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      • SCOPUSKCI등재

        위 (胃) 십이지장궤양환자에서 (十二指腸潰瘍患者) Madecassol ( centella asiatica ) 의 사용경험

        박경남(Kyung Nam Park),신현성(Hyun Sung Shin),최일균(Il Gyun Choi),이민호(Min Ho Lee) 대한소화기학회 1982 대한소화기학회지 Vol.14 No.1

        N/A In order to elucidate the effect of titrated extract of Centella Asiatica(TECA) on peptic ulcer, the drug was given to a total of 40 patients with peptic ulcer including 25 cases of gastric ulcer and 15 cases of duodenal ulcer. The results obtained were as follows: Of 15 patients with peptic ulcer including 9 cases of gastric ulcer and 6 cases of duodenal ulcer who received TECA alone, 14 cases(93%) exhibited a definite improvement in subjective symptoms and 11 cases(73%) showed healing of the ulcer under endoscopic and radiological observations. 2) Of 14 patients of peptic ulcer who received TECA along with antacid, 13 cases showed an improvement in subjective symptoms and 11 cases(78%) exhibited healing of the ulcer. 3) Of 11 patients with peptic ulcer who served as control, 5 cases exhibited an improvement in subjective symptoms, but there were no sign of healing in observation. 4) Activities of serum transaminases, content of blood urea nitrogen and concentrations of serum electrolytes in patients ivith peptic ulcer were determined before and after administration of the drugs and were observed to be unchanged.

      • KCI등재후보

        고혈압으로 인한 좌심실비대에 미치는 항고혈압제의 효과

        김성근(Sung Keun Kim),이종영(Jong Young Lee),정덕자(Duk Ja Jeong),정동균(Dong Gyun Jeong),최조영(Cho Young Choi),최일균(Il Gyun Choi),이상용(Sang Young Lee) 대한내과학회 1990 대한내과학회지 Vol.39 No.3

        N/A In has been recently suggested that left ventricular hypertrophy (LVH) in patients with hypertension is a very useful predictor of increased cardiovascular morbidity and mortality. So the therapeutic goals of antihypertensive therapy in hypertensive patients with LVH are in the reduction of LVH. In these days angiotensin converting enzyme (ACE) inhibitor has been chosen as a first line drugs of anti-hypertensive therapy. In order to evaluate the efficacy of antihypertensive drugs in reduction of LVH (as a result of administrated captopril and / or diuretics or prazosin and / or diuretics treatment), we examined 75 cases who had antihypertensive drugs with follow-up periods of over 6 months. They were groups into two, group 1 and 11, The group 1 (37 cases: 14 males, 21 females, mean 57.0±8.7 years) had been administrated prazosin and / or diuretics and group II (38 cases: 17 males, 23 females, mean 54.8±10.5 years) had been administrated captopril and/or diuretics. We observed the effect of BP control, reduction in cardiothoracic ratio with chest roentgenogram, symptoms and laboratory abnormalities between pretreatment and 6 months after treatment in two groups. And echocardiographic measurements were observed between pretreatment and after treatment in 13 cases of group II. The results were as followings: 1) Age, sex, duration of hypertension and class of hypertension were not different significantly in two groups. 2) The blood pressure was reduced significantly from 2 weeks after treatment in two groups. But the difference of BP reduction in two groups was not stastically significant. 3) The cardiothoracic ratio in chest roentgenogram was reduced after 6 months therapy than pretreatment in two groups and the difference of cardiothoracic ratio reduction was significant in group II than the group 1. 4) Severity of symptoms were reduced after treatment than pretreatment in both groups but the difference of reduction degree was not significant in two groups. 5) The abnormal laboratory findings were reduced after treatment than pretreatment. But no significance was found in the laboratory parameters except cardiothoracic ratio. 6) Interventricular septal wall thickness, posterior wall thickness and left ventricular mass were measured by echocardiogram. They were more reduced significantly after 6 months treatment than pretreatment in 13 cases of group II.

      • KCI등재후보
      • 무증상 T파 역위의 수술과 관련된 심전도 변화

        최일균,변동일,이종영,이상용,정덕자,최조영,이정균 한양대학교 의과대학 1989 한양의대 학술지 Vol.9 No.2

        Cardiac arrhythmias during operation have been increased because the number of patients with cardiovascular disease, especially symptomatic or asymptomatic ischemic heart disease, has increased and cardiac arrhythmias can be a warning that the patient is under physiologic or anesthetic distress and that rapid correlation is necessary. To reduce the operation risk is major concern and preliminary screen is important as one of cardiac origin risk, the role of silent myocardial ischemia must be evaluated. But there has been rare studies for the ECG abnormalities during operation related to T wave inversion on preoperative ECG. In order to investigate the frequency, duration, relation to the site of inverted T wave and characteristics of arrhythmia or ST-T change, we started this study. Preoperative ECG had been performed to 1,872 patients who were prepared general anesthesia, there were 48 patients (2.56%) of only T wave inversion without accompanying symptoms of ischemic heart disease. We observed the 48 patients with ECG monitoring in operation room from anesthetic induction to recovery, but could not observe any electrocardiological abnormalities especially ST-T changes or arrhythmias compared with preoperative ECG except one case (2.1%) of sinus bradycardia. And the amplitude of inverted T wave was not shown statistically significant changes between preoperative ECG and intraoperative or postoperative ECG. It is concluded that there will be no problems in the anesthetic procedure for the operation in the patients with asymptomatic T wave inversion and will be no need to postpone the operation for performing the other studies to confirm ischemic heart disease. So ECG monitoring may be more important in the patients with asymptomatic T wave inversion during general anesthesia for operation.

