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한유민,Hyuk Yoon,Cheol Min Shin,Seong-Joon Koh,Jong Pil Im,Byeong Gwan Kim,Joo Sung Kim,Hyun Chae Jung 거트앤리버 소화기연관학회협의회 2016 Gut and Liver Vol.10 No.4
Background/Aims: The optimal route for iron administration in anemic patients with inflammatory bowel disease (IBD) has not been determined. The aim of this study was to compare the efficacies of parenteral and oral iron therapy in IBD patients in Korea. Methods: A retrospective multicenter study was performed. Patients who had been administered parenteral iron were matched to the controls with oral iron at a 1:1 ratio according to age, sex, and type of IBD. Results: Patients that received parenteral iron exhibited increases in hemoglobin levels of ≥20% from the baseline at lower doses and in shorter durations (p=0.034 and p=0.046, respectively). In the multivariate analysis, parenteral iron therapy appeared to be more efficient than oral iron therapy, but this difference was not statistically significant (hazard ratio [HR], 1.552; 95% confidence interval [CI], 0.844 to 2.851; p=0.157). Patients with ulcerative colitis responded better to iron therapy than those with Crohn’s disease (HR, 3.415; 95% CI, 1.808 to 6.450; p<0.001). Patients with an initial hemoglobin level of 10 g/dL or higher responded poorly to iron therapy (HR, 0.345; 95% CI, 0.177 to 0.671; p=0.002). Conclusions: Parenteral iron therapy appears to be more efficient than oral iron therapy. Physicians should focus on the iron deficiency of IBD patients and consider parenteral iron supplements in appropriate patient groups.
Colon Capsule Endoscopy: Where Are We and Where Are We Going
한유민,Jong Pil Im 대한소화기내시경학회 2016 Clinical Endoscopy Vol.49 No.5
Colon capsule endoscopy (CCE) is a noninvasive technique for diagnostic imaging of the colon. It does not require air inflation or sedation and allows minimally invasive and painless colonic evaluation. The role of CCE is rapidly evolving; for example, for colorectal screening (colorectal cancer [CRC]) in average-risk patients, in patients with an incomplete colonoscopy, in patients refusing a conventional colonoscopy, and in patients with contraindications for conventional colonoscopy. In this paper, we comprehensively review the technical characteristics and procedure of CCE and compare CCE with conventional methods such as conventional colonoscopy or computed tomographic colonography. Future expansion of CCE in the area of CRC screening for the surveillance of polyps and adenomatous lesions and for assessment of inflammatory bowel disease is also discussed.
Endoscopic Removal of a Migrated Coil after Embolization of a Splenic Pseudoaneurysm: A Case Report
한유민,Jong Yeul Lee,Il Ju Choi,Chan Gyoo Kim,조수정,Jun Ho Lee,Hyun Beom Kim,Ji Min Choi 대한소화기내시경학회 2014 Clinical Endoscopy Vol.47 No.2
Splenic artery pseudoaneurysms can be caused by pancreatitis, trauma, or operation. Traditionally, the condition has been managedthrough surgery; however, nowadays, transcatheter arterial embolization is performed safely and effectively. Nevertheless, several complicationsof pseudoaneurysm embolization have been reported, including coil migration. Herein, we report a case of migration of thecoil into the jejunal lumen after transcatheter arterial embolization of a splenic artery pseudoaneurysm. The migrated coil was successfullyremoved by performing endoscopic intervention.
최지민,김주성,이창현,한유민,이민종,장동기,권지혜,임종필,김상균,정현채 대한장연구학회 2013 Intestinal Research Vol.11 No.2
Crohn’s disease is a chronic inflammatory disease that can involve the entire gastrointestinal tract. Several studies indicate that Crohn’s patients with long disease duration have an increased risk of small bowel or colorectal cancer. In Korea, only a few cas-es of Crohn’s disease-related small bowel or colorectal cancer have been reported. Here, we described 3 cases of colorectal can-cer and 2 cases of small bowel cancer in patients with Crohn’s disease. Among 5 patients, 3 had Crohn’s disease-related lower gastrointestinal malignancy and the other 2 had sporadic lower gastrointestinal malignancies. Since the diagnosis of Crohn’s disease-related lower gastrointestinal malignancy tends to be delayed, the development of malignancy should be considered in patients with long duration of Crohn’s disease if patients have refractory symptoms despite intensive medical treatment. Surgi-cal consultation should not be delayed. (Intest Res 2013;11:127-133)
다발성 간전이를 동반한 췌장신경내분비종양 환자의 장기생존 1예
장동기,박진명,이민종,최지민,최영훈,한유민,유정주,류지곤 대한췌담도학회 2013 대한췌담도학회지 Vol.18 No.2
A 50-year-old female with epigastric pain was diagnosed as pancreatic neuroendocrine tumor with multiple liver metastases by radiologic imaging studies and liver biopsy. After 4 times of transarterial chemoembolizations (TACE), pylorus-preserving pancreaticoduodenectomy (PPPD) was performed and Grade 2 pancreatic neuroendocrine tumor was confirmed. Although new liver metastases were detected after the surgery, no further treatment has been given due to very slow growth of the metastatic lesions. The patient has survived for over 7 years with no symptoms related to cancer. This case suggests that a patient with pancreatic neuroendocrine tumor with multiple liver metastases could become a long-term survivor by aggressive locoregional treatments including surgery. Therefore, active multidisciplinary approaches should be considered for advanced pancreatic neuroendocrine tumors.