http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : 한정원 (검색결과 288 건)
- 무료
- 기관 내 무료
- 유료
-
-
한정원,이종혁,윤수민,Aerin Yoon,황도빈,Hwa K Lee,Min S Kim,이유진,Won J Yang,박선영,윤홍덕,김효리,정준호 생화학분자생물학회 2016 Experimental and molecular medicine Vol.48 No.-
The C-terminal domain of RNA polymerase II is an unusual series of repeated residues appended to the C-terminus of the largest subunit and serves as a flexible binding scaffold for numerous nuclear factors. The binding of these factors is determined by the phosphorylation patterns on the repeats in the domain. In this study, we generated a synthetic antibody library by replacing the third heavy chain complementarity-determining region of an anti-HER2 (human epidermal growth factor receptor 2) antibody (trastuzumab) with artificial sequences of 7–18 amino-acid residues. From this library, antibodies were selected that were specific to serine phosphopeptides that represent typical phosphorylation patterns on the functional unit (YSPTSPS)2 of the RNA polymerase II C-terminal domain (CTD). Antibody clones pCTD-1stS2 and pCTD-2ndS2 showed specificity for peptides with phosphoserine at the second residues of the first or second heptamer repeat, respectively. Additional clones specifically reacted to peptides with phosphoserine at the fifth serine of the first repeat (pCTD-1stS5), the seventh residue of the first repeat and fifth residue of the second repeat (pCTD-S7S5) or the seventh residue of either the first or second repeat (pCTD-S7). All of these antibody clones successfully reacted to RNA polymerase II in immunoblot analysis. Interestingly, pCTD-2ndS2 precipitated predominately RNA polymerase II from the exonic regions of genes in genome-wide chromatin immunoprecipitation sequencing analysis, which suggests that the phosphoserine at the second residue of the second repeat of the functional unit (YSPTSPS)2 is a mediator of exon definition.
-
한부모가족지원사업의 효과성 연구 - 한부모가족 심층면접을 중심으로 -
한정원 부산대학교 여성연구소 2014 여성학연구 Vol.24 No.2
본 연구는 한부모가족지원사업의 효과성을 검토하려는 목적으로 심층면접을 중심으로 여성과 남성의 성역할과 사회적, 경제적 차별성에 근거한 성인지 분석을 제시하였다. 본 연구결과로는 첫째, 한부모가구주의 성별에 따라 빈곤의 원인과 과정이 달랐으며 탈빈곤 요인과 가능성에 있어서도 차이가 있었다. 둘째, 남성한부모가족에 비해 여성한부모가족의 경제적 취약성은 나이가 어린 아동을 양육하고 있는 경우 더욱 심화될 소지가 있다. 셋째, 자녀양육 문제에 있어 한부모가구주의 성별에 따라 필요한 서비스 욕구가 다름을 알 수 있었다. 넷째, 한부모가구주의 성별과 가구 형태에 따른 다양한 정서적 지원 프로그램 마련과 홍보가 필요하다. 따라서 한부모가족지원사업은 탈빈곤과 자립이라는 목적을 달성하기 위하여 성별, 가구별 특성을 고려한 세부사업 및 지원대책을 제시하여야 할 것이다. With the purpose of exploring effectiveness of single-parent family support service, this article uses in-depth interviews of beneficiaries and social workers implying gender analysis. Research results are as follows: first, causes, processes, ways and possibilities of post/poverty depend on gender; second, mother with younger children are more reliable to face economical risk; third, there are gender differences regarding child care issues and demanding services; forth, there emerges necessity of diverse mental support programmes and their public advertisement. Therefore, single-parent family support service is to suggest more specific program according to gender and personal situation in order to accomplish its own goal of post-poverty and independence.
-
-
Dementia Strategies using Welfare-technology
한정원 한국융합학회 2022 한국융합학회논문지 Vol.13 No.5
South Korea faces elderly care crisis with both low fertility rate and rapid ageing rate. Long-term care insurance in 2008 has taken care burden from family to nation. However, few options, lack of tailored services, and unstable community care plan caused blankness of care in some areas. Especially, increasing dementia rate has become an emergent social issue. Welfare technology could be a useful alternative to fill out the gap between demand and supply. Using FGI method on two groups(high-risk dementia group and MCI group), intimacy, accessibility and preventive way of dementia with welfare technology are analysed in this paper. Despites of a few differences of dementia progress, interests towards technology are expressed. More suggestions using TV and normal telephone to improve daily independence are presented as well. Amongst MCI group, help-service for technology-use at ADS and linkage ways of in-home services are also suggested.
-
-
-
-
-
한정원 한국문화공간건축학회 2015 한국문화공간건축학회논문집 Vol.- No.49
The purpose of this study is to understand the development trend of recent tile products which have beenrecognized as passive finish material through case studies on the design collaboration of global tile brands, and to explore therole of finish material as a means for creative design. Also it is significant to provide data for the domestic tile industry whichis still staying in elementary phase of production. For this, theoretical background on the collaboration performed in variousareas was organized, and the function and role of tile as a finishing material were identified through a document research. Asthe next step, characteristics of products and brands were analysed with the global tile brands in which active collaborationswith renowned designers are in process as the subject of case study. The results are as follows; Firstly, tile is evolving tomore active and three-dimensional media instead of being a two-dimensional finish. Secondly, there were attempts to escapethe limitation of material by integrating joints as design elements or reinterpreting the uniform regularity and allowing change. Thirdly, the function of tile was expanding to the substitute material for wallpaper or furniture finish, so that the materials of tileare changing to glass or metal. Finally, pursuit of differentiation by special theme and advanced concept was accomplishedthrough designer collaboration. Domestic tile industry has a number of problems to be solved nowadays, and the differentiationstrategy through a unique design development is necessary and new markets could be created through it.
ScienceON연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