      • KCI등재

        身體化 患者의 呼訴에 關한 言語學的 硏究

        김종주,최일균,정용균 大韓神經精神醫學會 1992 신경정신의학 Vol.31 No.5

        Each major physical part has a special value and symbolic meaning for the person. Such meaning tends to be unconscious and to reflect intrapsychic conflicts and defenses. The symbolic meanings appear to be determined in part by childhood experiences. But it is very important to distinguish whether the ethnic differences are a result of a different vocabulary usage for expressing distress. A sample of 165 somatizers was selected from two groups of 73 referred patients from the department of medicine and of 92 directly visiting ones to the psychiatry of Inchon Christian Hospital during one year period from March 1989 to February 1990. The complaints were described according to their own languages on the intial interviews, and classified into the somatic and the psychological ones. Somatic complaints were discussed on the semantic and the etymological aspects of Korean words of bodily languages and sensory verbs, and on their psychodynamic meanings. Each patient had average 6.45 somatic complaints. The referred patients had the complaints, particularly related to abdominal symptoms about two times more than the directly visiting ones, which were presented most frequently among all body areas. And the referred patients had more complaints related to chest, but the directly visitings had more complaints related to head. These results can be said that the patients with abdominal and chest complaints tend to visit on internists and then to be referred to psychiatrists. They had greater tendencies to somatize their intrapsychic conflicts than the directly visitings. The more patients with head complaints visited psychiatrists directly, and they seemed to accept psychiatric help more freely on their symptoms. There were no significant differences on the complaints related to back and extremities between two patient groups. Korean words such as 배〔bae, meaning of belly〕or 속〔sok, meaning of insides〕 to describe abdomen had the meanings to designate digestive organs. Etymologically the word, 입〔yip〕. with meaning of mouth as an orifice of digestive organs had the same origins as leaves of plants, which had symbolic meanings of mouth as an accepting site of plants. Korean word of head, 머리meori〕, had meanings such as the big, the top and first. Korean words, “가슴이 아프다”〔gasmi apuda〕 had the definitional meaning of chest pain, and the reactive one of psychic distress. But Korean description such as 가슴앓이 [gasm-ari] means the sufferings on chest, which translation is inadequate and insufficient, and was complained of frequently by patients suffering from “Hwabyung”, Korean folk illness, as the symptoms of feelings of a fist-sized mass in the lower chest and the upper abdomen, and of heat sensation. In Korean language, chest designates heart and breath, which are meaned the life because the cessation of either was recognized as a sign of death. The Chinese characters 心臟〔simjang〕to designate the heart have the meaning of “organ of mind.” The heart was thought as the chief organ for emotion, because of the central organ for circulation and the location for experiencing palpitation frequently associated with emotional excitings. Among the sensory verbs, the various verbs of organic sense appeared most frequently on all body areas, and some of the specific verbs of organic sense on the most appropriate physical parts. The verb of pain sense, 아프다〔apuda〕had the most frequency, particularly on the head. This verb and the other verb of pain sense, 아리다〔arida〕had the same origin from the word, 알〔al, meaning of egg〕, and therefore tow verbs of pain sense had the meanings of pain to lay an egg and to break an egg-shell. Therefore pain has the connotative meaning of developmental processes. Pain complaints serve to establish a legitimate relation between patient and doctor, and may be one way of seeking reassurance and support through a recognized and socially accepted relation. On the pain complaints related to abdomen, the word of belly(배) was followed by 아프다, and the insides(속) by another verb of pain sense, 쓰리다〔ssurida〕. The words of arms and leg(팔다리〔paldari〕), and hands and feet(손발〔sonbal〕) were followed by the verb of pain sense, 저리다 〔jeorida〕. A series of complaints on digestive organs starts from anorexia, and through the lumps on throat, nausea or vomiting, at last, arrives at indigestion and abdominal pain. These eating and digestive complaints may bring the greater attention and sympathetic responses from environments. There were several complaints of heavy sweating, fatigue, and loss of strength. These complaints suggested the longstanding strong influences of Chinese medical concepts on Korean people, such as exhaustion, weakness, and emptiness. Therefore some Korean people try to seek compulsively the restorative drugs and food, raionalizing their psychic distress by the name of “somatization”. These results suggest that the complaints of Korean somatizers are expressed through the bodily languages and sensory verbs with somewhat characteristic etymological and semantic qualities. These qualities are reflected on the psychodynamics of Korean somatizers. Further studies will contribute to the understandings of Korean depressives and somatizers.

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