cold sensation and pin prick test was measured every 5minute for 30 minutes. Results : Analgesia spread to loss of cold sensation and pin prick test was no significant statistical difference between the two groups. In 15 minutes after injection of surgical dose, complete blockade in L5, S1 dermatome was present in both groups. Conclusion : Our results conclude that epidural catheter direction is not significantly influence the epidural anesthetic spread including sacral area in continuous lumbar epidural anesthesia in elderly patients. (Korean J Anesthesiol 1997; 33: 291∼296)

Ketamine으로 마취유도한 마취유도한 서혜부 탈장수술 받는 영아와 유아에서 Sevoflurane의 MAC incision의 차이

한종인,김치효 대한소아마취학회 2003 소아마취 Vol.7 No.2

호기말 산소농도를 이용한 사전 산소투여

한종인,오은정,이춘희,이귀용,정락경 대한마취과학회 1994 Korean Journal of Anesthesiology Vol.27 No.11

Preoxygenation is a standard anesthetic technique for preventing hypoxemia during the in- duction of anesthesia. This is achieved by alveolar denitrogenation while ventilating the lungs with 100% oxygen. Until recently there was no satisfactory nitrogen monitoring device except mass spectrometry which is not generally available. We used a convinient and readily available measuring technique to evaluate the effectpreoxygenation. In 31 healthy volunteers breathing 100% oxygen, end-tidal oxygen concentration have been measured at 15 seconds interval from the start of preoxygenation. A circle system was flushed with 100% oxygen and flow rate of 8 liter per minute. The gas sampling line of the Capnomac II (Datex, Finland) was placed in nasal cavity. At 1, 2, 3 minutes, mean end-tidal oxygen concentration was 78.7%, 89.2%, 91.9 % respectively. End-tidal nitrogen concentration was approximately 16.1 %, 5.8%, 3.2%. We conclude end-tidal oxygen concentration is a good indirect measure of denitrogenation.

영어 의사소통능력 수행평가 방안 연구

한종임(韓宗姙),전지현(全芝賢) 성곡언론문화재단 2001 성곡논총 Vol.32 No.3

CLONIDINE 의 경구 전처치가 척추마취에 미치는 영향

한종인,이춘희,한경림,김치효 대한마취과학회 1994 Korean Journal of Anesthesiology Vol.27 No.1

Oral clonidine premedication appears to inhibit the outflow of sympathoadrenal activity and adrenocortical hormone release, thereby decreasing the minimum alveolar anesthetic concentration of inhaled anesthetics and stabiliring cardiovascular system. It has been reported that oral clonidine premediacation for spinal anesthesia, similar to intrathecal administration of clonidine, has prolonging effect of sensory and motor blocks. The purposes of this study are to assess the effects of oral clonidine premedication on the duration of tetracaine spinal anesthesia, and the hemodynamic changes during spinal anesthesia. Twenty patients undergoing hemorrhoidectomy, TURP, and device removal of lower extremity under spinal anesthesia (0.5% hyperbaric tetracaine), were given diazepam 10 mg orally (Group 1, n=10) or clonidine 150 ug orally (Group 2, n=10) 1 hour before tbe anestbesia. The results were the following, (1) No significant differences was noted between two groups in either the maximum level of sensory extension or time to maximum level of sensory blockade between two groups. In Group 2, the time for two-segment regression was prolonged compared with group 1, but not significant. The time for regression to L1 was significantly prolonged in Group 2 (238±37.74min) compared with Group 1 (167.6±25.85min)(P$lt;0.05). (2) The number of patient in Bromage's scale score 3 of motor blockade between 180min and 260min after spinal anesthesia was 10 times higher in Group 2 compaired with Group 1 (P$lt;0.05). (3) In Group 1, the lowest systolic blood pressure during spinal anesthesia was significantly low compared with that before premedication (P$lt;0.05). In Group 2, systolic blood pressure before spinal anesthesia, mean systolic blood pressure during first 20mins of spinal anesthesia and the lowest systolic blood pressure were significantly reduced respectively comparing with those before premedication. Significant difference (P$lt;0.05) was noted between Group 1 and 2 in mean systolic blood pressure during the first 20 mins of spinaansthesia and in lowest systolic blood pressure during spinal anesthesia. In both groups, the lowest heart rate was significantly lower after than before premedication (P$lt;0.01), but the difference in the amount of heart rate change between two groups was not significant. In conclusion, prolongation of sensory and motor blocks of spinal anesthesia with hyperbaric 0.5% tetracaine may be accomplished with oral premedication of 150 ㎍ clonidine without serious clinieal complication.