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      • 골의 거대세포종양의 재발과 면역조직화학적 표지자(MCM3, Ki-67 그리고 HH3)의 발현율과의 연관성

        하종경,정훈,김용주,이관희,최경업,Ha, Jong-Kyoung,Jeong, Hoon,Kim, Yong-Ju,Lee, Kwan-Hee,Choi, Kyoung-Eob 대한근골격종양학회 2007 대한골관절종양학회지 Vol.13 No.2

        목적: 골의 거대세포종양의 재발과 면역조직화학적 표지자와의 연관성을 연구하였다. 대상 및 방법: 골에서 유발된 거대세포종양 10례를 대상으로 하였다. 6명은 남자, 4명은 여자였다. 모든 환자는 수술 전 생검을 통해 확진 후 수술을 시행하였다. 방사선학적 분류는 Enneking grading system에 의하여 이루어졌다. 면역조직화학적 연구를 위해 MCM3, Ki-67 그리고 HH3 표지자가 사용되었다. 면역조직화학적 검사는 Microarray block을 사용하여 시행하였다. 결과: 10례 중 3례(30%)에서 같은 위치에서 재발되었다. 재발된 3례 중 2례는 방사선학적 단계 상 단계 2였고, 1례는 단계 1이었다. 면역조직화학적 표지자의 발현율이 방사선학적 단계 1보다 2, 3에서 증가되었다. 하지만 결과의 일관성이 없어 세포 증식율과 방사선학적 단계의 연관성은 판별하기 어렵다. 평균 MCM3 표지자의 발현율은 재발하지 않은 종양에서 11.2%, 재발한 종양에서 7.2%였다. Ki-67은 12%, 8.9% 였고, HH3는 66.9%, 75.4%였다. MCM3 와 Ki-67 표지자는 재발한 종양에서 오히려 감소된 결과를 보여 재발율과는 연관이 없을 것으로 생각된다. HH3표지자는 재발한 종양에서 증가된 소견을 보여 거대세포종양의 재발과 연관이 있음을 보여주었다. 결론: 본 연구는 면역조직화학적 표지자 중 HH3표지자가 거대세포종양의 재발 가능성을 판정하는데 기준이 될 수 있을 것으로 생각된다. Purpose: To evaluate association of giant cell tumors recurrence between markers of proliferation cells (MCM3, Ki-67 and HH3) Materials and Methods: Ten case of giant cell tumor of bone were reviewed. The patients were six males and four females (mean age: 33 yrs). All patients were done operation after biopsy. The radiologic grading was determined according to Enneking grading system. The immunohistochemical stains of MCM3, HH3, and Ki-67 were done with Microarray block. Results: The three cases of 10 cases (30%) were recurred at same sites. Two case of recurrence was grade II according to radiologic features. The remaining case was grade I. The expression rate of immunohistochemical markers in radiologic grade 2 and 3 were more increased than grade 1. But there was not association between radiologic grading and proliferation of tumor cells because result data was not coherence. Mean MCM3 labeling index of non-recurred case was 11.2%, recurred case was 7.2%. Ki-67 was 12% vs. 8.9%, respectively and HH3 was 66.9 % vs. 75.4%, respectively. Thus there was no association between local recurrence and immunohistochemical Ki-67, MCM3 expression rate. But HH3 marker expression rate was increased in recurred cases compared to non-recurred cases. Conclusion: Our study suggests that HH3 immunohistochemical marker can be a useful prognostic factor.

      • KCI등재

        패션 인터넷 쇼핑몰에서의 위험지각과 정보원 활용이 충동구매행동에 미치는 영향

        하종경,Ha, Jong-Kyung 한국생활과학회 2011 한국생활과학회지 Vol.20 No.5

        The purpose of this study was to investigate the impulse buying behavior of men and women in their twenties, who have experiences of purchasing on internet shopping malls, when they buy fashion products. The data in this study was statistically analyzed using factor analysis, reliability coefficient, and multiple regression analysis using SPSS 14.0. The findings are as follows. First, factor analysis revealed five factors of impulse buying behavior during the purchase of fashion products on internet shopping malls: affective impulse buying, provocative impulse buying, situational impulse buying, reminder impulse buying, and pure impulse buying. Second, factors of perceived risk when purchasing fashion products on internet shopping malls included product quality, payment, service, and economy. Third, sources of information included personal sources of media for fashion professionals, commercials and sponsorship, and promotion. Fourth, the effect of the perceived risk on impulse buying behavior was investigated and the result showed that the perceived risk had a statistically significant influence on impulse buying behavior. Finally, the effect of the information source on impulse buying behavior was investigated and the results showed that the use of information sources had a statistically significant influence on impulse buying behavior.

      • KCI등재

        온라인 패션뷰티 소비자의 충동구매 유형별 마케팅 정보 활용에 관한 연구

        하종경(Jong-Kyung Ha) 한국인체미용예술학회 2013 한국인체미용예술학회지 Vol.14 No.4

        The purpose of this study is to attempted to analyze differences between use of sales promotion and fashion beauty information by the type of impulse buying in order to classify online fashion beauty consumers by the type of impulse buying and analyze the use of related marketing information. The data were analyzed by factor analysis, cluster analysis, one-way ANOVA and Duncan test. The following results were obtained: First, impulse buying behavior was classified into five types: affective impulse buying, provocative impulse buying, situational impulse buying, reminder impulse buying and pure impulse buying. Second, in terms of subordinate dimension of impulse buying behavior, it was classified into three types of consumer groups. Third, according to analysis of differences in the use of marketing information by the type of impulse buying in online fashion beauty consumers, a significant difference was observed in the limited use of sales promotion information by the type of impulse buying.

      • KCI등재

        TV 홈쇼핑에서의 쇼핑성향에 따른 위험지각과 화장품 구매행동에 관한 연구

        하종경(Jong Kyung Ha) 한국인체미용예술학회 2015 한국인체미용예술학회지 Vol.16 No.2

        This paper aims to analyze the shopping orientation of female consumers in their 20's purchasing cosmetics via TV home shopping, accompanying risk perception, and cosmetic purchasing behaviors. The analysis results are described below: 1. Four shopping orientation elements purchasing cosmetics via TV home shopping are luxury brand shopping orientation, brand loyalty shopping orientation, systematic search shopping orientation, and impulsive shopping orientation. 2. The risk perception related to purchasing cosmetics via TV home shopping had three elements: quality risk perception, delivery risk perception, and payment method risk perception. 3. In accordance with the classification on consumer type focusing on shopping orientation elements in TV home shopping, there are three classes: systematic brand loyalty group, progressive shopping orientation group, and positive shopping orientation group. 4. For the risk perception by shopping orientation type in TV home shopping, the risk perception on quality or delivery showed a significant difference. 5. The analysis of the purchasing behavior difference by shopping orientation type found a significant difference in purchasing time priority (**p≤.01), number of watching TV (*p≤.05), and preferred channel (**p≤.01) by shopping orientation type. 6. For the correlation between shopping orientation and risk perception, luxury brand shopping orientation (p≤.01), systematic search shopping orientation, and impulsive shopping orientation (p≤.05) showed a correlation in all risk perception elements.

      • KCI등재
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      • KCI등재
      • KCI등재

        모바일 쇼핑동기가 뷰티 어플리케이션의 속성과 채택에 미치는 영향

        하종경(Jong-Kyung Ha) 한국콘텐츠학회 2021 한국콘텐츠학회논문지 Vol.21 No.9

        본 연구는 20대 소비자를 대상으로 뷰티제품의 모바일 쇼핑동기와 애플리케이션 속성을 분석하고 모바일 쇼핑동기가 뷰티 어플리케이션의 속성과 어플리케이션의 채택에 미치는 영향을 분석하였으며 그 결과는 다음과 같다. 첫째, 모바일 쇼핑동기는 유희성, 편리성, 충동성으로 구분되었으며 뷰티 어플리케이션 속성은 콘텐츠, 커뮤니티, 지속적 관리로 분류되었다. 둘째, 모바일 쇼핑동기는 선호하는 뷰티 모바일 어플리케이션 채택에 유의한 영향을 미치는 것으로 나타났는데 유희성은 뷰티 전문브랜드 앱과 뷰티쇼핑몰 앱에, 충동성은 온라인 종합 쇼핑몰 앱과 뷰티커뮤니티 앱에, 편리성은 TV홈쇼핑 기반 앱에 영향력이 있는 것으로 나타났다. 셋째, 모바일 쇼핑동기는 뷰티 어플리케이션 속성에 유의한 영향을 미치는 것으로 나타났다. 콘텐츠 속성에는 유희성, 편리성, 충동성이 유의한 영향이 나타났고, 커뮤니티 속성에는 유희성이, 지속적 관리에는 충동성이 영향력이 있는 것으로 나타났다. This study attempted to analyze the influence of mobile shopping motivation on the attributes and selection of beauty applications among consumers in their 20s, and the results found the following: First, mobile shopping motivation was classified into the categories of playfulness, convenience, and impulsiveness while beauty application attributes were divided into contents, community, and continuous management. Second, mobile shopping motivation was found to have a significant influence on selection of mobile beauty applications. Specifically, playfulness affected professional brands and beauty shopping mall apps, while impulsiveness revealed an effect on online shopping malls and beauty community apps. In addition, convenience showed an influence on TV home shopping apps. Third, mobile shopping motivation had a statistically significant effect on beauty application attributes. Specifically, playfulness, convenience, and impulsiveness revealed a statistically significant influence on contents, while playfulness also affected beauty communities. In addition, impulsiveness affected continuous management.

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